PT245 - Robin Carhart-Harris - Psychedelics, Entropy, and Plasticity
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- เผยแพร่เมื่อ 28 ก.ย. 2024
- In this episode, Michelle and Kyle interview head of the Centre for Psychedelic Research at Imperial College London, Founding Director of the new Neuroscape Psychedelics Division at UCSF, and psychedelic research legend, Robin Carhart-Harris.
He discusses what inspired his milestone entropic brain/REBUS model research and how psychedelics drop the assuredness we've established through our "prediction machine" brains, contemplates how science hasn't really answered the question of why we fall ill, and dives into plasticity, trauma, germ theory, and the sensitivity of orchids vs. dandelions. He also talks about HPPD, the need to concretize abstract experiences, DMT, how being somewhat of a psychedelic celebrity has affected him, and his thoughts on Compass Pathways and the recent "land grab" and patenting stories that have been making the rounds recently.
Carhart-Harris and his team are currently researching anorexia, psychedelic sub-states (like looping), group ayahuasca use, nature connectedness, and conflict resolution (with MAPS).
www.psychedelicstoday.com
I have taken LSD and Psilocybin and they are both very similar in their effects. LSD is an 8 to 10 hour experience, Psilocybin is a 4-6 hour experience.
It's always interesting to listen to Dr Carhart-Harris. I also found his perspective on his fame and the fickleness of it to be interesting and funny as well. Thanks for asking that not so obvious question.
a non SF episode with video, nice!
There will be more in the future!
This was absolutely fantastic. Thank you, PT! 💜
50:48
Timestamps?? 😂
Great podcast!!
HPPD doesn’t last. The visual distortions do not last… they go away as your brain heads back into a biochemical equilibrium… what can last are changes to understandings and associations… HPPD is likely to last longer the stronger the dose is… but personally I have not seen tests or data on any of this… it’s just personal experience… subtle changes are difficult for the person to be aware of… as qualia states are inherently hard to compare as they are fleeting and only a condensed representation of the moment can be meta analyzed by the inser.
Thanks for conducting the interesting inverview with Dr. Carhart-Harris.
He and his team is performing important research. What is surprising though is that he seems to be thinking along the lines of the "green meme" (Spiral Dynamics), i.e. relativism and inclined to neo-leftist ideas (multiculturalism, relativism, socialism, climate change, black lifes matter, vegetarien diet, inclusion, labeling non-mainstream opinions as "conspiracies", materialism in combination with a kind of neo-esoteric view, feminism, gender studies, digitalization, transhumanism, etc.). His take on vaccination is also quite shocking. He seems to be not aware that the Covid vaccines are actually a very bad idea and which many acientists providing warning against their use. I bet he will label them as "anti-vaxxers". His thinking is also quite in line with the modern leftist mainstream opinion. I am sure he would not be able to really understand my critique. His planned stay in California (a hot-spot for the neo-leftist ideology) will consolidate and support his current worldview, I predict.
No serious doctor has an issue with the vaccines. We are doing 4th shots in the UK now and have seen no problems with it.
I'm glad they asked about the entities and the relation to brain processes. I'm an artist with a background in psychology and in my (limited) experience, I got the feeling that we have purpose but that applying meaning is a very human thing. I ran into entities that made it pretty plainly aware that they were parts of my own subconscious. I haven't taken the time to pinpoint each part of my most recent experience, but my mind is definitely pointing me in the right direction. I feel that these images are how we perceive complex processes in that disconnected space. It's so interesting. Also, when it comes to NDE, I've experienced 3 in my life. The first I don't remember, but the second was due to lack of oxygen and I was taken to that same bright cloudy foggy headspace you can sometimes get into on lower doses of Psilocybin. Another time there was no imagery, just a profound emptiness, completely dark (lack of energy). I'm doing relatively well now and while these experiences can be challenging, I think that the benefits far outweigh the discomfort (i'm sensitive and also have tummy issues). So excited to learn more. Stay curious.
... Listening to this man, I feel like a child learning how to talk...
Has robin written a book about his research?
Not that I know of. He probably should! $$$
@39:30 this is an issue I am concerned with, particularly when considering how this treatment modality scales to the clinic. Research currently skirts the ethics around stopping treatment that has been shown to be of benefit to a range of mental ill-health issues after 2 sessions in a country where the same treatment is currently illegal. The ethics shift in 2023 in oregon, and when the fda approves a drug assisted therapy that will likely take place over more than 2 sessions. The issue of real or imagined trauma and how to integrate such an experience that feels both unreal and remembered can create issues that wont be discovered until after a host of challenging and complex cases emerge.
The compounds are incredible and important, but the way in which they are being researched is also of interest and could inform a more general model of healing that is based upon the therapeutic alliance and the boldness to remove the top down regulator and fully go through your issues with support.
I hope the general public doesn't miss the value of the healing relationship within which the psychedelic experiences are taking place in the research getting impressive results (spare the NEJM article which compared psychedelic assisted therapy to placebo assisted therapy and escitalopram which only showed moderate favorability after a bayesian reanalysis awaiting publication).
... Thank you... Very substantive and beautiful..
Robin, thanks for your generosity as well as great work.
To avoid ambiguity, the term "entropy" doesn't apply to psychedelic effects as a scientific descriptor, but is used as a generic term to categorize their nature, particularly in the breakdown of the ego and the DMN. By aptly encapsulating his findings, the term helped transmit Dr. Carhart-Harris' work to the psychiatric community. Th result has been to open one of the most promising avenues of research in all of psychedelic psychiatry.
🦍🔥🦍