APOE TREM and Microglia in the Pathogenesis of Tau-mediated Neurodegeneration with David Holtzman MD

[@mistahtom]

So in the E4 phenotypes, there’s upregulation of pro-inflammatory genes and downregulation of protective housekeeping genes in microglia 39:28

[@zionayokunnu1086]

If TREME2 limits Abeta seeding, why is PLX before Abeta deposition decreasing it?

[@jyotii1188]

Can u please mention the paper. It will be helpful ...pleaseeeeeee

[@SparksandBubbles]

Please look at work of Dr. Nemechek..... Right this alley