Answer to prayer. I recently had routine blood work completed. B12 Results @ 1,383, and i was concerned it is too high. From what i gathered from your post is that my body is in an optimal state of repair. It now makes sense for the less inflammation, more energy ( I can go more than 3 hours cleaning) etc. Thank you kindly. 🎉🙌
@@windy42305It’s very common to have high serum B12 when you have a B1 deficiency. If he’s deficient in B1 he can have sufficient and also high serum B12 without utilizing it, a so called functional B12 deficiency. I would definitely add some more B1 supplements like Benfothiamine 3-400mg to my routine if I were him. The B-complex is not enough if he’s deficient in B1.
When I was 65 my primary car physician during an annual health visit did a quick sensation check on the bottom of my feet. I could not feel it. My B12 blood test was normal although on the low end of normal. She recommended take a B12 supplement with 2000 mg. I did and within 6 days my feet had returned to pretty normal sensation. They continued to improve for more than six months. I continued taking B12 and will for the rest of my life.
I have ideopathic peripheral neuropathy and also had normal b12 levels but low normal. I’ve been taking 2000 mcg of b12 daily for 3 weeks now and my symptoms have diminished significantly. I found this through my own research. My neurologist never mentioned it.
@@SD-co9xe I'm glad to hear that. My chiropractor told me to take vitamin B. I bought a B complex that had only 100 mcg of B12. After further research, I realized I could probably use more. Do you take 2000 mcg all at once or split it up during the day, taking 1000 mcg of B12 at different times of the day?
@@free_soul9154better yet get a mTHFR test/homocysteine levels. Everyone is different Methylated B's has negative sides for me. Un methylated b complex is great for an over methylator because of the gradual conversion.
At the age of 35, one day at a very stressful job, I suddenly lost the feeling in the tips of my toes, fingers and the ability to taste also having lost the feeling in my tongue. I also developed a splitting headache, lost a lot of weight and noticed my hair falling out. My doctor instinctively tested for my B12 levels. My levels were so low, that they did not register on the test. She put me on weekly injections and was concerned if I might have developed permanent nerve damage. She said also that because I had premature grey hair, that it was very luckily that I did not absorb B12 well. Luckily, after 6 scary months, I gradually regained all the feeling back with no damage. More than 10 years have passed, and I make sure I take B12 almost daily now.
I started with 1000mcg Methylcobalamin, it was ok, a nice boost to me day. But recently I found some 5,000mcg that dissolve under your tongue. I take them after breakfast and boom I am energized. I am recovering my an illness that prevented me from my daily three mile walk for 5 months, now I am quickly working my way back.
Thank you once again Dr Omole on TH-cam for this information. Since following you (for some years now), my kidney stage results has decrease from stage 3 to stage 1. You saved me from dialysis. Thank you and please keep the videos coming!! God Bless...
I had to take 35,000 mcg of B12 everyday years ago for 6 months, I then started to reduce it and over a year I had to stabilize at 15 to 20,000 a day for almost a year I’m now at 10,000 a day . I’ve had 5 low back surgeries and 3 neck surgeries. I was also exposed to benzene severely in 88 . And my adrenal glands are enlarged to about the size of a half dollar. It was to the point I didn’t want to get out of bed or take a bath . My family didn’t understand they thought I was just lazy and in self pity. I was praying and praying for help but drs didn’t help . I was woken up one night around 3am to go and research adrenal fatigue. And the video said to take but loads of B12 so I started with 2,000 and each morning I doubled it until I was back up and moving around. It took about two weeks. I was back my garage doing things . I hurt because of my past injuries I’m not on any pain meds and I don’t let the pain stop me as much as it used too . I recover and hit it again, I recover and repeat. I was 27 when exposed to benzene, I’m here because of my prayers and Gods blessing, I was 21 when I broke my back and I was 43 when I injured my neck that was the one the took me out of work. I’m now weeks away from 64 . I still do things but much much slower. But I’m persistent until it’s done . I weld build things do woodwork and I a retired electrician. Each day is a gift even in the pain and believe me it’s painful. Some days I can’t walk , god ask us to praise him even in the valley as well as the mountain top and I can tell you without him I couldn’t make it in those valleys. You would be amazed what he will do for you in just praising him on those difficult days , God is Good ❤ 1-1-25 to add drs are now attempting to send me to Methodist hospital in Houston for test , they finally looking into the masses on my R/ kidney and adrenal gland mass . After the damage is done . The pain through out my body is horrible. If it hadn’t been for god I doubt if I would have made this far. God lead me to B12 and he will continue to lead me until my last breath. The tumors has caused my heart to enlarge inwardly over time , drs refused to acknowledge the problems from the adrenal gland and they didn’t address those issues.
I have problems having energy to do things and thinking faster. Sometimes I think I have depression and mood swings. And B12 has helped me feel normal, energized, positive.
@H-jb4tf thank you for the advice. I try to eat more vegetables now, becus I hardly did growing up…I do noticed when I eat too much carbs I feel so tired.
Thank you I was taking about 10,000mcg per tab I two little tablets because I needed the energy without taking caffeine. I was worried I would might be taking too much. Thank you again.
Thank you for this information and explaining the risks and benefits. My doctor doesn't think B12 levels are not a big deal so I am in this on my own. YT vids are helpful but reading the research lit answers many of the questions you have answered. Again, thank you.
Many physicians are not dialed into supplements as essential to older people. They like medicine to treat your high illness, like blood pressure, high cholesterol, etc.
If you’ve ever had Trigeminal Neuralgia, an excruciating facial nerve condition that’s nicknamed “The Suicide Disease,” you wouldn’t think anything is too much when it comes to B12. Because of sublingual Methylcobalamin taken at 5,000 mcg dosage, my TN completely disappeared! It was nothing short of miraculous-keeping me from having to have a scheduled MVD surgery (brain surgery) at UCI in Irvine, Ca. Three years later, I am still symptom free! I still take sublingual 5,000 mcg every two days just to make sure the TN doesn’t come back. Back in the 50’s sublingual B12 was widely used for TN and MS as a first line of treatment. But then Big Pharma arose and… well you know the rest of that story. It’s an all-too familiar one. 😮
Interesting to read your comment. I have intermittent TN and have monthly injections due to low absorption issues. I wonder if I should get my dose increased.
I cannot even understand how b12 can heal cluster/similar. I use the highest one CAN use without making a issue for the rest of the body . Because , its not like one doesnt have a limit ? I use triptan and o2 (8 to twelve bar/high pressure) against cluster /suicidal headache. I couldnt make it without,tbh. No matter supplements. It IS a infection on the back of the eye , right ,so one needs triptans/ergotamine,to contract bloodwessel that is swollen ...i think? Its the only thing that work for me. Even strong petidin/ketamin/morphin wont help. I have tryed everything ,im sure. All neuralgica medication,supplements,botox ,nerve blokade's (waist of time). I have been offered surgery,but the high risc surgery dont often work,so... I thought everyone with this type of headache get high pressure high bar o2 ? And nausia medication ,of course. This type of headache is easy to spot,it makes one eye deep,bright red and swollen,and tears will flow ,constantly (and nose will run,at the same side). The patient cannot lie still , like people with migraine will do. Its a horrible state . But it MIGHT disapear, or at least become a rare thing . So, cross fingers !
One can get nerve damage, higher risc of blood clogs and lung cancer , anemia , and so on, with to much b12. I DO fet you want to take your chance,if your life is filled with those seizuers ,tho. They can destroy lifes,and they do. I know. But i still wonder , dont you have ANY help from 02(it HAS to be with pressure mask,and at least 8 bar for 15 minutes, or it wont work. Normal is 2 bar ,or so...,it IS a lot. But it has to be. I use 10 bar, so i empty a bottle very fast. Has to have those big ones! ). You dont use ANY other help for your seizuers?
