Treating Lymph Node Metastases

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  • เผยแพร่เมื่อ 4 พ.ย. 2024

ความคิดเห็น • 85

  • @trailrider9526
    @trailrider9526 ปีที่แล้ว +15

    I just cannot thank both of you so much for the excellent information. This information has been so helpful while navigating my advanced prostate cancer. Keep up the excellent work!!!

  • @kevinvitale8980
    @kevinvitale8980 ปีที่แล้ว +15

    Love these conversations/discussions by Alex and Dr. Scholz. Thank you so much for understandable language.

  • @colemant6845
    @colemant6845 ปีที่แล้ว +4

    Alex, Again... THE BEST Questions Asked and the Best Dr. answering them. Well Done. Thank You! You are helping millions of men.

  • @roboodonnell3224
    @roboodonnell3224 ปีที่แล้ว +9

    Thanks! You folks are very much appreciated!

  • @tnvol5331
    @tnvol5331 7 หลายเดือนก่อน +4

    What about a singular non enlarged lower abdominal lymph node metastasis?

  • @edmundpeshall511
    @edmundpeshall511 ปีที่แล้ว +2

    I happened upon this particular video dealing with lymph node involvement at precisely the right time. Thank you so very much for the education, the information, and the guidance.

  • @LarsSchaferVP
    @LarsSchaferVP 10 หลายเดือนก่อน +2

    This channel is gold. I just got result of PSMA Pet scan, (done with the advice from PCRI ;-)) and it said all is contained in the prostate exept one little lymph node right next to the prostate. With a PSA at 124 when I first got tested, I feared much worse. :-) But, here is a kicker (a topic that saw me thrown out of a prostate cancer support group on Facebook with 30K members :-( ) I have had 5 PSA tests. First in August was 124. Got on antibiotic because of prostatitis for a full month. PSA down to 97. Following month I did not much but research. No change to my life. PSA climbed to 120. Then I decided to see if I could do something about it myself. After a month PSA 93. And I just had the last PSA after another 1.5 month and my PSA is 78.71. I want this out, but I do not want to try other options first. So, what would be a smart thing to do? One single lymph node got cancer right next to the prostate, but my PSA is trending down without treatment. My Gleason score was 5+4 by the way, and only 3 cores taken. It was too painful. ;-)

    • @FightingProstateCancer
      @FightingProstateCancer 8 หลายเดือนก่อน +1

      PSA can fluctuate but 78 is way too high. You won't heal it all by yourself. You should do something with it before it gets worse.

    • @LarsSchaferVP
      @LarsSchaferVP 8 หลายเดือนก่อน

      I follow the PSA very closely, and I am prepared to accept that I might need both ADT and Radiation, but I am measuring my progress by the same means urologists do, so as long as I can keep it from going about the initial number, and as long as I think I got alternatives, then I will continue my efforts to bring this to an end on my own. Once on medication, I can no longer verify progress using PSA, and right now I am a healthy 54 year old, with ZERO sympthoms and issues, but the same second I take the jab, I am a sick man with compromised immunesystem. And this to do what I am doing now, without being compromised. @@FightingProstateCancer

    • @FightingProstateCancer
      @FightingProstateCancer 8 หลายเดือนก่อน

      PSA is only 1 of the markers. You are lucky that with your extremely high PSA the cancer is contained to prostate and to 1 lymph node. But it's already in the lymph node, so it's not that great. Gleason 5+4 is extremely aggressive as you can see - it means that the cells can live outside the prostate. You say that you have "only 3 cores taken", yet your lymph node is already hit.
      You are lucky that you had a PSMA PET Scan. This scan is quite new, expensive and even in developed world not so easily accessable.
      You are not healthy, you have cancer. You should hit it with intention to cure and continue with normal life.
      Don't you have a family, friends or someone who may be worried about you?
      You are not symptomatic - prostate cancer is symptomatic only in the last stage. Lucky for you, prostate cancer is one of the slowest cancers. Yet it slowly gets there.
      If you don't like the pain, then you should cure it now.
      Try the Staginq quiz on: pcri.org/staging-quiz
      And read The Prostate Cancer Staging Guide on: static1.squarespace.com/static/54c68ac6e4b06d2e36a4b8c9/t/5b27f0fc575d1f7e236b578f/1529344254467/The+Prostate+Cancer+Staging+Guide+web.pdf
      Or buy the book "The Key to Prostate Cancer" by Mark Scholz, MD from year 2018.
      The Prostate Cancer Staging Guide on the web is almost the same as the book "The Key to Prostate Cancer"
      I think you would fall into stage named "High-Azure".
      You're lucky that it was found.
      Hope that helps. @@LarsSchaferVP

    • @TERRY-cb2ku
      @TERRY-cb2ku 8 หลายเดือนก่อน

      @@LarsSchaferVP I wish you the best of luck, and I will pray for you.

