The topics are handled so keen that the viewers can again build their knowledge with these lectures as the basement.. Thanks for your passion for a sincere explanation ..
During this lock down days , we have online lectures , and your explanation is very helpful to understand our topics 🤗 and we want more pathology explanation
Sir in pathfinder book it is mentioned that enzyme with odd Roman no. After their name are type 1 and with even no. Are type 2, so which is the correct one?
DNA gyrase is Topoisomerase II acting as a swivel to induce negative supercoiling from positive. And topoisomerase IV is responsible for termination of DNA replication
Good morning sir I am ur old student when I met u in Bangalore there was only 4 students 3girls and a boy(me). I m missing u sir. I have a doubt that how dna polymerase distinguishes between dntps and ntps pls tell me sir
there are some aminoacids in the nucleotide binding pocket of dna pol(in the palm region of dna pol)called discriminator amino acids which helps to distinguish between dntp and ntps
I don't think that is correct... in the second part of the video the primer in the loop…when you imagine you straighten the loop out... than the primers in both chains will be in the same direction….or…leading strand is 5‘ (on the left) - 3´(on the right) so lagging strand is 3‘ (on the left) than on the end of the loop it should be 5‘ ....but primer on it starts also with 5‘…Still thanks for your videos, your teaching helps me a lot!
The topics are handled so keen that the viewers can again build their knowledge with these lectures as the basement.. Thanks for your passion for a sincere explanation ..
Thank you so much for appreciating my efforts
Oh my goodness, even class teachers can't explain like this. Thanku so much sir. YOU ARE GREAT
Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures. Please subscribe and share
Understanding concepts has never been easier. Thank you so much for making these important concepts so lucid.
You're welcome. Glad to hear that you're getting benefit from my lectures
Was trying to understand this for the past 3 days, and today only 17 mins and cleared the entire concept. Sir you are great.
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Nobody wants to stress...
Yes you are my Topoisomerase relese my stress during exam 👍👍
Yes. Indeed
Onek onek dhonyobad aapnak🙌✨
😊
Such a beautiful mechanism. Topoisomerase is the tailor of proteins
Yes it is
Excellent effort from shomu's biology.Thank you very much.Keep going
Hero means helper that's is shomo sir ❤️
Thank you
Sir i really understood this DNA topoisomerase .
Thnkx a lot of u sir 👏👏💐💐💐
From.........odisha
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Those ones who disliked this video must be jealous of shomu sir😂😂😂
You are just perfect teacher sir😊
Thank you so much for appreciating my efforts
During this lock down days , we have online lectures , and your explanation is very helpful to understand our topics 🤗 and we want more pathology explanation
Thank you so much for appreciating my efforts. Glad to hear that you're getting benefit from my lectures
Very simple and clear explanation. Thank you for making it simple :)
You're welcome. Glad to hear that you're getting benefit from my lectures
In teachers your are all in all sir. Thank you, it was very helpful.
You're welcome
Great explanation ,thank you.
You're welcome
Sir thank you very much, you are really a great teacher.
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A best mentor kindly share your notes of lecturer...
nice lecture ....and u make my concept clear during exam .......so tnq once again
Bro what's your educational qualifications can we know?
Really comprehensive explanation.
Msc. In Microbiology
R u doing PhD in microbiology 🙄
You are a very talented teacher my friend
Do you have a video on topoisomerase inhibitors.
It is very complete video,thanks.
I have one question.
Gyrase convert positive coil to negative?
Excellent 👌
Thank you
Sir, you are phenomenal, sir apki video ky ilawa, mujy kisi aur ka smjh hi nae ata.
Thank you so much for appreciating my efforts
Thank you very much your lectures were amazing and really helpful
I cannot find the separate videos of topoisomerase 1 and 2
Coming soon
Thank you shomu sir
What is the meaning of negative supercoiling?
