As a human biology graduate from the late 1990s it's fascinating to come back to this interesting topic, of which I have a very hazy recollection. Thank you, Professor Patel.
And a young Historian (Teacher/Researcher). in love since early age with Astronomy, Anthropology, Archeology, Biology, Chemistry, Physics and Xenobiology(Could be the sum of them all). It's suck's to have to choose only one path of study, I LOVE them all. It really sucks having only one short life. The universe, from far way stars, to microorganism and subatomic particles its all too interesting and beautiful. Hope i can live until my 90s with a healthy mind. Greetings from Curitiba, Brazil.
couldn't understand if the ancestor with Ubx expression at T3 had the downstream targets for the morphology of the wing, or instead for the morphology of the haltere. And how could one conclude the ancestor had one or the other, since the ancestor is gone.
12:50 The genes are arranged on the chromosome in the same sequence as their expression from anterior to posterior? Wow. That is so elegant that it is unlikely to be a coincidence.
That's the debate... Can evolution truly produce such elegant forms or not? Perhaps it is too late to tell, we cannot travel back in time. What I believe is the middle ground, that we cannot know whether there is an intelligent designer or not
It's a consequence of the mechanism of recombination that is responsible fir duplicating the gene. Not evidence for the supernatural. There are a few species that have split their Hox clusters through recombination, and do just fine
if the pattern formation starts from anterior to posterior (which I did not yet understand if that is the case or instead if segments are all formed at the same times) then there must be inhibitors or methylated promotors presumably at the hox downstream genes, and once segmentation continues from anterior to posterior end, the closest hox genes which had methylated promotors are demethylated and become active. Maybe there is a gradient from anterior to posterior ends that favor the degree of methylation or any other kind of inhibition of genes within the length of the chromosome.
![[Re:all TREASURE] EP.6 in 방콕ㅣ🚩 쩡캠의 방콕 투어 빵 마이 와이 👍](http://i.ytimg.com/vi/uyFw-nItA_s/mqdefault.jpg)
As a human biology graduate from the late 1990s it's fascinating to come back to this interesting topic, of which I have a very hazy recollection. Thank you, Professor Patel.
Excelent work. I could finally understand how the hox genes expression works
Agustín .López Ortiz how does it work?
A must read: "Endless Forms Most Beautiful: The New Science of Evo Devo" by Sean B. Carrol (Prof. Nipam Patel is cited too)
He gets a mention in Neil Shubin's "Some Assembly Required.." as well
Awesome lecture. You are exciting brazilian students!!
And a young Historian (Teacher/Researcher). in love since early age with Astronomy, Anthropology, Archeology, Biology, Chemistry, Physics and Xenobiology(Could be the sum of them all).
It's suck's to have to choose only one path of study, I LOVE them all. It really sucks having only one short life. The universe, from far way stars, to microorganism and subatomic particles its all too interesting and beautiful.
Hope i can live until my 90s with a healthy mind.
Greetings from Curitiba, Brazil.
couldn't understand if the ancestor with Ubx expression at T3 had the downstream targets for the morphology of the wing, or instead for the morphology of the haltere. And how could one conclude the ancestor had one or the other, since the ancestor is gone.
Iam trying to figure out how to get an embryo to grow wings and gills.
Awesome talk and awesome science
Nice work, keep it going, carry on...
Thank you!
excellent lecture !
12:50 The genes are arranged on the chromosome in the same sequence as their expression from anterior to posterior? Wow. That is so elegant that it is unlikely to be a coincidence.
That's the debate... Can evolution truly produce such elegant forms or not? Perhaps it is too late to tell, we cannot travel back in time. What I believe is the middle ground, that we cannot know whether there is an intelligent designer or not
It's a consequence of the mechanism of recombination that is responsible fir duplicating the gene. Not evidence for the supernatural. There are a few species that have split their Hox clusters through recombination, and do just fine
if the pattern formation starts from anterior to posterior (which I did not yet understand if that is the case or instead if segments are all formed at the same times) then there must be inhibitors or methylated promotors presumably at the hox downstream genes, and once segmentation continues from anterior to posterior end, the closest hox genes which had methylated promotors are demethylated and become active. Maybe there is a gradient from anterior to posterior ends that favor the degree of methylation or any other kind of inhibition of genes within the length of the chromosome.
Thank you sir
Why does the embryo die? Because of the missing A1?
In slide at min 20:31is not a haltere disk, is a third leg disk. Everything else is perfect.
this is the same disk because the halteres are located on the same segments
Can I get the Power Point Presentation of this lecture....?????
The Sushil Mulodia no
A very lucid talk.
Poor mice :(
miserableness
thank you!