RNA interference/RNA silencing/RNAi mechanism.

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  • เผยแพร่เมื่อ 9 พ.ย. 2024

ความคิดเห็น • 368

  • @mkouser5020
    @mkouser5020 5 ปีที่แล้ว +60

    Thank you sooo muchhhh u made RNAi very easy for me i was so tensed and when i watched this i was likeeee how should i thank uu♥️

  • @shaikimran1132
    @shaikimran1132 4 ปีที่แล้ว +122

    How many of you are irritated by byjus and vedantu ads

    • @malikovais5162
      @malikovais5162 4 ปีที่แล้ว

      Meeeeeeee🙋🙋🙋🙋🙋🙋🙋

    • @studentdigitalzone5048
      @studentdigitalzone5048 4 ปีที่แล้ว

      Me too

    • @dr.4176
      @dr.4176 4 ปีที่แล้ว +1

      Mee tooo 🙋‍♀️🙋‍♀️🙋‍♀️🙋‍♀️🙋‍♀️

    • @whysoserious6581
      @whysoserious6581 4 ปีที่แล้ว +2

      I'm irritated of unacademy ads!

    • @Vaishnavi__555
      @Vaishnavi__555 2 ปีที่แล้ว

      Mee

  • @vivekpal3820
    @vivekpal3820 หลายเดือนก่อน +1

    There to here
    Ua re inspiration for us

  • @user-mt7hs5sx6z
    @user-mt7hs5sx6z 4 ปีที่แล้ว +5

    Bst explaination ....u make me crystal clear about dis topic ...✌️

  • @mdwasi8575
    @mdwasi8575 4 ปีที่แล้ว +7

    You are also best for master level .God bless you,thank a lot.

    • @mdwasi8575
      @mdwasi8575 4 ปีที่แล้ว

      👍👍👍👍

  • @suja605
    @suja605 3 ปีที่แล้ว +9

    Thankyou so much sir. I wasn't understanding this particular topic in my class. Now I am all clear. I am so grateful. :)

  • @abdulaahd992
    @abdulaahd992 4 ปีที่แล้ว +2

    Thnk u very much sir

  • @smaranikapadhi7280
    @smaranikapadhi7280 3 ปีที่แล้ว +3

    Mind-blowing explanation

  • @Dev_Sisters
    @Dev_Sisters 4 ปีที่แล้ว +1

    Very nice vidio sir bhot easy way me samjhaya hai aapne or ncert ko cover kerne wala vidio hai thanx sir

  • @AkashKumar-tc5vj
    @AkashKumar-tc5vj 5 ปีที่แล้ว +3

    this channel is not for avg. student...
    so complex explanation......

  • @kuldeeparora2768
    @kuldeeparora2768 4 ปีที่แล้ว +7

    thanks for making this topic to get into my head...

  • @Divyasingh-pc4sb
    @Divyasingh-pc4sb 3 ปีที่แล้ว +5

    It was a amazing lecture 👍

  • @neerajarora1474
    @neerajarora1474 3 ปีที่แล้ว +1

    You are the best

  • @deleeppatel8987
    @deleeppatel8987 6 ปีที่แล้ว +37

    those who dislike. this wonderfull video
    may be they do not aware about
    translation

    • @abolikandalkar3953
      @abolikandalkar3953 4 ปีที่แล้ว +4

      Dislikes are bcoz there are so many facts that are unexplained

    • @Preettractorrohtak
      @Preettractorrohtak 4 ปีที่แล้ว

      @@abolikandalkar3953 yes u r ryt

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 ปีที่แล้ว +2

      Some poeple came here in search of stuff like RISC, DICER, Argonaught proteins , etc.

    • @adilharis3277
      @adilharis3277 4 ปีที่แล้ว +2

      @@navinsawesomeanddivineacco4221 ya.... Me...

  • @GurshaanGaming
    @GurshaanGaming 2 ปีที่แล้ว +1

    Oh yes ,I was looking for this.

