Cliff Brangwynne (Princeton & HHMI) 1: Liquid Phase Separation in Living Cells

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  • เผยแพร่เมื่อ 5 ม.ค. 2025

ความคิดเห็น • 30

  • @mazin627
    @mazin627 4 ปีที่แล้ว +9

    This was great. I came across a term called liquid liquid phase separation in a paper, didn't understand but thanks to this video I now have some insight. Thank you.

  • @soudaminisahoo8935
    @soudaminisahoo8935 ปีที่แล้ว

    This is indeed helpful to understand LLPS (liquid-liquid phase separation) from a physics point of view.

  • @rickfearn3663
    @rickfearn3663 5 ปีที่แล้ว +3

    Cross pollination between physics and biochemistry is so very exciting!!! Thanks for opening our eyes to these exciting developments. Question is what will the future bring? Thanks Dr. Brangwynne.

  • @ankitbioinfo
    @ankitbioinfo 5 ปีที่แล้ว

    Very nice talk. Finally I landed here after hearing the talk of Tony hyman, Frank Julicher and Eric Dufresne.

  • @katenicholls5301
    @katenicholls5301 3 ปีที่แล้ว

    Thank you SO much for your clarity and for the generosity of your time. I am fascinated.

  • @benjaminjoshua6235
    @benjaminjoshua6235 8 หลายเดือนก่อน

    Very great lecture. Looking forward to more videos.

  • @王祥-k5l
    @王祥-k5l 6 ปีที่แล้ว +3

    membraneless organelle will change many the molecule biology concepts, thanks Cliff Brangwynne

  • @paul3116
    @paul3116 5 ปีที่แล้ว +8

    Fantastic talk!
    Just a small detail I'd like to add: I wouldn't define the Golgi apparatus as 'a funny name', it comes from Camillo Golgi, an italian scientist who discovered this organelle.

    • @jamesdriscoll9405
      @jamesdriscoll9405 5 ปีที่แล้ว +1

      You have to admit, it's a little funny that he's known for his little apparatus. Seriously, mad props to the pioneers of cellular biology!
      And whatever it takes to memorize all of this crazy crazy stuff!

  • @ansonoconnor2035
    @ansonoconnor2035 3 ปีที่แล้ว

    This video was fantastic. Great explanations and great lecturing.

  • @anonviewerciv
    @anonviewerciv 4 ปีที่แล้ว +1

    Macromolecules as liquids. (15:30)
    7:17 21:51 Organelles without (phospholipid) borders.

  • @mehdisharifitabar7745
    @mehdisharifitabar7745 5 ปีที่แล้ว +2

    Hi Cliff, fantastic talk! . thank you

  • @shrishtiwari7750
    @shrishtiwari7750 3 ปีที่แล้ว

    Excellent Lecture. Thanks for clearing the basic concept.

  • @davidgurarie6712
    @davidgurarie6712 6 ปีที่แล้ว +2

    These are novel and important idea. Thanks for nice intro.

  • @thefalcon217
    @thefalcon217 8 หลายเดือนก่อน

    What effect does milli meter microwave raditation have on liquid phase seperation, given it can increase hydroxy radicals in water?

  • @samingzadeh4494
    @samingzadeh4494 4 ปีที่แล้ว

    Loved it. Thank u Prof. Brangwynne!

  • @captainquinine
    @captainquinine 2 ปีที่แล้ว

    this talk was super good

  • @xXRandomPianoXx
    @xXRandomPianoXx 4 ปีที่แล้ว

    28:38
    You said that with a low interaction parameter (high temperature) the system remains in a high entropy/mixed state. And as you raise the interaction parameter, the system will favor phase separation. But the sign on the y-axis is indicating the opposite. In other words, based on the graph, it appears that a low interaction parameter drives the system into phase separation, and so on... Could it be that the interaction parameter is relative? (ie. low interaction between heterogenous molecules (phase separation) vs. low interaction between homogenous molecules (mixed state))?

  • @RanjitDe
    @RanjitDe 5 ปีที่แล้ว +1

    Very helpful for a beginner like me. Thanks.

  • @moofaca
    @moofaca 3 ปีที่แล้ว

    Thanks for the great talk!

  • @davidkincade7161
    @davidkincade7161 4 ปีที่แล้ว

    Great stuff!!

  • @sukuraluoriver9813
    @sukuraluoriver9813 4 ปีที่แล้ว

    thanks

  • @jamesdriscoll9405
    @jamesdriscoll9405 5 ปีที่แล้ว +6

    Everbody gangsta until the phase change

  • @weiwang7446
    @weiwang7446 4 ปีที่แล้ว

    wish I could give 1000 thumb up

  • @Echodonut
    @Echodonut 5 ปีที่แล้ว +1

    Coo

  • @hollya.g.86
    @hollya.g.86 3 ปีที่แล้ว

    You're a soft squishy robot, not me

  • @jatigre1
    @jatigre1 5 ปีที่แล้ว +1

    I wonder when biology is finally going to admit and understand that without a "spirit" / "IS-BE" there is no life animating-organizing force behind life-forms

    • @davidkincade7161
      @davidkincade7161 4 ปีที่แล้ว

      See “intended evolution”- there is a “life force” as the substrate to physics and chemistry.

    • @patldennis
      @patldennis 4 ปีที่แล้ว

      Huh?