Reconstitution Calculations - How to Solve 5 Important Examples | RxCalculations

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  • เผยแพร่เมื่อ 27 ต.ค. 2024

ความคิดเห็น • 36

  • @PharmaceuticalCalculationsEasy
    @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว +5

    Greetings Everyone. Thank you for watching. A gentle reminder for you to take the free reconstitution calculations quiz: www.rxcalculations.com/reconstitution-calculations-quizzes/ to improve your understanding.

  • @yushausaleh6991
    @yushausaleh6991 7 หลายเดือนก่อน +1

    Thank you for your tireless work

  • @__mek_
    @__mek_ 4 ปีที่แล้ว +3

    )We have an ampicillin product for
    reconstitution. It contains 2.5 g of ampicillin to
    be made up to 100 mL. To what volume should
    it be made to give 100 mg per 5 mL dose?

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว +2

      Thank you Maria for watching and for the comment. Here is the solution to your question: jo.my/rlqpdq

    • @__mek_
      @__mek_ 4 ปีที่แล้ว

      @@PharmaceuticalCalculationsEasy thank you very much. Very helpful indeed.

  • @MindDietTV
    @MindDietTV 3 ปีที่แล้ว +1

    Thank you so much for creating these videos . Please could you kindly link reconstitution solutions(if available ) where the powder volume does not contribute to the final volume .

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  3 ปีที่แล้ว

      Thank you for the comment. In situations when the powder volume does not contribute to the final volume, then the final volume will be the same as the volume of diluent added and all pertinent calculations will be based on the volume of the diluent. Hope this helps.

    • @MindDietTV
      @MindDietTV 3 ปีที่แล้ว

      @@PharmaceuticalCalculationsEasy Got it , I am going to work out some practice questions in this concept . Thanks once again .

  • @agusta6587
    @agusta6587 4 ปีที่แล้ว +1

    Hello Dr. Danquah. Great Job! Can you help with this problem? A female patient weighs 79 kg, and Amoxicillin 4 mg/Kg IV administered over 30 mins is ordered once every 24 hrs for 10 days. Amoxicillin powder for injection is available in 250 mg vials. The 250 mg vial is diluted with 5 ml 0.9% NaCl. If the patient's dose is diluted in 50 ml of 0.9% NaCl, what is the administration rate in ml/hr? Thanks, v m.

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      Thank you Kernel for watching and for the question. Here is the solution: jo.my/flowratecalculations. The accompanying video will be published soon. Appreciate you being an active member in the pharmaceutical calculations community.

    • @agusta6587
      @agusta6587 4 ปีที่แล้ว

      @@PharmaceuticalCalculationsEasy Thank you very much, Sir!

  • @yushausaleh6991
    @yushausaleh6991 7 หลายเดือนก่อน +1

    I should have pay my tuitions fee to you instead. Thank you so much

  • @henrysourial3328
    @henrysourial3328 4 ปีที่แล้ว +1

    Hi can you help with this question? (board exam on tuesday)
    The label of a dry powder for oral suspension states that when 111 mL of water are added to the
    powder, 150 mL of a suspension containing 250mg/5mL ampicillin are prepared. How many ml of
    water should be used to prepare a suspension which would contain a dose of 8 mg/kg per 5 mL. to be
    given to a child weighing 60 lbs using same total amount of drug as of 150 ml of 250mg/5ml
    suspension.
    I have an answer but id like to know if i did it right

    • @henrysourial3328
      @henrysourial3328 4 ปีที่แล้ว +1

      I got 39ml PV and 132.8ml of water, let me know, thanks

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      Thank you Henry for watching and for the comment. Your answer is correct. Here is the solution: jo.my/g5mao4 . The accompanying video will be published soon. Keep up the good work and happy studying.

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      Thank you Henry for watching and for the comment. Your answer is correct. Here is the solution: jo.my/g5mao4 . The accompanying video will be published soon. Keep up the good work and happy studying.

    • @henrysourial3328
      @henrysourial3328 4 ปีที่แล้ว +1

      @@PharmaceuticalCalculationsEasy do you have time for one more question ?
      You've 20 ml ampoule of a conc. 0.75 %, if you need to prepare 250 ml solution have conc. of
      0.125 % so what is the volume of diluent needed to dilute soln.?
      I tried the fv=dv+pv method but my answer is completely different from what is on my document.
      can you help me with this one ?

