Great sir...I feel myself much privileged to attend such a wonderful lecture,are truly working for benefits of our future. I would truely like to give a vote of love and gratitude to the eminent personality , giving us such an informative knowledge. Thanku sir ji May Almighty ALLAH bless you 💯💯
In case of positive regulation of trp operon when region 2 and region 3 form weak hairpin structure and ribosome is stopped before that region where as rna polymerase will continue trancribing the structural genes EDCBA and translated to form proteins for biosynthesis of trp.. Sir, can you please expln me if ribosome is stoped befr 2-3 region then how after transciption by rna polymerase translation is taking place ( ribosome is stopped within leader sequence)
@@muskanparveen1267 Shine dalgarno was already their in the upstream that i know that was not my point, but i have issue with the region where hairpin is formed between 2 and 3 region and ribosome is stopped from moving further due to this structure although transcription had already processed so no issues with that...but since ribosome is stoped at that location then how translation of rest part is taking place
The answer is correct but explain is not... I guess SD is deleted then no transcrption will be controlled by it but each Trp gene has a SD seq. So ribosome will directly bind to trpE gene SD seq and increases the expression rate in low conc I guess. If wrong plz correct me
Answer 2 ia correct because leader sequence show attenuation so expression rate get decrease but if mutation occurs in SD of leader sequence then it's expression rate i e transcription increases ... But as tryptophan is repressor it's high concentration represes the expression so concentration of tryptophan should be low so expression should be increases.. 2 is correct
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Sir your teaching is perfect for better understanding. Thank you so much sir.
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Marvelous, outstanding lecture thank you so much sir 💖❤
Great sir...I feel myself much privileged to attend such a wonderful lecture,are truly working for benefits of our future. I would truely like to give a vote of love and gratitude to the eminent personality , giving us such an informative knowledge. Thanku sir ji May Almighty ALLAH bless you 💯💯
Best teacher , best explanation ever
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Excellent explanation sir. very helpful lecture and all doubts are clear. Thanks
Thanks sir for this easy explanation
Wonderful,,awesome sir
Best lecture
Nicely explained sir
thanks sir , its very helpful sir
Sir, how stop codon (between 1&2) will be bypassed because that will terminate translation?
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Why not the option 1 for question no. 9 in the high level of tryptophan transcription will increase if sd sequence of leader sequence is inactivated
If the UGG is replaced by GGG sequence of glycine in case of mutation than what happens....
Thanx sir
Good morning sir
Plz explain me ...after hairpin loop between 2 and 3 , from where then ribosome bind to other part of mrna and also structural genes
I too hv same doubt...if you get any ans plz do mention here
@@sushmitapaul9944 go for animation video....u will get the answer
If you know the reasn u can tell me instead of such a long process fr just a point answer
If you hv prblm explng Then gv me the link
@@sushmitapaul9944 did you find the answer? I am looking for the same.
Hello sir... Thnks ur lectures r very helpful I have a request I could not find the video on genetic codons n amino acids...
Sir please upload transcriptional regulation in eukaryotes.
Good morning sir 🙏
Sir agar ribosome region 1 pr he stop ho gya to gene trpE D C B A ka translation kese hoga
thanks sir.....
In case of positive regulation of trp operon when region 2 and region 3 form weak hairpin structure and ribosome is stopped before that region where as rna polymerase will continue trancribing the structural genes EDCBA and translated to form proteins for biosynthesis of trp..
Sir, can you please expln me if ribosome is stoped befr 2-3 region then how after transciption by rna polymerase translation is taking place ( ribosome is stopped within leader sequence)
@@muskanparveen1267 Shine dalgarno was already their in the upstream that i know that was not my point, but i have issue with the region where hairpin is formed between 2 and 3 region and ribosome is stopped from moving further due to this structure although transcription had already processed so no issues with that...but since ribosome is stoped at that location then how translation of rest part is taking place
@@muskanparveen1267 its not about replication dear the problem is with translation.
Anyways thank you so much
Any kind of Helicase is involved in replication dear not in tranlation
@@muskanparveen1267trp operon is not found in eukaryotes bt anyways thanks 👍
Is anything wrong with question 9?
Yes, I feel so too, Sir was saying decrease while the option said increase. Even I am confused.
Yes exactly... According to the explanation also the answer must be option 4
The answer is correct but explain is not... I guess
SD is deleted then no transcrption will be controlled by it but each Trp gene has a SD seq. So ribosome will directly bind to trpE gene SD seq and increases the expression rate in low conc
I guess. If wrong plz correct me
I think 4 would be correct answer
Answer 2 ia correct because leader sequence show attenuation so expression rate get decrease but if mutation occurs in SD of leader sequence then it's expression rate i e transcription increases ... But as tryptophan is repressor it's high concentration represes the expression so concentration of tryptophan should be low so expression should be increases.. 2 is correct
Thank
you sir
Thank you so much sir