  • @thefeveroffreefire6220
    @thefeveroffreefire6220 10 หลายเดือนก่อน +1

    Thank you so much sir,
    I was very confused about this topic from a month and now it is crystal clear..🤩

  • @ashishsoni4586
    @ashishsoni4586 4 ปีที่แล้ว

    Nice explaning

  • @meerakundariya9062
    @meerakundariya9062 3 ปีที่แล้ว +2

    Thank you sir
    I understood very well ☺️✌️✌️👍👍👍👍

  • @anujgupta8447
    @anujgupta8447 6 ปีที่แล้ว +10

    I want to ask you
    that you tell ds complementry rna come from any virus having rna as genetic material then how this rna is complementary to ss rna of melodigyne incognitia . Please reply

    • @SajitaKu
      @SajitaKu 6 ปีที่แล้ว +2

      I'm also confused at that point..good question bro

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 ปีที่แล้ว +4

      Its actually much more complicated than what its sylabus. You see the DS RNA is then made into a Silencing Complex. One of the RNA strand is made into "Guidestrand? which will guide the silencong complex silence the mRNA of the virus while the other strand is degraded. Thats the very simple explaination of how the silencing happens. There is also other things like the Argonaught protein and the RISC thingie. See this video, it explains all that. But you dont have to worry abput it all if ypu are here for NEET or Boards. :) m.th-cam.com/video/cK-OGB1_ELE/w-d-xo.html

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 ปีที่แล้ว +1

      Its actually much more complicated than what its sylabus. You see the DS RNA is then made into a Silencing Complex. One of the RNA strand is made into "Guidestrand? which will guide the silencong complex silence the mRNA of the virus while the other strand is degraded. Thats the very simple explaination of how the silencing happens. There is also other things like the Argonaught protein and the RISC thingie. See this video, it explains all that. But you dont have to worry abput it all if ypu are here for NEET or Boards. :) m.th-cam.com/video/cK-OGB1_ELE/w-d-xo.html

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 ปีที่แล้ว

      Its actually much more complicated than what its sylabus. You see the DS RNA is then made into a Silencing Complex. One of the RNA strand is made into "Guidestrand? which will guide the silencong complex silence the mRNA of the virus while the other strand is degraded. Thats the very simple explaination of how the silencing happens. There is also other things like the Argonaught protein and the RISC thingie. See this video, it explains all that. But you dont have to worry abput it all if ypu are here for NEET or Boards. :) m.th-cam.com/video/cK-OGB1_ELE/w-d-xo.html

    • @ramakrishnareddy1967
      @ramakrishnareddy1967 4 ปีที่แล้ว +1

      It is there in akash module entire process explained for your doubt but it is not necessary

  • @hirakjyotideka1082
    @hirakjyotideka1082 4 ปีที่แล้ว +1

    Sirjee ek baat batau, nematodes during infection apne genes chor deta hein plant cells ke andar??? Wo virus thode hi hein..

  • @karibasappar7391
    @karibasappar7391 4 ปีที่แล้ว +1

    super

  • @suchitajoshi8461
    @suchitajoshi8461 5 ปีที่แล้ว +1

    Sir please mera ek doubt hai rnai ko lekar ....apne jo btaya lecture mai vo sab samjh aya..but ncert mai ek line di hai jisme likha hai ki parastie will not survive due to rna interference... please isko clear krr dijiye.....vo specific protein konsa hai jiske na milne se nematode survive nhii kr pa rha hai..please sir..reply!!!!!!!!!!!!

  • @MehenazSultana
    @MehenazSultana 5 ปีที่แล้ว +5

    Sir agrobacterium se gene Kya tobacco plants K growth K suruwath mein dete Hain...

  • @vlogsjunction5763
    @vlogsjunction5763 5 ปีที่แล้ว +13

    Thankyou for clearing my doubts nd yess u got ur new subscriber and a person to like nd share each vdos of urs bcz i know if tht vdo helps me thn othrs definitely will... ❤

  • @pawansoni5446
    @pawansoni5446 6 ปีที่แล้ว +1

    You are the best biology teacher

  • @vishalpatidar4383
    @vishalpatidar4383 4 ปีที่แล้ว

    Nice teaching sir

  • @Harshsharma-qj4bu
    @Harshsharma-qj4bu 3 ปีที่แล้ว +2

    Thanks our big brother to help us in such a beautiful explanation

  • @sarim5593
    @sarim5593 5 ปีที่แล้ว +1

    Why sense and antisense strand produced in host not in pathogen..

  • @jyotisnatanwar446
    @jyotisnatanwar446 6 ปีที่แล้ว +2

    Thank you such nice knowledge by your veido

  • @dailygs655
    @dailygs655 3 ปีที่แล้ว +3

    Thank you so much for such a descriptive lecture about RNAi before that I think tht wow how hard to learn it is and after watching this I am like how so sily 😂😂🙈✌💫...