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      @@henrysourial3328 The question is potentially ambiguous. Is it ampoule or ampoules. Nonetheless, confirm whether the answer is 208.33 mL..

  • @cometoChrist
    @cometoChrist 4 ปีที่แล้ว

    Thank you so much Dr! May I ask this question regarding reconstitution of oral preparations: 'The label of a dry powder for constitution into pediatric drops states that when 12 mL o
    f purifed water is added to the powder, 15 mL of a pediatric suspension containing 50 mg of amoxicillin per milliliter results. How many milliliters of water should be added to prepare the dose of amoxicillin in each 10 drops if the dropper delivers 20 drops/mL, the child has a body surface area (BSA) of 0.4 m2, and the dose of the drug is based on 50 mg/m2 of BSA?'
    Medase paa

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว +1

      Thank you Jenn for the questions and for being an active part of the community. Here is the solution to the question th-cam.com/video/bkwC52dP7bw/w-d-xo.html . Happy studying.

  • @oludayohaastrup6972
    @oludayohaastrup6972 2 ปีที่แล้ว +1

    a nurse is preparing to administer cefazolin 250mg via intermittent IV bolus every 8 hours. Available is a 500mg vial. The packet insert instructs to add 2 ml to yield 225mg/ml and then add 50 ml of 0.9% sodium chloride. How much cefazolin should the nurse add to the 50 ml of 0.9 sodium chloride?

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  2 ปีที่แล้ว +1

      Thank you for watching and for the comment. Below is the solution.
      (225mg/1 mL) = (250mg/X mL)
      X = ((1 mL x 250 mg)/225 mg) = 1.11 mL

    • @oludayohaastrup6972
      @oludayohaastrup6972 2 ปีที่แล้ว

      Thank you. Got the same answer too

  • @henrysourial3328
    @henrysourial3328 4 ปีที่แล้ว +1

    do you have time for one more question ?
    You've 20 ml ampoule of a conc. 0.75 %, if you need to prepare 250 ml solution have conc. of0.125 % so what is the volume of diluent needed to dilute soln.?
    I tried the fv=dv+pv method but my answer is completely different from what is on my document.
    can you help me with this one ?

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      The question is potentially ambiguous. Is it ampoule or ampoules. Nonetheless, confirm whether the answer is 208.33 mL..

    • @henrysourial3328
      @henrysourial3328 4 ปีที่แล้ว +1

      @@PharmaceuticalCalculationsEasy yes the answer is 208.33 - can you please provide and step by step explanation ? and why does the amp or ampoule(s) matter?
      I appreciate your time and effort to answer my questions

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      @@henrysourial3328 Here are the step-by-step solutions: jo.my/ourpwf (algebraic method) and jo.my/xwbrrm (alligation method). Regarding the ampoule(s), the amount of api needed to make the 250 mL will require more than one ampoule. Hope this helps.

    • @henrysourial3328
      @henrysourial3328 4 ปีที่แล้ว +1

      @@PharmaceuticalCalculationsEasy thank you so much. makes sense , appreciate the effort

  • @agusta6587
    @agusta6587 4 ปีที่แล้ว +1

    a bottle of PCN powder contains 20,000 units of penicillin.when reconstituted with 25.3 ml sterile water for injection, it produces 500,000 units/ml. How many milliliters of sterile water for injection should be added to the bottle to provide 1,000,000 units per ml? Thanks.

    • @agusta6587
      @agusta6587 4 ปีที่แล้ว +1

      Typo: Initial vial had 20,000,000 units

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      You may see the solution to the question here: jo.my/cewhth. Thank you Kernel for watching and for being an active part of the pharmaceutical calculations community.

    • @PharmaceuticalCalculationsEasy
      @PharmaceuticalCalculationsEasy  4 ปีที่แล้ว

      You may see the solution to the question here: jo.my/cewhth. Thank you Kernel for watching and for being an active part of the pharmaceutical calculations community.

  • @svalson
    @svalson 4 ปีที่แล้ว +1

    You are god send. Thank you.