Yeah, okay...So he can't say nuclei...but I can say nuclei, and not have the faintest clue about them. Sal can do chemistry. I can't. That's why I'm here.
Attack is a sufficient word. I remember my ochem teacher drilling to us the concept that SN2 is a backside attack in class and 4 or 5 immature students couldn't stop laughing. Still kinda funny, ha.
You're changing the world for the better. Free education, you deserve a Nobel Prize. Also, I really like how you personify the molecules. It really makes me feel like I have a personal bond to them. :)
I thank you, your vids made it possible for me to explain Sn2-reactions to a couple of teenage girls i've spent about a month trying to teach em about organic chemistry, i more or less rephrased it to a story about a guy and two girls (H and Br)
Thanks. And also inversion of the stereochemistry around the central atom for SN2 reactions. Happens in one step. Different from the SN1 reaction that happens via a carbocation intermediate. SN1 occurs in two steps while SN2 happens just in one.
really thanks this was awsome! This and your atoher videos explaine things better then my teacher does and i am so happy that i found yor videos its going to help me alot !
I watch all of your videos for Organic Chem at my university, and I can't help but be mildly distracted by the uncanny familiarity your voice portrays with Tyrion Lanister...#GOT
i did an sn reaction on a secondary halide iodoalkane and the rate was almost instant. we concluded this was an sn2 reaction with psuedo first order kinetics dependant on the concentration of the nucleophile. nice illustrations but it can be much more complex than it appears.
I'm not a fan of using double-headed curly arrows and saying that they show that a molecule gave an electron to another atom. Double-headed curly arrows, by convention, show movement of a pair of electrons. For example, we are moving a lone pair of electrons into a bond between two atoms. The explanation used in this video will make it very confusing for when radical mechanisms are considered, where a single-headed arrow is used to show movement of one electron.
Thank you for the video. The structure drawn towards the end of the video is actually the transition state, not the intermediate. Transition states and intermediates are not the same. An intermediate would be for example the carbocation in an alkene addition rxn. They're much more energetically stable than transition states
I loved it! just saying, but i also say things like "loudness" "rapidity" etc etc. i butcher english just cuz the language makes no sense anyway. i don't see why we shouldn't just play with it.
the tertiary carbocation is most stable but it would sterically hinder sn reactions so sn2 reaction only applies to primary or secondary carbons. they are slower on primary carbons.
@s05bf1c5 yea.I think that the oxygen giving up an electron is because H20 water already has a complete octet, since it's full and if it gains another electron it will violate the octet rule.I'm not sure. Secondly,Br is more electronegative so it's already giving C a partial +,since BR is a good leaving group,Br leaves.Then OH- attacks the C that has a partial +. OH- is the Nucleophile, it likes nucleousses that have positive charges. Since it's a Sn2 reaction,everything happens in one shot :)
I think its because the oxygen still has a partial negative charge that attracts the partial positive charge of the hydrogen on the other H-O-H. H and O have different electron affinities which explains the polarity of water. I hope I made sense lol.
In Bromomethane Bromine and Carbon are more electronegative than Hydrogen , the electrodensity is pushed to Bromine, why doesn't the Oxygen attack one Hydrogen atom in Bromomethane. Wouldn't the Hydrogens be more partially positive charged than Carbon, aka be more electrophilic?
can anybody link me to a video where he shows protection group chemistry using grignard reagents? i have good enough notes but id love to see how mr. khan teaches it
Actually both are used and both are okay. However I prefer nuclei as well. You don't get to use that type of plural too often, might as well use it when you can get away with it :)
I don't think so. OH is added here. When you add OH, you don't add it by itself. You have to buy it as NaOH, for example. On paper sometimes you don't see it when it's not necessary.
Why doesn't the bromine attract the electron first and become an Sn1 reaction? I mean i know how to differentiate between Sn2 and Sn1 but why is reaction the way it is?
I don't understand. At 2:20, why would oxygen give an electron to the hydrogen if he is more electronegative, he wants electrons, and then the oxygen gets a partial positive charge? I'm confused..
I would probably pass tomorrow's exam had I skipped this garbage prof I have who does not have his life in order, and should have spent that precious time taking notes here. Thanks!
Yeah, okay...So he can't say nuclei...but I can say nuclei, and not have the faintest clue about them. Sal can do chemistry. I can't. That's why I'm here.
alessandro felicetti ^^^^^real talk. Same here man
Give him a break on the nucleuseses. We're sciencers here, not languagers.
