Hi Ivor, An excellent presentation by two extremely logical and compassionate men who will change the trajectory of heart disease. I have a question in regards to my situation. I have reduced my CAC score by 100 points, down to 335 from 435, by doing time restricted feeding and keto. I basically eat OMAD with a snack before dinner. Fasting from 18-20 hours per day. I feel that I am one of those lean hyper responders that you speak of in your discussion. I am almost 60 years old, my lean BF % of 7, 155 pounds at 5’9”, weight train 5 days per week and sprint and walk a couple of times per week as well. My LDL is 173, HDL 94, triglycerides 63. Total cholesterol 283, but all ratios are excellent. I have noticed however, my fasting glucose has been increasing. I used to be between 85-95, now when I check it it is between 110-118. Am I becoming insulin resistant by eating a higher fat low carb diet for over a year now, and should I be concerned. I am feeling great and alert and stronger than ever. What is your take on all of this? I appreciate your time in advance for your thoughts on this. Oh, I had my fasting insulin tested last year and it was a 3.0. I have scheduled some more blood work and should have results in a few days. Thanks again.
Thanks for your prompt feedback Ivor. I so appreciate your help on this. It means a great deal to me. Thanks again for all that you do to help people like me trying our utmost to beat this disease.
Hey Brian, some studies are suggesting the body intentionally becomes insulin resistance when eating ultra low carb so as to intentionally spare glucose in the blood. It might not be pathological at all. It's worth doing some research on.
Brian Shultes just a thought, OCCASIONALLY, cycle out of ketosis. Maybe once every 10 days. I believe we need to eat like our ancestors. Which included an occasional high carb day. I doubt very much they walked right by berries and/or fruit cause “that wanted to stay in ketosis”. They would have gorged on them. Also, this teaches your body on how to switch between fuel sources.
This is pure gold. As a 57 yr old lean mass hyper-responder, it puts my mind at rest, even though my GP doesn't get it. Trigs/HDL = 0.5, but all my GP is interested in is the LDL.
...mine are at 0.236 with LDL close to 4 but my Doctor follows Dr Ali and so "he knows"; never mentions Statins during consultation and I have not exceeded 90g of carbs in a day since 2010.
I was on Lipitor and Repatha and cholesterols were very low. Doctors were satisfied and I was miserable. Low energy, forgetfulness and getting heavier by 5-20 per year over 5 years. Stopped taking the cholesterol drugs about a month ago because I felt so bad and within several weeks felt better. I happened on keto and IF videos and started absorbing the information. One month after eliminating sugar, the most carbs I can avoid and an 18-6 to 23 fasting schedule I've dropped 22 lbs, 42 to 38 pants. Last week my GP didn't have a problem with dropping the stating and Repatha but suggested taking another med which I declined. Cholesterol had already jumped up but I don't care and this video has reinforced my decision. Thank you Dr. Nadir!
Nadir is one of the great ones, while being extremely humble and cognizant of the need to adjust his assumptions as new evidence comes in. And Ivor is an effective popularizer, which every discipline needs.
I love the work of these two amazing experts! Your pace of delivery was at such a moderate speed that I was able to understand so much more than if the delivery had been at a fast pace. Thank you! Though you are both so full of knowledge and expertise in your areas, there is a compassion for the human condition that shines through your faces and your words. Bless you both!
I love that TH-cam lets you adjust the playback speed. I get impatient watching very long videos, but I put this one at 2x speed and it flew along at a pace I could tolerate, whilst still comprehending. I'm mentioning this because you can also adjust the playback speed down as low as half speed if you find some videos are moving too fast to follow. Maybe you know this already, but just in case it helps you.
Thank you, thank you....great conversation. Can’t express how grateful I am for all the information coming from both of you and others. I’ve learned so much, and changed my thought process on health, nutrition, ways of eating. It feels wonderful. With all your information, you’re creating a sense of ownership , over one’s life. Please, never worry about getting too, “Geeky”. I’d like to think I’ve become a better student,, (though, at first I had to listen, over and over, for it to sink in). Please know, we, the public are eager students, and greatly appreciate our teachers. Keep up the excellent work.
Ivor, thank you, I will donate to you next paycheck. Audio/video, 4k quality! You/Dr ali have been sent from God 🙏! I got my wife/parents CAC exams/Scores because of your youtube video! Thanks and keep up the good work! What an excellent interview!
Excellent discussion! Loved it! So nice to hear from a cardiologist who can speak to experience with patients and personal experience. Thank you Dr. Ali and Ivor for keeping it relevant and informative!
Thank you so much, Ivor !! ... I appreciate and respect Dr. Nadir Ali for his honesty and telling people the truth about cholesterol instead of the lies we hear from the establishment and the big pharmaceutical companies who have a lot of money to lose if people get healthy.... Thank you soooo much !!!
Such an excellent, balanced and reasonable discussion with nothing to prove other than measurable evidence. Where there’s an hypothesis or speculation it’s stated clearly as exactly that. No fudging or obfuscation. Thank you for sharing this reassurance that I’ve no need to give in to pressure to return to statins - which left me severely damaged. Thanks again
The only way to health is take full ownership and responsibility for your own health. You choose whether or not to stop eating crap foods and all sugars. You choose to eat only a whole food (including meat) diet. Your doctor can do very little, if anything, for your health. They are only useful for catastrophic problems and interventions.
The honesty is good here. I like the root cause approach. It could be unavoidable since recent trends with good results are now out in the public. I appreciate both of you being brave enough to look at the new and not just accept the old.
