Love when I come across new quality home chemistry channels… maybe someday I’ll apply what my subconscious has absorbed. Seriously these skills could be as useful as foraging skills in a weird future
@@ShamefulAvocado Why isn't it wise? Ethylene glycol dimethyl ether is my favorite poison! Some people like ethanol, but Ethylene glycol dimethyl ether is my poison of choice.
Yes, and I called him a traitor and a coward for that. I'm glad, that you think like me. What I told him, in P.M. was "Man, do something in that great laboratory, built from the support of the community, do not be coward! Stop playing childish games!
@@petkotzvetkov6528 Yeah as much as i love the man the "fruit from random object" serie is getting pretty boring. I loved the aereogel synthesis video as he used supercritical CO2, something you can do only with the budget he has. Would love more complex projects from him, he even has a H-NMR!
Well, i can see chemiolis Is a real chemist and nile red is just an amateur. You can't just ask for nile to be at chemiolis level. Anyway let's give some credit to nile for great videos he has even he isn't a high level chemist, just a curious fella i think.
what i always do for bigger synthethis of ether is just place a small reflux condensor on top and hook it up to a PID loop to drop back everything until the vapor coming out of the top of the condensor is 36-40°C
Thank you! I saw at least one video (either from "nile red", or "chemplayer" or "dougs lab"), where the synthesis of diethyl ether took place in the presence of sand (in the 3-necked flask). I can't remember right now, what the purpose of the sand was, but maybe it is useful to improve your yield of the final product. But the starting materials are quite cheap, so don't mind too much.
To increase the efficiency of the reaction, it is necessary to shift the equilibrium, and this can be done by removing water, and for this you need to put a glass trap with the ability to drain the desired layer. When you use a dephlegmator - you don't need to wet it, just blow it with air from the outside - put a fan.
a taller column would also help if you happened to have one. the 2-4 ft columns are often wildly unnecessary for a lot of distillation/extraction, but certain fractions it is vital.
Maybe another explanation for the low yield, at 4:12 you leave ~200 ml and come back to a lot less the next morning, probably some ether evaporated overnight.
The column doesn't work in this synthesis. The point of heating to 140°C is that you distill off both water and ether. If the water remains, the reaction stops. In the industrial production the distillate is distilled again in spite of side products. Ethanol returns, and the crude ether is directed to next purification steps.
So just use any acid that has a conjugate base that is non-nucleophilic, right? So HCl here would not be a good choice, but maybe nitric acid could work?
React with lower temperatures first, then gently distill it. Ethyl sulfate will come over at a higher temperature as seen here, generally it will be EtHSO4 rather than the full ester. Adding a bit of anhydrous ethanol and magnesium sulfate will convert it to ether.
Remember viewers, the more useful a video is, the more likely it is to disappear. Take notes, because one day soon even the tamest of syntheses will vanish in a puff of blue smoke.
Is this the same stuff as brake fluid? Serious question though someone please help, i was doing a brake bleed on my car and was storing all the old fluid mixed with new dot 4 fluid in a bucked to catch it all and i spilled it on the concrete and grass (about 700ml) and now theres a big stain of the stuff and has contaminated a big area. I just want to know how long will the smell, stain and chemical will last and should i be worried? Everywhere i look it says that it's extremely toxic and is an environmental pollutant, does it linger forever or does is slowly degrade and become less toxic? What happens to it and what should i expect? I've already tried cleaning it and getting rid of the dirt but it still stinks very bad
Why has nobody mentioned that it’s far easier and cheaper to obtain this compound from common automotive starting fluid? Just distill out the lubricating oil.
I think you lost some when it sat overnight with the watch glass on top of the beaker, but maybe the calcium chloride had something to do with the volume change too idk.
Distilling ethers... bold! ;) Okay-ish in this case when the ether was freshly made. But generally questionable. It is one if the reasons for the myth chemistry were constantly exploding. Well... they do, if you distill old ethers. ;)
can dilute sulfuric be used instead of concentrated? let's say 70% sulfuric as far as I understand, the important step is the reaction temperature which should not exceed 140°C, wich is the boiling point of 60% sulfuric acid, so 70% should be fine, right?
It's called 'drysyn' and they are not really old as far as i know, they are a good replacement for oil baths and heating mantles. It's basically a heating plate to round bottom flask adapter. Good temperature control, no shorting when leaking liquid, not dirty and low temperature capped like oil baths.
I had a thermometer in the flask and it never went over 145 C so i don't think ethene formation was too significant. The vigreux was just too hot and ethanol came over before it reacted.
I'm interested to see if your diethyl ether will support a Grignard reaction. Diethyl ether can be hard to clean.up. If it doesn't work try distilling it over sodium. You might want to test it on a small scale first. Years ago diethyl ether was used for a general anesthetic. A person who had been put to sleep this way smelled of diethyl ether for days. In the days of my childhood there was an old wives tale circulated by doctors that ALL children had to have their tonsils removed and in 1973 I saw whole family of children taken into the local hospital and all their tonsils were removed in one day. I was receiving from a broken.ankle myself. Most insurance policies do not cover tonsil removal.
