jCyte Developing Cell-based RP Treatment at Ophthalmology Innovation Summit @ AAO
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- เผยแพร่เมื่อ 17 ก.ย. 2024
- This company has developed a cell-based therapy (jCell) to preserve and restore vision in people with retinitis pigmentosa (RP), although the therapy is potentially applicable to other blinding diseases, as the treatment is nonsurgical and minimally invasive. jCyte is fully funded through its Phase IIb trial through the California Initiative in Regenerative Medicine (CIRN), and the company’s platform was granted breakthrough designation in 2017. Results from a Phase I/IIa trial (n=28) found jCell to be safe and well tolerated; the Phase IIb trial started during Q3 2017 and is actively enrolling. jCell has “extreme efficacy” in RP, said David Boyer, MD, one of the company’s investigators. jCell is human retinal progenitor cells that are not pluripotent; the mechanism of action is neurotrophic (not regenerative or reparative). “jCyte is the only cell therapy program using intravitreal injection of an ocular cell type versus subretinal,” Dr. Boyer said.
Waterfall plots showed at six months the majority of patients improved with treatment, and efficacy was between 5 and 10 letters in the 1 million and 2 million cell arms; it trended slightly higher to 10-15 letters in the 3 million cell arm, a trend that continued into 12 months.
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This is fantastic news! I've been following this specific trial for years.
Hi...Can you please update us on the work in progress?
Glad to hear this news kindly tell me when the treatment will be available to the patients
When is the medicine available for patient
It's in phase 3 now and will take 3'4 years to approve by FDA after that we are able to go for it. Hope I don't lose my eyesight till then. Pray for me
@@crazykatedits How do you know ... It won't take 3-4 years
@@umutsaryldz6825according to my knowledge, I think it takes at least a year to take notes of how patients are feeling after treatment and is there any side effects of the treatment or not. And I think clinical trials take at least 1'2 years and Jcyte is now going in phase three and then FDA approval so may be 2'3 years 😅 and there are also other ongoing clinical trials for the same but I'm following Jcyte cell therapy you can check this website www.jcyte.com
@@crazykatedits thanks I'm going to ask something, will the 3 phases take more than 1 year?
and when did phase 3 start ?
Some segments in the video are stamped not adjacent to each other
Now I have some hope .... Thank u
Hello when can I expect the medicine for general public can you tell me some date of
May be in 2024 or 2025
Can this for glaucoma patient
I been going to doctor hos visually impairment for my son since he was born they he is 29 years old he can't see nothing in the right eye little vision in the left please let me know if you could bring his vision back please 🙏 and God bless you thank you God bless you 🙏
I was diagnosed 3 years ago with RP and cataract. I had surgery to get rid of the cataract and my sight improve a little bit but I still can't see well. At night too little light and during the day too much light that is dificult to see. How can I contact you? Do you still have on going studies? Thank you.
EL OAXACALIFORNIO PROGRESISTA SARCASTICO I’m not answering on behalf of jcyte but i can answer this question..phase 2b is under trial and ongoing and is supposed to end this year.. you can go their website..jycte.com and you can volunteer for upcoming clinical trials. Hope this helps!
I have retinitis pigmentosa and was diagnosed with it at age 16 in 22 now now .. where do I go about the trial ??
🙏🙏Now complete treatment is available for all kinds of RP patience
🙏🙏
Phanindra Kopparthi Your PK world please give more information were it is available
Phanindra Kopparthi Your PK world ,yes sir please let we know ,where this treatment is available.
8 month age baby rop stage 5 any hope for this?
hi there, how can i avail this..but the problem is insufficient money to avail this treatment theres any way..im begging your help sir and maam..i need to work to support my family but i have this kind of disease..im from the philippines ..im willing to sacrifice my self to take over this kind of disease..thank you
please let me know how to avail this i have 3 children with rp
Fahey Manor
Necesito traducción al castellano
hindi.rp retinaitasis pigmentosa pathalogy sucesesfully hindi jankare treatment india m.p.
राजेश जी क्या आप अपना नंबर देंगे आपसे बात करनी है प्लीज
Pls give ur contact no.