Good Evening , This is so refreshing to hear interventional cardiologist discussing the pathophysiology of lipids and there vehicles , and the paradoxical roles between high cholesterol and low carb . I am a clinical pharmacist and a biochemist and have long known about this paradox , and I have instructed patients to also do a low carb , keto based diet to lose weight , decrease inflammation, and protect there cardiovascular system . I also practice this , and have seen dramatic results with these patients and myself . Bravo for not following the mainstream cardiologist school of thought , and actually cure your patients or slow down dramatically the disease progression . Excellent point about why does the body produce all these lipids , instead of just relying on old data and old cholesterol theory which those of us that have done the research is outdated and false . Excellent point on lifestyle , nutrition , exercise these are the cornerstones to health and longevity . Nutrition is key , to quote hippocrates “ nutrition is thy medicine , and medicine is thy food
Thank you both , maybe people will become more aware and take more control of there health and listen to real science instead of all the pharmaceutical commercials which bombard us all everyday Dr Dave
Got my labs back from our bi yearly health fair, 25hydroxy D up from 41 to 134, just in time for coronavirus. Thanks for all your great videos, I like this heart doctor. 20000 ius of D3 per day, cutting back to 10,000iu and K2 to reverse my CAC score of 1072. Thanks for your time and great advice
Martin from Sea City Do not take K2 if you have stable plaque in your arteries. Calcified plaque is more stable than fatty plaque. Over 5,000 IU’s of vitamin D3 daily can cause kidney damage. Stay well.
Thank you for the information. I am 85, BMI 23,5.I swim 30-35 km a month in open water, I ride a bike 100 km. Low-density cholesterol is close to the extreme border zone, as is total cholesterol The blood test does not show any inflammation, the ratio of triglycerides to "good" cholesterol is one to one. Based on your reasoning, I throw away statins, which I took in a disciplined manner at the direction of a doctor (not an athlete:-)) I do it fist of all because l felt after two months unknown for me before lost of memory. Once more thank you.
two of my favorites Dr. Ali and Ivor thank you thank you for all you have done and continue to do. I am a LMHR and all my markers are excellent and my LDL-C and LDL-P continue to go up. HDL high and trigs in the toilet :) I have taken care of the root causes no more prehypertension or prediabetes, my CAC = 0 . Eating keto/low carb and focusing on protein has resulted in a stronger, leaner me with tons of energy, (working on pull ups and doing P:E diet thanks to Ted Niaman) My blood glucose response to non starchy carbs is now excellent I can safely eat more sweet potatoes and other tubers. With Covid 19 I'm going to leave my LDL where it is in hopes that my immune system is ready. Stay safe everyone and KETO ON!
55:53 “The power of an intervention to improve all of these significant variables (overweight, pre-diabetes, hypertension) in one individual is so high. So my point that I’m trying to make is that if a treatment works, you don’t need twenty-eight thousand patients to show a difference in outcome….If a pharmaceutical intervention needs 30,000 patients to show a half a percent difference in an all-cause mortality outcome, they should not even do that clinical trial, because it could just be noise." Love it!
My keto-type eating plan working very well thank you. Lots of fish and meat and other good fats like avocado and olive oil, eggs. I eat a lot of greens (mixed salads), and have cut my fruit intake quite significantly. I'm 65, and have been on this plan now for about 18 months.
An absolute must watch and listen. Most cardiologists in South Africa seem to pro-statin and anti-higher LDL. And the CAC test is hard ever used; I had all my days to get a CAC test done in December 2019. Even the dieticians don't have the facts.
patient with poorly controlled diabetes have high LDL-TG and once their sugar levels decrease, LDL-TG decreases and LDL-C increases. In other words, when LDL-TG is high, LDL particle is oxidized easier and it becomes small, dense and more atherogenic. When LDL-TG is low, LDL-C increases and the LDL particle is fluffy and less atherogenic.
I don't know if I'm a hyper Responder but my ldl went up from 93 to 153 on a low carb diet. I also do an 18/6 eating plan. My cardiologist wanted me to get off the diet. My trigs were 49 and my HDl 66. My weight went from 148 to 136 at five foot 7and a half. I went from lean to really lean. He put me on a statin for a short time but I couldn't tolerate them so i stopped. I suggested another calcium score. my score 5 years ago was 28. the score came back at 14. My Dad had his first heart attack at 51. I just turned 60 and have had no events. Hypertension also runs in the family dad was put on meds at 22 in the service me at 28. at one point i was on 20mg in 30's and 40's but i did way in the high 150's with a gut. now at age 60 i'm on 5mg and my weight today was 134.
Excellent! My husband had his heart scan. No complaints, he felt good, he fasts and is 30 days carnivore and 2 months keto..... Shazam!!!! His # was 2000...... he will be seeing a Dr this week. Funny thing is the Dr he will be seeing we haven't seen before. My husband had the clinic send him the results. He emailed my husband right away and asked him to look up videos my Ivor!!!! Wow, I think we picked an ok Dr. But...... what can he do for now? What questions should we ask or testing he should have!!!! Thank you so much! Love you both and I feel blessed to have always been digging for health truths!!!!
Great stuff Carol the key is to take the correct actions - I quite frankly amazed at how many random doctors around the world are recommending the CAC scan and my videos - make sure to share www.IHDA.ie so that others can benefit too! Four cardiologists discuss response to high score here - note 3 vid links in tweet, plus another discussion linked with Dr. Arthur Agatson- 4 in total twitter.com/FatEmperor/status/1239512440863371265?s=20
K2 MK7, plus vitamin D3. I take Koncentrated K. Ivor had the K guy on last year. I'm 73, pre-diabetic two years ago, but my trigs and cholesterol have always been low. Just had the scan, it was 6 in one artery, 0 in the other three.