Awww yes, big pharma!! That's wonderful that they gave you 5, 000mcg of B12. When they treat cyanide poisoning or malaria they give people 10,000 times the amount of B12 every day until they're better. 10,000 times. Congratulation on finding the help you needed.
Thanks so much Doc.God bless you for the informative videos . l fee better any time l take B12 supplements but l still feel numbness in my feet and hands .
Take all Vitamin B, they all can do a lot:) And Benfo plus Allithiamin listen to Elliot Overtone on TH-cam. Magnesiumglycinate and some adaptogens like rhodiola rosea, passion flower ( I love passion flower extract:). Greetings from Germany
I have high homocysteine due to homozygous MTHFR mutation. High doses of methylcobalamin were prescribed, but a few months later I had odd symptoms, including strange aches and muscle pains, brain fog and terrible insomnia. Soon after, I broke out in a bright red, full-body rash that lasted several days. The high-dose B12 was the only recent change I had made, and it turns out I am allergic to cobalt. This also explained a decades-long reaction I had had to certain types of eye makeup, which caused oozing, painful rashes. I always thought some unknown red pigment was to blame, but it was blue from cobalt. Skin rashes are one thing, but the full-body and brain problems I had with high doses of methylated B-12 were debilitating. So it's not correct to say it is completely safe at high doses. A small percentage of us will have an allergic reaction
@@Lauren-vd4qe no, I haven't worn eye makeup in many years. When it used to happen with certain colors, years ago, the reaction was almost immediate. The recent illness and rash occurred after starting a high dose of B12 and it resolved a couple weeks after stopping it. If you don't believe it's possible to have such a reaction to B12 or an allergy to cobalt, look it up rather than diagnosing a stranger from afar
B12 became extremely high after taking a strong dose for a short time. During seizures, I experienced a fast heart rate, palpitations, nausea, vomiting, profuse sweating and almost went into cardiac arrest a couple of times. My liver and kidney numbers were also extremely high.
@@Me-555 Yikes! My reaction was weird and very unpleasant, but nothing like that. Doctors need to realize B12 supplements can harm some people and more is not always better.
Thanks for clarifying the issues with B12 minimum and ODA it was very helpful! I did not know the relationship with nerves and B12 with which I have a problem, and know now to increase the dosage!
One thing important to remember if you want to check your b12 level for a deficiency, do not start supplementing before bloodwork as it will skew your b12 serum levels.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
This is an awesome video. And I am SO GLAD I stumbled across it. I was researching a prep used for vertigo, and got more info that I needed because my husband has recently dianosed dementia, at 83. The meds for dementia have horrible side effects, and I took him off them pronto. I am convinced now, that the tiny dose of B12, that the NP recommended was a moot point, especially because she failed him at every turn, saying that his 104 weight, down from 140 was nothing to worry about. It turned out to be colon cancer. I got another opinion. Now, his memory is so short, and he gets lost if he has to make more than one turn, so now, I do EVERYTHING. l fully intend to put him on a high dose of B12, and a prep, I looked into for my vertigo has a high dose. I have him on MCT oil, and Benfotiamine3, and D3, 4,ooo, plus k2. Other than the memory and directional issues, he does very well. Gets wholesome food, and good sleep, and, even though he still complains of our long walks when we were dating, I see that he does get enough walking LOL Thank you SO much, Dr., I will subscribe!
GREAT!! You just answered my questions! I have internal vibration (getting worst everyday) and it could be due to nerve damage. I hear that vit B12 would help me get rid of those vibrations but I was not sure about the dose to take. Now I can take the 5000 mcg pills I bought without any worries. Thanks sooo much! Dominique
@@Lauren-vd4qe I started 8 days ago and I already see a big difference...I almost have no vibration during the day and at night it's like 30% of what it was at the worst. I keep taking them for 4 months because there is a warning on the bottle saying to check with my doctor after 4 months. :-)
Make sure to have enough B1( benfotiamine, allithiamine) and B6 (P5P only) and methylfolate with it and very important with enough electrolytes (especially potassium)
Love this video. I started taking B 12 5,000 mcg liquid, 2 droppers full three times daily and it improved my mental focus by the end of the day. I believe we cannot get enough nutrients in our food, and we also need enough stomach acid to absorb the nutrients. Over the age of 30, our stomach acid declines. I am taking high doses of B vitamins now and can feel a big difference in energy levels. A friend of mine has horrible nerve pain and she has refused to megadose B vitamins. With this Medical Doctor video, hopefully she will now believe me.
Thanks for making this video, I was about to purchase Nuphoria Gold for neuropathy and saw it had 125,000% RDA of Vit B12 and was concerned, this video cleared that up.
Most people don't have a problem with knowing how much to take. Their problem is that they use the doctor's Serum B12 test results to tell them if they are okay. They do this without knowing the Methionine Cycle the Folate Cycle and the MS enzyme that connects them. If more doctors performed MMA and Hyc tests rater than an almost useless Serum B12 test, they would have a much better idea of their Methylation and Transsulphuration status, which is what it's all about.
Thank you tons and bunches doc for being informative and caring. I'm pushing the subscribe button now. Quality of life is my goal as a senior citizen, and so much information is vague at best. Thank you for the heads-up
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
I’m going to post you constantly to my group because it’s too much work for me I’m constantly repairing my self it’s a long fight. Plus I was diagnosed then repaired..li have so many stories about my road.,
Thank you very much for getting this message out there. Is extremely difficult for patients to combat this silly misconception that doctors have about B12 overdosing. I have severe neuropathy in my feet and legs so I've been injecting two ml a day instead of one. But I would like to even do more. My feet hurt so bad. I'm going to watch your other video as well that you mentioned at the end of this video to see if I can fix my feet. Keep debunking these misconceptions of B12. Something needs to change so we can buy B12 ampoules OTC in the US and UK.
Could you maybe talk about subacute combined degeneration caused by B12 deficiency/PA and what can be done to fix the nerve damage? That would be a great video. Thanks so much
@@nageshnimbalkar4091 Well, it's a little hard to say. But I like to think it is, even if it's just a little bit. It seems when I'm in a flare-up, if I inject B12 directly into my thigh instead of my belly where it has to kind of get through some fat, I think if I inject it directly into my leg it's got a better chance of reaching areas of the lower extremities. And I'd like to think that it does relieve my feet from excruciating pain but doesn't eliminate it all together and it just comes right back If I skip a day. Without it, it would get worse So if nothing else it's keeping it from being like it was last year where I was crawling on the ground because I couldn't walk. It is excruciating and it's one of my worst issues from pernicious anemia. I wish I knew how to help it because it's debilitating in its running my life. B12 is all I have and I'm all I have, because doctors know nothing about this. They go home at the end of the day and don't have to worry about it but I have to live with it every second of the day and it's extremely excruciating It's a terrible disease and doctors don't know anything about it. I feel like I have nowhere to turn but myself. Thank goodness for B12 because it's all I have and at least I'm still alive, but I'm not living that's for sure, because of neuropathy. I wish I had a better answer for you. But all I can say is without B12 I would be in a wheelchair. So whatever I'm doing it's at least keeping me from that.