Scientists* linguists*
@@redmerdeboer1880 WOAH you must be fun at parties
@@redmerdeboer1880 lol
Khan Academy being lifesavers as usual.
Attack is a sufficient word. I remember my ochem teacher drilling to us the concept that SN2 is a backside attack in class and 4 or 5 immature students couldn't stop laughing. Still kinda funny, ha.
You're changing the world for the better. Free education, you deserve a Nobel Prize. Also, I really like how you personify the molecules. It really makes me feel like I have a personal bond to them. :)
nucleuses > nuclei
I thank you, your vids made it possible for me to explain Sn2-reactions to a couple of teenage girls i've spent about a month trying to teach em about organic chemistry, i more or less rephrased it to a story about a guy and two girls (H and Br)
Thanks. And also inversion of the stereochemistry around the central atom for SN2 reactions. Happens in one step. Different from the SN1 reaction that happens via a carbocation intermediate. SN1 occurs in two steps while SN2 happens just in one.
The confusion I had in class with SN2 is now clear by watching this video. Thank you.
seriously cant thank you enough for your chem vids. sooooo helpful id be failing ochem way worse then i am right now without these videos
When people ask me what university i graduated from ill just say ''KHAN ACADEMY''
Gosh how I'm so thankful to you! I've watched other vids for sn2 reaction but this video explains it best.
I appreciate your guys' vids. I like the enthusiasm you speak with.
> im not a greek scholar
doubt it
Wooow!!! I can't believe i was able to follow through 😱 Thank youu so much 👍👍👍
These are great! They really helped me before my ACS exam.
really thanks this was awsome! This and your atoher videos explaine things better then my teacher does and i am so happy that i found yor videos its going to help me alot !
You are really doing students a service!
I really appreciate your work, it's very helpful :)
I watch all of your videos for Organic Chem at my university, and I can't help but be mildly distracted by the uncanny familiarity your voice portrays with Tyrion Lanister...#GOT
nlindor87 who are you??
i did an sn reaction on a secondary halide iodoalkane and the rate was almost instant.
we concluded this was an sn2 reaction with psuedo first order kinetics dependant on the concentration of the nucleophile.
nice illustrations but it can be much more complex than it appears.
OMG thank u so much for this! I can finally understand it =D
this is so good. so useful for tmr's exam. thank you so much!
I'm not a fan of using double-headed curly arrows and saying that they show that a molecule gave an electron to another atom.
Double-headed curly arrows, by convention, show movement of a pair of electrons. For example, we are moving a lone pair of electrons into a bond between two atoms.
The explanation used in this video will make it very confusing for when radical mechanisms are considered, where a single-headed arrow is used to show movement of one electron.
Truly helpful and thank you.
Thank you for the video. The structure drawn towards the end of the video is actually the transition state, not the intermediate. Transition states and intermediates are not the same. An intermediate would be for example the carbocation in an alkene addition rxn. They're much more energetically stable than transition states
Nucleuses hurt me, just say nuclei.
it's an insult of chemistry
rohit choudhary So what good have u done to raise the standards of chemistry? better then sal khan?
Then you are a masochist, you don't have to watch this video...
I loved it! just saying, but i also say things like "loudness" "rapidity" etc etc. i butcher english just cuz the language makes no sense anyway. i don't see why we shouldn't just play with it.
Zombie Salad who cares. It’s not about remembering and pronouncing everything flawlessly, it’s about understanding
*His use of nucleus says nucleus is nucleuses if nucleus suits nucleus-nucleus stress synthesis, I guess.*
idk what I would do without you, khan academy
You are really doing a service for students!
holy shit the buildup to that NUCLEUSESES was so hype. I loved it. NOT even gonna timestamp it for anyone.
thanx man.yours a great help
think your Ochem videos will help me in cracking iit-jee
Chemistry isn't really my favourite subject at all... but I love organic chem....
finally knew understood what sn2 reaction is :D thanks
"Will attack the Carbon... Or, I shouldnt say attack that sounds very aggressive" Lol.
i'm spuddering here - not as hungry for it, doesn't grab me
why does the "whole" Bromide leaves when recieving the electron from the hydroxide?
You are wonderful! Thank you so much.
Nucleophilic substitution made even simpler ,explained from a layman's approach hence simpler.
#thumps up
Now, I'll never forget that nucleophile loves nucleuses! lol
the tertiary carbocation is most stable but it would sterically hinder sn reactions so sn2 reaction only applies to primary or secondary carbons.
they are slower on primary carbons.