Four cardiologists discuss response to high score here - note 3 vid links in tweet, plus another discussion linked with Dr. Arthur Agatson- 4 in total - best, ivor twitter.com/FatEmperor/status/1239512440863371265?s=20
@@IvorCumminsScience have had 5 heart bypasses I followed esselstyns ornish and mc dougall life style could not walk on the cooled in 3 months running 5 kin 3 month between seeing my doctor hospital appointments and finally my surgeon the week before the hope he was not happy at first but when I told him I was off al 10 meds and a symptomatic he said there he would not have the op pressing on a year or so later I got divorced went on a drinking and eating crap the angina came back my mental health suffered and so I was back to see my surgeon had the OP was in a bad way for a while but went and done more research found the likes of ivor and other fantastic low carb doctors and professors I am on low carb dont take meds diabetes gone again feel Brill started NHS 5k run using weights could not life 20 kg now lifting 60kg People have got to listen to the likes of ivor it saves lives God bless good luck by the way the low carb is far easier than vegan lifestyle cut out the sugar veg oils all processed foods like proof Robert lustig says and prof Tim noakes the world has to wake up by the way 3 months after the op my surgeon that my arteries where blocking up and there was nothing else's they could do that was 2 and a half years ago
I got a semi fit friend of mine started with keto. Her fitness improved markedly. She went to the doctor who ran a cholesterol test which found her LDL had gone "too high". She has since discontinued her keto diet. I'm thankful I've found keto, IF, CAC, etc. But I wish I would have found it 15 years ago.
Great video! I am keen on getting your advice wrt my recent lipids test results: TC 273 HDL 59 TG 58 LDL 208 TG/HDL Ratio 1.0 I take medication for hypertension and am suspected of having Familial Hypercholesterolemia (have corneal arcus, so it seems). Quit Statins 3 months ago. I do intermittent fasting 18:6 every day for 2 months. Have lost about 10kg. BMI of 20-21. Performed an Ankle Brachial Index DIY with a score of 1.5. I will really appreciate your advice Dr. Your lifesaving videos have served as my health guide these past months.
I love the point you made about how an engineer thinks vs an MD. If more MDs used thought processes like engineers, the trajectory of “sick-care” may actually change to true “health-care” as with functional medicine MDs.
I’ve chosen to ignore older 78 do Fitbit races 12 miles/ day resists weights upper arms. Feel great no joint problem. Some literature I read says older woman do better higher. I am a Carnivore OMAD. Also Fast to 1 GKI 72 hrs week.
I am so looking forward to learning more. My CAC was 755 April 2019; diagnosed T2D 11.9 Sep 2019; started intermittent fastiing under Jason Fung and many others....A1C is now 7.6.....yet my PCP doesn't give credit to the follwing results in lipids: TC 281/281/300; HDL 46/62/62; LDL 208/163/199 and hold on to this; triglycerides 133/281/194. S0 in 3 sets of sets since Oct 2019 to 28 May 2020...I have a 87 point drop in Tryg....my A1c realized 7.7 to 7.6 ..weight is down over 20 lbs.... ; haven't felt this great in over 25 years. And I am eating carnivore (Dr ken Berry and Dr Shawn Baker) and many more, keto/veg....and taking supplements that help insulin, etc. BP by the way was 120/80!! Next CAC is scheduled Sep 2020; will ask cardiologist to run C Peptide, C reactive and full lipid panel after review of CAC. I suspect it will drop from 755. I am a happy gal trying to improve her health and reverse type 2!
@Tony L I have worsened but Dr Nadir Ali doinf nuclear stress test in 2 weeks but till me to back off bacon and hwc and butter...eat more leaner meats and walk 5 times a week with green tea and being fasted. My a1c is 7 now...and not 1 year yet with way of life of fasting or ketovore. So I think one more year a1c will be below 5.7 and fat burning will increase
My Cardiologist is trying to get me to take injections to reduce my LDL from 260, but I have a HDL of 67 and a Triglyceride level of 76. I am Keto and and very lean about 6% body fat, I have a time restricted feeding window, Intermittent fasting and fast 16 hours per day and sometimes longer. I have worked out for many years seven seven days per week I believe myself to be a lean mass hyper responder. I was on about every Statin made and never felt worse in my life, they had tanked my cholesterol and were high fiveing each other, I took myself off of Statins. Through your videos I have learned to not be so focused on LDL, but eating healthy and fasting.
Hello Mr Cummins, can you comment on the recent MESA studies that showed that dense coronary artery calcium may be less dangerous than plaque with less density. And the your thouths on vit K2 for lowering calcium deposits? Do you think its beneficial to reduce it or does the calcium stabilize the plaque. Thank you. Haris
Great discussion. I'd like to hear Dr Ali speak on whether the type and number of LDL particles matter, i.e. LDL-P, LPa, ApoB; ApoA. If they do matter; what should those on lo carb or no carb who see these markers moving in a negative direction.
I have an appointment with Dr Nadir in early May. My CAC showed me in the 90 percentile. I had been seeing another cardiologist who gave me a nuclear stress test which costs $250.00. I thought I would know where the issue exactly is. Went for follow up and I was told that yes, I have blockage, but not known exactly where. So was given the option of invasive, thru an artery starting in the groin or non invasive with an IV involving dye and a CT scan. Also wants me to start taking bi weekly cholesterol shots because my LDL is 176. Time for Dr. Ali!
Also see four cardiologists discuss response to high-ish score here - note 2 links in tweet, plus another discussing linked - 4 in total: twitter.com/FatEmperor/status/1239512440863371265?s=20
Your view on Repatha I have been taking it for a year my ldl is around 70 dr wants it lower after watching this I think it is fine but my sugar has gone up to 150 watching my diet if sugar doesn’t come down I am thinking of taking to dr about stopping Repatha cause I know the sugar is worse than the cholesterol
So I had a CAC in mid July on my own just to check. My score was 575. Not good. Since that day I have been doing keto and intermittent fasting. I’m seeing a cardiologist on Friday. I have listened to and read a lot of your information. From my reading I didn’t think it was actually possible to reverse this score. Can you lower your CAC score?