B12 is doubtless relatively safe in big doses, however in large doses if you are otherwise already healthy it can give you difficulties focusing your attention due to excess energy. I am not sure about B12 to treat peripheral neuropathy (if it is caused by excesses of minerals or excess Vitamin B6, ALA is a better treatment to remove the excess from your system which will lead to healing). Excess B12 may feel a little similar to taking excess Iron. B12 isn't a catch all for fatigue, you need to ensure you have adequate levels of vitamin E, folic acid(Folate), magnesium and iron for that (folic acid has some similar impacts on the body to B12 so getting the right combination of the two is important, excess of either can mask deficiencies in the other). Vitamin B6 is also important in small doses, however if you are taking more than 12mg per day from all supplements you are probably overdosing (I take 6mg myself) and may be causing peripheral neuropathy (impact is gradual over time). IF you 'need' more than 150mcg B12 a day and you are not unfit chances are B12 is not your problem unless you have a medical condition that your doctor advises is best treated with B12.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got lunge cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
Thank you! For taking the time, to provide much needed info. My problem is macular degeneration, I’m trying to keep eyes healthy with vitamins. God bless for all u do❤
A cup of organic blueberries 🫐 a day and high does DHA supplement reversed my Macular Degeneration, I use Nordic Naturals DHA and you want to keep it refrigerated once opened
Don't take B12 supplements but my B12 levels are always high. Recent blood test showed 808 pg/ml. Lab range was 197-771. Doctor said asked if I took a supplement or more likely due to a high protein diet.
Someone in the comments was asking if there was more pain as neuropathy healed. Unknown if this is universal, but in 2010 I suffered from Guillain Barré Syndrome (Miller Fisher Variant) and had a lot of neuropathy in hands and feet, plus a few other places. I took benfotiamine and methyl B12, along with some other nutrients. The onset was in May and I only got rid of the double vision in mid-July. Neuropathy in my hands kept me from working till mid-October, when I was able to start again even though I still had some neuropathy. I have just a few small places left. I did not suffer pain as the nerves healed, though they did so very slowly. I could not tell that there was any improvement day by day, but if I looked back a week I could see the progress. This TH-cam makes me wonder if I could rid myself of the last couple of places by doubling or quadrupling my intake, which has been 1 mb. of methyl B12 a day, sublingual. I also was easily confused and sometimes anxious for over a year, even as I seemed to have recovered, which suggests to me that it took awhile for the myelin sheath in my brain to heal.
Thank you, I always hesitated, how much should I take Vit. B12. It is so important, that there is not too high a dose, because we can urinate the exceeded dosage. 💌
Omg! Thank you. I have been taking 5000mcg I'm 75 with heart tissues. I took that dose for years...my Dr took b12 test and said I had too much..I went on a much lower dose and felt worse..I'm back on my 5000mcg...but it will take time to make me to feel better.
So you are looking for some excuses and support to justify your unusual intake that your own doctor said no good, instead of trusting the work of thousands of experts who set the guidelines and normal range of blood levels of B12?
@@hn5460 In the UK many doctors do not care about anyone that starts using supplements - if there is no money in it for big pharma then doctors will down-play it big time. We do not even get B12 or pretty much any of these values in our blood tests here :(
Hello doctor! Thanks for the great video. I have a question about B12. My wife is pregnant in her first trimester. She’s taking a prenatal multi vitamin with 150 mcg of b12 - it’s two forms - methyl and adensoslyn (Mecobalative R). We just found a Johns Hopkins study linking high levels of b12 in pregnant women to Austism in children. There was a fairly high correlation - p < 0.05. Would it be better to avoid high doses of b12?
Everyone who is taking metformin should also take a B12 supplement, Metformin can and often does reduce B-12 and there is no reason not to take the B-12 as a precaution to help prevent low B-12.
Yes the medical doctors keep telling me my serum B12 is too high. The cellular assay says I am still insufficient at 3000-4000 mcg a day. Two places absorption matters, the gut and the cell.
Enjoyed your presentation on B12. Very precise and to the point. Especially like that you had all the numbers to go with your recommendations. What is one of best supplements of B12 on market. Some brands use fillers and that item not as true to work as other purer supplements. Thank you for your advise.
LOVE THIS DOCTOR. UNLIKE OTHERS HE JUST GIVES INFO WE NEED, NOT PUT US TO SLEEP TRYING TO THROW WORDS AROUND OF NO VALUE. THANK YOU, DOCTOR. I GOT INFO I NEED.
Awesome video… way more informative than any neurologist I’ve seen has been. … a few questions… what would be a revolutionary subject to make a video addressing would be… what damaged nerves feel like if they’re healing (regenerating). I would imagine it’s a slow process. While making all the lifestyle changes to heal, does one have pain for months or years and wake up one day and the pain is gone? Does the discomfort fade very slowly from severe to mild to hardly noticeable? Does the pain (discomfort) SEEM to get worse before it gets better? Does the healing from nerve damage literally happen in reverse (as in if it started in the toes and made it to the calves, then the healing from it feel like it started in calves and ended in the toes)? Is healing from nerve damage as individualized as the suffering from it is? Hope you all consider this for a video subject. I can’t find anything on the internet; only material explaining the progression of the disease. Thank you very much.
WOW!!! This would make an incredible video. These are all the questions we get asked. I can't believe we hadn't thought about it, but so glad that you did. This is definitely going on our production schedule. We'll try to get this out in June's production. Thanks so much for the suggestion.
@@1truthseeking8 taking methyl B12 as a sublingual tablet bypasses the stomach absorption and therefore the need for intrinsic factor. It goes straight into the veins under the tongue.
My B12 blood level revealed 2000 mcg, which was high. So my doctor recommended I stop supplementing. Also, while the levels were high, I had migraine headaches and urinated dozens of times a night. Also, I experience severe neuropathy in all my limbs. However, since reducing the dosage, those systems are less. As well I read that too much B12 increases cancer risks.
My B12 Levels have always been raised despite suffering from a Compromised Immune System (due to past work-place exposure to toxins!) being on a semi-veg/pescatarian diet & with no B12 injections
I have a level of more than 2000 when supplementing with B12. My GP asked me to stop taking, commented that too high is no good. I stopped taking it for about two months, the level rapidly dropped down to 700! I doubt whether to continue to take or not.
Thank you for this helpful video! I was low on B12 off and on mostly off. Been on it idk for one year consistent and prior a little. My recent bloodwork showed high but now I want to discuss this info with my neurologist perhaps we may still need to increase it. And I’ll mention this to my cardiologist/and neurologist for the brain. I had a stroke on New Year’s Eve 2023 at 56 I was taken aback by this. I may actually need more B12 as I suffer now from neuropathy of the feet. Thanks again for this helpful video!
This is helpful guidance. I suffer from CFS - poor muscle control. I used to take B.12 in a small does with other vitamins. Recently updated this to 500 mcg and I must say there is an improvement in my muscle tone. thank you.
Thank you so much for your helpful video to clarify my long time questions regarding supplementation of B12. Should B12 be taken alone or should it be taken with folate to make it effective?
Wondering about too much of something and would appreciate your thoughts. As a diabetic I've experienced diabetic neuropathy for the past 5 years with numbness to mid calf. Most recently I'm expiencing significant difficulties in walking and am pretty much constantly tired. Past month I've been using benfotiamine without any benefits, but noticed on a couple of occasions that my condition worsens if I eat more than 6 slices of bread in the day. Does the bread react in any way such as interference with vitamins B?
Hi Michael. Yes, the bread (and all complex carbohydrates known as starches) will cause your glucose levels to shoot up. It will be extremely difficult for the Benfotiamine to stay ahead of the game. You need to adopt a ketogenic diet with intermittnet fasting. This is key. You will also need more than just benfotiamine. You will need ALL of the vital nutrients for nerve repair. I'm including 2 links to my video that you definitely need to watch: th-cam.com/video/wPruq49-ksU/w-d-xo.html th-cam.com/video/dKMPMPJM4JY/w-d-xo.html Also, watch these 2 videos on reversing diabetic peripheral neuropathy: Part1: th-cam.com/video/ks-WJD3WOjs/w-d-xo.html Part2: th-cam.com/video/pnOIvXW9Qyw/w-d-xo.html This will put you on the right track.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
@@NerveDoctors I just upped my 5000 McG to 10,000 McG due to this video. Almost a full body neuopathy caused by levofloxacin. I'm the one you've been corresponding with , Christopher Kording. I'm loosing hope honestly though, very depressing disorder.
