I think all cancers have biomarkers, however, all biomarkers have not been discovered for all cancers along with treatments corresponding to these biomarkers. Cancer is such a weird disease to treat and cure. Not only because it involves a corrupted offshoot of ourselves, eukaryotic organisms, but also because every case is different. Some cancers are slow growing, some are aggressive and then some start off slow or aggressive and then become wildly aggressive after treatments. Chemotherapy, while life extending, is carcinogenic itself. Treatments can be prescribed based on the results of biomarker testing or some standard practice but I often wonder if there are secondary mutations that occur during treatment which cause the cancer to become even more aggressive and/or stop responding to current treatments. Cancer cells seem to have a 2-3 fold increase in their ability to “adapt” to the treatments which decreases patient survival rates. Again I say, Barrett’s esophagus is an interesting case of a tissue and its cells “adapting” to environmental stimuli. It raises the question about whether some “mutations” and ultimately cancer arise as a function of normal cells trying to adapt to persistent, harmful stimuli such as the Western diet and environmental poisons. I also wonder if stem cell therapy will become more common place. I just wonder what percentage of all Stage 1-2 cancers also involve cancer hiding in the stem cells. I just find it weird how some Stage 1-2 patients go NED and then 6 months later they present with Stage 4 metastatic disease. We are far from truly understanding this disease. If you get cancer, especially if it’s rare or aggressive, MD Anderson, Cleveland Clinic or a well known cancer hospital is your best bet for treatment and long term survival in my opinion. God Bless those with this horrific disease.
My husband has squamous cell carcinoma, he has no biomarkers ☹️ he is currently receiving carboplatin and pactiaxil, also 30 treatments of radiotherapy, after that he will receive nivoumeb apparently that is all that is available for him ☹️
A really well executed and interesting interview, the Doctors passion for her work is so evident. Thank you
Do a second part- talk more about the onc-genes and advancements in the medicines for each. You can start with ROS1.Thanks.
Thank you 🙏
I would be interested (if there is a part 2) on treatment for BRAF V600E mutation.
I think all cancers have biomarkers, however, all biomarkers have not been discovered for all cancers along with treatments corresponding to these biomarkers. Cancer is such a weird disease to treat and cure. Not only because it involves a corrupted offshoot of ourselves, eukaryotic organisms, but also because every case is different. Some cancers are slow growing, some are aggressive and then some start off slow or aggressive and then become wildly aggressive after treatments. Chemotherapy, while life extending, is carcinogenic itself. Treatments can be prescribed based on the results of biomarker testing or some standard practice but I often wonder if there are secondary mutations that occur during treatment which cause the cancer to become even more aggressive and/or stop responding to current treatments. Cancer cells seem to have a 2-3 fold increase in their ability to “adapt” to the treatments which decreases patient survival rates. Again I say, Barrett’s esophagus is an interesting case of a tissue and its cells “adapting” to environmental stimuli. It raises the question about whether some “mutations” and ultimately cancer arise as a function of normal cells trying to adapt to persistent, harmful stimuli such as the Western diet and environmental poisons. I also wonder if stem cell therapy will become more common place. I just wonder what percentage of all Stage 1-2 cancers also involve cancer hiding in the stem cells. I just find it weird how some Stage 1-2 patients go NED and then 6 months later they present with Stage 4 metastatic disease. We are far from truly understanding this disease. If you get cancer, especially if it’s rare or aggressive, MD Anderson, Cleveland Clinic or a well known cancer hospital is your best bet for treatment and long term survival in my opinion. God Bless those with this horrific disease.
What about information on EGFR germline mutation for non smoker NSC lung cancers, thanks!:)
My husband has squamous cell carcinoma, he has no biomarkers ☹️ he is currently receiving carboplatin and pactiaxil, also 30 treatments of radiotherapy, after that he will receive nivoumeb apparently that is all that is available for him ☹️
@jenniferderry4755 So very sorry for your husband!! I will pray for both of you to Our Lord and Savior Jesus Christ ❤❤
What kind of testing was done? Liquid or straight from the tumor ?
Please research Rick Simpson oil and believe it. I promise, if you keep an open mind, you have a very good chance to get your life back.