These gentlemen are absolutely right my personal experience 2018 was given 20 milligrams of lovastatin supposedly to raise my hdl was a low of 37mgperdcl, Dr wanted at least 40 after 6 mo developed what he said was burcitis below my inner left knee which was very painful and created a limp while walking after steroid and cortisone injections was no help, sent me to a orthopedic specialist with same results and many injections, 6 mos later still limping, increased lovastatin to 40mg 3mos later left leg pain unbearable from knee to ankle, took me off statin pain disappeared within 72 hrs no more statin for me lost 40lbs in 18mos it took from march 2019 to June 2020 for legs to heal, that was my personal story, I was 72 then could barely walk today I can chase my grandkids around the yard I estimate I would have been in a wheelchair in 6 months
Great Video! Thank you Doctor and Ivor! Ivor... one question: You talked about a "get out" option for low cab for people whose LDL skyrockets doing low carb (myself). All my other blood markers improved. BUT- I am Apoe4. Since you have the Apoe4 gene what do you do? Do you do "Keto Lite" ?? Have you modified your Keto/Low carb? THANKS
Hey Jake I don't personally do anything but it's a personal choice - here is the general approach from an excerpt from our book - possibly useful for concerned ApoE4's drive.google.com/file/d/154zLw3a8DVE3B4ootykO-n-NlRmFgdXA/view?usp=sharing My interview with Dr. Stephen Gundry on ApoE4 out soon!
@@IvorCumminsScience Wow! Thank you for the reply and link Ivor!! I am inclined to stay the course but want to make a decision by looking at the data and also finding out what folks like yourself who I respect a lot do. That matters to me.
@@IvorCumminsScience Funny you should say that about cholesterol manipulation... I had my bloods done 40 hrs into a fast and my LDL jumped much higher up to 276.... that's a record for me. My personal best:) Dr. Nadir Ali mentioned LDL jumping up while fasting... that was all new to me.
@@IvorCumminsScience I can't wait to hear that!!! I watch all your vids, even the longer ones since they are full of great content and I always learn helpful things. Thanks for your good work man!
Thanks, Ivor and Dr. Ali. Could anyone here clarify a vague point for me? Dr. Kendrick says that LDL cannot pasa the endothelium, but I’ve also heard Ivor say that there are papers showing endocytosis of LDL through the artery walls. Those two statements appear contradictory. Could endocytosis be occurring in the vasa vasorum side instead of the main highway of the artery? Has LDL been actually observed to transcytose, or is it merely an inference that it takes place?
Yesterday my "home" taken bloods were 79 glucose( ketones 4.0), Triglycerides 74 but my Total cholesterol 381. I need to find out at least my HDL but am not going near a doctor with a figure of 381, I'm never taking statins...- I've just bought a better meter that would give me HDL/LDL/Total....could this high total cholesterol indicate familial hypercholesterolemia? Been keto 10 weeks with IF and a few prolonged fasts but almost zero carb bordering carnivore...been eating 4 whole eggs a day on this journey could this be raising cholesterol (I know it's not meant to??) I live in Scottish Highlands and getting this CAC CT scan done privately is a task (700 mile round trip to Manchester??) let alone asking the family doc/NHS.... BTW my blood pressure has fallen massively too now 110/59 with RHR of 48bpm...
Hi Ivor, An excellent presentation by two extremely logical and compassionate men who will change the trajectory of heart disease. I have a question in regards to my situation. I have reduced my CAC score by 100 points, down to 335 from 435, by doing time restricted feeding and keto. I basically eat OMAD with a snack before dinner. Fasting from 18-20 hours per day. I feel that I am one of those lean hyper responders that you speak of in your discussion. I am almost 60 years old, my lean BF % of 7, 155 pounds at 5’9”, weight train 5 days per week and sprint and walk a couple of times per week as well. My LDL is 173, HDL 94, triglycerides 63. Total cholesterol 283, but all ratios are excellent. I have noticed however, my fasting glucose has been increasing. I used to be between 85-95, now when I check it it is between 110-118. Am I becoming insulin resistant by eating a higher fat low carb diet for over a year now, and should I be concerned. I am feeling great and alert and stronger than ever. What is your take on all of this? I appreciate your time in advance for your thoughts on this. Oh, I had my fasting insulin tested last year and it was a 3.0. I have scheduled some more blood work and should have results in a few days. Thanks again.
Hey Brian great job - this glucose happens commonly - need use HOMA calculator not just glucose - target is to be below 1.2 , and you are
Thanks for your prompt feedback Ivor. I so appreciate your help on this. It means a great deal to me. Thanks again for all that you do to help people like me trying our utmost to beat this disease.
Hey Brian, some studies are suggesting the body intentionally becomes insulin resistance when eating ultra low carb so as to intentionally spare glucose in the blood. It might not be pathological at all. It's worth doing some research on.
Brian Shultes just a thought, OCCASIONALLY, cycle out of ketosis. Maybe once every 10 days. I believe we need to eat like our ancestors. Which included an occasional high carb day. I doubt very much they walked right by berries and/or fruit cause “that wanted to stay in ketosis”. They would have gorged on them. Also, this teaches your body on how to switch between fuel sources.
thejollysatan thanks for your feedback my friend
Thank you both for having the courage to show us all the REAL path , you are saving thousands of us from a horrible life.
This is pure gold. As a 57 yr old lean mass hyper-responder, it puts my mind at rest, even though my GP doesn't get it. Trigs/HDL = 0.5, but all my GP is interested in is the LDL.
...mine are at 0.236 with LDL close to 4 but my Doctor follows Dr Ali and so "he knows"; never mentions Statins during consultation and I have not exceeded 90g of carbs in a day since 2010.
I was on Lipitor and Repatha and cholesterols were very low. Doctors were satisfied and I was miserable. Low energy, forgetfulness and getting heavier by 5-20 per year over 5 years. Stopped taking the cholesterol drugs about a month ago because I felt so bad and within several weeks felt better. I happened on keto and IF videos and started absorbing the information. One month after eliminating sugar, the most carbs I can avoid and an 18-6 to 23 fasting schedule I've dropped 22 lbs, 42 to 38 pants. Last week my GP didn't have a problem with dropping the stating and Repatha but suggested taking another med which I declined. Cholesterol had already jumped up but I don't care and this video has reinforced my decision. Thank you Dr. Nadir!