@The Nerve Doctors As someone else commented , my labs showed above normal B12, I felt fine. She asked me to go off it to make sure wasn’t symptom of something serious like cancer . Levels went down to normal range. But now I’m having muscle joint nerve pain again , so taking more but was scared because worried labs would be too high. If we excrete excess, what is causing high lab levels and is this a concern . Could it just be normal for me to be high , are labs truly good measure . Thanks so much!
Fasting can help with many nerve issues. Some benefits of doing occasional extended fasting: High blood pressure is lowered to normal levels very quickly while fasting. Fasting restores NAD+ to healthy levels. Vitamin D plasma levels are increased as fasting improves metabolic health, and vitamin D in turn increases autophagy. Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. It will also remove any 'foreign material' like spikes that are not supposed to be there. Whether natural or unnatural in origin.. Fasting increases nitric oxide release. Telomeres are lengthened and fasting also increases anti-aging Yamanaka factors. Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body. Reflexes and short term memory are increased. Fasts from 36-96 h increase metabolic rate due to norepinephrine release! After 72 hours or more fasted, your body recycles up to 1/3 of all immune bodies, rejuvenating your entire immune system. This helps prevent the onset of new autoimmune conditions, which develop through a leaky gut and damaged immune system. Fasting can help with MS, Depression, BPD, Autism and seizures. Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer. Blood sugar and insulin are lowered when fasting, allowing white blood cells to move more freely throughout the body and do their job. Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue! The obese will lose extra tissue like loose skin while fasting, but the skinny or frail will have increased growth hormone release than the obese, which helps to make more lean tissue and reduce frailness. The hunger hormone ghrelin also lowers with extended fasting and rises from dieting. When you move out of MTOR your body shuts down the building blocks of the cell required for viruses to replicate. What breaks a fast? Anything with protein or carbohydrates in it will break a fast. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many meds are dangerous to take while fasting. Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone. Fasting also increases insulin sensitivity, which helps with muscle building. Fasts of 36-96 will not affect short term female fertility or affect menstrual cycle. They also may increase long term fertility, especially in women with PCOS. Fasting reduces pain and anxiety by stimulating the endocannabinoid system in a similar way to CBD oil. Fasting very quickly reduces leptin resistance, which impairs immune function. One day of fasting can cut your leptin levels in half and gets your immune system working properly again! Stomach acid is reduced over time while fasting and can allow for the healing of treatment resistant ulcers. Some patients may need continued acid reduction medication while fasting. Does the body preferentially prefer glucose as a fuel? No. Except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose. Fasting stimulates the AMPK complex and activates autophagy. Lowering insulin via fasting virtually eliminates chronic inflammation in the body. It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency. Increased mitochondrial function also has the added benefit of increasing your metabolism, fighting infection and cancer prevention! Fasting releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. This can help a great deal with diseases like MS, peripheral neuropathy and Alzheimers. When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with. Fasting also increases telomere length, negating some of the effects of aging at a cellular level. When you fast, this stimulates apoptosis in senescent or genetically damaged cells, destroying them. Senescent cells are responsible for many of the effects of aging and are a root cause of the development of cancer. A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs. Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia. Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. If you experience extreme symptoms of some kind, especially dizziness or tremors, then simply break the fast and seek advice. Resources: www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/ www.ncbi.nlm.nih.gov/pmc/articles/PMC7607739/ www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/ pubmed.ncbi.nlm.nih.gov/23408502/ www.amjmedsci.org/article/S0002-9629%2815%2900027-0/fulltext europepmc.org/article/MED/22402737?javascript_support=no onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2265.2005.02288.x www.nejm.org/doi/full/10.1056/NEJMoa012908 www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/ www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf n.neurology.org/content/88/16_Supplement/P3.090 www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/ clinical.diabetesjournals.org/content/36/3/217 pubmed.ncbi.nlm.nih.gov/20921964/ www.sciencedirect.com/science/article/pii/S0005272806000223 pubmed.ncbi.nlm.nih.gov/6859089/ www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/ www.clinicaltrials.gov/ct2/show/NCT04375657 www.cell.com/cell-metabolism/abstract/S1550-4131(15)00224-7 repository.upenn.edu/cgi/viewcontent.cgi?article=1537&context=edissertations www.ncbi.nlm.nih.gov/pmc/articles/PMC1779438/ pubmed.ncbi.nlm.nih.gov/2518860/ pubmed.ncbi.nlm.nih.gov/29727683/ www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html www.ncbi.nlm.nih.gov/pubmed/10859646 pubmed.ncbi.nlm.nih.gov/25909219/ www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue pubmed.ncbi.nlm.nih.gov/28235195/ www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/ pubmed.ncbi.nlm.nih.gov/7714088/ pubmed.ncbi.nlm.nih.gov/31890243/ pubmed.ncbi.nlm.nih.gov/15522942/ faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10 www.biorxiv.org/node/93305.full www.ncbi.nlm.nih.gov/pmc/articles/PMC5895342/ www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/ www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart www.ncbi.nlm.nih.gov/pubmed/25686106 pubmed.ncbi.nlm.nih.gov/21410865/ www.ncbi.nlm.nih.gov/gene/25712 pubmed.ncbi.nlm.nih.gov/23707514/ www.ncbi.nlm.nih.gov/pubmed/24905167 pubmed.ncbi.nlm.nih.gov/31877297/ www.cell.com/cell/fulltext/S0092-8674(19)30849-9 pubmed.ncbi.nlm.nih.gov/27569118/ www.ncbi.nlm.nih.gov/pubmed/10232622 academic.oup.com/ajcn/article/81/1/69/4607679 www.sciencedirect.com/science/article/pii/S1931312809002832 www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/ www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/ www.ncbi.nlm.nih.gov/pubmed/23876457 www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/ www.nejm.org/doi/full/10.1056/NEJMc2001176 pubmed.ncbi.nlm.nih.gov/20102774/ This list compiled over years of research by the user known as Pottenger's Human on youtube but feel free to copy and paste this anywhere you like, no accreditation needed! My channel will always contain an updated version of this list of fasting benefits on the community tab. I also have playlists on fasting and health topics.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got lunge cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
I managed to get B vitamin poisonoing from drinking 1 - 2 cans of RedBull for half a year because it helped me when I had extremely low hemoglobin in the blood. It took 4 months of no more energy drinks before I started to feel normal again, it was absolutely horrible feeling sick and nauseous with only a few hours a sleep every night for months. But doctors say my kidneys have reduced function.
12/2024. Most websites say that Red Bull contains under 2 micrograms of B12. 5 Hour Energy starts at 500 mcg. I don't think Red Bull did anything but give you sugar and Caffeine..
I dont know. Cruising YT there is an absolute cesspool of conflicting info on B12. Its infuriating. This doctor says its safe whatever dose you take. The problem is what do you do when b12 makes you sleepy and lethargic ? There are even health -care amateurs claiming that cobolamin can build to toxic levels if the b12 uptake is incomplete due to low stomach HCI and Intrinsic factor. Therefore - Toxic (can cause anxiety and lethargy all day long) The sleepy and lethargic reaction is very common. There are tons of threads on Reddit about it. So. ITS NOT SAFE ! It does matter how,when and how much you take . Just keep it in mind.
The daily amount needed for a healthy adult is 2.4 mcg. My sublingual B12 is 500 mcg. I'm 76 and far from healthy, but my last blood test showed a 900 reading. A doctor friend described it as Wow. I have invested in a pill cutter. !
There was a semi recent study that linked high levels of B6 and B12 supplementation to a 3-4X risk of lung cancer. How does that play into all of this?
