Just took my step 1 a week before this video was up. still happy this video exists. this topic is a pain, and now finally there's something that I can recommend for colleagues taking step 1.
For all you can add a note, the Leptomeningeal Angioma in Sturge weber is usually ON SAME SIDE of the Port-wine stain. Thin of it: like if half of the face has port wine stain, this port wine stain will continue posteriorly to the same side ONTO the Leptomeninges Capillaries(inside the brain).
Dirty you did it again. you shone a cool clear light on this eemingly confusing topic. Your caring heart comes through as we watch your teaching videos. Thank you so much for being there for us who are struggling to get through USMLE!
I am just learning for my German final medical exam and I am deeply impressed of your video! I really do thank you, I did not find any source which explains that quite difficult topic as understandable as you!
This is the best medical resource/content on youtube or any other platform so far. Thank you so much Dirty Medicine you have saved my ass from being toast in an exam countless times...I wish you well and hope you keep putting out such amazing content.🤘🏻✌🏻
For NF1, I just remember the phrase, "Bumpy brown kid." This describes the neurofibromas, the pigmentation of the skin and the eyes, and the fact that the onset is at childhood.
I have this disorder NF1, I had tumours in my small intestine, I had the biggest tumour in 2018 in North America, i had 7 tumours, lost about 50% of my small intestine. Tumours in my eyes and the Octave Nerve, Ringing Ears.
The pathophysiology of SWS is wrongly said. Here the GNAQ gene mutation leads to activation of the gene and its function, as in normal embryo, GNAQ gets inactivated at 9 weeks of gestation, but remains active in mutated cells in SWS
For VHL disease , you say the gene makes ubq 1a qhich shuts the complex that degrades proteins, then wouldn’t this gene cause less protein degradation?
Dirty please let me add sth for this great mnemonic … Tuberous Sclerosis … pronounce it: Tuberous Skinerosis.. for skin sx: Ash-leaf spots, shagreen, adenoma sebaceum, ungual fibroma on the skin of your finger. Taking my exam in few weeks, prayers 🙏🏼
Are the tram track calcifications in sturge weber due to leptomeningeal angiomas? If so are they on the same side or opposite side? First Aid says it's on the 'opposing gyri'
Great stuff as always! Big fan. I was wondering if it is important for the viewers to pay attention that in the HARP mnemonic it's hemangioblastoma and angioma- not vice versa (same shit for me but what if it is important) Thanks, Dirty, you are the best 👌
This is the highest quality content I've seen amongst all the resources, including the paid ones. Thank you!
Just took my step 1 a week before this video was up. still happy this video exists. this topic is a pain, and now finally there's something that I can recommend for colleagues taking step 1.
did you have any questions on these on step 1?
Remember the TUBArosclerosis genes/chromosome with this numerical mneumonic:
TSC1: (8+1) = c9
TSC2: (8*2)= c16
Love you, man! Stay dirty.
For all you can add a note, the Leptomeningeal Angioma in Sturge weber is usually ON SAME SIDE of the Port-wine stain.
Thin of it: like if half of the face has port wine stain, this port wine stain will continue posteriorly to the same side ONTO the Leptomeninges Capillaries(inside the brain).
Neuro-Cutaneous
-->
Leptomeningeal Angioma (Neuro) + Port-Wine Stain (Cutaneous)
Dirty you did it again. you shone a cool clear light on this eemingly confusing topic. Your caring heart comes through as we watch your teaching videos. Thank you so much for being there for us who are struggling to get through USMLE!
An add-on mnemonic for NF1: "I'll have a number 1, please. It's CUTE(-aneous neurofibroma) and de-LISCH-ous!"
Just wonderful addons bro😮❤
genius!!!!
CICLOPS
Cafe au lait spots
Intellectual disability
Cutaneous neurofibromas
Lisch modules
Optic gliomas
Pheochromocytomas
Seizures
Your channel is gold for USMLE. Thank you soo much for putting this up for free.
Your channel is the best for USMLE prep. Thankyou May God bless u always. Your mission to provide free education makes me teary eyes lots of prayers ❤
Thank you for keeping your resources free and helping to eliminate educational disparities, your channel is Amazing
Tuberous Sclerosis/TSC=> TS = tumor suppressor
In case for some reason knowing that it's a tumor suppressor in particular helps out.
I am just learning for my German final medical exam and I am deeply impressed of your video! I really do thank you, I did not find any source which explains that quite difficult topic as understandable as you!
Can’t thank this channel enough. Beyond grateful and obliged
Thanks!
best channel for mbbs students
No other teacher/resource could ever match up to you 🙏🙌
This is the best medical resource/content on youtube or any other platform so far. Thank you so much Dirty Medicine you have saved my ass from being toast in an exam countless times...I wish you well and hope you keep putting out such amazing content.🤘🏻✌🏻
For Sturge-WEBer syndrome I think Whites of eyes Epidermis Brain thanks so much dirty you're the GOAT!
