Thanks for watching! If there's a particular supplement or dietary approach for chronic pain that you'd like to know more about, leave me comment down below.
Enjoyed your presentation Very clearly done Question Is there a supplement out there that has the five ingredients you mentioned here ? Love to hear back if you can Thx do much
Thanks so much! The first thing to do would be to determine the source of the problem. What's causing the foot to "fall asleep" - is it a circulatory issue, a neurological issue, is it positional or activity-related. Lots of questions need to be answered before an appropriate course of treatment can be determined.
Thanks Kalkeys! Four capsules/day provides a full therapeutic dose of all the nutrients in Joint Relief. I like to take 2 in the first part of the day and 2 more before bed on an empty stomach.
Dr. Whitten: I have arthritis & a Baker cyst on my LEFT knee, When I go to the gym, I ride the stationary bikes & I peddle backwards. Does that help my knees, like walking backwards? Also, if I use the stair master, will that help my knees too?
Hi Yoni, I'm wondering if you have come across a pain medication called Conolidine - made from the plant Tabernaemontana divaricate. Apparently it's been used in Chinese and Ayurvedic medicine for ages.
Great question, Betsy! The short answer is yes, and here are some specifics: - Undenatured Type 2 Collagen has demonstrated the ability to induce tolerance, effectively reducing joint pain and swelling in RA subjects. pubmed.ncbi.nlm.nih.gov/12837047/ - PEA for the treatment of RA - pubmed.ncbi.nlm.nih.gov/34056884/ - Boswellia Serrata & RA - pubmed.ncbi.nlm.nih.gov/31041173/ - Honokiol & RA - pubmed.ncbi.nlm.nih.gov/26339358/ I wasn't able to find any studies on French Maritime Pine Bark Extract and RA
Supplements are, as the name implies, a great supplemental strategy and they're very effective. However, the primary strategy for something sciatica should be physical medicine/rehab directed at the source of the nerve compression.
Thank you for sharing these great supplements, I can attest to type II collagen for knee pain but I'm confused about nitric oxide and Honokiol. My NO is low (91) and have been trying to increase it to get better blood flow to the brain (white matter problems) with citrulline..., am I creating inflammation? What's the ideal NO level?
That's fantastic, Micheline! Undenatured type II collagen is pretty amazing stuff! The short answer is "no". Nitric oxide (NO) is a vasodilator. The researchers in the honokiol study that I shared used it as one marker for an acute inflammatory process (because after an injury, the body wants to bring more blood to the damaged area and NO is part of that process).
Could you expand a little bit about the collagen? I have been taking Great Lakes bovine collagen peptides ( type I and III). What is special about type II ?
Good question, Bill! To be clear, type 1 & 3 collagen peptides are awesome and have a ton of benefits when taken regularly, in therapeutic doses. In fact, I did an entire video just on the benefits of that type of collagen. But, undenatured type II collagen is a different animal altogether. The retention of its' normal structure (being undenatured) enables it to interact with the immune system and trigger a series of anti-inflammatory / healing cascades within the body. To capture all the benefits, I make sure to take both types.
Great question, Donna! The short answer is yes, and here ares some specifics: Undenatured Type 2 Collagen has demonstrated the ability to induce tolerance, effectively reducing joint pain and swelling in RA subjects. pubmed.ncbi.nlm.nih.gov/12837047/
PEA for the treatment of RA - pubmed.ncbi.nlm.nih.gov/34056884/ Honokiol & RA - pubmed.ncbi.nlm.nih.gov/26339358/ Boswellia Serrata & RA - pubmed.ncbi.nlm.nih.gov/31041173/ I wasn't able to find any studies on French Maritime Pine Bark Extract and RA
I am not an expert on Naltrexone and I would encourage you to direct your questions about it to your doctor / pharmacist. I do know that this drug is classified as an "opiate antagonist". Apparently, it works by preventing the brain from experiencing things like: pain relief & feelings of well-being. I believe it's used primarily to help people overcome addiction to opioids.
@@painfixprotocol Quite a few folks in the CFS/FM community take it, some with good results others not so much, or have side effects such as sleep issues. Didn’t help me, I’ll try some of your suggestions, thanks Yoni.
