With two-colour detection system in SNP array (let's say Infinium HD), does it mean that if the target SNP has a G to C or an A to T change, then it will not be helpful because both alleles will give the same fluorescence? When designing a SNP array how do they get around it? Do they just avoid using these targets?
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With two-colour detection system in SNP array (let's say Infinium HD), does it mean that if the target SNP has a G to C or an A to T change, then it will not be helpful because both alleles will give the same fluorescence? When designing a SNP array how do they get around it? Do they just avoid using these targets?
Great explanation! Thank you so much
How is the dna labeled?