Amine Inversion - Flipping in Amines || IITian Explains 🔥
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- เผยแพร่เมื่อ 5 ก.พ. 2025
- Amine inversion is basically quantum tunneling effect where the nitrogen atom protons tunnel through a potential energy barrier that allows the molecule to invert its shape.
In the second row of the periodic table, elements have relatively small differences between the size their s- and p-orbitals. Therefore, the orbitals of NR3
can go from sp3 to sp2 with relatively little energy increase, so an amine can become planar and then reorient with the inverted stereochemistry. The same occurs with carbanions. Similarly, for oxonium cations do this, as well, and I would even guess that it would happen more quickly due to oxygen's smaller size.
The reason we don't see this with NF3 is because orbitals with more p character are more affected by induction, so the highly electronegative fluorine atoms would lose electron density during inversion, which would be energetically unfavorable (to the point that it doesn't occur readily).
Chiral phosphines do not invert because the size difference between s- and p-orbitals for larger atoms is greater, so converting 𝑠𝑝3 orbitals to 𝑠𝑝2 would require much contraction and, therefore, more energy than for the analogous amine.
Thanks
MKA Sir
You are three times gate qualifier ,have got best teaching awards,and teaching whole day in unacademy and pursuing phd from Fukushima University....after all of these you are giving the whole world a free access to your awesomely organized lectures....Your hardship and mentality always encourage me sir, You are the Legend Mka
SIR You are one of the greatest teachers i have encountered online and the method to clear the topics is just awesome...hats off to your work sir and cool hair though...
Guruji I have a doubt.
It is given in to compare basic strength
p)CH3- q)NH2- r)OH- s)F-
Taking into consideration the inversion I thought the answer would be q>p>r>s .
But in MS Chouhan Book it's given p>q>r>s. Please tell me which one is correct.
I think P>Q>R>S as here it is on basis of donor atom
Also sir said that this Umbrella inversion occurs in sp3 compounds with 1Lone pair but in NH2- there are 2 Lone pair so it won't happen here !!
@@nilaykumarsingh1962 thanks so much 😂 but now no need. I am already in IIT 😂
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@@nilaykumarsingh1962 IIT Madras Meta 🥰
That was just awesome.... jitne billion baar ye flipping hoti h vitne hi like dena chahti hu iss vedio ko!!!!💕🖤❤️🥀🎉🌈🌈🌈🔥🔥🔥🔥🔥
Bahut khushnasib hain hum kyunki hum us sadi main rehte hain jahan aap jaisa teacher humein padata hain
We are the luckiest to have u as our mentor...thanks a lot sir
Maja aya gya sir subah uthte hai apka class 👌👌👌👌👌👌👌👌👌👌👌👌
wow sirji, aap regular ho gaye.... ab maza aayega, saara game change ho jaayega ab.....thnx sir
Sir aap ek no. Padhate hai.Aap sir ek dum basic se advance le jate hain topic ko
Sir , Sir gazab hogya!!!!!....
i Read the description of this video ,What!! - Quantum Tunneling ,,,,,▪️◻️🔅▪️ WoW !! Just WoW!! 🎉
Organic With So much fascination 🔲🏆🎆Sir U are walking Book Type Person
Wait---- walking book ? 🤔
No Walking Books ☺️✌️⚡
Yesterday I was solving some GOC from Book . Most questions were done except the inversion of amines . And today the lecture came. Thanks for this lecture.🥳🥳🥳😎😎.Hats off
were u solving MSC..?
@@itzzkushagra ofcourse
Your Knowledge is tremendously Awesome.
Mja aa jaata h..aapko sunkar Guruji 😇
I must admit that you Sir, have the best quality content on TH-cam! Thank you!
Glad you enjoy it!
Thank you sir, the last question you covered in this lecture of comparing basicity of triethyl amine and quinolidine was a question in JEE Mains 29 July Shift 2, 2022.
Guruji kaise itna achha parha lete ho aap🚴🤟🤟🤟🤟
Nece🔴
🔴nece
@@miriotogata9469 bhai ye nece kya h??🙏😀 Salute
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sir you are god of concept . hmare institute mei bhi bas ye bta diya tha ye nhi btaya tha kyu hota hai
Thank god legend return 😃😃😃
Sir please try to make a video on reducing agent like diborane and othe in organic chemistry.
Sir please make a video on how to draw structures of biomolecules
Finally after a long time....👍👍👍
Demo of lecture....is boom boom🔥oriented...beautiful art guruji💯🤗
Maaazaaa Aaya gurugiiii🔥🔥🔥🔥
Love u sir...best content sir
thank you sir😊
Eagerly waiting for a new video....ur lectures are amazing sir....thank you for providing excellent quality of education for free of cost....please don't stop uploading your videos
Sir Provide Us Help on Techniques of Purification Advanced Level Thanks Sir......
Maja aa Gaya sir subah subah charge kar Diya aapne tandav Karne ke liye...😊👍
Sir next video kb aayegi, topic kon sa h?
Thanks sir nice explanation all topic is covered in 22min❤
Sir boom boom concepts ki videos. ..daalte rha kro..bhut mja aata h...core concepts seekhne meim
Thank you for making a video on jee advanced topics
Sir please chemical bonding and periodic table videos in sequence
Sirji aap ki knowledge ko mera shat shat naman hain.
Sir please please please Ek video detail me Nucleophilicity order and leaving group order Par video banay
Thank you so much gurujii🙏
Hybridization sp2 kaise hua sir in transition state??
🙏🙏🙏🙏🙏🙏🙏Sir is video is hat kar ek question hai pls batana ms chauhan aur prevous yrs 41 years ke adv ke question paper bana kar pcm me kitne marks obtain kar sakta hu, I am self study obtain 98.67 %ile jan, repeater hu. Aur kaya iit me selection ho jaye ga ye sab se pls 🙏ap par faith hai.
