Thank you Dr. Griggs..i was dx with Stage IIIa Lobular Cancer..the Grade was identified as 1-2..The cancer was found in 3 areas(5.5 cm, 3.0 cm, and 2.7 cm) of my breast(which is not uncommon, I guess for Lobular Cancer) .. what does having 2 different grades mean? Is it because of Lobular's structure is linear pattern tumor and not a a solid tumor?or is based on what foci they analyzed.? The pathology report summary did not describe each foci separately..probably it doesn't make any difference, but I just interested.. As i recall the Grade was not discussed with me..i remember the Oncologist indicated there was about a 73 % percentage chance of living 5 years..there were no clinical trials i could qualify for, i would need to have chemo, radiation, and ER inhibitors( which was the most important treatment of 3). I made it thru it all!! As i have shared with you before..it has been 14 yrs..still going strong!!!
Thank you for sharing your journey, and congratulations on reaching 14 years strong! Regarding your question, having two different grades in your lobular cancer can happen because the tumor might have different areas with varying levels of cell abnormality. Lobular carcinoma, with its linear growth pattern, can sometimes present differently in various foci, which might explain the differing grades. However, it’s usually based on what parts of the tumor were analyzed, and it might not significantly change the overall treatment approach. If you haven't watched our video on lobular carcinoma, we encourage you to watch it here! [th-cam.com/video/0IcNKZ7ccpw/w-d-xo.html]
Thank you for your kind words! While our videos provide general health information, we’re unable to offer direct consultations or specific advice. If you have a question, feel free to ask, and we’ll do our best to help!
Thank you so much for watching and for trusting us with your concerns. Unfortunately, we can't review test results directly. However, if you’re based in the U.S., your mother may benefit from a personalized Yerbba Report. This report provides tailored treatment options by cross-referencing her medical records, lab results, and specific tumor characteristics with the latest research and treatment guidelines. It also highlights the pros and cons of each treatment and is continuously updated with new medical information. You can learn more at Yerbba.com. Wishing your mom strength and clarity as she navigates her journey!
Mammograms and Pap smears are not considered detrimental. There are downsides to any screening test, such as over diagnosis of conditions that do not have clinical relevance, but early detection of cancers is so important.
There are a lot of options when endocrine therapy and CDK4/6 inhibitors no longer work. Fulvestrant, if not already given, may be effective as may tamoxifen. Depending on the other markers on the tumor, there are a host of other options.
Yes, it is possible to have a distant recurrence of breast cancer even with negative lymph nodes. Thirty percent of people with negative lymph nodes will develop distant recurrence., though it’s less common. Cancer cells can occasionally travel through the bloodstream, bypassing lymph nodes. Regular follow-up with your oncologist helps monitor for any potential recurrence.
Does DCIS comes back after Radiation? and if they do..(mines did. same breast and close to where it was radiated before ).what do you think is the next step someone can take?
DCIS can come back after the primary treatment. 50% of recurrences will be invasive, and 50% will be non-invasive. If someone had radiation therapy recently, a mastectomy is generally recommended because the skin cannot tolerate more radiation therapy. Make sure to subscribe to stay tuned for our upcoming video about DCIS, where we'll talk about this topic in more detail.
Dr Griggs is it possible to have a mucinous carcinoma and it also be Grade 2? Asking in terms that mucinous is considered to have a better prognosis. Would think it would be a Grade 1. Thanks.
Yes, it is possible to have a mucinous carcinoma that is Grade 2. The mucinous histology overrides the grade in terms of determining your prognosis, however. Thank you for watching.
Stage 0 refers to DCIS, which can indeed be classified as Grade 3, indicating a more "active" cell type despite being non-invasive. We have a video on DCIS that you might find helpful [th-cam.com/video/uc5eZArnv-Q/w-d-xo.html]. Also, we’re working on an updated version. Make sure to subscribe so you don’t miss it!
The '3+' may refer to the estrogen receptor score (high in your case) and is unlikely to refer to the grade. If you're based in the U.S., visit yerbba.com for personalized treatment options tailored to your unique tumor characteristics and overall health. Each Yerbba Report provides a comprehensive view of your diagnosis, ensuring that you're aware of all possible treatments, including those that may not have been mentioned by your doctor.
Thank you, Dr, Griggs, for your informative advice regarding staging and grading cancer status.
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Thank you for being part of our community!
Thank you Dr. Griggs..i was dx with Stage IIIa Lobular Cancer..the Grade was identified as 1-2..The cancer was found in 3 areas(5.5 cm, 3.0 cm, and 2.7 cm) of my breast(which is not uncommon, I guess for Lobular Cancer) .. what does having 2 different grades mean? Is it because of Lobular's structure is linear pattern tumor and not a a solid tumor?or is based on what foci they analyzed.? The pathology report summary did not describe each foci separately..probably it doesn't make any difference, but I just interested..