Every one of the ingredients in Joint Relief has an impeccable safety record. But, for anyone taking prescription medications, it's always best to check with your doctor / pharmacist before adding any nutritional supplement to your daily regimen.
The half life of P.E.A. is only 25 minutes. To get the most from a dose, supplementing with an MAO inhibitor like Oat Straw will lengthen the half life.
Thank you for commenting! Those are good suggestions! There seems to be quite a few things that can influence the half life of this nutrient - including the form of PEA (micronized / ultramicronized). I am a bit curious as to what study it was that showed a 25 minute half life? The only reference I've seen to a half life that short was a 2015 study done on rats. This paper discusses a 12 hour half life in human subjects. www.alzdiscovery.org/uploads/cognitive_vitality_media/Palmitoylethanolamide-Cognitive-Vitality-For-Researchers.pdf
@@painfixprotocol I don't remember but I can speak from experience. I took an extreme dose (15 grams) once because I mistook PEA for a different DIY preworkout ingredient. The effects were extreme, to the point that it had me worried but they didn' t last for much more than 30 minutes. The closest thing I can relate it to, is like when you nebulize prednisone. It affected my breathing and had me on "high alert".
My mom has thalamic central post stroke pain down her entire left side for the last 20 years-will this significantly help or would you have other recommendations-she has a motor corte stimulator implant which has failed and pharmaceuticals do not do much for her? She also has vascular parkisonism.
It's a good question, Chris. There's some interesting research on PEA on both stroke and neuroinflammation. pubmed.ncbi.nlm.nih.gov/26055231/ and pubmed.ncbi.nlm.nih.gov/26706245/. I strongly recommend talking to your mom's doctor / pharmacist before adding any nutritional supplement.
I appreciate this information, but if there are amazing plant pain reduction supplements out there why keep encouraging people to use animal products. We really need to leave animals alone. Live and let live!
Yes, many great supplements are derived from plants. But, if we can put the ethical and moral arguments (many of which I agree with) aside for a second, the fact is that human beings are omnivores and many of the nutrients we require can only be obtained from animal sources - Eicosapentaenoic acid (EPA) is one example.
Great question, Donna! The short answer is yes, and here ares some specifics: Undenatured Type 2 Collagen has demonstrated the ability to induce tolerance, effectively reducing joint pain and swelling in RA subjects. pubmed.ncbi.nlm.nih.gov/12837047/ PEA for the treatment of RA - pubmed.ncbi.nlm.nih.gov/34056884/ Honokiol & RA - pubmed.ncbi.nlm.nih.gov/26339358/ Boswellia Serrata & RA - pubmed.ncbi.nlm.nih.gov/31041173/ I wasn't able to find any studies on French Maritime Pine Bark Extract and RA
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Thanks for watching! If there's a particular supplement or dietary approach for chronic pain that you'd like to know more about, leave me comment down below.
Restless legs.
Thanks@@karenkukurin5078! I'm adding that to my list of future video topics.
Enjoyed your presentation
Very clearly done
Question
Is there a supplement out there that has the five ingredients you mentioned here ?
Love to hear back if you can
Thx do much
So glad you enjoyed it. Joint Relief contains all of the nutrients mentioned in this video and more - store.painfixprotocol.com/products/joint-relief/
Have you reviewed Boswilla, turmeric, MSM, hyaluronic acid and omega 3?
Yes, I have @littlevoice_11! And you can see my review clicking "PLAY VIDEO" on this page: store.painfixprotocol.com/products/joint-relief/
Absolutely appreciate your responding to so many individuals, VERY RARE! Thank you for bringing up so much scientific background as well.
I am also interested in learning more about SI joint
Thanks Eric! There's more to come!
Yoni always has helpful advice! Any suggestions for a leg or foot that falls asleep...over and over again?
Thanks so much! The first thing to do would be to determine the source of the problem. What's causing the foot to "fall asleep" - is it a circulatory issue, a neurological issue, is it positional or activity-related. Lots of questions need to be answered before an appropriate course of treatment can be determined.
Hi Yoni. Great sounding product. What is the recommended dosage of this product?