  • @Prathamkumar007
    @Prathamkumar007 6 ปีที่แล้ว +1

    From where the tranposons come.

  • @sourabhgamerpubg8055
    @sourabhgamerpubg8055 5 ปีที่แล้ว +7

    Bro ur teaching is really effective continue it .....😍😍😍😍. ....
    and may u reach a good no. Of students....and help them to crack meet/aiims....

  • @ashwiniashwini2110
    @ashwiniashwini2110 5 ปีที่แล้ว +1

    befor watching the video only i will like it because i know it will be good

  • @yogitanegi8049
    @yogitanegi8049 6 ปีที่แล้ว +1

    very good video sir

  • @akankshamishra12thb77
    @akankshamishra12thb77 ปีที่แล้ว

    Jb complementary rna already double stranded hai toh wo nematode kai mrna se kyu bind kre ga .. nematode kai mrna toh free hai uske trna aa-aa kr protein chain bna denge ..

  • @gulshanhaque3837
    @gulshanhaque3837 3 ปีที่แล้ว +6

    thank you so much for such a great explanation ❤️

  • @sailatkuri7598
    @sailatkuri7598 3 ปีที่แล้ว +1

    Wher does mRNA get silenced in plant cell or nematode cell

  • @raghibakbar2821
    @raghibakbar2821 6 ปีที่แล้ว +3

    I am tuoght about it in my bio class but even though i could not understand it but now its clear

  • @farhadjaan7863
    @farhadjaan7863 3 ปีที่แล้ว +1

    Thanks sir.....

  • @aviratsingh653
    @aviratsingh653 3 ปีที่แล้ว +1

    Thankyou 🙏🙏🙏

  • @priyasatapathy5945
    @priyasatapathy5945 5 ปีที่แล้ว +3

    thank u..sir ..i never understood this so cleary ..before u taught this

  • @jeevanduttsharma9601
    @jeevanduttsharma9601 4 ปีที่แล้ว +2

    Thanks 😘 😘😘 😘😘 😘😘 😘😘 😘😘 😘😘 😘 luv u sirrr 🙏🙏 🙏🙏 🙏

  • @Preettractorrohtak
    @Preettractorrohtak 4 ปีที่แล้ว +8

    U has not explained the complete process like
    RISC

  • @jagdishsad7617
    @jagdishsad7617 3 ปีที่แล้ว +1

    Thanks bhaiya

  • @raghavagarwal7703
    @raghavagarwal7703 6 ปีที่แล้ว +1

    Sir,if we are inhibiting the formation of protiens or enzymes will it affect the quality of the tabbaco or the protiens that the tobbaco plant is making does'nt related to the tabbaco formation. It might be possible that the protien that the tobbaco plant is synthesising is necessary for the production of tabbaco,if the protien is have some role in it and we are inhibiting that protien then it must be a major drawback and hence will reduce yield production. Plz answer my que. I am confused about this thing.Thankyou.

  • @bioblast2961
    @bioblast2961 4 ปีที่แล้ว +1

    When double standard RNA is made inside that little bit, then inside the human body or inside the plant body, why it will make a single stand and if it is still there then how will it be connected with single standard and other double standard

    • @kuldeeparora2768
      @kuldeeparora2768 4 ปีที่แล้ว

      RNA is always single stranded that means initially it is present in single strand in our body and this single stranded RNA will further result for the formation of proteins.....
      If want to stop the protein synthesis so we will induce another RNA intentionally from outside... because of which RNA becomes double stranded and only single stranded RNA can form protein and now it is in double stranded form so there will be no protein synthesis....

  • @tasleemshaik193
    @tasleemshaik193 4 ปีที่แล้ว +1

    Yeh joh cimplementary rna joh ki kisi virus k dwra laya jaata hy kya iska koi defect nhi hota???? I mean doesn't it harm any way????
    Sir I hope u will look into my doubt pllz

  • @akashsandhu3846
    @akashsandhu3846 6 ปีที่แล้ว +1

    Please make a video on BT cotton

  • @pinkeshgurjar4262
    @pinkeshgurjar4262 3 ปีที่แล้ว

    Nice explanation sir g

  • @madhurima3208
    @madhurima3208 5 ปีที่แล้ว +16

    Please add some more information. Thank you for clearing my doubt 😃😃

  • @tadarkoya3466
    @tadarkoya3466 4 ปีที่แล้ว +1

    Thx sir😎😎😎

  • @samridhipunj3916
    @samridhipunj3916 6 ปีที่แล้ว +1

    sir what is sense and antisense rna?????

