I am so glad I came across your channel. Thank you. Two of my questions were asked by two viewers to which you have answered. Usually most questions are never answered at other channels. Very grateful.
I would like to explain why taking antioxidant supplements can reduce the effectiveness of radiation therapy in cancer patients. Radiation therapy is based on the concept that cancer cells have a significantly higher labile iron pool compared to normal cells (approximately 1000 times higher). When radiation interacts with this iron, it generates reactive oxygen species (ROS) that lead to the death of cancer cells through a process called ferroptosis. Antioxidants work by scavenging these ROS, which can ameliorate the effectiveness of radiation therapy. It's important to note that Artemisinin and high-dose vitamin C also exploit the same mechanism of action in their anti-cancer effects. While antioxidants are beneficial for cancer prevention, individuals with cancer who are undergoing a killing phase using pro-oxidants should refrain from taking antioxidants during that time. This "press-plus" strategy has been proven effective in fighting cancer. During the killing phase, it is recommended to use high-dose vitamin C (as a glycolysis inhibitor) and pure EGCG (Epigallocatechin gallate) not the whole green tea extract as an inhibitor of glutaminolysis (specifically GDH1 inhibition) simultaneously, while maintaining a ketogenic diet. The simultaneous use of these compounds has synergistic effects, effectively depriving cancer cells of their main energy sources. It is crucial to understand the timing and context in which antioxidants and pro-oxidants are used in cancer treatment to maximize their effectiveness. The press-plus strategy has shown promise in starving cancer cells and can be a valuable approach in the fight against cancer. Please note that this information is based on scientific research and should be discussed with healthcare professionals for personalized advice and treatment plans.
Thank you for the discussion. Laboratory-based evidence needs careful interpretation. It should not be used directly onto clinical situations. We have learned important lessons in our trials of antioxidant for cancer prevention or avoidance of cancer treatment side effects. Why Oncologists do not Recommend Antioxidant Supplements? th-cam.com/video/oqwEc1SPdSg/w-d-xo.html
This discussion sounds like it's a discussion during post-cancer treatment. What about use of antioxidants to prevent cancer? This sounds like there is nothing you can really do except hope you don't develop cancer. 😞😢
So during radiation therapy can patient use artemisinin and vit c or not. This is so interesting! And how long after rad. ther. should avoid suplements?
As cancer in the vital organs is always fatal, by giving the anti oxidants if it can reduce some free radicals in the body, better to give. Whether or not helpful. Unfortunately most of the malignant cancer is always fatal
That presumption has been proven incorrect. There is good evidence showing harm rather than benefit of antioxidant use in patients with cancer, regardless of late or early stages.
I would avoid curcumin supplement, but consume curcumin as a food spice. Eating blueberries is fine. Here are two other videos which might help answer your question. How to Enhance the Antioxidant Ability of Blueberries? th-cam.com/video/8_kvs_rs-w4/w-d-xo.html Antioxidant Use may Increase Cancer Risks, What about Antioxidants in Our Foods? th-cam.com/video/C5q5sazHJ4c/w-d-xo.html
There is not enough evidence to support long term benefit of fasting in cancer patients. Most of the randomized trials of fasting tested feasibility and tolerability of the approach, but without generating long term data. It will still require good quality randomized clinical trials to guide clinical application of fasting as a part of treatment for cancer patients. Here is an article from JAMA showing over 13-hour night fasting was associated with lower breast cancer recurrence rate, but without better caner survival or overall survival benefits. jamanetwork.com/journals/jamaoncology/article-abstract/2506710
I have been dealing with metastatic triple-positive breast cancer for almost 8 years. I only take d3 with k2 supplements. I almost started taking an oral hyaluronic acid supplement before doing additional research, where a study found that HA fuels metastasis and helps cancer travel throughout your body. I have an excellent oncologist who had never heard of this study. Doctors are super busy and can't read all available information, so please be your own expert about your type of cancer.