Nadir is one of the great ones, while being extremely humble and cognizant of the need to adjust his assumptions as new evidence comes in. And Ivor is an effective popularizer, which every discipline needs.
I love the work of these two amazing experts! Your pace of delivery was at such a moderate speed that I was able to understand so much more than if the delivery had been at a fast pace. Thank you! Though you are both so full of knowledge and expertise in your areas, there is a compassion for the human condition that shines through your faces and your words. Bless you both!
I love that TH-cam lets you adjust the playback speed. I get impatient watching very long videos, but I put this one at 2x speed and it flew along at a pace I could tolerate, whilst still comprehending.
I'm mentioning this because you can also adjust the playback speed down as low as half speed if you find some videos are moving too fast to follow. Maybe you know this already, but just in case it helps you.
@@andoletube Didn’t know that. Thanks for letting us know.
Two great men with great common sense , unlike our medical system thank you to both of you .
Thank you, thank you....great conversation. Can’t express how grateful I am for all the information coming from both of you and others. I’ve learned so much, and changed my thought process on health, nutrition, ways of eating. It feels wonderful. With all your information, you’re creating a sense of ownership , over one’s life. Please, never worry about getting too, “Geeky”. I’d like to think I’ve become a better student,, (though, at first I had to listen, over and over, for it to sink in). Please know, we, the public are eager students, and greatly appreciate our teachers. Keep up the excellent work.
Ivor, thank you, I will donate to you next paycheck. Audio/video, 4k quality! You/Dr ali have been sent from God 🙏! I got my wife/parents CAC exams/Scores because of your youtube video! Thanks and keep up the good work! What an excellent interview!
Excellent discussion! Loved it! So nice to hear from a cardiologist who can speak to experience with patients and personal experience. Thank you Dr. Ali and Ivor for keeping it relevant and informative!
Thank you so much, Ivor !! ... I appreciate and respect Dr. Nadir Ali for his honesty and telling people the truth about cholesterol instead of the lies we hear from the establishment and the big pharmaceutical companies who have a lot of money to lose if people get healthy.... Thank you soooo much !!!
Wow! That was an incredible interview. 💯
Absolutely worthy of a re-watch.
What an incredible man. Very easy to follow and understand.
I shall be viewing everything of his I can find. Very impressed.
Such a polite knowledgeable man...how refreshing! Thank you
Such an excellent, balanced and reasonable discussion with nothing to prove other than measurable evidence. Where there’s an hypothesis or speculation it’s stated clearly as exactly that. No fudging or obfuscation.
Thank you for sharing this reassurance that I’ve no need to give in to pressure to return to statins - which left me severely damaged. Thanks again
Another great show Ivor. Dr Ali is terrific. The intersection of theory and practice.
If I had a doctor like this, I might go see him once in a while. My doctor is a waste of time. I'm going to go get a cac test and pay for it myself.
yep i just sacked my family dr recently. He is completely hopeless
The only way to health is take full ownership and responsibility for your own health.
You choose whether or not to stop eating crap foods and all sugars.
You choose to eat only a whole food (including meat) diet.
Your doctor can do very little, if anything, for your health. They are only useful for catastrophic problems and interventions.
@chekyerego, I just did. Wasn't that expensive either. My score totally contradicts the lipid hypothesis.
Ugh I know this very issue all to well!! My doctor had literally roll his eyes twice at me while I tried to explain my anxiety...
The honesty is good here. I like the root cause approach. It could be unavoidable since recent trends with good results are now out in the public. I appreciate both of you being brave enough to look at the new and not just accept the old.
This level of professionalism and integrity restores my hope for the future of medicine.
Good Evening ,
This is so refreshing to hear interventional cardiologist discussing the pathophysiology of lipids and there vehicles , and the paradoxical roles between high cholesterol and low carb . I am a clinical pharmacist and a biochemist and have long known about this paradox , and I have instructed patients to also do a low carb , keto based diet to lose weight , decrease inflammation, and protect there cardiovascular system . I also practice this , and have seen dramatic results with these patients and myself . Bravo for not following the mainstream cardiologist school of thought , and actually cure your patients or slow down dramatically the disease progression . Excellent point about why does the body produce all these lipids , instead of just relying on old data and old cholesterol theory which those of us that have done the research is outdated and false . Excellent point on lifestyle , nutrition , exercise these are the cornerstones to health and longevity . Nutrition is key ,
to quote hippocrates “ nutrition is thy medicine , and medicine is thy food
Thank you both , maybe people will become more aware and take more control of there health and listen to real science instead of all the pharmaceutical commercials which bombard us all everyday
Dr Dave
Got my labs back from our bi yearly health fair, 25hydroxy D up from 41 to 134, just in time for coronavirus. Thanks for all your great videos, I like this heart doctor. 20000 ius of D3 per day, cutting back to 10,000iu and K2 to reverse my CAC score of 1072. Thanks for your time and great advice
Martin from Sea City
Do not take K2 if you have stable plaque in your arteries. Calcified plaque is more stable than fatty plaque.
Over 5,000 IU’s of vitamin D3 daily can cause kidney damage.
Stay well.
Consider adding magnesium.
Thank you for the information. I am 85, BMI 23,5.I swim 30-35 km a month in open water, I ride a bike 100 km. Low-density cholesterol is close to the extreme border zone, as is total cholesterol The blood test does not show any inflammation, the ratio of triglycerides to "good" cholesterol is one to one. Based on your reasoning, I throw away statins, which I took in a disciplined manner at the direction of a doctor (not an athlete:-)) I do it fist of all because l felt after two months unknown for me before lost of memory. Once more thank you.
what an incredibly informative and interesting discussion. This has to be my favourite podcast of the year so far. Thank you both
two of my favorites Dr. Ali and Ivor thank you thank you for all you have done and continue to do. I am a LMHR and all my markers are excellent and my LDL-C and LDL-P continue to go up. HDL high and trigs in the toilet :)
I have taken care of the root causes no more prehypertension or prediabetes, my CAC = 0 . Eating keto/low carb and focusing on protein has resulted in a stronger, leaner me with tons of energy, (working on pull ups and doing P:E diet thanks to Ted Niaman) My blood glucose response to non starchy carbs is now excellent I can safely eat more sweet potatoes and other tubers.