@s05bf1c5
yea.I think that the oxygen giving up an electron is because H20 water already has a complete octet, since it's full and if it gains another electron it will violate the octet rule.I'm not sure.
Secondly,Br is more electronegative so it's already giving C a partial +,since BR is a good leaving group,Br leaves.Then OH- attacks the C that has a partial +. OH- is the Nucleophile, it likes nucleousses that have positive charges. Since it's a Sn2 reaction,everything happens in one shot :)
Without him I think many college classes would be failed
how do we identify a Sn1 from a Sn2 reaction?
I think its because the oxygen still has a partial negative charge that attracts the partial positive charge of the hydrogen on the other H-O-H. H and O have different electron affinities which explains the polarity of water. I hope I made sense lol.
Tell me why Im learning more from an 11 minute khan academy video from 11 years ago than my entire ochem lecture over SN2 reactions
In Bromomethane Bromine and Carbon are more electronegative than Hydrogen , the electrodensity is pushed to Bromine, why doesn't the Oxygen attack one Hydrogen atom in Bromomethane. Wouldn't the Hydrogens be more partially positive charged than Carbon, aka be more electrophilic?
so helpful! thankyou
its also totally easy to learn that way!
This guy is the s**t. Very helpful in conceptualizing Ochem and very useful for the MCAT. I wish I had this when I was in school.
Awesome.
Great! 😊
10 years later and you’re the reason I’m passing
You saved me, thanks
THANKS SO MUCH, BE BLESSED
Me in orgo class :(
Me watching your vids :)
Keep up the good work!
what would happen, if you had a primary or secondary carbon ?
Sn2 doesn't occur in tertiary carbons due to steric hindrance though, yeah?
can anybody link me to a video where he shows protection group chemistry using grignard reagents? i have good enough notes but id love to see how mr. khan teaches it
Keep up your amazing work
Thanks for your unconditional love and support 🌹🌹🙏🙏🙋🙏🙏🙏 where are you from please?
so the bromide just breaks out of the molecule
Thanks guys!!!
The famous backside attack.
our teacher called this the "back side attack". you said they have to "bump into each other the right way." lol,
very clear! thanks!
Hhahahaah, very true. He's actually in the middle.
the plural of nucleus is nuclei!
fucking liar
Actually both are used and both are okay. However I prefer nuclei as well. You don't get to use that type of plural too often, might as well use it when you can get away with it :)
this would be true if he were talking about free radicals; however, these reactions are understood to be involving both electrons.
amazing
love it.
ahh i see what you did there... 'personal "bond" ' :P
Thank you team Khan Academy
ok i´ll make it quick..I LOVE U SIR !
I don't think so. OH is added here. When you add OH, you don't add it by itself. You have to buy it as NaOH, for example. On paper sometimes you don't see it when it's not necessary.
love u sir...thank u...!!!
@imkaneforever "It really makes me feel like I have a personal bond to them" I see what you did there =P
Woah a 7 year old comment.
instead of H20 u may think of the reaction with OH- (even)
Why doesn't the bromine attract the electron first and become an Sn1 reaction? I mean i know how to differentiate between Sn2 and Sn1 but why is reaction the way it is?
MENTION IN ONE OF THE ABOVE COMMENTS IN REPLY SECTION ON TANISSTHAS 2ND COMMENT.. DO WATCH IT :)
thnk god i found dis,i just couldn't bear readin boring org chem books...
the positive ion to balance it is not drawn for simplicity
Does it bug anyone else that he called the Br(-) Bromine? I always thought it turned into a "Bromide Ion."
haha alright so hes kinda creeped out probably..kinda loving it..hahah
nice video... i understood evrything... superlykk
THANK YOU!!!
thank you sir !!!!!! :)
Thank you a lot
Seven, seven valence electrons, ah ha ha ha ha!
I don't understand. At 2:20, why would oxygen give an electron to the hydrogen if he is more electronegative, he wants electrons, and then the oxygen gets a partial positive charge? I'm confused..
Actually, no. Both forms of the plural are equally acceptable.
Great video as always.
In the SN2 reaction, it is improper to show single-electron species.
in my dialect it is nucleuses.
''I'm not a greek scholar''
I would probably pass tomorrow's exam had I skipped this garbage prof I have who does not have his life in order, and should have spent that precious time taking notes here. Thanks!
love you fam
Aye.
nucleuseses! yess
good
Khan academy to the rescue!!! Taadaaa...!!!!
The plural form for "nucleus" is "NUCLEI"