Thanks Kalkeys! Four capsules/day provides a full therapeutic dose of all the nutrients in Joint Relief. I like to take 2 in the first part of the day and 2 more before bed on an empty stomach.
Dr. Whitten: I have arthritis & a Baker cyst on my LEFT knee, When I go to the gym, I ride the stationary bikes & I peddle backwards. Does that help my knees, like walking backwards? Also, if I use the stair master, will that help my knees too?
Hi Yoni, I'm wondering if you have come across a pain medication called Conolidine - made from the plant Tabernaemontana divaricate. Apparently it's been used in Chinese and Ayurvedic medicine for ages.
I have heard of it. Curiously, I have not been able to find any clinical trials measuring the effects of conolidine. If you know of any, please share.
What particular brand do you recommend for PEA? So many out there, would like a quality brand.
Great question, the most important thing is to go with something micronized to help enhance absorption.
Where do you find this stuff
Joint Relief is available here: store.painfixprotocol.com/products/joint-relief/
Will this work on RA, not just osteoarthritis?
Hi. I’m impressed with your confidence and knowledge on pain. Do you think this product will work on restless legs?
Thank you, Karen. Restless leg syndrome is something different - I plan to make a video on that topic in the near future.
I’ll be anxiously waiting. It seems to be a multi-prong issue.
Yes,@@karenkukurin5078. Chronic issues like that are very often multifaceted.
Would these nutrients be useful for rheumatoid arthritis? Thanks
Great question, Betsy! The short answer is yes, and here are some specifics:
- Undenatured Type 2 Collagen has demonstrated the ability to induce tolerance, effectively reducing joint pain and swelling in RA subjects. pubmed.ncbi.nlm.nih.gov/12837047/
- PEA for the treatment of RA - pubmed.ncbi.nlm.nih.gov/34056884/
- Boswellia Serrata & RA - pubmed.ncbi.nlm.nih.gov/31041173/
- Honokiol & RA - pubmed.ncbi.nlm.nih.gov/26339358/
I wasn't able to find any studies on French Maritime Pine Bark Extract and RA
What would you recommend for sciatica? My dad is in so much pain
Supplements are, as the name implies, a great supplemental strategy and they're very effective. However, the primary strategy for something sciatica should be physical medicine/rehab directed at the source of the nerve compression.
Thank you for sharing these great supplements, I can attest to type II collagen for knee pain but I'm confused about nitric oxide and Honokiol. My NO is low (91) and have been trying to increase it to get better blood flow to the brain (white matter problems) with citrulline..., am I creating inflammation? What's the ideal NO level?
That's fantastic, Micheline! Undenatured type II collagen is pretty amazing stuff! The short answer is "no". Nitric oxide (NO) is a vasodilator. The researchers in the honokiol study that I shared used it as one marker for an acute inflammatory process (because after an injury, the body wants to bring more blood to the damaged area and NO is part of that process).
Could you expand a little bit about the collagen? I have been taking Great Lakes bovine collagen peptides ( type I and III). What is special about type II ?
Good question, Bill! To be clear, type 1 & 3 collagen peptides are awesome and have a ton of benefits when taken regularly, in therapeutic doses. In fact, I did an entire video just on the benefits of that type of collagen. But, undenatured type II collagen is a different animal altogether. The retention of its' normal structure (being undenatured) enables it to interact with the immune system and trigger a series of anti-inflammatory / healing cascades within the body. To capture all the benefits, I make sure to take both types.
You mention osteo arthritis several times. Are these also effective for RA?
Great question, Donna! The short answer is yes, and here ares some specifics: Undenatured Type 2 Collagen has demonstrated the ability to induce tolerance, effectively reducing joint pain and swelling in RA subjects. pubmed.ncbi.nlm.nih.gov/12837047/
PEA for the treatment of RA - pubmed.ncbi.nlm.nih.gov/34056884/
Honokiol & RA - pubmed.ncbi.nlm.nih.gov/26339358/
Boswellia Serrata & RA - pubmed.ncbi.nlm.nih.gov/31041173/
I wasn't able to find any studies on French Maritime Pine Bark Extract and RA
How about Low Dose Naltrexone? What are your thoughts?