@@vera821I found research studies to be mixed on omega supplements and its relationship to cancer. I think overall it wouldn't be too risky, but I'm pretty reluctant to take most supplements. I have started eating fish 3 times a week and I feel so much better. I just got results from my PET scan and for now the cancer is gone!
Should breast cancer ER Positive survivors consume red meat? I would appreciate your answer knowing full well that this episode was published one year ago. Thank you.
Thank you for the question. I would advocate for a balanced diet. I don't recommend avoiding red meat completely for cancer patients, including with breast cancer. I think the diet should be tailored to nutritional needs, digestive symptoms, and treatment side effects.
So what exactly you want to say should we have omega 3 supplements or not Should we stop having anti oxidants or not. I can’t infer anything from your post
I have a question and thanks for a great video! I have small low grade prostate cancer, will taking 100mg of grape seed extract antioxidant a day be ok? I will stop taking it if it was shown to help the prostate cancer! Thank you
Thank you for your question. I have not seen any randomized clinical trials or good observational evidence about grape seed extract and prostate cancer, so I don't have a definitive answer for you. The argument of grape seed extract is because of rich proanthocyanidins in grape seeds. Proanthocyanidins and beneficial phytochemicals are rich in fruits and vegetables. And there is a good amount of observational evidence supporting benefits of fruit and vegetable consumption in reducing prostate cancer risk and disease progression.
Thank you for your question. Association, even a strong one, does not mean causation. I would interpret it as no clear benefit, but potential harm. However, omega-3 rich foods are linked to lower cancer risks. I would recommend obtaining omega-3 from omega-3 rich foods.
Agree during treatment we shouldn't take supplements can interfere but as a breast cancer survivor I'm cancer free4 years and taking vitd,omega3 and other healthy foid with high antioxidants like:kale,turmeric, cruciferous vegetables, mushrooms, ginger.
@@monikaengel5515 I have not seen any randomized controlled trial evidence supporting benefits of antioxidants in preventing cancer recurrence. Would love to see those articles if you know any author names or article links. Thank you.
@@viorelscrob6391 Vegetables provide important nutrients, but by themselves, the nutrition will not be complete and balanced. Your mom will benefit from a comprehensive nutrition plan that is tailored to her nutritional status, digestive symptoms, and treatment side effects. Hope your mom gets better soon.
These studies are really tossing me around. IF antioxidants were protecting cancer cells. Then the cancer cells would be replicating more rapidly, which in most cases would mean the chemo should have a stronger effect. As the chemo is most often targeting rapidly replicating cells. Thanks do you have any insight on this?
I don't think we fully know the underlying mechanisms. One possibility is that Chemotherapy generates significant oxidative stress and produces a vast amount of oxidants, which can attack cancer cells, but antioxidants can reduce the production of oxidant products and/or counter the actions of those products to reduce chemotherapy efficacy. On the other hand, many antioxidants have dual actions. When they are in the right amount, they act as antioxidants, but when they are in significant excess , they act as oxidants. There is likely much more than that. There was a hypothesis that these oxidative stress products can attack different cellular targets, and make cancer cells less vulnerable to treatments, thus hypothesize that antioxidants can reduce such byproducts of chemotherapy and enhance treatment effects. However, the results of clinical trials have not supported this hypothesis. I’m eager and curious to learn more. Will keep myself updated as much as I can and share with everybody.
I am so glad I came across your channel. Thank you. Two of my questions were asked by two viewers to which you have answered. Usually most questions are never answered at other channels. Very grateful.
I would like to explain why taking antioxidant supplements can reduce the effectiveness of radiation therapy in cancer patients. Radiation therapy is based on the concept that cancer cells have a significantly higher labile iron pool compared to normal cells (approximately 1000 times higher). When radiation interacts with this iron, it generates reactive oxygen species (ROS) that lead to the death of cancer cells through a process called ferroptosis. Antioxidants work by scavenging these ROS, which can ameliorate the effectiveness of radiation therapy.
