A brief history of protein structure prediction and design

In this talk, Mohammed AlQuraishi provides an overview of the history and recent advancements in protein structure prediction and design. Topics include:
The evolution from physics-based methods to data-driven approaches.
Key milestones like AlphaFold's impact on structure prediction.
How generative AI, including RF Diffusion, is being used to design proteins with specific properties.
This presentation highlights the progress in computational methods and their role in addressing long-standing challenges in protein science. It is perfect for anyone interested in the intersection of AI and structural biology.
Thumbnail credit: Ian Haydon (Institute for Protein Design)