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Sir how antidopaminergic drugs cause dystonia?
The 1st generation neuroleptics preferentially block the D2 receptors (indirect pathway) so that there is more D1 (direct pathway) activation. This imbalance leads to tardive dyskinesia/dystonia. It's complicated, but I think that's the basic idea.
Sir how antidopaminergic drugs cause dystonia?
The 1st generation neuroleptics preferentially block the D2 receptors (indirect pathway) so that there is more D1 (direct pathway) activation. This imbalance leads to tardive dyskinesia/dystonia. It's complicated, but I think that's the basic idea.