It's important to note that Artemisinin and high-dose vitamin C also exploit the same mechanism of action in their anti-cancer effects. While antioxidants are beneficial for cancer prevention, individuals with cancer who are undergoing a killing phase using pro-oxidants should refrain from taking antioxidants during that time. This "press-plus" strategy has been proven effective in fighting cancer. During the killing phase, it is recommended to use high-dose vitamin C (as a glycolysis inhibitor) and pure EGCG (Epigallocatechin gallate) not the whole green tea extract as an inhibitor of glutaminolysis (specifically GDH1 inhibition) simultaneously, while maintaining a ketogenic diet. The simultaneous use of these compounds has synergistic effects, effectively depriving cancer cells of their main energy sources.
It is crucial to understand the timing and context in which antioxidants and pro-oxidants are used in cancer treatment to maximize their effectiveness. The press-plus strategy has shown promise in starving cancer cells and can be a valuable approach in the fight against cancer.
Please note that this information is based on scientific research and should be discussed with healthcare professionals for personalized advice and treatment plans.
Thank you for the discussion.
Laboratory-based evidence needs careful interpretation. It should not be used directly onto clinical situations.
We have learned important lessons in our trials of antioxidant for cancer prevention or avoidance of cancer treatment side effects.
Why Oncologists do not Recommend Antioxidant Supplements? th-cam.com/video/oqwEc1SPdSg/w-d-xo.html
This discussion sounds like it's a discussion during post-cancer treatment. What about use of antioxidants to prevent cancer?
This sounds like there is nothing you can really do except hope you don't develop cancer. 😞😢
So during radiation therapy can patient use artemisinin and vit c or not. This is so interesting! And how long after rad. ther. should avoid suplements?
As cancer in the vital organs is always fatal, by giving the anti oxidants if it can reduce some free radicals in the body, better to give. Whether or not helpful. Unfortunately most of the malignant cancer is always fatal
That presumption has been proven incorrect. There is good evidence showing harm rather than benefit of antioxidant use in patients with cancer, regardless of late or early stages.
Is curcumin supplement an antioxidant that should be avoided if one has cancer? What about eating blueberries?
I would avoid curcumin supplement, but consume curcumin as a food spice. Eating blueberries is fine. Here are two other videos which might help answer your question.
How to Enhance the Antioxidant Ability of Blueberries? th-cam.com/video/8_kvs_rs-w4/w-d-xo.html
Antioxidant Use may Increase Cancer Risks, What about Antioxidants in Our Foods? th-cam.com/video/C5q5sazHJ4c/w-d-xo.html
Fasting is very beneficial for cancer patients
There is not enough evidence to support long term benefit of fasting in cancer patients. Most of the randomized trials of fasting tested feasibility and tolerability of the approach, but without generating long term data. It will still require good quality randomized clinical trials to guide clinical application of fasting as a part of treatment for cancer patients. Here is an article from JAMA showing over 13-hour night fasting was associated with lower breast cancer recurrence rate, but without better caner survival or overall survival benefits.
jamanetwork.com/journals/jamaoncology/article-abstract/2506710
@@Dr.WenliLiu Dr. Valter Longo has shown that fasting in cancer patients does show significant benefits. Just google him for more.
I have been dealing with metastatic triple-positive breast cancer for almost 8 years. I only take d3 with k2 supplements. I almost started taking an oral hyaluronic acid supplement before doing additional research, where a study found that HA fuels metastasis and helps cancer travel throughout your body. I have an excellent oncologist who had never heard of this study. Doctors are super busy and can't read all available information, so please be your own expert about your type of cancer.
Why not omega 3
@@vera821I found research studies to be mixed on omega supplements and its relationship to cancer. I think overall it wouldn't be too risky, but I'm pretty reluctant to take most supplements. I have started eating fish 3 times a week and I feel so much better. I just got results from my PET scan and for now the cancer is gone!