With Covid 19 I'm going to leave my LDL where it is in hopes that my immune system is ready. Stay safe everyone and KETO ON!
@@BelCantoLari Lean Mass Hyperresponder. Someone who's LDL rises on keto
Remember, nobody knows if lmhr is healthy. It's still a theory and observation. I am one too. Nobody knows what to do with us.
55:53 “The power of an intervention to improve all of these significant variables (overweight, pre-diabetes, hypertension) in one individual is so high. So my point that I’m trying to make is that if a treatment works, you don’t need twenty-eight thousand patients to show a difference in outcome….If a pharmaceutical intervention needs 30,000 patients to show a half a percent difference in an all-cause mortality outcome, they should not even do that clinical trial, because it could just be noise." Love it!
Brilliant discussion. Dr Ali is impressive
Thanks Ivory for a very logical and informative presentation and also thanks for the genius Dr.Nadir
Killer interview. 2 really smart guys going deep into important stuff.
My keto-type eating plan working very well thank you. Lots of fish and meat and other good fats like avocado and olive oil, eggs. I eat a lot of greens (mixed salads), and have cut my fruit intake quite significantly. I'm 65, and have been on this plan now for about 18 months.
"It's not that LDL is the problem, it's just that LDL is connected to the problem." -- Ivor Cummins @ 36:20
Thank you Ivor. This interview was great you just introduced me to another great knowledgeable person worth listening to.
An absolute must watch and listen. Most cardiologists in South Africa seem to pro-statin and anti-higher LDL. And the CAC test is hard ever used; I had all my days to get a CAC test done in December 2019. Even the dieticians don't have the facts.
So interesting I could listen to them all...day....long....
I just had a goose bump listening to your podcasts! Thank you Ivor and Dr. Nadir Ali for super informative discussion !
Thanks for sharing among those who have this gift from God to help humanity. God bless you doctor.
patient with poorly controlled diabetes have high LDL-TG and once their sugar levels decrease, LDL-TG decreases and LDL-C increases. In other words, when LDL-TG is high, LDL particle is oxidized easier and it becomes small, dense and more atherogenic. When LDL-TG is low, LDL-C increases and the LDL particle is fluffy and less atherogenic.
Thank you both for all your work spreading the word!
I don't know if I'm a hyper Responder but my ldl went up from 93 to 153 on a low carb diet. I also do an 18/6 eating plan. My cardiologist wanted me to get off the diet. My trigs were 49 and my HDl 66. My weight went from 148 to 136 at five foot 7and a half. I went from lean to really lean. He put me on a statin for a short time but I couldn't tolerate them so i stopped. I suggested another calcium score. my score 5 years ago was 28. the score came back at 14. My Dad had his first heart attack at 51. I just turned 60 and have had no events. Hypertension also runs in the family dad was put on meds at 22 in the service me at 28. at one point i was on 20mg in 30's and 40's but i did way in the high 150's with a gut. now at age 60 i'm on 5mg and my weight today was 134.
just shared this Great Conversation on a Facebook statin site.
Dr Nadir Ali is awesome!!
Ivor and Dr. Nadir Ali were fascinating. I'm not sure how to apply all of their suggestions, so I will have to watch multiple times, I think.
Dr. Ali is the Greatest. Kudos.
Excellent! My husband had his heart scan. No complaints, he felt good, he fasts and is 30 days carnivore and 2 months keto..... Shazam!!!! His # was 2000...... he will be seeing a Dr this week. Funny thing is the Dr he will be seeing we haven't seen before. My husband had the clinic send him the results. He emailed my husband right away and asked him to look up videos my Ivor!!!! Wow, I think we picked an ok Dr. But...... what can he do for now? What questions should we ask or testing he should have!!!! Thank you so much! Love you both and I feel blessed to have always been digging for health truths!!!!
Great stuff Carol the key is to take the correct actions - I quite frankly amazed at how many random doctors around the world are recommending the CAC scan and my videos - make sure to share www.IHDA.ie so that others can benefit too! Four cardiologists discuss response to high score here - note 3 vid links in tweet, plus another discussion linked with Dr. Arthur Agatson- 4 in total twitter.com/FatEmperor/status/1239512440863371265?s=20
K2 MK7, plus vitamin D3. I take Koncentrated K. Ivor had the K guy on last year. I'm 73, pre-diabetic two years ago, but my trigs and cholesterol have always been low. Just had the scan, it was 6 in one artery, 0 in the other three.
Four cardiologists discuss response to high score here - note 3 vid links in tweet, plus another discussion linked with Dr. Arthur Agatson- 4 in total - best, ivor twitter.com/FatEmperor/status/1239512440863371265?s=20
@@IvorCumminsScience have had 5 heart bypasses I followed esselstyns ornish and mc dougall life style could not walk on the cooled in 3 months running 5 kin 3 month between seeing my doctor hospital appointments and finally my surgeon the week before the hope he was not happy at first but when I told him I was off al 10 meds and a symptomatic he said there he would not have the op pressing on a year or so later I got divorced went on a drinking and eating crap the angina came back my mental health suffered and so I was back to see my surgeon had the OP was in a bad way for a while but went and done more research found the likes of ivor and other fantastic low carb doctors and professors I am on low carb dont take meds diabetes gone again feel Brill started NHS 5k run using weights could not life 20 kg now lifting 60kg
People have got to listen to the likes of ivor it saves lives God bless good luck by the way the low carb is far easier than vegan lifestyle cut out the sugar veg oils all processed foods like proof Robert lustig says and prof Tim noakes the world has to wake up by the way 3 months after the op my surgeon that my arteries where blocking up and there was nothing else's they could do that was 2 and a half years ago
@Hugh Janus mechanistically impossible. CAC evolves over decades. even diseased 20y/o usually won't have calcium
Fantastic Dr Nadir . Your speeches make sense and are live changing!
