Melanocytes vs Keratinocytes Made Easy: 5-Minute Pathology Pearls
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- เผยแพร่เมื่อ 10 ก.ย. 2024
- A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/pos... (dermpath) & kikoxp.com/pos... (bone/soft tissue sarcoma pathology).
Melanocytes and keratinocytes both can develop artifactual clear vacuoles around them. To dermpath beginners, this can make them difficult to tell apart. Once you know the trick, you can usually distinguish vacuolated melanocytes from vacuolated keratinocytes easily on H&E. And yes, I know this one is technically longer than 5 minutes. ;-)
Thanks to my former medical student, Sophia Ly, for typing up the transcript of this video so it could have accurate closed caption/subtitles! You can access a text version of her transcript of my video here: kikoxp.com/pos...
Other videos:
- Normal Skin Histology: • Normal Skin Histology ...
- Melanoma Basics: • Melanocytic Dermpath B...
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
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A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
I can't tell you how amazingly clear this video was. No one I asked could ever tell me why a melanocytes was a melanocyte.
I am so happy it helped you! Makes me glad to know these videos are benefiting others.
I would rather ditch my histology class and just watch your video. Thank you for making it fun to watch and learn
Dr Gardner, thank you so much for sharing your knowledge. People all around the world benefit from your help. Please have my gratitude
hi everyone ,if anyone else wants to discover keratosis pilaris home remedies try Elumpa KP Remedy Alchemist (Have a quick look on google cant remember the place now ) ? Ive heard some pretty good things about it and my buddy got cool results with it.
OMG... Ive got no idea how many hours I've spent on that topic .... when its so easy,... wish I was doing residency under your supervision... anyway HUDGE thanks.
Dear Dr. Gardner, thanks for your videos. I am an Italian DVM and Inter of the Veterinary Pathology Division of Utrecht University, I will start my residency in veterinary pathology in the near future. For me your videos are something great, they are clear, easy to understand and as this one, short, so a perfect combination. I wanted to say only thanks for what you do, is very useful and interesting!
Thank you!!
I can't thank you enough.
u r a role model.
how amazing are your videos.
Thank you, good differentials between melanocyte and keratinocyte
I like to talk about these cells as if they're people. Dr Gardner is a nerd, like most other pathologists are. I know because I'm a pathologist too. Thank you for another clear and helpful video. I'm a huge fan of your videos, your work and your mastery of the subject of Dermpath in general.
🙌
Crystal clear concept.
Thank you Dr Gardner for that amazing explanation.
Wow now I can say that I understood the melanocytes 🙌🙏 thank you!
Awesome! If you want to learn more about melanocytes, check out my nevus video (th-cam.com/video/jKZDqJez9jw/w-d-xo.html) and my melanoma video (th-cam.com/video/8N0IZZpF8ts/w-d-xo.html) too.
Awesome! If you want to learn more about melanocytes, check out my nevus video (th-cam.com/video/jKZDqJez9jw/w-d-xo.html) and my melanoma video (th-cam.com/video/8N0IZZpF8ts/w-d-xo.html) too.
BEAUTIFUL
Very helpful video. I had never heard these very important details to differentiate between the two. Amazing
Excellent teaching video. Humanizing the human cells is a helpful in making the distinctions “stick” for me. Poor keratinocytes, naked and alone. I’d love to see you examine some, woven into tough fibers, from a patient with Morgellon Disease. Also to hear what you think about the unique physiology.
Thanks for teaching us well.
What a great pearl. Thank you for doing this video.
I really like your videos. Thank you for making it available to all of us.
Superb teaching video! Love the quality and staining of slides as well. Thank you so much, Dr Gardner, for doing what you do and being an inspiration to many.
Thank you so much sir for your amazing videos ! Love from Jordan
Beautiful demonstration. Thank you sir
Another very clear discussion..thanks doc
Thanks jerad! This video helps me a lot!❤
Great video! I’d love to see a video about how/why these melanocytes respond to 532 or 755nm laser.
thank you sir for this amazing video🙏
Thank you for the great video. Waiting for more videos on dermpath
A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
Thanks 🙏🏻
Very well explained. Thank u so much🙏🏼🙏🏼
Thank you sir😊
Very helpful video. Thank you so much❤
Cant thank you enough
So beautifully described! Thank you.
Great explanation!!! Thanks dr buddy!
Fantastic
The explanation is brilliant!
Why is it that the vacuole forms outside of the melanocyte during processing? I'd expect it to shrink with the cytoplasm not emerge outside of it.
Thank you for the great video
Thank you!!!❤
Thank you sir... beautiful description....
Beautiful, thanks.
tq
Thank you
Sir pls upload video on vesiculobullous disorders of skin
Beautiful melanoma. Is it true that African Americans have extra-cellular melanin, whereas European Americans have intra-cellular melanin (as shown)? It would be interesting to see the differing histology of their skin side by side for comparison. Where does the “melanin cap” reside in people of African descent ? Is that why they don’t get melanoma except in their nails and soles of feet ? Please clarify why they are immune to the sun’s ultraviolet effects.
Sir u are rocking 😀
❤❤❤❤❤
VVVV nice video
👏👏👏
nice video explanation, can u explain koilocytotic change if possible?
Will try to cover that at some point. I think I touch on it in this video if I recall. th-cam.com/video/G31xlSgYSlw/w-d-xo.html
thank you for simplifying this! are there any videos where you show eos/neutrophils?
Maybe I should make an eosinophils vs neutrophils video. Good idea! Thanks!
Well, good video. But how vitiligo works then. Do you know?
It’s a type of autoimmune disease where lymphocytes (white blood cells) attack the melanocytes and destroy them. This leads to loss of skin pigment in the affected areas.
wow
You are so goood!
Who discovered keratinocytes or who named keratinocytes
Dr Jerad please show us langerhhans cells
I discuss Langerhans cells in th-cam.com/video/yQQ2Dmz42Vs/w-d-xo.html
Dr Gardner can you speak More slowly? Please and thenks
I have been trying to speak more slowly my whole life but unfortunately I’ve been unsuccessful so far! Even most native English speakers say that I speak too rapidly. I’m sorry! Some of my videos have English subtitles. Also you can adjust playback speed to slow the video down. Click settings button in bottom right of video for these options. Best wishes.
@@JMGardnerMD thank you for. All Dr Garder