Gestational diabetes mellitus

Pathophysiology: Human placental lactogen secretion
Screening:
24-28 weeks gestation
1-hr 50-g GCT
3-hr 100-g GTT
Treatment / management:
1st line: diet
2nd line: insulin, glyburide, metformin
Target blood glucose goals:
Fasting: ≤95 mg/dL
1-hr postprandial: ≤140 mg/dL
2-hr postprandial: ≤120 mg/dL
Postpartum management:
Fasting glucose at 24-72 hr
2-hr 75-g GTT at 6- to 12-week visit