Not well. In fact there are multiple studies finding increased risk of lung cancer associated with B12 but none showing causation as yet. Not hard to find these with a bit of googling. Some of these studies are with very large number of subjects too. Probably best to compare the typically high doses in these studies with what one’s doctor might be recommending and weigh up risk/benefit after discussing with the doctor.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got lunge cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
3 times Doctors have told me to take B12. 3 time after a week of taking it I got light headed so bad I thought I'd pass out so I quit. This latest episode had me in the ER were they said I had irregular heart beat....How can you say there are no side effects? I was taking 1000 MCG tabs once a day of Cyanocobalamin. Is the other one that beings with an M...forgot what it is......but it one better than the other. I'm done with B12. Also is it bad with other meds....I also take Lisinopryll and hydrcloroziodie Thanks
Toxicity induced by multiple high doses of vitamin B12 during pernicious anemia treatment: a case report Context: The clinical consequences of excess vitamin B12 induced by multiple oral doses of cyanocobalamin are not well-known. Case details: A young woman was treated with multiple daily doses of 1 mg of cyanocobalamin for severe pernicious anemia. After a total dose of 12 mg, she developed acne, palpitations, anxiety, akathisia, facial ruddiness, headache, and insomnia. She improved two weeks after stopping the drug. There were no sequelae nor complications. Discussion: Although these symptoms of cobalamin toxicity were unexpected and unusual, the case reminds us that the administration of any drug is not entirely safe.
Are Methylcobalamine the one you’re thinking about? I would check your B1 levels if I were you. Those can be the symptoms of wet beriberi. If you suddenly increase one vitamin or mineral the demand can increase for others as well. If you’re on the edge of a B1 deficiency supplementing with a large dose of another vitamin can push you over the edge. Ask your doctor for a 'Whole blood thiamine testing' and not a serum or plasma.
After 2 doses of Methylcobalamin B12 injections (2 weeks apart), my B12 level went from low-medium (320 pmol/L) to absolutely way to high (1132 pmol/L) normal range is 200-600 pml/L in Canada. This blood test reading was 8 days after my 2nd injection. Question: How long will it take for my body to get back to a normal B12 range. Praying this hasn't damaged me permanently. I had a headache and strange anxiety systems, followed by total insomnia.
If you take injections for pernicious anemia or B12 absorption issues, your B12 levels will be >1,500 if you inject monthly. But don't worry those numbers really don't mean much. You're not using all that B12. Most of it is getting eliminated through urine. It takes months for it to go back down, And by that time you'll be do another injection, so don't worry those numbers are not going to affect you. Doctors shouldn't even be testing your B12 if you're on injections. If you have a B12 deficiency and you have to inject B12 monthly, weekly, daily, whatever it is, it's going to raise your B12 levels for the rest of your life. You really can't go by those numbers anymore once you start injecting B12. They become obsolete. Methylcobalamine is the pure form of B12. Our bodies convert B12 into methylcobalamine. Cyanocobalamine and hydroxycobalamine need to be converted in our bodies. Which is the natural process. Some people can't tolerate methylcobalamine. I use hydroxycobalamine or cyanocobalamine because it's readily available in ampule forms, where methylcobalamine is only available in powder form and has to be mixed with injectable saline. Methocobolamine can cause insomnia, can make you break out with acne, and can give you quite the headache and anxiety. But that is the worst of the symptoms and the worst that can happen to you. Cyanocobalamine and hydroxycopolamine usually don't cause those side effects. One time I bought the powder for methylcobalamin, and my pharmacist miscalculated the dosage so over 5 days, i injected enough for 30 days. I had terrible insomnia and a terrible headache but after it started to wear off a little, I had no pain in my feet, my body felt fantastic for the first time in a very long time. That was a mega dose of methylcobalamine. The methylcobalamine is an excellent B12, but some people can't tolerate it. And you can't get it in single dose ampules, or I would be using that everyday! multi dose vials are susceptible to contamination. I think once you get used to methyl cobalamine, the insomnia and headache etc will get better. If your body was starving for B12 for a very long time, and you start injections, you get what's called reversing out symptoms. That's where your body starts reversing out all of the symptoms your body was going through from not having B12. When I first started injecting B12, I hadn't had B12 in my system for probably more than 25 years. So when I first started injecting my liver really started to hurt and my stomach started to hurt and all of my body was very sore. The neuropathy got so bad I was crawling to get around, not to mention the brain fog, the inability to find my words and form a sentence, I was in pretty bad shape. But then it started to get better. So if you've got pernicious anemia or B12 deficiency absorption problems, And you've had a deficiency for a long period of time, these symptoms can get quite painful. So when you start taking B12 and it starts to reverse those symptoms and starts to heal them your body will go through some painful changes. But it does get better and it starts to even out. I still suffer terribly though from neuropathy and weakness in my legs because I have macrocytic anemia. And so far I haven't been able to get that to get any better. I'd say I'm about 40% better in general than I was last year, and that might be as good as I'm going to get. So yes methylcobalamine can cause headache, insomnia, acne and anxiety, because it is the purest form of B12. And some people can't tolerate it. But it is the best form as far as helping symptoms goes in my opinion. It's just not readily available for self-injecting. The next best form is hydroxycopolamine, that's what they use in the UK, and cyanocobalamine which is what we use in the United States.
@@18eleanor They said TO AVOID, and NEVER take Cyanocobalamine, as it is the bad form of B12 as it has Cyanide in it. They only suggest the other forms especially Methylcobalamine. Thank you for sharing your experience, I learned a lot from it, Thank you, Blessings!
I just want to reiterate here that you cannot OD on B12! If you have to inject B12 your B12 levels will always be >1500. That number is completely obsolete and means absolutely nothing and the fact that any doctor is testing a patient's B12 after an injection is an idiot. They should know that you cannot test B12 after injections because the numbers will be through the roof. And they will be for the rest of your life and never never never never never accept your doctor saying you don't need any more B12 if you have pernicious anemia if your numbers are greater than 1500. You need B12 for the rest of your life daily weekly monthly whatever it is that you need it, you need it for the rest of your life and your numbers will be greater than $1,500 forever. That number is obsolete it means absolutely nothing. You're not using all that B12 your body will eliminate it and pee it out. It does not affect you in any negative way whatsoever. Do not wait for your numbers to go down before you have more B12 if you have pernicious anemia or B12 deficiency that needs injections. If you have to have injections you have to have them for the rest of your life. Unless you're a vegan or vegetarian whose doctor just wants to get you quickly up to a good level they might inject you for a couple of months and then they will go back down and tell you to take sublingual B12. But people with pernicious anemia not caused by a diet, need B12 every single month if not every day for the rest of your life. Do not listen to any doctor who says your B12 levels are too high because you've been injecting B12 that doctor doesn't know what he's talking about. And he needs to go back to school. Those are the doctors that are ruining everything. Doctors have about 15 minutes worth of schooling and medical training on supplements and nutrition. They know little to nothing about pernicious anemia treatment and B12 deficiency. Everything I'm telling you I have had to learn through the pernicious anemia society. They're the ones who know what they're talking about they are the pernicious anemia society they know what pernicious anemia is how to treat it and what the truth is. Please visit the pernicious anemia society.org for the truth about vitamin B12 deficiency pernicious anemia. It is imperative that you do not listen to a doctor who tells you your B12 levels are greater than 1500 after he injects you with B12. Stupid doctor Any side effects you had from the B12 injections are normal It's because your body was starving for B12. It's like putting your foot in a clear lake and touching the bottom and having all the mud and muck start swirling around that's kind of what's happening in your body Your body has been broken and depleted of oxygen red blood cells and B12 so as you start pumping that back in your body's almost like a balloon feeling back up and all the wrinkles are coming out. And then once you get to that point where you're stable and everything is back to normal your body will start working better. But until it gets fixed it's going to go through a slightly rough period of time trying to repair itself. That's all your body is doing is getting used to having B12 that it has been depleted of for decades. It's just rejuvenating itself and it's trying to fix itself. That comes with side effects. Insomnia anxiety a headache. And things can get slightly worse before they get better. But that's just called reversing out and it is simply your body coming back to life. That is all it is. If you don't believe me please visit the health unlocked forum and ask them all the questions you want or go to the pernicious anemia society.org please Google those things and please ignore the doctor that says your B12 is too high after an injection. You need a new doctor. This doctor does not know what he's talking about. There is nothing to be afraid of with B12. It is a water soluble vital Ammon that your body needs. Whatever excess B12 isn't used by your body it will be eliminated through your pee. You will feel better soon. And the fact that you feel so badly I don't think one injection is enough for you a month. You sound like you may be somebody who needs at least weekly injections. But you're not going to talk your doctor into doing that for you. Very seldom can you get a doctor to understand that you need B12 more than once a month.