For tuber sclerosis
Tubers are raised mass like potato
So potato in kidney, heart, nails, skin.
For NF1, I just remember the phrase, "Bumpy brown kid."
This describes the neurofibromas, the pigmentation of the skin and the eyes, and the fact that the onset is at childhood.
I have this disorder NF1, I had tumours in my small intestine, I had the biggest tumour in 2018 in North America, i had 7 tumours, lost about 50% of my small intestine. Tumours in my eyes and the Octave Nerve, Ringing Ears.
How are you doing now?
God help you get red if them😢
By far the best video I seen describing these difficult concepts
This content was amazing .... Dirty medicine never disappoints .... Amazing explanation
Saw this bs on my step 2 prep drove me nuts but this video is great.
You're a blessing for med students 🤩🤩
The pathophysiology of SWS is wrongly said. Here the GNAQ gene mutation leads to activation of the gene and its function, as in normal embryo, GNAQ gets inactivated at 9 weeks of gestation, but remains active in mutated cells in SWS
One day all I want is to finally understand the difference between angiomas, hemangiomas, and hemangioblastomas...
hahaha "That can quickliy spiral out of control if you dont know what you are doing" I LOVE IT... IDK why that made me laugh so hard! lol 😂
This is an outstanding presentation
For VHL disease , you say the gene makes ubq 1a qhich shuts the complex that degrades proteins, then wouldn’t this gene cause less protein degradation?
I'm so so so glad for this video!
best content ever! I cannot thank you enough!
Dirty please let me add sth for this great mnemonic …
Tuberous Sclerosis … pronounce it:
Tuberous Skinerosis.. for skin sx: Ash-leaf spots, shagreen, adenoma sebaceum, ungual fibroma on the skin of your finger.
Taking my exam in few weeks, prayers 🙏🏼
Excellent summary multiple thanks
Bet vedio keep it up❤
Such a wonderful and useful video!
I don't usually comment on videos but this is amazing!
I was he'll afraid of this topic always but then you came in my life
good one.
for sturge-WEBer , you can put a cartoon photo for spider man (with his WEB mask covering his head , face , eyes 🕸🕷😉)
Maxim Al Ali can you add more of mnemonics in the comment pls.... this stg web thing is so much easy for me now after this video
Your videos are amazing Sir. Just want to add a minor comment - TSC stands for Tuberous Sclerosis Complex I encountered at few places.
This is an amazing vedio⚡️⚡️
Thank you so much for this video!!!
Amazing..Thanks..Good Bless
Keep shining dear! You helped me a lot! Thank you so much
absolutely amazing.
Back here for STEP 2; thank you for helping me kill STEP 1 last year! You're a saint to us med students
Dirty your videos are the best. Thank u
Perfect as usual
Thank you sooooooo much, you’re a gem 💎 !
Thank you man! This is gold!
Thank you!!!💞💞💞
THANKS A BUNCH 💟💫
Thank you for this amazing video!!!
Are the tram track calcifications in sturge weber due to leptomeningeal angiomas?
If so are they on the same side or opposite side?
First Aid says it's on the 'opposing gyri'
same side
thank you!
Awesome video , thanks Dr 👍
Thank you.. I will study this
thank you
Your videos are really valuable👍keep going.
Love you. Thank youuuuu
Thanks for your kind help😁
Amazing explanation!
Mnemonic for NF type I and Café-au-lait spots:
If you drink too much coffee (Café-au-lait spots), you are gonna go number one (a slang for pee).
Amazing lecture!! Thank you!
thank you!!!
My comp is in a week brah! Thanks!
Is GNAQ mutation gain-of-function instead of knock-out/loss of function? It's activating mutation. Thank you
Great stuff as always! Big fan. I was wondering if it is important for the viewers to pay attention that in the HARP mnemonic it's hemangioblastoma and angioma- not vice versa (same shit for me but what if it is important) Thanks, Dirty, you are the best 👌
Thankyou so much ! I’m glad i found this👍🏻
Best❤
Thanks, I will add: Sturge starts with letter S= Sporadic. 😁
ive also seen seizures in a kid with tuberous sclerosis as a big sign for it!
Incredible
Hey!!!
Please make a video on dementia.. it’s getting very confusing
This is helpful! Thank you
Legend 🎉
Thanks
Awesome
❤
👍👍
great stuff man
great.. thaaaanks
Thank youuuuuu!
Counting down 👀
This is dirty indeed, but what a great job. Thank you.
Thanks a lot .This is like literally a life saver 😁❤️
🙏🏻🙏🏻🙏🏻
👏👏
I got picture of adenoma sebaceum on step 1 and asked for what other findings will be seen. I was like thank you dirty 🥺
I love you bro
2 ❤
dirtyusmle was a way better channel name, rolled of the tongue so well
I love u
I've forgotten to watch p*** after I found you.
❤
Thanks!