@@Chemiolis Another method is to make a small amount of methyl Grignard fresh and put that into your flask to kick things off. You will need a little methyl Iodide. Remember methyl iodide is a methylatiing agent and should be quite a biohazard.. Also remember that once the Grignard reaction gets going it's quite exothermic.
Love when I come across new quality home chemistry channels… maybe someday I’ll apply what my subconscious has absorbed. Seriously these skills could be as useful as foraging skills in a weird future
ON SPOT! Especially now with all the AIs pandora box opened. This will be a pretty useful skill. Just like foraging. :)
Nothing is more depraved than a man in the depths of an ether binge
i knew we would get into that rotten stuff pretty soon.
Your talking about Diethyl Ether? What about Ethylene glycol dimethyl ether. That shits on a whole another level.
@@Alex-ie5jl
that does not sound wise
@@ShamefulAvocado Why isn't it wise? Ethylene glycol dimethyl ether is my favorite poison! Some people like ethanol, but Ethylene glycol dimethyl ether is my poison of choice.
I'd like to sample some.@@Alex-ie5jl
This channel is much better than the Nile Red channel is. Especially these days. Keep up the great work!
Totally agree. I miss Doug’s Lab and Nurdrage. Nile Red just gave up when he realized he couldn’t monetize the interesting synthesis videos.
Yes, and I called him a traitor and a coward for that. I'm glad, that you think like me. What I told him, in P.M. was "Man, do something in that great laboratory, built from the support of the community, do not be coward! Stop playing childish games!
@@petkotzvetkov6528 Yeah as much as i love the man the "fruit from random object" serie is getting pretty boring. I loved the aereogel synthesis video as he used supercritical CO2, something you can do only with the budget he has. Would love more complex projects from him, he even has a H-NMR!
They are both equally good chemists, but they cannot synthesise what matters most… the love of a woman
Well, i can see chemiolis Is a real chemist and nile red is just an amateur. You can't just ask for nile to be at chemiolis level. Anyway let's give some credit to nile for great videos he has even he isn't a high level chemist, just a curious fella i think.
You're crazy man, you pump out geniunely high quality content so quickly. I'm excited to see where this youtube journey takes you.
honestly, a 45% yield for an ether synthesis is pretty good
O shit. New chemistry Channel. Nice production quality. Subscribed.
First. But seriously, this is a GREAT channel!
what i always do for bigger synthethis of ether is just place a small reflux condensor on top and hook it up to a PID loop to drop back everything until the vapor coming out of the top of the condensor is 36-40°C
Yeah, it's good to operate in total reflux initially
Deserves more views!
Thank you! I saw at least one video (either from "nile red", or "chemplayer" or "dougs lab"), where the synthesis of diethyl ether took place in the presence of sand (in the 3-necked flask).
I can't remember right now, what the purpose of the sand was, but maybe it is useful to improve your yield of the final product. But the starting materials are quite cheap, so don't mind too much.
To increase the efficiency of the reaction, it is necessary to shift the equilibrium, and this can be done by removing water, and for this you need to put a glass trap with the ability to drain the desired layer. When you use a dephlegmator - you don't need to wet it, just blow it with air from the outside - put a fan.
Excellent video my guy! please make more!
Hello, how do you remove the hydroquinone?
We studied to but KOH inside, and then remove it.
Does the hydroquinone not distribute the reaction?
If your reaction temperature was too high, most of the loss was probably in the dehydration of ethanol, making a bunch of ethylene gas.
Useful things to know if you don’t have an Ether Bunny to bring you presents of ether!
a taller column would also help if you happened to have one.
the 2-4 ft columns are often wildly unnecessary for a lot of distillation/extraction, but certain fractions it is vital.
How do u calculate the yield?
Maybe another explanation for the low yield, at 4:12 you leave ~200 ml and come back to a lot less the next morning, probably some ether evaporated overnight.
I’m pretty sure the reaction to form diethyl ether from ethanol is an equilibrium reaction, so a Dean Stark trap may be useful
yeah this why a dean stark or soxhelet are big +1s to have in your labware.
The column doesn't work in this synthesis. The point of heating to 140°C is that you distill off both water and ether. If the water remains, the reaction stops. In the industrial production the distillate is distilled again in spite of side products. Ethanol returns, and the crude ether is directed to next purification steps.
diethyl ether, my beloved
So just use any acid that has a conjugate base that is non-nucleophilic, right? So HCl here would not be a good choice, but maybe nitric acid could work?
I guess hcl won’t do. Sulphuric acid has another role here of shifting the equilibrium by absorbing the water. With hcl the yield would be very low.
Excellent. 👍
Nice. Always wanted to do diethylether by myself but didn't had a recipe
0:50 Looks like a NileRed video! But whithout forgetting an ingredient 😂
We made diethyl ether, but its smell is so strong that it hurts our noses. We are having a hard time even smelling it. Do you think we made a mistake?
Difficulties I have had in this reaction is the formation of both ethyl sulfate and acetaldehyde.