I got a semi fit friend of mine started with keto. Her fitness improved markedly. She went to the doctor who ran a cholesterol test which found her LDL had gone "too high". She has since discontinued her keto diet.
I'm thankful I've found keto, IF, CAC, etc. But I wish I would have found it 15 years ago.
Get her to get a CAC score, then she can see that she doesn't have to worry about her LDL!
Wow what an incredible interview. So educational and
Informative. Thank you
You’re hosting my fav cardiologist! Keto and IF!!!!!!
Great video!
I am keen on getting your advice wrt my recent lipids test results:
TC 273
HDL 59
TG 58
LDL 208
TG/HDL Ratio 1.0
I take medication for hypertension and am suspected of having Familial Hypercholesterolemia (have corneal arcus, so it seems). Quit Statins 3 months ago. I do intermittent fasting 18:6 every day for 2 months. Have lost about 10kg. BMI of 20-21. Performed an Ankle Brachial Index DIY with a score of 1.5.
I will really appreciate your advice Dr. Your lifesaving videos have served as my health guide these past months.
I love the point you made about how an engineer thinks vs an MD. If more MDs used thought processes like engineers, the trajectory of “sick-care” may actually change to true “health-care” as with functional medicine MDs.
Brilliant, loved this talk.
Absolutely love both of you!
This was an excellent discussion!
Listening to such an informative discussion is so uplifting. 😄
This is pure Gold ,2 of the best 👌
Excellent discussion and points raised below, & you've done it again IVOR first class video, not sure how I missed this one after 3 months.
Superb clarity!Great job by two dedicated doctors.
We pray that Dr Nadir Mir Ali and Mr Ivor Cummins be invited by our Cardiologist in the Philippines
Excellent video, Echoes my experience switching from a sad American diet and vegetarian diets to a more low carb animal based diet with healthy fats.
Thank you very much for the wonderful videos
This session is so good! I'm learning so much. Thank you so much for this information. The whole world 🌎 needs to know this.
Wonderful and informative discussion. Thank you!
Thank you for these wonderful insights which normal practitioner and big Pharma would never do!
Interesting, thanks Ivor. It’s nice to have an engineer looking at these problems.
Thanks to both of you! An empowering and inspiring talk!
Ivor is a great listener!
I’ve chosen to ignore older 78 do Fitbit races 12 miles/ day resists weights upper arms. Feel great no joint problem. Some literature I read says older woman do better higher. I am a Carnivore OMAD. Also Fast to 1 GKI 72 hrs week.
Do ferritin levels matter?
Is slightly lower better?
I am so looking forward to learning more. My CAC was 755 April 2019; diagnosed T2D 11.9 Sep 2019; started intermittent fastiing under Jason Fung and many others....A1C is now 7.6.....yet my PCP doesn't give credit to the follwing results in lipids: TC 281/281/300; HDL 46/62/62; LDL 208/163/199 and hold on to this; triglycerides 133/281/194. S0 in 3 sets of sets since Oct 2019 to 28 May 2020...I have a 87 point drop in Tryg....my A1c realized 7.7 to 7.6 ..weight is down over 20 lbs.... ; haven't felt this great in over 25 years. And I am eating carnivore (Dr ken Berry and Dr Shawn Baker) and many more, keto/veg....and taking supplements that help insulin, etc. BP by the way was 120/80!! Next CAC is scheduled Sep 2020; will ask cardiologist to run C Peptide, C reactive and full lipid panel after review of CAC. I suspect it will drop from 755. I am a happy gal trying to improve her health and reverse type 2!
@@BelCantoLari It's not good..it doubled! Going to get a PET scan on heart in 3 weeks with Dr Ali
Kim P you can also try using vitamin K2-7 and D3 as a way to reduce calcium score
@Tony L I have worsened but Dr Nadir Ali doinf nuclear stress test in 2 weeks but till me to back off bacon and hwc and butter...eat more leaner meats and walk 5 times a week with green tea and being fasted. My a1c is 7 now...and not 1 year yet with way of life of fasting or ketovore. So I think one more year a1c will be below 5.7 and fat burning will increase
Not good...k2 m7 and d3 didn't reduce the plaque but I did increase it double. Working with cardiologist Dr ali in keto world as to why.
@@BelCantoLari not great at all it doubled
Thank you, Dr's. I'm struggling with this very thing!
Outstanding information! Great stuff, as always Ivor. I’m learning so much! Thanks.
Thank you for yet another excellent informative video!
Brilliant interview. Such good information from Dr Ali. Oh how I wish I was in Houston and could visit his clinic!
Brilliant! Thank you both!
Yes indeed spread the word.
Very informative...
Thanks really Dear
My Cardiologist is trying to get me to take injections to reduce my LDL from 260, but I have a HDL of 67 and a Triglyceride level of 76. I am Keto and and very lean about 6% body fat, I have a time restricted feeding window, Intermittent fasting and fast 16 hours per day and sometimes longer. I have worked out for many years seven seven days per week I believe myself to be a lean mass hyper responder. I was on about every Statin made and never felt worse in my life, they had tanked my cholesterol and were high fiveing each other, I took myself off of Statins. Through your videos I have learned to not be so focused on LDL, but eating healthy and fasting.
Hello Mr Cummins, can you comment on the recent MESA studies that showed that dense coronary artery calcium may be less dangerous than plaque with less density. And the your thouths on vit K2 for lowering calcium deposits? Do you think its beneficial to reduce it or does the calcium stabilize the plaque.
Thank you.
Haris
Great information thank you for all that you share
Great discussion. I'd like to hear Dr Ali speak on whether the type and number of LDL particles matter, i.e. LDL-P, LPa, ApoB; ApoA. If they do matter; what should those on lo carb or no carb who see these markers moving in a negative direction.
I'd like to hear that as well.
