Grover's Disease (Transient Acantholytic Dermatosis): 5-Minute Pathology Pearls

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  • เผยแพร่เมื่อ 1 พ.ย. 2024

ความคิดเห็น • 32

  • @JMGardnerMD
    @JMGardnerMD  3 ปีที่แล้ว +1

    A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

  • @ta_nimal2023
    @ta_nimal2023 4 ปีที่แล้ว +12

    How is Grover's prevented and how is Grover's treated?

  • @RaulRodriguez-sh6vb
    @RaulRodriguez-sh6vb 2 ปีที่แล้ว

    I have always found Dermpath very difficult with different patterns and overlapping features but since I started watching your videos I think is becoming understandable and easier for me!!! Thank you a lot

  • @loujain1591
    @loujain1591 20 วันที่ผ่านมา

    So helpful please add clinical pictures to make it perfect 🙏🏻

  • @nashrunner456
    @nashrunner456 3 ปีที่แล้ว +7

    OK. Now, tell us about an effective treatment for Grover’s, please.

    • @JMGardnerMD
      @JMGardnerMD  3 ปีที่แล้ว +5

      As a pathologist, I only diagnose skin disease, I don’t treat it. So I’m not a treatment expert. But my general understanding is that Grover’s can be difficult to treat and frustrating for patients. If you are suffering from it, I am sorry to hear it. Best wishes for good health.

  • @carlybalter1020
    @carlybalter1020 ปีที่แล้ว

    Just found out I have Grovers Disease. 37 women here and heard more men get it. I believe mine comes from stress. I'm very small and do not sweat a lot. I am glad they finally figured it out after 2 years.

    • @JMGardnerMD
      @JMGardnerMD  ปีที่แล้ว

      Sorry to hear that. I know it can be a really frustrating skin problem for patients. And even though the classic presentation is older men and sweating a lot, it can definitely occur outside that setting. I’ve diagnosed it in younger adult women before. Best wishes for health and healing.

    • @dominiquemiller7342
      @dominiquemiller7342 ปีที่แล้ว

      I am also a female sufferer and was diagnosed in my mid-20s. I'm now 31 (so much for it being transient! 😫) and luckily the affected area is smaller, but it comes and goes on my chest constantly. Living in FL it gets bad in the summer.

  • @pravoslavn
    @pravoslavn ปีที่แล้ว +1

    For what it is worth, Doc ... I have been treated for Grover's for 15 years by a Dermo-Doc who has been in that specialty for 40 years. He insisted Grover's is NOT an auto-immune condition (which I have always doubted) and treated me with Triamcinolone cream, topically applied, PRN, and with injectable Kenalog when things got really bad. For another reason, I began taking N-Acetyl Cystiene (an amino acid supplement) three monbths ago, 600 mg 2X daily. Within a month, my Grover's symptoms abated by 90%.

  • @PhillGraaf
    @PhillGraaf 2 ปีที่แล้ว +4

    Hey my friend...
    I have Grover's disease and I'm only 28. I've had it for about 7 years and it always starts either in winter when I have lots of clothes on or.. right now when it is very hot and I am sweating very much. I am living in Queensland, Australia right now and it is unbearable... What would you suggest for a treatment? I feel like nothing really helps...
    I would very much appreciate if you could give a little comment on my question 🙏🏼

    • @JMGardnerMD
      @JMGardnerMD  2 ปีที่แล้ว +2

      So sorry to hear this! Unfortunately I only know how to diagnose this, but I don’t have experience with treating it. I have heard it can be difficult to treat and uncomfortable so I’m sorry you are dealing with it. Please see your dermatologist so they can confirm diagnosis and give you best advice about treatment options. Best wishes for health and healing.

    • @ladyvirgo013
      @ladyvirgo013 ปีที่แล้ว +1

      My dermatologist gives a cortisone cream but it's not helpful at all. I do best with tea tree oil

    • @PhillGraaf
      @PhillGraaf ปีที่แล้ว +1

      @@ladyvirgo013 how do you use it and what does it do?

    • @ladyvirgo013
      @ladyvirgo013 ปีที่แล้ว

      @Living4Jesus4Ever I was only getting so far with the Tea Tree Oil, unfortunately I stepped it up to a steroid cream. (Not my first choice) but after months of trying to manage it, I decided to use what my skin doctor recommended

  • @ferhatozden
    @ferhatozden 4 ปีที่แล้ว

    Beautiful. Would like to hear from you how to approach to biopsies of pemphigus group diseases.

    • @JMGardnerMD
      @JMGardnerMD  4 ปีที่แล้ว +2

      Will add that to my list

  • @bysykler4959
    @bysykler4959 9 หลายเดือนก่อน

    How deep do these structures exist into the skin and might some of these sites be removed via freezing/ nitrogen? I have a number of seemingly static areas. Thanks!

  • @remimazorrahorts9176
    @remimazorrahorts9176 5 ปีที่แล้ว +1

    Really cool! I always learn a lot with your videos, tahnk you very much!
    Is there any clue or tip to distinguish between Grover's and Darier's disease? I mean histologically, of course.

    • @JMGardnerMD
      @JMGardnerMD  5 ปีที่แล้ว +4

      Thx! If it’s big and multifocal I start thinking of Darier, but honestly they can look totally identical microscopically and clinical info is the key to truly distinguishing them.

  • @TheCMcKean
    @TheCMcKean ปีที่แล้ว

    Hi Jerad, my shave biopsy only came back with epidermal hyperplasia with hyperkeratosis and serum crust.... would that mean I have Grovers? I never got an actual answer from my dermatologist and they just continue to throw medicines at me that don't work. Please help me

  • @spetro71189
    @spetro71189 5 ปีที่แล้ว +1

    you mention that the eosinophilic cytoplasm is something you look for. I was taught that if the dyskeratosis is primarily eosinophilic to think of Hailey Hailey. I know HH is much for acantholytic and diffuse, but would you agree with eosinophilic cytoplasms as a more specific sign for HH vs Grovers?

    • @JMGardnerMD
      @JMGardnerMD  5 ปีที่แล้ว +1

      Both diseases have eosinophilic cytoplasm. Agree that it is often more prominent in HH but not sure that is a specific or reliable finding on its own. HH supposedly has acantholysis with little or no true dyskeratosis (ie - no corps ronds or grains). Although I’ve seen cases of HH that had dyskeratosis. Clinical is most important way to distinguish as you said.

  • @iamnotafraid100
    @iamnotafraid100 5 ปีที่แล้ว +1

    Thank you 😀

  • @Pathologymadesimple
    @Pathologymadesimple 5 ปีที่แล้ว +1

    Hey Doc awesome video
    Keep it up😍

  • @RajKumar-tq6ho
    @RajKumar-tq6ho 5 ปีที่แล้ว +1

    Thank you sir...👌

  • @chaturakasimsetty6871
    @chaturakasimsetty6871 4 ปีที่แล้ว

    very explanatory!!!

  • @mohitrajpal266
    @mohitrajpal266 5 ปีที่แล้ว +1

    Thanku Sir

  • @nosondre
    @nosondre 2 ปีที่แล้ว

    I don’t have a microscope. What does the skin look like with the naked eye?

  • @UsamaIdrees-hl3sj
    @UsamaIdrees-hl3sj 4 ปีที่แล้ว

    Any indian or pakistani...What do we call this grovers disease in urdu or punjabi..

  • @jackt9535
    @jackt9535 3 ปีที่แล้ว

    This video is not exactly "papular"... "popular" would be more accurate :)