  • @dwmcever
    @dwmcever ปีที่แล้ว +4

    Age 71. Prostrate Cancer Stage 4, Gleason 9; 2 Tumors, one in lymph node near Prostate and one in Prostrate per PET Scan. This video matches my Medical Team's opinion exactly. On 2 Hormone Pills and Radiation treatment. My goal right now is to get my PSA score down from 10 to something normal. Then we'll go from there. This is a great video for me. Thanks.

    • @koof1776
      @koof1776 ปีที่แล้ว

      Are you okay?

    • @jabster58
      @jabster58 5 หลายเดือนก่อน

      Like to know how its going..I have the same thing

    • @jabster58
      @jabster58 5 หลายเดือนก่อน

      Hello

    • @luishernandezdavila8231
      @luishernandezdavila8231 หลายเดือนก่อน

      how are you doing Im in the same boat!

  • @lsu205
    @lsu205 2 หลายเดือนก่อน +1

    as always great videos. Where does he get those ties???

  • @jazandriz
    @jazandriz หลายเดือนก่อน

    Thanks this video made me feel better.

  • @SharonSmith-ip2kr
    @SharonSmith-ip2kr 5 หลายเดือนก่อน +2

    Thank you. Alot questions answered. My husband has aggressive stage 4a prostrate cancer in the lymph nodes. His cancer is also in the whole prostrate. I'm worried. Surgery is not an option. He will be having hormone therapy and radiation. Sees cancer doctor on Tuesday. I pray this will take care of it. 😢🙏🙏

    • @christined2495
      @christined2495 4 หลายเดือนก่อน

      Sharon’s ithip2kr. How is your husband doing, my husband was just diagnosed with same exact diagnosis as yours, he received his first hormone shot last week

    • @cmrjc74
      @cmrjc74 2 หลายเดือนก่อน +2

      I’ve recently been diagnosed with pc Gleason 9 5+4 in all nodes with psa of 70. I’ve been on zytiga and orgovux for a month and a half and it’s dropped my psa to .26 I’ve done three radiotherapy out of 23 and then I will do brachy therapy my radiologist mentioned he’s going for a cure not out of the realm of possibilities he says… good luck

  • @cloudsculptor1
    @cloudsculptor1 ปีที่แล้ว +4

    Excellent info.
    What’s your take on the mitochondrial link to cells turning cancerous?

  • @robertmonroe3678
    @robertmonroe3678 ปีที่แล้ว +5

    Robotic Surgeons at UCLA are now using PSMA expression in real time to target and extract cancerous lymph nodes and to check in real-time that no cancer is left behind. “PSMA Radioguided Surgery”. Very clever.
    Once PSMA PET emerged (UCLA was a very early site) the challenge has been to harness some aspects of it to destroy the prostate cancer it is so good at locating. (lutetium-177 PSMA therapy is another effort in this direction).

    • @gerard2620
      @gerard2620 10 หลายเดือนก่อน +1

      I just watched the UCLA video on radio guided surgery. Looks promising, but not sure if it's been adopted anywhere else ? Also, the UCLA video I watched stated that the 'benefit remains unknown'.

    • @Goldiehaws
      @Goldiehaws 12 วันที่ผ่านมา

      ​@@gerard2620I believe.

  • @osaether
    @osaether 19 วันที่ผ่านมา

    Great video! One comment: I live in Norway/Europe and have aggressive prostate cancer but nobody told me what Gleason score I have.
    Suggestion: Explain this score or stop mentioning it.

    • @Goldiehaws
      @Goldiehaws 12 วันที่ผ่านมา

      The best Gleason score is 0.00 but 1+1 is well and good. Maybe a BPH. PSA of less than. 0.010 is also good. A prostate volume of 15 to 20 m.L. is also good.

  • @frankmoen4666
    @frankmoen4666 ปีที่แล้ว +2

    EXCELLENT many thanks Dr. Scholz and Alex

  • @stevemolyneux-e2k
    @stevemolyneux-e2k ปีที่แล้ว

    Fantastic, just diagnosed with lymph node metassis very helpful

  • @mikerose6835
    @mikerose6835 ปีที่แล้ว +1

    Thanks for an excellent discussion about lymph nodes.