React with lower temperatures first, then gently distill it. Ethyl sulfate will come over at a higher temperature as seen here, generally it will be EtHSO4 rather than the full ester. Adding a bit of anhydrous ethanol and magnesium sulfate will convert it to ether.
Remember viewers, the more useful a video is, the more likely it is to disappear. Take notes, because one day soon even the tamest of syntheses will vanish in a puff of blue smoke.
Well, it’s only blue if you uhh… umm…
Is this the same stuff as brake fluid? Serious question though someone please help, i was doing a brake bleed on my car and was storing all the old fluid mixed with new dot 4 fluid in a bucked to catch it all and i spilled it on the concrete and grass (about 700ml) and now theres a big stain of the stuff and has contaminated a big area. I just want to know how long will the smell, stain and chemical will last and should i be worried? Everywhere i look it says that it's extremely toxic and is an environmental pollutant, does it linger forever or does is slowly degrade and become less toxic? What happens to it and what should i expect? I've already tried cleaning it and getting rid of the dirt but it still stinks very bad
Why has nobody mentioned that it’s far easier and cheaper to obtain this compound from common automotive starting fluid? Just distill out the lubricating oil.
I think you lost some when it sat overnight with the watch glass on top of the beaker, but maybe the calcium chloride had something to do with the volume change too idk.
Super! Thank you very much!
The original English name was "sweet oil of vitriol" which I think is so charming!
These videos are great👍, vaguely reminds me of nile red
Oh yeaa another good upload
Also please share the reference literature it will be highly appreciated
Distilling ethers... bold! ;)
Okay-ish in this case when the ether was freshly made. But generally questionable.
It is one if the reasons for the myth chemistry were constantly exploding. Well... they do, if you distill old ethers. ;)
Why do I feel like a chemist when I'm nerding out over making different metal alloys 🤷🤷. Other than my irrelevance, nice video as always!
can dilute sulfuric be used instead of concentrated? let's say 70% sulfuric
as far as I understand, the important step is the reaction temperature which should not exceed 140°C, wich is the boiling point of 60% sulfuric acid, so 70% should be fine, right?
I think it’s possible as long as the produced water doesn’t bring down the boiling point too much
Great high quality content! What was the inhibitor?
bruh how you only have 5k subs, this like 250k sub quality
i love making ether great fun
Hi, Why you cold reaction in start time?
It was most likely an exothermic reaction!
Can you please try to make dipropyl and dibutyl ether?
How old is that heating mantle?
It's called 'drysyn' and they are not really old as far as i know, they are a good replacement for oil baths and heating mantles. It's basically a heating plate to round bottom flask adapter. Good temperature control, no shorting when leaking liquid, not dirty and low temperature capped like oil baths.
@@Chemiolis its an basically a big chunk of Al right?
on my shopping list now
If you can flush the head space of your bottle with an inert gas you would extend the shelf life
Please make vedio on dimethyl ether
Why do ethers form peroxide?
photooxidation and or oxidation from ambient air/temp
en.wikipedia.org/wiki/Diethyl_ether_peroxide
When the temperature is way to high for this reaction, Ethene Gas (CH2=CH2) is formed, this could help to account for the small yield...
I had a thermometer in the flask and it never went over 145 C so i don't think ethene formation was too significant. The vigreux was just too hot and ethanol came over before it reacted.
What is the purity of diethyl ether?
I do this synthesis and purity is 50%
Reduce the amount of voltage to the pot. Too much energy going into mantle. You can maintain pot temp with lower voltage.
If the temp was too high will not there be some ethanol in it.... anyone ?
nice vid bro, what college did u graduate from?
Alternative title: making some kawaii chemical... that is until it finds an ignition source
The owls are not what they seem
Nice
big fan
Well at least u know why you had a small yield.
I'm interested to see if your diethyl ether will support a Grignard reaction. Diethyl ether can be hard to clean.up. If it doesn't work try distilling it over sodium. You might want to test it on a small scale first.
Years ago diethyl ether was used for a general anesthetic. A person who had been put to sleep this way smelled of diethyl ether for days.
In the days of my childhood there was an old wives tale circulated by doctors that ALL children had to have their tonsils removed and in 1973 I saw whole family of children taken into the local hospital and all their tonsils were removed in one day. I was receiving from a broken.ankle myself. Most insurance policies do not cover tonsil removal.
Yes i will do some tests first, also will dry the ether more. I have some commercial anhydrous diethyl ether to use if it doesn’t work out.
@@Chemiolis
Another method is to make a small amount of methyl Grignard fresh and put that into your flask to kick things off. You will need a little methyl Iodide. Remember methyl iodide is a methylatiing agent and should be quite a biohazard.. Also remember that once the Grignard reaction gets going it's quite exothermic.
*looks at the thumbnail*
Sir, that's a bird
Sick
Diethyl ether can get you high as hell, gotta be careful not to inhale it otherwise you WILL get high and knock you unconsious
Use it to get high
Aus Belgien und Nederland diethyl ether Sie könen kufen in alles apotek an. Mit zonder kontrol.
I wanna drink that
Can I just have some? I got some experiments I wanna do ;)
Batman chemical
Bump
Looks like a spider
I love you
Making meth thanks 😅