That reference range you stated Jim is for healthy people, if you have a deficiency you're not healthy, it needs to be a lot higher for you to feel well .
And... is small fiber neuropathy a different monster than large fiber neuropathy; or do they go pretty much go hand-in-hand? Small fiber neuropathy (sensory nerves) in the hands and feet seems to be reported about as if it's a more frustrating to treat than large fiber; unless I'm missing something.
I copied your last message from yesterday and have added this to it. I immediately went over it with Dr. Coppola, who also agreed it was a brilliant topic for us to cover, so we've bumped another topic that we had scheduled for June and will be replacing it with this one. We should release this video on this topic by the end of June. Thanks so much for your suggestion!
Agreed that we need more than RDA, but ODA numbers vary wildly depending on which source you use... It is incredibly hard to determine ODA as it is so dependent on individual factors, and the state of the research is constantly changing... I recommend taking ODA numbers with a large grain of salt. In my humble opinion, it would be better to simply try and get as much as you can of all essential nutrients while still staying below the NOAEL ( No Observed Adverse Effect Level), unless treating a specific condition under the supervision of a physician. It may still be necessary to further limit your intake if you have a sensitivity or allergy to the nutrient in question and must limit your intake further, or are taking medications that may be effected by high doses of said nutrient. That said, cobalamin (B12) is INCREADIBLY safe... So much so that there is still no firmly agreed upon NOAEL for it, with the Scientific Committee on Food stating “…there are no clearly defined adverse effects produced by vitamin B12 that can be used to define a LOAEL or NOAEL, which can be used as a basis for deriving an UL” . However I am aware of two recommended NOAELs based on the synthetic form cyanocobalamin based on rat studies, with suggested NOAELs of 100mg/kg/day and 500mg/kg/day respectively... yes that is mg, not mcg!! and the natural form Methylcobalamin is considered even safer.... However, this does not mean that you may not have an individual sensitivity or allergy to B12 that may lead to skin rashes, GI upset, or even anaphylaxis, even at much lower doses... So like everything, while this is a VERY safe vitamin for most people, don't start mega dosing blindly, work your way up to higher doses slowly, and even then just in case, it is probably best to keep your daily intake under 2000-3000mcg/day unless under the supervision of a physician.
Nice one Michael, caution is always needed, just look at some of the comments here like Jim Doukis and Connie Waterman, it just goes to show that there is no one size fits all answer.
Being a vegetarian I bought Solgar B complex with 2mg of B12. That was listed as 83,000% of RDA in one ML eyedropper. I did one once per week. At that week or the next I began to have TOTAL insomnia! Checking the web confirmed it could. I stopped and soon I was sleeping normally. I also read that the liver stores it a long time so likely can accumulate. 😮 I guess it could have been some of the B complex too.
Did you take it right before bed? If the supplement contained the B12 form Methylcobalamine it’s no wonder you got insomnia if you took it before bed or late in the evening. Most people will get a bit hyper and agitated on Methylcobalamine.
Before listening to this video, I listened to the TH-cam video called, "Is too much B12 bad." (Can you take too much B12.) He says the opposite of Dr. Coppola. He says that it is very possibly linked to lung cancer and other cancers. What do you think of the Trainers cancer view?
So the optimal daily allowance for general good health is 10,000 mcg daily - but if you need nerve repair, then you need at most 3,000 mcg daily? Does this make sense to you? It’s hard to imagine a more confusing video.
I think you missed the point, he was just comparing the RDA and the ODA which is what they say you should take . Remember he said everyone is different so the 1500-3000 mcg is the overall recommended daily amount for everyone . So if you drink or smoke or have something else going on you might need more , just like the case he was talking about where they gave the patient 60.000mcg daily.
With oil-soluble vitamins, there is always a risk to the liver if you take too much. D,E,A,K are the vitamins you must be careful not to take in excess, unless under the care of a professional. Excesses of water-soluble vitamins are easily dispose of through the kidneys. For those, it becomes more a cost/benefit analysis of throwing away excess vitamins.
I have had peripheral neuropathy in my feet for about 3 years. I currently take 500 mcg. Vegan Methylcobalamin in an organic spray once a day. I usually take 2 sprays. Should I take maybe 3 or 4 sprays instead and should it be sprayed under the tongue? Thank you!
After seeing the recommended 10,000 mcg to be optimal I have a question, (I’ve been on B12 for a few years (was deficient at one point due to vegetarian diet for about 8 months) and noticed my levels are continually above the “lab range”. Most of the time 1200-1400. I will remove the supplement (2500 mcg daily) to lower it, but then I start to have deficiency symptoms. Is having above the normal serum levels ok if I feel I need it? And do some humans just need more?
Hi B4L. I just filmed a whole video on this. Watch this weeks video. It will be released on either Thursday or Friday of this week on B12 deficiencies. It completely explain why your lab values read normal while you show signs of deficiency. Blessings.
When I had my stroke they told me all my labs were good except that I had almost NO B12 in my system. I asked him (the neurologist) what would cause that ?? He really didn't answer me except to say take it every day. You will just pee out what you don't need.
If you are not vegan then you need b12 injections with low level . Taking b12 supplements will not help due to malabsorption issues Take folic acid with the injections to heal at cell levels and multi b vitamins heals cognitive decline
Answer to prayer. I recently had routine blood work completed. B12 Results @ 1,383, and i was concerned it is too high. From what i gathered from your post is that my body is in an optimal state of repair. It now makes sense for the less inflammation, more energy ( I can go more than 3 hours cleaning) etc.
Thank you kindly. 🎉🙌
My husband’s just came back high too, over 1,100. So sounds like we shouldn’t worry. He was taking Nerve support and Bcomplex.
@@windy42305It’s very common to have high serum B12 when you have a B1 deficiency. If he’s deficient in B1 he can have sufficient and also high serum B12 without utilizing it, a so called functional B12 deficiency. I would definitely add some more B1 supplements like Benfothiamine 3-400mg to my routine if I were him. The B-complex is not enough if he’s deficient in B1.
When I was 65 my primary car physician during an annual health visit did a quick sensation check on the bottom of my feet. I could not feel it. My B12 blood test was normal although on the low end of normal. She recommended take a B12 supplement with 2000 mg. I did and within 6 days my feet had returned to pretty normal sensation. They continued to improve for more than six months. I continued taking B12 and will for the rest of my life.
mg or mcg?
I have ideopathic peripheral neuropathy and also had normal b12 levels but low normal. I’ve been taking 2000 mcg of b12 daily for 3 weeks now and my symptoms have diminished significantly. I found this through my own research. My neurologist never mentioned it.
@@SD-co9xe I'm glad to hear that. My chiropractor told me to take vitamin B. I bought a B complex that had only 100 mcg of B12. After further research, I realized I could probably use more. Do you take 2000 mcg all at once or split it up during the day, taking 1000 mcg of B12 at different times of the day?
All at once. My GP says it’s a water soluble vitamin so low to no risk of too much.
got to be mcg @@goldenarm2118
I am 65 and eat very little meat. I just bought B12 supplements today and so glad I came to this channel. I plan on starting with 1000 mcg daily.
