Functions of Surfactants in Alveoli

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Video Summary:
This video is on functions of surfactants in alveoli in respiratory system. Alveolar wall is line with fluid. This fluid has surface tension that creates multiple problems. Like due to surface tension on the fluid, alveoli tends to collapse. It makes it harder to inflate the lungs. Second problem is fluid accumulation in the alveoli. As the surface tension tries to decrease surface area or collapse the fluid film, it draws fluid from interstitium into the alveoli. This increases thickness of fluid layer of alveoli. This increased thickness makes it more difficult for respiratory gases to diffuse through it. Third problem is, as per Laplace law, the smaller alveoli produces higher pressure on the air inside the alveoli as compared to the pressure generated in larger alveoli. So smaller alveoli collapses into larger alveoli. This collapsing decreases total surface area available for gas exchange. So such collapsing should be prevented. Surfactants by decreasing surface tension, solves all three problems. They makes it easy to expand lungs or in other words, increase compliance of the lung. Second, they prevent fluid accumulation in the alveoli and third, they prevent collapsing of smaller alveoli into larger alveoli. In the video, all the functions are described with help of animation.
🎞More videos on Respiratory Physiology:
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- Factors Shifting Oxygen Hemoglobin Dissociation Curve: • Factors Shifting Oxyge...
- Oxygen Hemoglobin Dissociation Curve during Exercise: • Oxygen Hemoglobin Diss...
- Transport Of Carbon Dioxide: • Transport of Carbon Di...
- Carbon Dioxide Dissociation Curve: • Carbon Dioxide Dissoci...
- Haldane Effect: • Haldane Effect in Tran...
● Lung Mechanics
- Alveolar Pressure and Pleural Pressure: • Alveolar Pressure and ...
- Surface Tension in Lung Alveoli: • Surface Tension in Lun...
- Surfactants Mechanism of Action: • Surfactants Mechanism ...
- Functions of Surfactants: • Functions of Surfactan...
- Compliance of Lungs: • Compliance of Lungs
- Diseases Affecting Lung Compliance: • Diseases Affecting Lun...
• Ventilation & Dead Spaces in Respiratory Tract: • Ventilation & Dead Spa...
• Lung Volumes and Capacities: • Lung volumes and capac...
• What Determines Lung Volume?: • What Determines Lung V...
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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.

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[@NonstopNeuron]

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Thank you! these two videos （ Surface Tension in Lung Alveoli）clear up my confusion of Surfactants in lung. Best videos among the all net!!!

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[@NonstopNeuron]

Glad you like it. Thank you so much 😊

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@@NonstopNeuron can you please explain how the surfactant can be extracted from a bacterial source without losing it's activity

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[@NonstopNeuron]

Hi NK Nakavil. I am happy to see that our videos are helping you. And yes, We will always have animations where needed. If you really want us to grow, please support us by sharing words about the channel and website as much as you can. We need it so much as we are very early in our journey. Thank you.

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[@NonstopNeuron]

Thank you. Yes, this is an old video. I have made some improvements in audio since then.

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I use multiple prgrams. There are many steps and each step require different programs. I use RemNote, Affinity designer, PowerPoint, Audacity, Blender etc.

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[@nausadansari6836]

What are the surfactant

[@khadijah3343]

what does collapse of liquid mean at 1:31?

[@NonstopNeuron]

it means the collapse of liquid-air interface. due to surface tension, the interface surface area tends to get smaller and smaller. just like a rubber band. when it's stretched, it tends to collapse. The liquid-air interface is like rubber band. It tends to collapse due to surface tension.

[@khadijah3343]

and why does collapse of liquid draw more fluid into the alveoli?

[@NonstopNeuron]

Due to attraction between water molecules.! You can also think this way: vacuum is created between alveolar wall and alveolar liquid as the liquid collapse. So liquid from interstitium fills in that vacuum. There is also some collapse of alveoli due to that vacuum. But there is also some pulling of water from interstitium. I hope you are getting it.

[@nishawaskle4934]

density is directly proportional to surface tension so how did it possible
5:49

[@NonstopNeuron]

Can you elaborate the doubt

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