  • @jaskiratgill6253
    @jaskiratgill6253 6 ปีที่แล้ว +1

    Nice explanation

  • @darkwarrior1417
    @darkwarrior1417 3 ปีที่แล้ว +1

    Bhai ,
    What is the difference between ANTISENSE RNA TECHNIQUE AND RNAi

  • @priyajoshi5646
    @priyajoshi5646 2 ปีที่แล้ว

    ❤️ thanku sir..
    Some hr later I have my biology exam

  • @ayshasiddiqui413
    @ayshasiddiqui413 3 ปีที่แล้ว +2

    Thanku very much !! U just nailed it understood in one go !

  • @anandhuvijayan7027
    @anandhuvijayan7027 6 ปีที่แล้ว +2

    you are a powerful teacher , KEEP IT UP thank u

  • @gurpreetsingh-om6ly
    @gurpreetsingh-om6ly 5 ปีที่แล้ว

    Brilliant

  • @khushboodhiman6877
    @khushboodhiman6877 4 ปีที่แล้ว +1

    Thank you for this awesome lecture

  • @PriyaYadav-vk9uy
    @PriyaYadav-vk9uy 6 ปีที่แล้ว +1

    superb

  • @yashchaudhary3228
    @yashchaudhary3228 6 ปีที่แล้ว +1

    sir can u plzz explain the agrobacterium more cleary

  • @shahnawazhossain2740
    @shahnawazhossain2740 4 ปีที่แล้ว +3

    If totally protein synthesis stopped , then how the tabacco plant will survive??

    • @shraddhashetty206
      @shraddhashetty206 3 ปีที่แล้ว +2

      The total protein synthesis of the plant doesn't stop....only the gene(mRNA) of the nematode is inactivated and prevented from forming it's respective proteins which cause the disease.

  • @ravibishnoiravibishnoi8191
    @ravibishnoiravibishnoi8191 5 ปีที่แล้ว +1

    Thanks sir 👍 👌

  • @neerajarora1474
    @neerajarora1474 3 ปีที่แล้ว +1

    You are legend

  • @princearya412
    @princearya412 5 ปีที่แล้ว +1

    It's really very helpful 👍

  • @amarnathbehera1455
    @amarnathbehera1455 6 ปีที่แล้ว +1

    Fantastic

  • @bharathfittness9183
    @bharathfittness9183 3 ปีที่แล้ว +1

    Best techer i ever sown..✨

  • @d7smmhaske868
    @d7smmhaske868 4 ปีที่แล้ว

    Fabulous bhayya

  • @manjuagarwal4100
    @manjuagarwal4100 5 ปีที่แล้ว +16

    Outstanding.🤗🤗🤗🏅🥇🥇🏅🏅🥇🥇

  • @its_vikram_07
    @its_vikram_07 6 ปีที่แล้ว +1

    Excellent teaching sir......

  • @anaghasubbaraya8842
    @anaghasubbaraya8842 6 ปีที่แล้ว +2

    it was really a good lecture bhai...thank you

  • @mahejabeen906
    @mahejabeen906 5 ปีที่แล้ว +1

    How we provide or from where we provide double strand rna

    • @jyotizine4047
      @jyotizine4047 5 ปีที่แล้ว

      Same doubt

    • @AtoofaHilal
      @AtoofaHilal 3 ปีที่แล้ว

      That may be frm any infection caused by virus having rna genome...since normally our body doesn't hv ds rna

  • @karthikeyanvenugopal8074
    @karthikeyanvenugopal8074 4 ปีที่แล้ว

    What is transposon sir?

  • @SunitaDevi-vw9fe
    @SunitaDevi-vw9fe 5 ปีที่แล้ว +5

    Sir nice lecture but it is so time consuming

  • @andemmamatha3967
    @andemmamatha3967 4 ปีที่แล้ว

    Good explanation....