Make sure it is the Methycobalamine variant and not Cynacobalamine variant. Later one is poisonous at high doses.
@@free_soul9154
Adenosylcobalamin is another form of vitamin B12 that is bioavailable.
@@free_soul9154better yet get a mTHFR test/homocysteine levels. Everyone is different Methylated B's has negative sides for me.
Un methylated b complex is great for an over methylator because of the gradual conversion.
80 /20 gtound beef its medicine get some
Take liquid B12 it gets in the bloodstream
At the age of 35, one day at a very stressful job, I suddenly lost the feeling in the tips of my toes, fingers and the ability to taste also having lost the feeling in my tongue. I also developed a splitting headache, lost a lot of weight and noticed my hair falling out. My doctor instinctively tested for my B12 levels. My levels were so low, that they did not register on the test. She put me on weekly injections and was concerned if I might have developed permanent nerve damage. She said also that because I had premature grey hair, that it was very luckily that I did not absorb B12 well. Luckily, after 6 scary months, I gradually regained all the feeling back with no damage. More than 10 years have passed, and I make sure I take B12 almost daily now.
Which brand b12 tablet sir
@@redpepper8913 natural factors is the methyl B12 I take. It's a well tested product too
@@junechris but it causes loss of appetite to me.... Do you have any problem like this sir?
@@redpepper8913 no, not at all. That's kinda wierd.
@@junechris thanks for the reply 🙏
I started with 1000mcg Methylcobalamin, it was ok, a nice boost to me day. But recently I found some 5,000mcg that dissolve under your tongue. I take them after breakfast and boom I am energized. I am recovering my an illness that prevented me from my daily three mile walk for 5 months, now I am quickly working my way back.
@@kennethward4985 what brand please?
What was the make/brand of the 5,000mcg one please?
@@Nexus2UAll I believe they were talking about this from Amazon.
Horbäach B12 Sublingual Methylcobalamin
@@Nexus2UAll Kirkland (Costco)
Always check the excipients! It might turn out to be a shock.
Thank you once again Dr Omole on TH-cam for this information. Since following you (for some years now), my kidney stage results has decrease from stage 3 to stage 1. You saved me from dialysis. Thank you and please keep the videos coming!! God Bless...
I had to take 35,000 mcg of B12 everyday years ago for 6 months, I then started to reduce it and over a year I had to stabilize at 15 to 20,000 a day for almost a year I’m now at 10,000 a day . I’ve had 5 low back surgeries and 3 neck surgeries. I was also exposed to benzene severely in 88 . And my adrenal glands are enlarged to about the size of a half dollar. It was to the point I didn’t want to get out of bed or take a bath . My family didn’t understand they thought I was just lazy and in self pity. I was praying and praying for help but drs didn’t help . I was woken up one night around 3am to go and research adrenal fatigue. And the video said to take but loads of B12 so I started with 2,000 and each morning I doubled it until I was back up and moving around. It took about two weeks. I was back my garage doing things . I hurt because of my past injuries I’m not on any pain meds and I don’t let the pain stop me as much as it used too . I recover and hit it again, I recover and repeat. I was 27 when exposed to benzene, I’m here because of my prayers and Gods blessing, I was 21 when I broke my back and I was 43 when I injured my neck that was the one the took me out of work. I’m now weeks away from 64 . I still do things but much much slower. But I’m persistent until it’s done . I weld build things do woodwork and I a retired electrician. Each day is a gift even in the pain and believe me it’s painful. Some days I can’t walk , god ask us to praise him even in the valley as well as the mountain top and I can tell you without him I couldn’t make it in those valleys. You would be amazed what he will do for you in just praising him on those difficult days , God is Good ❤ 1-1-25 to add drs are now attempting to send me to Methodist hospital in Houston for test , they finally looking into the masses on my R/ kidney and adrenal gland mass . After the damage is done . The pain through out my body is horrible. If it hadn’t been for god I doubt if I would have made this far. God lead me to B12 and he will continue to lead me until my last breath. The tumors has caused my heart to enlarge inwardly over time , drs refused to acknowledge the problems from the adrenal gland and they didn’t address those issues.
Why did God let you suffer in the 1st place? Ridiculous
God bless
I'm in o😊
Bless you, Thank you for sharring! God is good everyday!!
@@judykelley5023 Drop dead, Trumper
Dr thank you for explaining things very well which no hospital or doctor tells.
So happy to help.
I have problems having energy to do things and thinking faster. Sometimes I think I have depression and mood swings. And B12 has helped me feel normal, energized, positive.
@H-jb4tf thank you for the advice. I try to eat more vegetables now, becus I hardly did growing up…I do noticed when I eat too much carbs I feel so tired.
@H-jb4tf Not true. B12 is mainly sourced through meat and shell fish.
B12 is not an anti depressant.
You can become depressed through B deficiency so injections and tablets will help@@jerryodonovan8624
BI2 ....works on mood
Excellent valuable information. Thank you for educating people with the truth to achieve optimal health.
Thank you so very much, Rich. We truly appreciate the feedback and kind words. Have a wonderful day!
Thank you I was taking about 10,000mcg per tab I two little tablets because I needed the energy without taking caffeine. I was worried I would might be taking too much. Thank you again.
Thank you so much for all your blessings and good job 👏 🙏
Thank you for this information and explaining the risks and benefits. My doctor doesn't think B12 levels are not a big deal so I am in this on my own. YT vids are helpful but reading the research lit answers many of the questions you have answered. Again, thank you.
Many physicians are not dialed into supplements as essential to older people. They like medicine to treat your high illness, like blood pressure, high cholesterol, etc.
If you’ve ever had Trigeminal Neuralgia, an excruciating facial nerve condition that’s nicknamed “The Suicide Disease,” you wouldn’t think anything is too much when it comes to B12. Because of sublingual Methylcobalamin taken at 5,000 mcg dosage, my TN completely disappeared! It was nothing short of miraculous-keeping me from having to have a scheduled MVD surgery (brain surgery) at UCI in Irvine, Ca. Three years later, I am still symptom free! I still take sublingual 5,000 mcg every two days just to make sure the TN doesn’t come back. Back in the 50’s sublingual B12 was widely used for TN and MS as a first line of treatment. But then Big Pharma arose and… well you know the rest of that story. It’s an all-too familiar one. 😮
Interesting to read your comment. I have intermittent TN and have monthly injections due to low absorption issues. I wonder if I should get my dose increased.
I cannot even understand how b12 can heal cluster/similar.
I use the highest one CAN use without making a issue for the rest of the body .
Because , its not like one doesnt have a limit ?
I use triptan and o2 (8 to twelve bar/high pressure) against cluster /suicidal headache.
I couldnt make it without,tbh.
No matter supplements.
It IS a infection on the back of the eye , right ,so one needs triptans/ergotamine,to contract bloodwessel that is swollen ...i think?
Its the only thing that work for me. Even strong petidin/ketamin/morphin wont help.
I have tryed everything ,im sure. All neuralgica medication,supplements,botox ,nerve blokade's (waist of time). I have been offered surgery,but the high risc surgery dont often work,so...
I thought everyone with this type of headache get high pressure high bar o2 ? And nausia medication ,of course.
This type of headache is easy to spot,it makes one eye deep,bright red and swollen,and tears will flow ,constantly (and nose will run,at the same side). The patient cannot lie still , like people with migraine will do.
Its a horrible state . But it MIGHT disapear, or at least become a rare thing . So, cross fingers !
One can get nerve damage, higher risc of blood clogs and lung cancer , anemia , and so on, with to much b12.
I DO fet you want to take your chance,if your life is filled with those seizuers ,tho. They can destroy lifes,and they do. I know.
But i still wonder , dont you have ANY help from 02(it HAS to be with pressure mask,and at least 8 bar for 15 minutes, or it wont work. Normal is 2 bar ,or so...,it IS a lot. But it has to be. I use 10 bar, so i empty a bottle very fast. Has to have those big ones! ).