  • @robbujold7711
    @robbujold7711 ปีที่แล้ว +3

    I’m struggling with the “one and done” approach vs trying to minimize radiation side effects. I have unfavorable intermediate and my radiation oncologist says my risk of lymph node involvement is somewhere between 10 and 15%. Says I could go either way when it comes to radiating the lymph nodes or not as part of my initial treatment.

  • @agastful
    @agastful ปีที่แล้ว +1

    Thank you ✌

    • @ThePCRI
      @ThePCRI  ปีที่แล้ว

      You're welcome 😊

  • @rockycotugno5655
    @rockycotugno5655 2 หลายเดือนก่อน

    ALex love your empathy. is there any way to contact the doc. I had 3+4 then they removed prostate Been on elligard, 11 yrs, Casodex and Nubeqa 4 years each PAS 11.7 Had PSMA showed some lymph growth. 3 months later regular Pet scan showed nothing. Latest Pet shows same lymphs enlarged again

  • @tommaloney8874
    @tommaloney8874 ปีที่แล้ว +1

    Dr Scholz,
    I have gained tremendous insight into prostate cancer by doing research wherever your videos have led me. Would you give hints as to where to go for support groups?
    I have failed all treatments including Pluvicto and docetaxel.
    Would you explain late stage prostate cancer?

    • @ThePCRI
      @ThePCRI  ปีที่แล้ว

      Hello Tom,
      Thank you for your kind words.
      One of our team members, John Shearron, is an advanced prostate cancer support group leader and would be a great resource: pcri.org/john-shearron | Please feel free to reach out to him via this link: pcri.org/helpline
      Here are some support groups and advocacy groups:
      ancan.org/prostate-cancer/
      www.cancerabcs.org/contact-us
      zerocancer.org/get-support/peer-support/find-a-support-group/

  • @barrie888
    @barrie888 ปีที่แล้ว

    i learn a lot as usual tks

  • @davegillteam
    @davegillteam ปีที่แล้ว +2

    I had psa of 1,300. Came down to .11 within 2 months. Does that mean, no more cancer or cancer stopped growing?
    I’m taking Lupron shot every 3 months, taking Xtandi 160 mg, biclutamide. I’m also getting shot of xtigo every month. However I fractured my knee. What caused it?

  • @mikelebo9140
    @mikelebo9140 ปีที่แล้ว +3

    Are there lymph nodes that are not treatable with radiation because of their location ?

  • @Sophomore451
    @Sophomore451 ปีที่แล้ว

    Thank you

  • @pattyg6803
    @pattyg6803 ปีที่แล้ว +1

    What if prostate cancer has spread beyond the pelvic lymph nodes? What if it has spread to lymph nodes near stomach region? What are the percentages of curing it then?

  • @DaveLeoni
    @DaveLeoni ปีที่แล้ว

    Can you get a PSA bump after SBRT to lymph nodes? Thank you

  • @rowdyson2654
    @rowdyson2654 ปีที่แล้ว

    My PSA was 7.7 Gleeson 6.. I underwent 5 SBRT sessions and 6 weeks after last session my PSA was 4.4 . 6 months later PSA has jumped back to 6.5. Is this just PSA bounce or something recurrent ? I have PSMA -PET scan scheduled in a 2 weeks

  • @annerodriguez4470
    @annerodriguez4470 5 หลายเดือนก่อน

    Thank you for this information I’m in the beginning stages of anal cancer and found out I have lymph nodes metastatic need more information just starting radiation will have biopsy

  • @gouridhatt
    @gouridhatt ปีที่แล้ว +2

    if psa is less than 0.04. is it useful to have PSMA scan or wait till PSA reaches 0.2 or more

    • @Mary-bx8gd
      @Mary-bx8gd ปีที่แล้ว

      Good question, I hope you get an answer, my husband is in the same situation.

