Spotlight on Migraine - Episode 16 - The New CGRP Blocking Migraine Treatments
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- เผยแพร่เมื่อ 15 มิ.ย. 2024
- Neurologist Dr. Stewart Tepper explains how the new, "designer" CGRP blocking migraine treatments work, how they are delivered and what to expect for efficacy. These medications come in two different types - gepants and monoclonal antibodies. Dr. Tepper's presentation was recorded in June 2018, after the first of these medications became available to patients in the U.S.
If you support improved access to the best and safest treatments, let your voice be heard. Sign your name to a petition urging healthcare payors to provide better access to migraine treatments. Help us reach 50,000 signatures by December 31, 2020. Sign at www.change.org/MigrainePetition
This podcast is sponsored in part by Alder BioPharmaceuticals and Teva Pharmaceutical Industries.
*The contents of this podcast/video are intended for general informational purposes only and do not constitute medical or legal advice; the content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. The Association of Migraine Disorders does not recommend or endorse any specific course of treatment, products, procedures, opinions, or other information that may be mentioned. Reliance on any information provided by this content is solely at your own risk.
Cost of Emgality in Australia $987.00 a month no Medicare no concessions. How on earth can anyone afford these drugs?
Valuable presentation. God bless scientists and doctors.
I have been using Amovig for two months with over a 75% reduction of my migraines! I have suffered for decades with migraines, with almost no relief trying sumatriptans and some relief with the severity using Botox. Treatment has been only minimally successful treating each episode with Norco and ibuprophen. The results from Amovig has been nothing short of miraculous for me!
Jen Ocean how has it been since? It worked for me for 2
Months and now it’s worse than ever before
A M A Z I N G presentation. Informative, easy to understand and very well presented. Thank you very much.
This is amazing information! I wish I would have listened to this when it first came out! Thank you so much for this helpful information. Great presentation!
I was put on Aimovig but had to discontinue because it raises blood pressure. My Doctor had all her patients stop the medication. Today Aimovig warns that the med will/may raise your BP.
Tremendous info, presented very clearly.
He is the best =) Was the first doctor to ever help me with my migraines years ago. I was so sad when he relocated from Seattle
All the way from Republic of Ireland Filipino. Many thanks
When will this be available in Europe? This could restore my life!
GREAT and clear information,..could we get an UPDATE?????? This is 4 years old.
Dr Teppers my Doc.
You are lucky!! He was mine until he moved to the east coast. He is the best!!
A very Good & encouraging News for all the Migraineurs..... Hope these medicines are able to prevent Chronic & Episodic bouts of migraines.
Ajovy is working well for me. It's cut frequency by nearly 60%.
I have tried aimovig injection and after 7 days l experience uncontrollable HTN severe headache numbness on face jaw
back of my neck . I was in the hospital they did CT scan and wnl. They say they want cortisone but this also make my BP uncontrollable
now they want me to do botox but I am afraid it might be worsen my Bp.
I'm in Canada is it covered on odsp
I didn’t catch on to the medication overuse or “rebound” thing he was talking about. Can someone explain?
Dr.Nedal Barakat
greeting
this pathophysiology could not explain many points related to migraine these are
- why migraine in most of patients is unilateral ?
-why it is related to menstruation pregnancy and abortion ?
-why migraine is more in females than males with ratio 2:1?
- why migraine rear in younger children and fade out at the age of 65 years?
-why we do have acidosis in cerebral blood circulation during migraine ?
- why patients experience diuresis , falling sleep and thriving for sweet foods ?
-as well could not explain the episodic type of headache ?
hope that i can have an answer for these question
Available in Scotland since April on the nhs. Gp can't prescribe. Has to be neurology. On waiting list for an appointment to discuss the medication.
8:20 the very important part
My daughter has had for 2 months severe headache none stop ct sca,mri, have been done and all fine but the pain is there drs don’t find what’s wrong
Is it available in Canada?
Dose it work for patients who had neck trauma causing migraines?
I tried everything available
Botox
Nerve blocks
Most types of triptans, Maxsalt works sometimes
Natural treatments
Chinese medicine
Preventive, like, sandomigraine, amitriptyline, beta blockers, keep hydrated, blood sugar seblized, physical therap, healthy diet,
Sinuses surgery
Eyes and teeth regularly checjed by doctors,
What else can I do?
My life is normal, no more than an average person stress, life is not perfect.
I to have tried tablet medication for chronic migraine.
Mostly the tablet drugs like amitriptyline.
There is different cgrp injections. From what i read ajovy has less side effects compared to emgality.
What are you using now for your migraines?
Aimovig did not work after 12 months Emgality has caused chronic constipation and I mean chronic along with a huge weight gain and depression. But .... it decreased my 6 migraines a week to 3 . If the side effects were not so bad I'd continue. I'm at 15 kilo weight gain so that's enough for me to stop.
What meds are you on now for the chronic migraines? Only meds i find to work are the triptans.
However, triptans arent preventatives. Not taken daily. Destroys liver and maybe other body organs.
Triptans constrict blood vessels and known to have side effects related to heart and respiratory area. Not suitable for people with heart and stroke patients.
If triptans was safe for daily use, would be the cure for chronic migraines now.
Cgrp is a 50/50 i think. Works some, doesnt for some.
These migraine drugs make you gain weight hard. Since i been on these drugs, i gained alot of weight.
Emgality cut my migraine days by 90%, but I gained 14lb, was constipated, and had horrible weals and furious itching. I took a long break. I'm now using Ajovy, with less but still significant migraine reduction, and weight gain of only 5lb. The best way to control the histamine reaction - for me - is to take 2 antihistamines 30 minutes before the shot, and have the shot in the back of the arm. Then I go to bed for the rest of the day.
Had to quit Aimovig. The side effects were unbearable. Rather have migraines instead.
Ajovy is the same. The next for me is Emgality. I hope that one works. If not... then... Sh$t🤯
What are the side effects?
I was on Aimovig after 4 months my neurologist pulled me off of that drug and put me on Emgaity it's been 3 months now and I think they're actually worse My second neurologist looking for one more that can help me.
Xylocaine then 2 weeks later Botox are an absolute miracle for 6 months without ANY migraine !!!
I'm on night one. Living hell . I want it out of my system...
So, I'm in the throes of a horrible migraine, and looking for more information on CGRP Suppressors, and click on this one. BOOM!!! Some asshole beating on a drum so loudly I have to get out of bed and run to Alexa and rip the plug out of the wall to stop the pain. Seriously?? Stupid, stupid, stupid.
What if your allergic to Imitrex ?
All Imitrex and similar triptans family have a very dangerous side effect. They induce a vasoconstriction while during migraine you have a vasodilation in the brain.Unfortunately the vasoconstriction with Imitrex and any Triptans occur also in the heart.Coronary spasm crises occur with Triotan.That is why they are highly dangerous.
Play this video at 1.25% speed because he speaks too slowly. Comes over well at that speed.