This is so helpful! Thanks. I'm taking some MRI grad classes, and these videos definitely help to solidify key ideas before heading into a lecture that would otherwise totally baffle me. I will confess, though, that I find the music throughout a bit distracting. Anyway -- thanks for the time and effort you put into this! It is a massive help.
I'm glad it helped! I definitely learn a lot myself putting them together. You're not the first to tell me about the music. The whole 3D animation and video production process has been a learning experience in and of itself. Because of constructive criticism like yours, I've added and subtracted some audio and video elements over the years to hopefully make the presentations more relevant and succinct. Promise to back off of the distracting background noise going forward! Thanks for the feedback and good luck with your studies.
@@DoctorKlioze I imagine it's a great way to learn! They say teaching is the best way to solidify things. And your animations really add a lot -- the visual plays a huge role in making the info accessible! I went on to the DTI video after watching this one and noticed the music was much quieter! Love a creator who is receptive to feedback (esp as internet people are not always nice about it). Cheers!
Man this video really cleared things up for me regarding the difference between DWI and ADC, and why discrepancies between them is important. I just couldn't understand what the difference was before!
Thanks for the video! I just add this explanation of why infarct appears as a decreased ADC and increased signal in DWI: "In the setting of acute cerebral ischemia, if the cerebral blood flow is lowered to 10 ml/100gm/min, the cell membrane ion pump fails and excess sodium enters the cell, which is followed by a net movement of water from the extracellular to intracellular compartment and cytotoxic edema. Diffusion of the intracellular water molecules is restricted by the cell membranes. The restricted diffusion results in a decreased ADC and increased signal intensity on diffusion-weighted images."
The Cartesian coordinate schematic is utilized due the orientation of the gradient system of MR systems , x,y, and z, the three planes diffusion restriction are measured.
After watching MANY videos on the subject, this is the first one to mention the three cartésien plains. The whole time I'm thinking "How the heck do they get an image out of that!? In 3-D no less!" Now it's starting to make a little more sense.
So CSF with higher B values will have a low signal because with a long enough dephasing and rephasing magnetic gradient CSF with its isotropic diffusuion will be just pushed way too out of phase to give any signal. Proportionatly lower B values may give some more signal with CSF and more shine through, while b0 has no de and rephasing magnetic gradients, so it will essentially just be T2 CSF intensity and very sensitive to any shine through. Is this assumption correct? Also, what is the difference between a b0 and an actual T2 image? Could You in theory skip the b0 if you have a T2 and just use it as b0 instead? Excellent video btw!!
Here's a question for you. Since T1 relaxation dumps heat into the patient, can you localise this effect within a tumour and use it therapeutically? It would be nice to fry tumour cells without harming the patient, and not exposing him or her to X rays!
Interesting concept! The only difficulty I can see is defining a homogeneous 3D magnetic field that basically encompasses the tumor itself and leaves the surrounding tissues unharmed. Then the resonant RF energy would only affect the protons in the tumor itself. Figure it out and I'll probably see you heading to Oslo to collect your Nobel Prize!!
Diffusion is important because it describes the failure of water to transport across a cellular membrane, due to a pathological state, that is not clearly elaborate here.
I do not have a web site. I simply post the videos to this channel as I get them done. I should put together a website and possibly split the videos out by category. I'll see what I can do. Thanks!
I've tried that with other videos however, with these complex topics, viewer retention is an issue. For instance this particular video has an average view time of 5:29 which is about 40% of the total. With the new social media mindset, brevity seems to be king! If you can't state your case in less then 10 minutes, your audience gets board! Thanks for the suggestion, however.
@@DoctorKlioze yeah i know that but its very diiffcult portion that i was asking for that may be u can share link in discription who wants to read it completely
For to do the wavelet transform or Function Wave i am not requiere the complex number or Fourier series. Just I need the new methodoly I discovered.I left this video to compare: th-cam.com/video/3Ebvypj577E/w-d-xo.html
best videos ever on MRI. pls post some more especially principles of MR angiography (Time od flight, phase contrast). thank u so much.
We need more please, I highly appreciate this massive work.
This is the best video covering diffusion that I've seen on youtube!
Best video available on TH-cam regarding MRI basics and dwi ..gr8 way of demonstrating the concept
The best explanation of diffusion tensor imaging I have seen. Thanks for preparing this elegant video.
I find your images showing precessing neutrons much easier to understand than most other videos I've seen.
This is so helpful! Thanks. I'm taking some MRI grad classes, and these videos definitely help to solidify key ideas before heading into a lecture that would otherwise totally baffle me. I will confess, though, that I find the music throughout a bit distracting.
Anyway -- thanks for the time and effort you put into this! It is a massive help.
I'm glad it helped! I definitely learn a lot myself putting them together. You're not the first to tell me about the music. The whole 3D animation and video production process has been a learning experience in and of itself. Because of constructive criticism like yours, I've added and subtracted some audio and video elements over the years to hopefully make the presentations more relevant and succinct. Promise to back off of the distracting background noise going forward! Thanks for the feedback and good luck with your studies.
@@DoctorKlioze I imagine it's a great way to learn! They say teaching is the best way to solidify things. And your animations really add a lot -- the visual plays a huge role in making the info accessible!
I went on to the DTI video after watching this one and noticed the music was much quieter! Love a creator who is receptive to feedback (esp as internet people are not always nice about it).
Cheers!