Bilkul clear 🙏❤️
Sir ek doubt है.
Amine inversion se basicity kam q हो gayi?
Sp3 से sp2 to wo bonded pair jaate hai, lone pair to pure p orbital me chala jaata है, jisse aur energy बढ़ जानी chahiye और basicity बढ़ jaani चाहिए??
Plz anyone reply.......
Best video on amine flipping
Aap ka explanation accha hai
Thank you so much sir.
Sir provide us information of purification techniques advanced level
Sir please like this make videos on small topics that teachers usually don't go indepth 🙏
Sir thank you so much it was a much needed video for me I was struggling with this topic and I was not able to find any reliable explaination in this video thanks again sirrr..♥️♥️
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Sir pls make video about , Bayer strain theory & Dancing resonance
Keep Going..... 👍👍🙏🙏🤘🤘
sir fastest amine inversion ka order kese compare krenge??
Itna mast laga ki aisa lag raha hai maine phaltu ka coaching join kiya tha 11 mein coaching wale ne to 10% bhi nahi padhata tha apke comparison mein
great explanation- I recommend adding subtitles. People will greatly appreciate your work!
18:11 SP3 HOGA SP2 KI JAGAH , CORRECT SP3>SP2>SP3
Super se upar sir 🙏🙏🙏👌👌👌🌷🌷🌷🌷
Sir why Co+3 is oxidising agent plzz reply sir
Sir plz suggest any of ur video ...
Meko smaj nahi ata kha pure p - orbital draw kru kha hybrid Wala...
Plz explain plz😔
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Really very helpful thanks ❤
Thank uu sirrrrr😆😊😍😊😍😍😊😊🥮🍨🤟🍉🤟🍩🍑🤟🍉🍪😍🥰🥰🥰
Finally i found the Best chemistry teacher in this world
Just was eagerly waiting for ur video, always the one video from u sir, just making organic chemistry understandable, not memorable. Thnks a lot sir, sir plz aage kis topic pe aap video bnaa rhe h ye btaa diya kre last me.
SIR YOU ATE AWESOME PLEASE MAKE VIDEO ON MICHAEL ADDITION AND KNOVEGEAL REACTION
The umbrella inversion is what happens with me on a stormy day...😂😂😂😂
SIR , AMAZING 👏🙌🙌👌 explaination of Amines inversion that ever I seen on anywhere .........
Thanks Sir
Thank you very much, understood very well ✨
Really you are the best!!!
Thanks sir
Sir really ur teaching method is good
🔴nece
Sir reverse hypercojugation pdha do please
Kya baat hai sir👍👍👍
sir i am not able to understand ki in 2nd period size of s and p-orbital ka relation unversion of sp3 to sp2 se kaise hai.
I got it for phosphine kyuki vaha hybridisation consider nahi ho rahi hai but jaha consider kar rahe hai vaha kaise relate kar skte hai
bilkul samaz aa Gaya thanks sir
Best explained sir
Sir isn't the energy barrier big enough as resonance of benzene is also about 125 kJ / mol which we consider very very large which is nearly 5 times the energy barrier in amine inversion it should be considered big enough
thank you sir for this beautiful lecture
Thank you for this sir
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Very nice video .
Can you make a video on advanced level ionic equilibrium and titration.
You are THE BEST Teacher!😍
thank you sir for such a detailed video with nice examples also
Amazing sir you are great sir
Amazing 👌👌👌
Can you please explain the basicity order for imdazoline, imidazole and pyridine?
If flipping frequency is so high then how scientists identify the flipping..suppose if they do then how can they identify the transition state as sp 2
Sab pdhoge in yours coming universities curriculum.
@@IITianexplains okk sir..
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Unacademy per dekh lo..chal rha h.
@@tanmaysarkar8384 Is it unacademy neet or jee or app??
Mai bhi aise..Hi ruka rehta tha ki sir ki videos kab ayegi....Mai toh sochta sir ..Sirf plus padhate he......Jee mains se 15 din pehle pata chala .Ki free class bhi dete...Sala apne upar itna gussa aya ..Lol.
@@g1ntok147 plus pe free class hota h🙄
@@Fun_tainment06 Yes "special Classes" are free.
Also unacademy is the reason of low frequency of videos on youtube.
(They want us to watch on their platform).
sir pls try to provide pdf of what you teach.A HUMBLE REQUEST.!
Excellent explained.
One more great video by you .
Thanks for ur efforts ......
Sir iS on fire...Back to back vids 🔥🔥🔥
Amazing video
Sulphur aur phasporous amine inversion nhi krta h...q ke inki size bahut jyada hoti h isliye ispr lone pair stable hota h to ye Amin inversion nhi krta h
Sir organic chemistry booster pls
You are great
Sir ye batado quinolidine donate kaise krega kyuki bredt rule disobey hoga
Nhi hoga
Before and after sp3 hi h nitrogen
Sir, I love the rate at which you are uploading more and more videos🙏👍. Keep uploading more free content. love you.
Aapse jalne wale bhi bahut ho gaye hai sir. I am surprised that you got one like and one dislike but ignore it because ho Sakta hai jalne wale bhi Aapke video Ka wait Kar raha ho. Good morning sir 🙏🙏
Sir video on important reaction mechanism for jee advanced point of view..
Please sir because reaction mechanism to bahut sare hai but sabka mechanism itna important nahi hota.
To sir uspe he ek video jiski reaction ke saath mechanism bhe important ho (jee advance ke hisab se).... Please sir 🙏🙏🙏
Nice sir ji
please make a video on RE and SI face