I have an appointment with Dr Nadir in early May. My CAC showed me in the 90 percentile. I had been seeing another cardiologist who gave me a nuclear stress test which costs $250.00. I thought I would know where the issue exactly is. Went for follow up and I was told that yes, I have blockage, but not known exactly where. So was given the option of invasive, thru an artery starting in the groin or non invasive with an IV involving dye and a CT scan. Also wants me to start taking bi weekly cholesterol shots because my LDL is 176. Time for Dr. Ali!
Also see four cardiologists discuss response to high-ish score here - note 2 links in tweet, plus another discussing linked - 4 in total: twitter.com/FatEmperor/status/1239512440863371265?s=20
thank you for this informative video, you 2 are amazing
Very informative, Excellent message to everyone!!
God bless you both!
Slan
Your view on Repatha I have been taking it for a year my ldl is around 70 dr wants it lower after watching this I think it is fine but my sugar has gone up to 150 watching my diet if sugar doesn’t come down I am thinking of taking to dr about stopping Repatha cause I know the sugar is worse than the cholesterol
Excellent Discussion -- thanks much.
Awesome....What is frightening here is that I am 20 minutes and neither person has mentioned MGP or vitamin K2.
What is MGP
Brilliant!!
So I had a CAC in mid July on my own just to check. My score was 575. Not good. Since that day I have been doing keto and intermittent fasting. I’m seeing a cardiologist on Friday. I have listened to and read a lot of your information. From my reading I didn’t think it was actually possible to reverse this score. Can you lower your CAC score?
Cynthia Roseberry : check out Ford Brewer videos on TH-cam
any updates
These gentlemen are absolutely right my personal experience 2018 was given 20 milligrams of lovastatin supposedly to raise my hdl was a low of 37mgperdcl, Dr wanted at least 40 after 6 mo developed what he said was burcitis below my inner left knee which was very painful and created a limp while walking after steroid and cortisone injections was no help, sent me to a orthopedic specialist with same results and many injections, 6 mos later still limping, increased lovastatin to 40mg 3mos later left leg pain unbearable from knee to ankle, took me off statin pain disappeared within 72 hrs no more statin for me lost 40lbs in 18mos it took from march 2019 to June 2020 for legs to heal, that was my personal story, I was 72 then could barely walk today I can chase my grandkids around the yard I estimate I would have been in a wheelchair in 6 months
If I am understanding, If you are not eliminating the excess cholesterol due to FH you may end up with more oxidized LDL in your blood stream?
What do you recommend to someone with cholesteroliol ldl 354?
Great... Thank you
Great Video! Thank you Doctor and Ivor!
Ivor... one question: You talked about a "get out" option for low cab for people whose LDL skyrockets doing low carb (myself). All my other blood markers improved. BUT- I am Apoe4. Since you have the Apoe4 gene what do you do? Do you do "Keto Lite" ?? Have you modified your Keto/Low carb?
THANKS
Hey Jake I don't personally do anything but it's a personal choice - here is the general approach from an excerpt from our book - possibly useful for concerned ApoE4's drive.google.com/file/d/154zLw3a8DVE3B4ootykO-n-NlRmFgdXA/view?usp=sharing
My interview with Dr. Stephen Gundry on ApoE4 out soon!
...also see www.cholesterolcode.com where LDL can be manipulated up and down with diet (big swings)
@@IvorCumminsScience Wow! Thank you for the reply and link Ivor!! I am inclined to stay the course but want to make a decision by looking at the data and also finding out what folks like yourself who I respect a lot do. That matters to me.
@@IvorCumminsScience Funny you should say that about cholesterol manipulation... I had my bloods done 40 hrs into a fast and my LDL jumped much higher up to 276.... that's a record for me. My personal best:) Dr. Nadir Ali mentioned LDL jumping up while fasting... that was all new to me.
@@IvorCumminsScience I can't wait to hear that!!! I watch all your vids, even the longer ones since they are full of great content and I always learn helpful things. Thanks for your good work man!
Thanks, Ivor and Dr. Ali.
Could anyone here clarify a vague point for me? Dr. Kendrick says that LDL cannot pasa the endothelium, but I’ve also heard Ivor say that there are papers showing endocytosis of LDL through the artery walls.
Those two statements appear contradictory.
Could endocytosis be occurring in the vasa vasorum side instead of the main highway of the artery? Has LDL been actually observed to transcytose, or is it merely an inference that it takes place?
I've wondered this too!
Help! Ivor, I can't find your donation link?
He says "I don't know why we are so in love with drug therapies" or words to that effect. Answer.....$$$
After watching a few of these vids I'm now eating carb free food only on it less then a week and my blood sugar levels have dropped from 9.8 to 5.4
My HBA1C for last 2 years is constant between 4.5 to 4.7 but my RBC is always low. Is my HBA1C low because of low RBC ?
My triglycerides are high and LDL high... CAC score is zero. Confused. 50 years old. On keto for 4 years! Dr's think I am about to die.
I have had stent installed in my heart. The doctor prescribed a statin drug for me to take for the rest of my life. Should i obey him ?
Yesterday my "home" taken bloods were 79 glucose( ketones 4.0), Triglycerides 74 but my Total cholesterol 381. I need to find out at least my HDL but am not going near a doctor with a figure of 381, I'm never taking statins...- I've just bought a better meter that would give me HDL/LDL/Total....could this high total cholesterol indicate familial hypercholesterolemia? Been keto 10 weeks with IF and a few prolonged fasts but almost zero carb bordering carnivore...been eating 4 whole eggs a day on this journey could this be raising cholesterol (I know it's not meant to??) I live in Scottish Highlands and getting this CAC CT scan done privately is a task (700 mile round trip to Manchester??) let alone asking the family doc/NHS.... BTW my blood pressure has fallen massively too now 110/59 with RHR of 48bpm...
www.cholesterolcode.com
@Abdel-Ilah BENAHMED why is this? Is it bad ? Nobody seems to have connected all or any of the cholesterol "dots"...