Type I topoisomerase has 2 subfamilies typeIA and typeIB
Type II topo has 2 subfamilies typeIIA and type IIB
Darun bujhiyechho.
Thank you
Your videos are very helpful!!
+shop2012 thank you.
what a explanation i can't tell you that.But this video really help me out thank you sir .
Sir tqqq soo much your explanation ISS awesome it's easily understood tq for uploading sir
Thank you.Your videos are very helpfu
+naeem m-m you're welcome
i have a question. does topoisomerase work only on circular dna or it can work also on linear one? please reply
It can work also on linear one
Thank you.
Thank You So Much Sir.
You're welcome
No. Topoisomerase type IA comprises 3distinct classes and one of them is topoisomerase III
9:32 How I feel about my professor who originally made this such a confusing concept.
Lmao same fam
Hey, so the topoisomerase 1 only involved in the cccdna cellular process, right?
this is great, thank you!
You're welcome
Negative super coil fevour unwind the dna?
love your videos. You are so smart!!Thanks for your videos.
+nerd nerd thank you. Glad you liked my lecture
+nerd nerd thank u
Sir in pathfinder book it is mentioned that enzyme with odd Roman no. After their name are type 1 and with even no. Are type 2, so which is the correct one?
Yes. I have the same confusion.
Thank you sir
You're welcome
Sir Exact Topoisomerase ka function kya h plz in simple language and also tell me about DNA gyrase
Which enzyme removes the supercoiling in eukaryotics?
Topics type 1 and 2
Thanku.....Suman Sir........💓💓💓
very nice thank you sir
Does topoisomerase come before or after helicase ?
After
May God bless u....
Thank you
Thnku so much
You're welcome
sir wht iz the reason behind...Passing one strand throug the double nick....?
It's to resolve the supervoiled state and relax the DS DNA
What is the difference between DNA gyrase and topoisomerase IV? In bacteria
DNA gyrase is Topoisomerase II acting as a swivel to induce negative supercoiling from positive. And topoisomerase IV is responsible for termination of DNA replication
Nice language easy to understand
Sir why topoisomerase induces negative coiling
To reduce tension and structural stress in the DNA
Helpful
Good morning sir I am ur old student when I met u in Bangalore there was only 4 students 3girls and a boy(me). I m missing u sir.
I have a doubt that how dna polymerase distinguishes between dntps and ntps pls tell me sir
I remember. How are you now?
there are some aminoacids in the nucleotide binding pocket of dna pol(in the palm region of dna pol)called discriminator amino acids which helps to distinguish between dntp and ntps
Thank you
Thank u so so so so so much!!
sir plz plz plz make a video on sedimentation of pulse label n pulse chase. I'm very confused with this topic :((
+bosons botany sure. I will try to make a video on that topic
thanks sir
You are amazing congratulation!!! Really!! I finally understand how they works GOD thanks you MR! you save me!!
I don't think that is correct... in the second part of the video the primer in the loop…when you imagine you straighten the loop out... than the primers in both chains will be in the same direction….or…leading strand is 5‘ (on the left) - 3´(on the right) so lagging strand is 3‘ (on the left) than on the end of the loop it should be 5‘ ....but primer on it starts also with 5‘…Still thanks for your videos, your teaching helps me a lot!
Please use 3 dimension and explain it sir
Watching this video Just for tomorrow Exam
sir pls explain topology..
ur smart love ur videos:)
Thaanks
good stuff\
memem
great,,
I get it after all
❤❤❤❤❤❤❤❤❤❤
Thank you
Most welcome sir..
Sir plz go deep in topic
👍👍👍👍
You're welcome
In Hindi plz
Will come later
I love you Indian 😍
Thank you
Kuch koni smj aaya
Leave it
Hindi me
you better speak hindi.. making easier for both
I am not a native Hindi speaker
Insufficient knowledge.
Lake of knowledge
plz exam in hindi also
i have a question. does topoisomerase work only on circular dna or it can work also on linear one? please reply
Both