AMYLOIDOSIS: Part 1: Definition, Historical aspects & Properties of Amyloid

In this part 1 of "amyloidosis" i have described the definition, historical aspects and properties of Amyloid. Visit ilovepathology.com / for more topics in Pathology!
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AMYLOIDOSIS 1
Is a condition associated with number of inherited and inflammatory disorders
In which There is deposition of Predominantly Extracellular fibrillar proteins RESULTING IN Tissue damage & functional compromise
These are Aggregates of MISFOLDED proteins and are insoluble.
historical aspects:
“amylim” a latin word means “starch”
Matthias Schleiden a German Botanist was the first to use the term “amyloid” in botany, for starch, referring to“starch-like”.
German pathologist Rudolf Virchow (1804 - 1881) applied it in the medical literature in 1854.
used the word “Amyloid” to describe some deposits in nervous system which showed the same color reaction with iodine and sulfuric acid, i.e. a change from brown to blue, typical to starch
In the later years it was found that the chemical nature was unrelated to starch but proteins!
Yet.. The name “amyloid” still remains
Probably because of Virchow was considered as one of the most valued scientists of his time
In the later years it was found that the chemical nature was unrelated to starch but proteins!
Amyloid proteins: Properties
Amyloid is not a single entity
More than 20 different proteins can aggregate to form fibrils.
The mechanisms of formation are different.
Therefore amyloidosis should not be considered as a single disease… rather, a group of diseases with deposition of similar appearing proteins

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[@ilovepathologyVijayPatho]

Thank you very much. Glad you liked it. Do circulate :-)

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[@anshusen3439]

very helpful video on such a complicated topic for mbbs students, thank you very much sir

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[@futuredoctor4786]

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[@drpooja1327]

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[@adnan.q.753]

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[@mappthub941]

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Amyloidosis pptx

[@mybookismylife.2798]

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[@ilovepathologyVijayPatho]

Thank You very much :-)

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Planet Ayurveda’s approach to Amyloidosis treatment is amazing. I feel like a new person

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Thank u so much sir. Pls do more videos on systemic pathology.

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[@ilovepathologyVijayPatho]

Thanks . Glad you liked them . Good luck

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Nice lecture

[@priyajha1384]

Please make more videos sir
It is a excellent summery of robbins

[@srushtikatore454]

very informative ...thank u very much

[@kasturivlog8727]

Thnk

[@shivanichhabra1166]

Thanks for this wonderful video. My mother was suffering from Amyloidosis for last years. We visited many hospitals and doctors but didn’t get good results. Then I visited to planet ayurveda and they gave her some Ayurvedic medicines and she got well after using that .

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Best!

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Fantastic video. Minor comment in minute 7:25 you mention that APP increase, not always, negative APP decrease.

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Please post more videos of more chapters.

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Amyloidosis pptx

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It is very concise and clear notes. Most needed. Thank you sir

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Have you covered whole pathology in your videos???

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nice but try to slow down a little....so we can assimilate properly

[@obiwan922]

kindly someone help me with this concept. .... ''when we say beta pleated sheet formation , do we mean the structure of each single protein (within the amyloid fibrils; i assume amyloid fibrils are composed of group of proteins) is beta pleated sheet. Or the fibril as a whole forms beta pleated sheet. " ..i actually didnt understand the beta pleated sheet idea in amyloid formation. from the basic idea, I just know beta pleated sheet is one of the secondary structure of any single protein. Thanks.

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My father got diagnosed with AL amyloidosis ...m looking for s amyloidosis specialists in india ... kindly guide me

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SIR PLS MAKE A VIDEO ESPECIALLY ON SYSTEMIC LUPUS ERYTHEMATOSUS

[@ilovepathologyVijayPatho]

It’s done already
Check the latest videos

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I thing that the information share for the death rate is wrong in your video so please check it once and rectify it if u can . Thank you .

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Why did you post other chapters

[@itzhabeeba9491]

Mattias scleiden I heard this name second time...one in inter biology and same here

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Is there any treatment for macular amyloidosis. my skin become dark now and its spreading

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Mine too

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Can you provide pdfs? Helpful ppts

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❤

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Sir are you following ramdas nayak?

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Please answer 🙏

[@ilovepathologyVijayPatho]

By all means..general pathology lectures are for all..the concepts will be understood better..

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Curcumin capsules from planet ayurveda are very helpful in amyloidosis disease

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Sir i have lichen amyloidosis on my both leg since last 15 years.
How can i get rid from it

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Do you have IBD?

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@@jannatulasrar3553 do u have this to

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👍🏻👍🏻👍🏻

[@jagrajsingh6494]

I was diagnosed with Lichen Amyloidosis. My whole body got covered with rashes and papules and I was having severe itching. I was rushed to the hospital and was started on antihistaminics, but no relief was there. Next day, I came back to home and was very much tensed due to this. One day I was surfing for the internet and mistakenly opened one site named as Planet Ayurveda. I ordered Amyloidosis care pack online and used it for 3 months. It gave me much relief in my symptoms.

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😍😍😍

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amyloidosis care pack helps to reduce this type of problems. my sister was struggling with same problems, then she'd use planet ayurveda products and now she's ok. i think you also have to try these products with the help of consultations by dr vikram chauhan.

[@akhily6026]

Dil sulphuric acid

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Is it from robbins 😉

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Ok thanks for mentioning

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Sir avaaj thoda kam pad raha hai thoda jor se bolo na please baki video ekdum ready hai .,...

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ಇಂಪ್ರೆಸ್ಸಿವ್

[@lordjim24]

Why are all these videos done by Indians with strong accents? Can barely understand.

[@abinashpadhy4457]

My father got diagnosed with AL amyloidosis ...m looking for s amyloidosis specialists in india ... kindly guide me