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You need a strong EWG for the nucleophilic aromatic substitution to work. Even if you manage to make p-chlorophenol after the first round of substitution (harsh conditions, benzyne intermediate, fun stuff 😆), it would get immediately deprotonated and you'll never be able to substitute the second chlorine on an extremely electron-rich phenolate anion. Also, why would I even bother making a video about this synthesis if it was that easy? 😜
@@7hunderstorm242 I hear you, lol. Questions like this are common trick questions on the test which seems like they should be easy, but in reality they are not. That's why I've made this (and a ton of other synthesis videos on my channel).
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I'm shocked with the quality of your videos ! Please continue !
Haha, thank you! I have no plans on slowing down!
Why can't you just chlorinate twice to make p-dichlorobenzene and then Sn with NaOH ?
You need a strong EWG for the nucleophilic aromatic substitution to work. Even if you manage to make p-chlorophenol after the first round of substitution (harsh conditions, benzyne intermediate, fun stuff 😆), it would get immediately deprotonated and you'll never be able to substitute the second chlorine on an extremely electron-rich phenolate anion. Also, why would I even bother making a video about this synthesis if it was that easy? 😜
@@VictortheOrganicChemistryTutor I was just Hoping lol, thanks for the response !
@@7hunderstorm242 I hear you, lol. Questions like this are common trick questions on the test which seems like they should be easy, but in reality they are not. That's why I've made this (and a ton of other synthesis videos on my channel).
Sir continuity