I am not an expert on Naltrexone and I would encourage you to direct your questions about it to your doctor / pharmacist. I do know that this drug is classified as an "opiate antagonist". Apparently, it works by preventing the brain from experiencing things like: pain relief & feelings of well-being. I believe it's used primarily to help people overcome addiction to opioids.
@@painfixprotocol Quite a few folks in the CFS/FM community take it, some with good results others not so much, or have side effects such as sleep issues. Didn’t help me, I’ll try some of your suggestions, thanks Yoni.
❤️💖🙏❤️💖
Cheers!
CHRONIC Leg Pain ❤😢
Sorry to hear about your pain. Do you know what's causing it?
Where can we purchase these products ?
Thanks for asking, K.L. Here's the link: da790.isrefer.com/go/jointrelief/PFP/
Are these safe for someone taking blood thinners eg edoxaban.
Every one of the ingredients in Joint Relief has an impeccable safety record. But, for anyone taking prescription medications, it's always best to check with your doctor / pharmacist before adding any nutritional supplement to your daily regimen.
Is your product available in Australia without paying individual shipping from Nth America?
While we are able to ship products anywhere in the world, production and fulfilment is based in the United States.
The half life of P.E.A. is only 25 minutes. To get the most from a dose, supplementing with an MAO inhibitor like Oat Straw will lengthen the half life.
Thank you for commenting! Those are good suggestions! There seems to be quite a few things that can influence the half life of this nutrient - including the form of PEA (micronized / ultramicronized). I am a bit curious as to what study it was that showed a 25 minute half life? The only reference I've seen to a half life that short was a 2015 study done on rats.
This paper discusses a 12 hour half life in human subjects. www.alzdiscovery.org/uploads/cognitive_vitality_media/Palmitoylethanolamide-Cognitive-Vitality-For-Researchers.pdf
@@painfixprotocol I don't remember but I can speak from experience. I took an extreme dose (15 grams) once because I mistook PEA for a different DIY preworkout ingredient. The effects were extreme, to the point that it had me worried but they didn' t last for much more than 30 minutes. The closest thing I can relate it to, is like when you nebulize prednisone. It affected my breathing and had me on "high alert".
My mom has thalamic central post stroke pain down her entire left side for the last 20 years-will this significantly help or would you have other recommendations-she has a motor corte stimulator implant which has failed and pharmaceuticals do not do much for her? She also has vascular parkisonism.
It's a good question, Chris. There's some interesting research on PEA on both stroke and neuroinflammation. pubmed.ncbi.nlm.nih.gov/26055231/ and pubmed.ncbi.nlm.nih.gov/26706245/. I strongly recommend talking to your mom's doctor / pharmacist before adding any nutritional supplement.
I have had CPSP for a year. I cannot imagine 19 more years of this 😢
I appreciate this information, but if there are amazing plant pain reduction supplements out there why keep encouraging people to use animal products. We really need to leave animals alone. Live and let live!
Yes, many great supplements are derived from plants. But, if we can put the ethical and moral arguments (many of which I agree with) aside for a second, the fact is that human beings are omnivores and many of the nutrients we require can only be obtained from animal sources - Eicosapentaenoic acid (EPA) is one example.
All are good. As soon i could buy them i will tell you. Thank you dr ionni! @alcira8
Thank you, Alcira!
Have you reviewed Boswilla, turmeric, MSM, hyaluronic acid and omega 3?
Yes, I have! And you can see my review clicking "PLAY VIDEO" on this page: store.painfixprotocol.com/products/joint-relief/
You mention osteoarthritis several times. Are these also effective for RA pain?
Great question, Donna! The short answer is yes, and here ares some specifics: Undenatured Type 2 Collagen has demonstrated the ability to induce tolerance, effectively reducing joint pain and swelling in RA subjects. pubmed.ncbi.nlm.nih.gov/12837047/
PEA for the treatment of RA - pubmed.ncbi.nlm.nih.gov/34056884/
Honokiol & RA - pubmed.ncbi.nlm.nih.gov/26339358/
Boswellia Serrata & RA - pubmed.ncbi.nlm.nih.gov/31041173/
I wasn't able to find any studies on French Maritime Pine Bark Extract and RA