  • @aditisri8470
    @aditisri8470 4 ปีที่แล้ว +1

    loads of thank you sir

  • @ranipabbineedi3708
    @ranipabbineedi3708 4 ปีที่แล้ว

    Badiya bhaiya😊

  • @sankalpbawankar1392
    @sankalpbawankar1392 5 ปีที่แล้ว

    Nice video sir👍👍👍

  • @shubhampaikrao3951
    @shubhampaikrao3951 4 ปีที่แล้ว +1

    Thanks brother 👍

  • @zoyokhan1844
    @zoyokhan1844 5 ปีที่แล้ว +2

    Thanks a lot sir your help from all students

  • @aloneabhi1077
    @aloneabhi1077 3 ปีที่แล้ว

    Super sir

  • @ashishgadekar3260
    @ashishgadekar3260 7 ปีที่แล้ว +3

    Sir u are the best... Sir after this lesson start ecology..

  • @sadanvs5072
    @sadanvs5072 6 ปีที่แล้ว +1

    Sir what is sense and antisense rna

  • @siddharthaverma18
    @siddharthaverma18 5 ปีที่แล้ว

    U said Transposons(Jumping Genes) are the source for the other strand of RNA......but Transposons are DNA sequences not RNA sequence....so how can a DNA strand bind a RNA strand??
    Apart from this u have told anything about the introduction of Nematode specific genes using Agrobacterium Vectors.....and the production of sense and anti-sense RNA in the host cell through that introduced DNA..!!
    Kindly Explain!!!

    • @dr.4176
      @dr.4176 4 ปีที่แล้ว

      Yes u r right that transposons are dna sequences ....let me explain that if u have read the earlier chapter of molecular basis of inheritance , there we have seen that dna sequences are converted to mRNA by the process of transcription. I hope now u can understand that when transposons are introduced then by the process of transcription it will produce the complementary RNA strand and then it will bind with the existing rna strand and then it will make double stranded rna strand .

  • @GunjanR516
    @GunjanR516 2 ปีที่แล้ว

    God level teaching... Thank uh

  • @shailendradwivedi7080
    @shailendradwivedi7080 6 ปีที่แล้ว

    Too good

  • @Rahilkhan-sx5zz
    @Rahilkhan-sx5zz 5 ปีที่แล้ว +1

    Keep it up sir.

  • @snekasneka2833
    @snekasneka2833 4 ปีที่แล้ว +1

    Hi sir... I have a small doubt.. From where the complementary ds rna comes... Please reply to this message

  • @noyssam
    @noyssam 4 ปีที่แล้ว +2

    How complementary ds rna silence the ss rna?

    • @navinsawesomeanddivineacco4221
      @navinsawesomeanddivineacco4221 4 ปีที่แล้ว +3

      Hey it reality its a lot more complex than this. The Ds RNA will then help form something called a Silencing complex with a couple of proteins. One of the strands act as a guide Strand while the other is degraded and this guide strand will search for a specefic recognition sequence of the Nematode mRNA and the silencing complex will then silence it. Heres a video where it explains RNAi. You dont need to know for exam though though. They wont ask about the RISC complex or Argonaught proteins. :)m.th-cam.com/video/cK-OGB1_ELE/w-d-xo.html

  • @sumanpal3380
    @sumanpal3380 5 ปีที่แล้ว +2

    thank you sir for clearing my doubts

  • @shahnazbegum1463
    @shahnazbegum1463 6 ปีที่แล้ว +2

    Thanks sir for coming back on screen 👍👍👍👍👍

  • @srirammuddineni3388
    @srirammuddineni3388 3 ปีที่แล้ว

    Good explanation bro it helps us

  • @someshjaiswal6750
    @someshjaiswal6750 5 ปีที่แล้ว +1

    amazing sir

  • @himanshichoudhary2061
    @himanshichoudhary2061 4 ปีที่แล้ว

    Thanks

  • @world_explore
    @world_explore 6 ปีที่แล้ว +1

    Sir u are so good

  • @akshita9918
    @akshita9918 4 ปีที่แล้ว +2

    Thank u soooo much sir this really helped me a lot

  • @irtizque9596
    @irtizque9596 3 ปีที่แล้ว

    The mRNA silenced belongs to eukaryote?

  • @nishanthsugumar7867
    @nishanthsugumar7867 5 ปีที่แล้ว

    Doing good job

  • @nidhi878
    @nidhi878 4 ปีที่แล้ว +6

    Thanks sir for this wonderful lecture

  • @sabinayeasmin9214
    @sabinayeasmin9214 4 ปีที่แล้ว

    U r doing a great job......