in familial retinoblastoma why the other normal allele is being mutated and is it in all/most patients? in other words why second hit happens and how frequent it is?
It's treatable. Using a combination of chemotherapy and local treatment (with cold or laser), 90% of patients are cured and the majority of them also retain eyesight in the affected eye. However, patients with an hereditary RB1 mutation, who survive this pediatric cancer, are at high risk of developing other types of malignant tumors in adulthood.
Hi- retinoblastoma survivor here. While chemotherapy and local treatment are options and may be beneficial depending on the staging of the tumor to preserve some of the eye sight, enucleation (removal of the eye) is also used and how my parents chose to proceed. Enucleation is typically presented as the only way to be absolutely certain the cancer is gone, however it still could spread if margins in surgery are not clear. For those who proceed with enucleation, they are usually fitted with a prosthetic eye to prevent facial drooping. This means they will have the prosthetic eye/glass eye polished and cleaned every few months, as well as new prosthetics made every few years due to growth in the eye socket and degradation of the material used in the prosthetic.
Let me question something do you know where you will go after you die? If not let me say something after you die you can have a choice to either go to hell or heaven see 2000 years ago there was this man named Jesus who died on the cross for our sins and rose alive 3 days later all because he truly loved us he died for us so I question you now do you truly believe in Jesus or do you live for the world turn to Jesus Christ trust in him Christ has way much more to give than the world he loves us turn to Christ
This video is just perfect, I'm a visual learner and now I'll remember this forever 😻 thank you!!
Great presentation...Thank you very much. Kindly consider to upload more BCG, Cyto and Molecular lectures as well.
Very clear explanation and well done video!
Great lecture too the point❤
Great presentation 👍
Great video
Excellent!
Thank you so much
in familial retinoblastoma why the other normal allele is being mutated and is it in all/most patients?
in other words why second hit happens and how frequent it is?
Great video,
Thanks and Keep it up😄
really helpful, thank you!
Please tell me that Diseases is treatable or not?
It's treatable. Using a combination of chemotherapy and local treatment (with cold or laser), 90% of patients are cured and the majority of them also retain eyesight in the affected eye. However, patients with an hereditary RB1 mutation, who survive this pediatric cancer, are at high risk of developing other types of malignant tumors in adulthood.
Hi- retinoblastoma survivor here. While chemotherapy and local treatment are options and may be beneficial depending on the staging of the tumor to preserve some of the eye sight, enucleation (removal of the eye) is also used and how my parents chose to proceed. Enucleation is typically presented as the only way to be absolutely certain the cancer is gone, however it still could spread if margins in surgery are not clear.
For those who proceed with enucleation, they are usually fitted with a prosthetic eye to prevent facial drooping. This means they will have the prosthetic eye/glass eye polished and cleaned every few months, as well as new prosthetics made every few years due to growth in the eye socket and degradation of the material used in the prosthetic.
Did you remove your video on Aicardi syndrome? I can't find it :(
Let me question something do you know where you will go after you die? If not let me say something after you die you can have a choice to either go to hell or heaven see 2000 years ago there was this man named Jesus who died on the cross for our sins and rose alive 3 days later all because he truly loved us he died for us so I question you now do you truly believe in Jesus or do you live for the world turn to Jesus Christ trust in him Christ has way much more to give than the world he loves us turn to Christ
He died , then he was born , well he ain't dead so......
Amen ❤❤❤
Just got done watching the first part on how you get it. Actually, you don't get it. *You're born with it.* That really sucks...