    • @crankyneanderthal6784
      @crankyneanderthal6784 ปีที่แล้ว +4

      I am from Australia and I recently completed 25 sessions of targeted radiation on cancerous lymph nodes in my clavicle and abdomen/pelvic region. 6 weeks following radiation my PSA dropped to 0.03 ug/L (using Roche Cobas method) which my Radiologist (Prof Shankar) classed as undetectable. According to the Professor, if my PSA rises to 0.2 ug/L then a PSMA PET scan will only be 30% accurate whereas if the PSA rises to 0.5 Ug/l then the PSMA PET will be 50% accurate. Generally speaking, the higher the PSA level, the more likely a PSMA PET Scan can detect and identify recurrent prostate cancer. Whilst the PSMA PET is fantastic it has a limited resolution of 2-3 mm. Anything smaller, particularly microscopic cancer cells, will not be detected. That is why the PSA has to rise to a certain level before it "may" be visible on a PSMA PET scan. It will up to your oncologist to decide when best to carry out a PSMA PET scan.

    • @blackknight125
      @blackknight125 ปีที่แล้ว

      You should ask your doctor can I be watch in your case he may want to do the psma talk to him let them know what you want

    • @stevenpeterson659
      @stevenpeterson659 ปีที่แล้ว

      I know this because I am in the Mayo series. Mayo Clinic has a developing case series of PSA negative people with positive PSMA PET/CT. A similar case series is also being collected in Australia.

  • @stevemolyneux-e2k
    @stevemolyneux-e2k 4 หลายเดือนก่อน

    Psa went down to 1.7 after sabre treatment then to 1.5 but last test up to 1.6

  • @Rockinrn
    @Rockinrn ปีที่แล้ว +1

    Am having IMRT for local lymph node involvement. The only real side effect I’m having is diarrhea. Doctor suggested diet changes and Imodium.

    • @arminius61
      @arminius61 หลายเดือนก่อน

      @Rockinrn Take care with Imodium. Long term use results in serious changes to the bowel function. Good idea to discuss further.

    • @Rockinrn
      @Rockinrn หลายเดือนก่อน

      @@arminius61 I didn’t really take that much of it and I’m done now. No lasting side effects.

  • @trevorhoskins7643
    @trevorhoskins7643 ปีที่แล้ว

    After chemo and radiation my psa 0.010 for four years and five months.threeonths ago the testerone level eas 56 last week the number is 105.the psma pet is negative.what is the number for testosterone to be

  • @gvet47
    @gvet47 ปีที่แล้ว +11

    When they told me I had prostate cancer it had already spread to most of my lymth nodes. My PSA was 5000. They started hormon therapy and nobody told me how bad that can be. Sweats that last for hours or even all day. Wake at night with pillow and beding soaked from sweat. Hair soaked and running down my head and damaged hearing aides. he is totally wrong as hormon therapy has terrible side affects. Now I have had problems with passing out and falling.

    • @captainamericaamerica8090
      @captainamericaamerica8090 ปีที่แล้ว +1

      Medical doctors almost killed my gramps

    • @waynevarrelman9363
      @waynevarrelman9363 ปีที่แล้ว

      Try fasting with a keto diet my friend. By doing this it starves the cancer from glucose and glutamine, there energy source.The good cells live off the fatty ketones. They don't talk about this because it's not profitable! There are thousands of studies that are shown to be 85 to 90 % effective. Look into it GL

    • @gvet47
      @gvet47 ปีที่แล้ว +2

      My doctor never told me I would get enlarged breast and now on these video I hear that could have been prevented at the start. I cannot even get an appointment and just go to get treatment every three months. Only can speak to his nurse. Is that how everyone is treated. Binder in Albuquerque.

    • @guyonabike2415
      @guyonabike2415 ปีที่แล้ว +2

      Ask your doctor for meds to control the hot flushes. Mine weren’t as bad as yours but I got the meds anyway.

    • @gvet47
      @gvet47 ปีที่แล้ว

      ​@@guyonabike2415My doctor does very little communication with me. Like my cancer is so bad not worth dealing with me. At least my palliative nurse does more. Helps maintain pain meds as pain increases. Has tried multiple drugs to slow the terrible sweats.
      I have a bad heart and a pacemaker. I thought my heart doctor and oncologist would communicate more as one affects the other but nope.

  • @azhagudevi-hv7bp
    @azhagudevi-hv7bp 7 วันที่ผ่านมา

    Hello sir my brother faced lymph node cancer 😢

  • @jabster58
    @jabster58 5 หลายเดือนก่อน

    What about lymph node sugery removeable

  • @Mary-bx8gd
    @Mary-bx8gd ปีที่แล้ว

    If you’ve been through treatment such as chemo, and your PSA is undetectable at this point, is it useful to get a PSMA-PET? It’s been two years. Would you expect to see any new Mets? Please answer.