As i recall the Grade was not discussed with me..i remember the Oncologist indicated there was about a 73 % percentage chance of living 5 years..there were no clinical trials i could qualify for, i would need to have chemo, radiation, and ER inhibitors( which was the most important treatment of 3). I made it thru it all!! As i have shared with you before..it has been 14 yrs..still going strong!!!
❤
Thank you for sharing your journey, and congratulations on reaching 14 years strong! Regarding your question, having two different grades in your lobular cancer can happen because the tumor might have different areas with varying levels of cell abnormality. Lobular carcinoma, with its linear growth pattern, can sometimes present differently in various foci, which might explain the differing grades. However, it’s usually based on what parts of the tumor were analyzed, and it might not significantly change the overall treatment approach. If you haven't watched our video on lobular carcinoma, we encourage you to watch it here! [th-cam.com/video/0IcNKZ7ccpw/w-d-xo.html]
Thank so much Doctor.
Thank you for watching!
Thank you so much Doc!
Thank you for being part of our community!
Thank you Dr Griggs ❤❤
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We appreciate your support!
Thank you for your chanel. I am so happy when I listen to your videos.
I'm in South Africa. Would you offer me some advice ?
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Thank you for your kind words! While our videos provide general health information, we’re unable to offer direct consultations or specific advice. If you have a question, feel free to ask, and we’ll do our best to help!
Hello doc. Watched your video on TH-cam today, my mom was diagnosed of cancer. Please can I share the last test result she did recently with you?
Thank you so much for watching and for trusting us with your concerns. Unfortunately, we can't review test results directly. However, if you’re based in the U.S., your mother may benefit from a personalized Yerbba Report. This report provides tailored treatment options by cross-referencing her medical records, lab results, and specific tumor characteristics with the latest research and treatment guidelines. It also highlights the pros and cons of each treatment and is continuously updated with new medical information. You can learn more at Yerbba.com. Wishing your mom strength and clarity as she navigates her journey!
V Informative. Thanks
We're glad this video was helpful.
Hi Doctor, Could you please do a video on if a mammogram and pap test are detrimental as some people say?
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Mammograms and Pap smears are not considered detrimental. There are downsides to any screening test, such as over diagnosis of conditions that do not have clinical relevance, but early detection of cancers is so important.
Can you update more treatments on advanced breast cancer , esp when endocrine/CDKi therapy failed
There are a lot of options when endocrine therapy and CDK4/6 inhibitors no longer work. Fulvestrant, if not already given, may be effective as may tamoxifen. Depending on the other markers on the tumor, there are a host of other options.
Is it possible to have distant breast cancer occurrence with negative lymph nodes?
Yes, it is possible to have a distant recurrence of breast cancer even with negative lymph nodes. Thirty percent of people with negative lymph nodes will develop distant recurrence., though it’s less common. Cancer cells can occasionally travel through the bloodstream, bypassing lymph nodes. Regular follow-up with your oncologist helps monitor for any potential recurrence.
Does DCIS comes back after Radiation? and if they do..(mines did. same breast and close to where it was radiated before ).what do you think is the next step someone can take?
DCIS can come back after the primary treatment. 50% of recurrences will be invasive, and 50% will be non-invasive. If someone had radiation therapy recently, a mastectomy is generally recommended because the skin cannot tolerate more radiation therapy. Make sure to subscribe to stay tuned for our upcoming video about DCIS, where we'll talk about this topic in more detail.
Dr Griggs is it possible to have a mucinous carcinoma and it also be Grade 2? Asking in terms that mucinous is considered to have a better prognosis. Would think it would be a Grade 1. Thanks.
❤
Yes, it is possible to have a mucinous carcinoma that is Grade 2. The mucinous histology overrides the grade in terms of determining your prognosis, however. Thank you for watching.
@@yerbba Thanks so much! You help so many with your videos.
What about Stage 0? Is there such a classification? With Grade 3?
Stage 0 refers to DCIS, which can indeed be classified as Grade 3, indicating a more "active" cell type despite being non-invasive. We have a video on DCIS that you might find helpful [th-cam.com/video/uc5eZArnv-Q/w-d-xo.html]. Also, we’re working on an updated version. Make sure to subscribe so you don’t miss it!
My pathology report says :
ER+ 3+ 80%
Does any of those numbers specify the grade ?? Is the 3+ Is that the grade ??
The '3+' may refer to the estrogen receptor score (high in your case) and is unlikely to refer to the grade. If you're based in the U.S., visit yerbba.com for personalized treatment options tailored to your unique tumor characteristics and overall health. Each Yerbba Report provides a comprehensive view of your diagnosis, ensuring that you're aware of all possible treatments, including those that may not have been mentioned by your doctor.