Should breast cancer ER Positive survivors consume red meat? I would appreciate your answer knowing full well that this episode was published one year ago. Thank you.
Thank you for the question.
I would advocate for a balanced diet. I don't recommend avoiding red meat completely for cancer patients, including with breast cancer. I think the diet should be tailored to nutritional needs, digestive symptoms, and treatment side effects.
@@Dr.WenliLiu Thank you so much. Greetings from Turkey.
So what exactly you want to say should we have omega 3 supplements or not Should we stop having anti oxidants or not. I can’t infer anything from your post
I recommend obtaining antioxidants from foods, not from supplements.
I have a question and thanks for a great video! I have small low grade prostate cancer, will taking 100mg of grape seed extract antioxidant a day be ok? I will stop taking it if it was shown to help the prostate cancer! Thank you
Thank you for your question. I have not seen any randomized clinical trials or good observational evidence about grape seed extract and prostate cancer, so I don't have a definitive answer for you. The argument of grape seed extract is because of rich proanthocyanidins in grape seeds. Proanthocyanidins and beneficial phytochemicals are rich in fruits and vegetables. And there is a good amount of observational evidence supporting benefits of fruit and vegetable consumption in reducing prostate cancer risk and disease progression.
Thank you so much!
@Integrative Medicine Perspective BS, fruit has sugar and every cancer cell needs it to survive. Think~
Dr L. Must we avoid antioxidants suplements during chemotherapy as well? Thsnk you
Yes. But I think it's beneficial to eat foods naturally rich in antioxidants.
Using omega 3 can make cancer recurrence, is that correct ?
Thank you for your question.
Association, even a strong one, does not mean causation. I would interpret it as no clear benefit, but potential harm.
However, omega-3 rich foods are linked to lower cancer risks. I would recommend obtaining omega-3 from omega-3 rich foods.
Is a protect antioxidant for the cancer. .?
I'm not sure about what you try to ask.
Agree during treatment we shouldn't take supplements can interfere but as a breast cancer survivor I'm cancer free4 years and taking vitd,omega3 and other healthy foid with high antioxidants like:kale,turmeric, cruciferous vegetables, mushrooms, ginger.
@@monikaengel5515 My mom has a ovarian cancer but vegetables don't really help her. ..
@@monikaengel5515 I have not seen any randomized controlled trial evidence supporting benefits of antioxidants in preventing cancer recurrence. Would love to see those articles if you know any author names or article links. Thank you.
@@viorelscrob6391 Vegetables provide important nutrients, but by themselves, the nutrition will not be complete and balanced. Your mom will benefit from a comprehensive nutrition plan that is tailored to her nutritional status, digestive symptoms, and treatment side effects. Hope your mom gets better soon.
You can ALKALIZE YOur body. Eat foods that do.
These studies are really tossing me around.
IF antioxidants were protecting cancer cells. Then the cancer cells would be replicating more rapidly, which in most cases would mean the chemo should have a stronger effect. As the chemo is most often targeting rapidly replicating cells.
Thanks do you have any insight on this?
I don't think we fully know the underlying mechanisms.
One possibility is that Chemotherapy generates significant oxidative stress and produces a vast amount of oxidants, which can attack cancer cells, but antioxidants can reduce the production of oxidant products and/or counter the actions of those products to reduce chemotherapy efficacy.
On the other hand, many antioxidants have dual actions. When they are in the right amount, they act as antioxidants, but when they are in significant excess , they act as oxidants.
There is likely much more than that.
There was a hypothesis that these oxidative stress products can attack different cellular targets, and make cancer cells less vulnerable to treatments, thus hypothesize that antioxidants can reduce such byproducts of chemotherapy and enhance treatment effects. However, the results of clinical trials have not supported this hypothesis.
I’m eager and curious to learn more. Will keep myself updated as much as I can and share with everybody.
Exercise, build muscle. Period End of Story~
What a puppet parrot