    • @blackknight125
      @blackknight125 ปีที่แล้ว +1

      I say only time will tell how it's going to go may God be with you I am in the same boat waiting to see what happens really sucks

    • @stevenpeterson659
      @stevenpeterson659 ปีที่แล้ว

      I know this because I am in the Mayo series. Mayo Clinic has a developing case series of PSA negative people with positive PSMA PET/CT. A similar case series is also being collected in Australia.

    • @Mary-bx8gd
      @Mary-bx8gd ปีที่แล้ว

      @@stevenpeterson659 I’m not sure what you mean, can you explain?

    • @stevenpeterson659
      @stevenpeterson659 ปีที่แล้ว +1

      @@Mary-bx8gd There are clearly a group of patients who predominantly have been diagnosed with high Gleason Scores who have been treated and now have PSA levels below the level of detection by the test. However, if you do a PSMA PET/CT you will find PSMA positive lesions that are recurrent or persistent foci of prostate cancer. Insurance has set a requirement of a PSA of 2 for a PSMA PET/CT, this requirement is probably not valid in all patients.

  • @georgezorn4914
    @georgezorn4914 ปีที่แล้ว

    Would Pet Scan give any more data?

    • @ThePCRI
      @ThePCRI  ปีที่แล้ว +1

      Hello,
      Our helpline may be able to give you more information about PSMA PET scans. You can find their contact information at pcri.org/helpline.

  • @lesleymorris
    @lesleymorris ปีที่แล้ว +1

    We have been told that because my husband had radiation therapy 17 years ago after having his prostrate out!!
    he can’t have it again to treat cancer now found in the prostrate bed they have said it might do damage to surrounding area

  • @buratching
    @buratching 11 หลายเดือนก่อน

    🥰

  • @georgemohr7532
    @georgemohr7532 ปีที่แล้ว

    I watch your videos which are helpful. That said, there is one aspect that is not clear to me. I was a Gleason score 9, had surgical removal of the prostate. Approx. one year after surgery PSA began to rise and then treated with ADT and radiation. PSMA pet scan was not yet available. Currently I am in remission based upon my PSA. From a statistical perspective, having been a Gleason score 9 am I at a greater risk of future disease recurrence?

    • @blackknight125
      @blackknight125 ปีที่แล้ว

      You know I would like to know that myself mines is a very aggressive type cancer 4+3 also 4+5
      I otp to have it removed it bout to be a year a month I know it kills me to have to go through life wondering if and when it's going to come back

    • @richelledejong4863
      @richelledejong4863 ปีที่แล้ว

      @@blackknight125 we’re you stage 4 Gleason 9 and went into recommission. My father is Gleason 9 stage 4 and was diagnosed in November. How long did it take for you to go into remission and how long have you been in Remission? .

    • @blackknight125
      @blackknight125 ปีที่แล้ว

      @Richelle deJong after I had my prostate removed I went in Remission it been almost a year June 14 2022 however I am on pens and Needles Wondering I'd and when it come back I have a very aggressive type cancer

  • @12superoo
    @12superoo ปีที่แล้ว

    As usual, I am even more confused.
    I already had 20 doses of radiation. Afterwards my PSA was 1.9 and has climbed to 5. in 18 months. I now have spots in "quote" 4 to 5 L Nodes. they now put me on 18 months of depot hormone treatment. My first injection two weeks ago. I do not want to continue with the next 5 by 3 monthly injections.
    I am looking at keto and carnivore diet. I can not see the point of years of toxic unnatural stuff in my body with all the side effects to come.
    How long could I live before I am gone and I wonder how many of those years would be as comfortable as i am this stage of my life. I am 71.

    • @jabster58
      @jabster58 5 หลายเดือนก่อน

      Sad noone even tried to answer you

    • @bojanreljic8310
      @bojanreljic8310 4 หลายเดือนก่อน

      Hello, what is your Gleason score? You can live years on hormon terapy if response is good.

  • @trevorhoskins7643
    @trevorhoskins7643 ปีที่แล้ว

    After chemo and radiation what is the number of the testosterone

  • @rowdyson2654
    @rowdyson2654 ปีที่แล้ว

    I had Gleason 6 and my PSMA PET scan showed a spot in one seminal vesicle and possibly a lymph node alongside prostate gland . What the bloody hell are you on about ?????????????????????????

    • @thomaslehmann5981
      @thomaslehmann5981 11 หลายเดือนก่อน

      Your biopsy probably missed the higher grade cancer. It does happen.