Many thanks to you John and the all guys that made this precious video.
even though its a complex concept, your explanation has made it crystal clear... thanks a lot
Man this video really cleared things up for me regarding the difference between DWI and ADC, and why discrepancies between them is important. I just couldn't understand what the difference was before!
Best video on mri I have seen till date...
This is very nice video. It make me understand more about these MRI sequences. Thank you very much!!
This video is GREAT!!!! Thank you for your valuable work!!!!
best video about DWI, helpful for every grade of knowlege in MRI.
Well laid out, very concise, and nice summary of the important points to bring it home
That is out of this world 😍 got to love particle physics xxx
Thanks for the video! I just add this explanation of why infarct appears as a decreased ADC and increased signal in DWI:
"In the setting of acute cerebral ischemia, if the cerebral blood flow is lowered to 10 ml/100gm/min, the cell membrane ion pump fails and excess sodium enters the cell, which is followed by a net movement of water from the extracellular to intracellular compartment and cytotoxic edema. Diffusion of the intracellular water molecules is restricted by the cell membranes. The restricted diffusion results in a decreased ADC and increased signal intensity on diffusion-weighted images."
This was like an epiphany to me. Thank you so much
You're very welcome!
The Cartesian coordinate schematic is utilized due the orientation of the gradient system of MR systems , x,y, and z, the three planes diffusion restriction are measured.
After watching MANY videos on the subject, this is the first one to mention the three cartésien plains. The whole time I'm thinking "How the heck do they get an image out of that!? In 3-D no less!" Now it's starting to make a little more sense.
Pretty amazing video,music helps a lot .
stop the music i cannot concentrate
4:56 "The exact MOMENT" - I see what you did there!
Now I understood how DWI works.
great videos. really helped me in a job interview. thanks
As has been noted, great job Dr. Klioze. Thx.
(Off to find the Diffusion Tensor Imaging video...)
very good and explanatory tutorial!!!
many thanks Dr on this magnificent video.
So CSF with higher B values will have a low signal because with a long enough dephasing and rephasing magnetic gradient CSF with its isotropic diffusuion will be just pushed way too out of phase to give any signal. Proportionatly lower B values may give some more signal with CSF and more shine through, while b0 has no de and rephasing magnetic gradients, so it will essentially just be T2 CSF intensity and very sensitive to any shine through. Is this assumption correct? Also, what is the difference between a b0 and an actual T2 image? Could You in theory skip the b0 if you have a T2 and just use it as b0 instead?
Excellent video btw!!
Doctor, this is great. Thanks.
Beautifully explained
Great video .. Thanks Doctor
Thank you so much. This now makes more sense in my head. Would you be able to touch up on the b values as well by any chance? Thanks again
Great video! Thanks for your help!
Please make video on other mri sequence too 🙏
Thank you for the video! Are you going to add one on DTI as well?
Plz cut down the music, it's annoying !!
That will help better focus!!
really helpful to understand the DWI
Good job!
Made it so clear..thanks doc
Nice job
thanks a million. great video
Great video, thanks.
Very Helpful..Thank You.. Need Some more..
Great job👍👍
Very helpful, thank you!
Here's a question for you. Since T1 relaxation dumps heat into the patient, can you localise this effect within a tumour and use it therapeutically? It would be nice to fry tumour cells without harming the patient, and not exposing him or her to X rays!
Interesting concept! The only difficulty I can see is defining a homogeneous 3D magnetic field that basically encompasses the tumor itself and leaves the surrounding tissues unharmed. Then the resonant RF energy would only affect the protons in the tumor itself. Figure it out and I'll probably see you heading to Oslo to collect your Nobel Prize!!
Music choice changed my mood 👌😂
Excellent. Thank you
Diffusion is important because it describes the failure of water to transport across a cellular membrane, due to a pathological state, that is not clearly elaborate here.
Thanks sir.... Great video
The explanation is clear but the concept is bizarre, just little difficult to wrap my head around it
Thank you so much
Really helpful!
Why didn't I find this before!!!
Great music but please lose the music!!!
This is outstanding! Please keep the videos coming
Do you have a website where this information is published? How can I reference this appropriately?
I do not have a web site. I simply post the videos to this channel as I get them done. I should put together a website and possibly split the videos out by category. I'll see what I can do. Thanks!
Thank you.
you're cool. like really cool
Thanks a lot
Gosh.. i feel this is a soo good video about physics.. But still cant get...
Try to make videos larger to completely clear all concepts in one video
I've tried that with other videos however, with these complex topics, viewer retention is an issue. For instance this particular video has an average view time of 5:29 which is about 40% of the total. With the new social media mindset, brevity seems to be king! If you can't state your case in less then 10 minutes, your audience gets board! Thanks for the suggestion, however.
@@DoctorKlioze yeah i know that but its very diiffcult portion that i was asking for that may be u can share link in discription who wants to read it completely
Also, what program do you use to create your animations?
RayDream Studio and 3DS Max
So this is when the machine starts playing tetris?
thanks
Thankyouuuuu
Wow!
lose the music. very distracting
😊🤩
Mark for myself 9:23
🙏🙏🙏🙏
For to do the wavelet transform or Function Wave i am not requiere the complex number or Fourier series. Just I need the new methodoly I discovered.I left this video to compare:
th-cam.com/video/3Ebvypj577E/w-d-xo.html
Great videos (please ease up a little on the corny music >.
Good Grief, that background music is so annoying!
plz speak in Hindi video