Bioreactor Scale-up and Optimization

Scaling-up and optimization of multiphase gas-liquid reactors (bioreactors and hydrogenation). Watch this webinar to learn about real industry application cases of CFD (Computational Fluid Dynamics) for accurate modeling of complex bio/chemical reactors. The rapid gas-liquid mass transfer coupled with mixing and gas sparger makes the application of these reactors very efficient. Optimized gas-liquid reactor results in time savings and increased profitability. However, design, scale-up, and optimization of these multiscale multiphase reactors are all still challenges in the industry.
This video is a re-recording of an online webinar by Siemens Simcenter on 22 September 2022 (webinars.sw.si...)
The experimental approach for scale-up and optimization of multiphase reactors is very expensive and time-consuming. The biological and chemical systems are complex, in addition to the complicated physical phenomena involved. Therefore, the interaction of bio/chemistry and scale-dependent phenomena (such as mixing) could strongly alter the process performance. In addition, the cost and resources associated with the scale-up limit the experimental optimization success. CFD simulations enable studying the interaction between the bio/chemical process and the scale-dependent mixing parameters and developing an optimized process in a rapid and efficient manner. The virtual case studies, scenarios, and multidimensional virtual DoE and optimization can be performed by CFD simulation in-silico for a wide range of parameters and goals.
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