You dont use ANY other help for your seizuers?
Awww yes, big pharma!! That's wonderful that they gave you 5, 000mcg of B12. When they treat cyanide poisoning or malaria they give people 10,000 times the amount of B12 every day until they're better. 10,000 times. Congratulation on finding the help you needed.
I got rid of my trigeminal neuralgia with acupuncture
Thank you! Im recovering from a long period of extreme Stress and have been taking B12vand Benfotiamine...i will increase the B12 now!😊
Thanks so much Doc.God bless you for the informative videos . l fee better any time l take B12 supplements but l still feel numbness in my feet and hands .
Take all Vitamin B, they all can do a lot:) And Benfo plus Allithiamin listen to Elliot Overtone on TH-cam. Magnesiumglycinate and some adaptogens like rhodiola rosea, passion flower ( I love passion flower extract:). Greetings from Germany
Hmmm, this is information I have been waiting for, dunno how the YT algo knew I wanted to know more about Neuropathy but here we are.
So glad you found us. Welcome to our tribe!
I have high homocysteine due to homozygous MTHFR mutation. High doses of methylcobalamin were prescribed, but a few months later I had odd symptoms, including strange aches and muscle pains, brain fog and terrible insomnia. Soon after, I broke out in a bright red, full-body rash that lasted several days. The high-dose B12 was the only recent change I had made, and it turns out I am allergic to cobalt. This also explained a decades-long reaction I had had to certain types of eye makeup, which caused oozing, painful rashes. I always thought some unknown red pigment was to blame, but it was blue from cobalt. Skin rashes are one thing, but the full-body and brain problems I had with high doses of methylated B-12 were debilitating. So it's not correct to say it is completely safe at high doses. A small percentage of us will have an allergic reaction
sounds like a result of long exposure to toxic makeup
@@Lauren-vd4qe no, I haven't worn eye makeup in many years. When it used to happen with certain colors, years ago, the reaction was almost immediate. The recent illness and rash occurred after starting a high dose of B12 and it resolved a couple weeks after stopping it. If you don't believe it's possible to have such a reaction to B12 or an allergy to cobalt, look it up rather than diagnosing a stranger from afar
@@darlafitzpatrick8770 oh i think its possible dont misunderstand me.
B12 became extremely high after taking a strong dose for a short time. During seizures, I experienced a fast heart rate, palpitations, nausea, vomiting, profuse sweating and almost went into cardiac arrest a couple of times. My liver and kidney numbers were also extremely high.
@@Me-555 Yikes! My reaction was weird and very unpleasant, but nothing like that. Doctors need to realize B12 supplements can harm some people and more is not always better.
Thanks for clarifying the issues with B12 minimum and ODA it was very helpful! I did not know the relationship with nerves and B12 with which I have a problem, and know now to increase the dosage!
One thing important to remember if you want to check your b12 level for a deficiency, do not start supplementing before bloodwork as it will skew your b12 serum levels.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
THANK YOU FOR YOUR HELP
Thank you for the rule of dosage.
Didn't know there is a optimal health dosage
required.
This is an awesome video. And I am SO GLAD I stumbled across it. I was researching a prep used for vertigo, and got more info that I needed because my husband has recently dianosed dementia, at 83. The meds for dementia have horrible side effects, and I took him off them pronto. I am convinced now, that the tiny dose of B12, that the NP recommended was a moot point, especially because she failed him at every turn, saying that his 104 weight, down from 140 was nothing to worry about. It turned out to be colon cancer. I got another opinion. Now, his memory is so short, and he gets lost if he has to make more than one turn, so now, I do EVERYTHING. l fully intend to put him on a high dose of B12, and a prep, I looked into for my vertigo has a high dose. I have him on MCT oil, and Benfotiamine3, and D3, 4,ooo, plus k2. Other than the memory and directional issues, he does very well. Gets wholesome food, and good sleep, and, even though he still complains of our long walks when we were dating, I see that he does get enough walking LOL Thank you SO much, Dr., I will subscribe!
GREAT!! You just answered my questions! I have internal vibration (getting worst everyday) and it could be due to nerve damage. I hear that vit B12 would help me get rid of those vibrations but I was not sure about the dose to take. Now I can take the 5000 mcg pills I bought without any worries. Thanks sooo much! Dominique
did u take it? what happened?
@@Lauren-vd4qe I started 8 days ago and I already see a big difference...I almost have no vibration during the day and at night it's like 30% of what it was at the worst. I keep taking them for 4 months because there is a warning on the bottle saying to check with my doctor after 4 months. :-)
@@andredemers69 and avoid coffee and alcohol, they DRIVE all the B vitamins OUT of your body very aggressively but no doc will ever tell you that.
@@andredemers69 i took a 5000 mcg pill today and my ringing is about HALF in 2 hrs.
Make sure to have enough B1( benfotiamine, allithiamine) and B6 (P5P only) and methylfolate with it and very important with enough electrolytes (especially potassium)
Love this video. I started taking B 12 5,000 mcg liquid, 2 droppers full three times daily and it improved my mental focus by the end of the day. I believe we cannot get enough nutrients in our food, and we also need enough stomach acid to absorb the nutrients. Over the age of 30, our stomach acid declines. I am taking high doses of B vitamins now and can feel a big difference in energy levels. A friend of mine has horrible nerve pain and she has refused to megadose B vitamins. With this Medical Doctor video, hopefully she will now believe me.
Thanks for making this video, I was about to purchase Nuphoria Gold for neuropathy and saw it had 125,000% RDA of Vit B12 and was concerned, this video cleared that up.
Arturo So glad it was helpful. Thanks for watching!
How safe is cynocobalamin?
Most people don't have a problem with knowing how much to take. Their problem is that they use the doctor's Serum B12 test results to tell them if they are okay. They do this without knowing the Methionine Cycle the Folate Cycle and the MS enzyme that connects them. If more doctors performed MMA and Hyc tests rater than an almost useless Serum B12 test, they would have a much better idea of their Methylation and Transsulphuration status, which is what it's all about.
Thanks for this insight.
Very helpful intake 1000 updated to 1500 I can tell a difference but still get numbness at times may go to 2000
Thank you so much for the information, that’s a concern I’ve been having since my conventional doctor can’t even address after taking my blood work.
Jeffrey Rodriguez So Glad it was helpful. Thanks for watching.
Thank you tons and bunches doc for being informative and caring. I'm pushing the subscribe button now. Quality of life is my goal as a senior citizen, and so much information is vague at best. Thank you for the heads-up
Thanks!
Thank you so much for your support. Your donation goes towards further research.
Thank you for sharing your knowledge, such a great educational channel to help people's health. More blessings!
Thank you so much. Truly appreciate it!😊
Thanks Doc. I take 2500 mcg each day and feel great.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
Thanks for
this important information.
I’m going to post you constantly to my group because it’s too much work for me I’m constantly repairing my self it’s a long fight. Plus I was diagnosed then repaired..li have so many stories about my road.,
Thank you very much for getting this message out there. Is extremely difficult for patients to combat this silly misconception that doctors have about B12 overdosing. I have severe neuropathy in my feet and legs so I've been injecting two ml a day instead of one. But I would like to even do more. My feet hurt so bad. I'm going to watch your other video as well that you mentioned at the end of this video to see if I can fix my feet. Keep debunking these misconceptions of B12. Something needs to change so we can buy B12 ampoules OTC in the US and UK.
Could you maybe talk about subacute combined degeneration caused by B12 deficiency/PA and what can be done to fix the nerve damage? That would be a great video. Thanks so much
Et to the point
This is confusing. "Et" doesn't have any meaning that fits this sentence, yet someone liked it. ??
any change in your neuropathy after mega doses of b12
@@nageshnimbalkar4091 Well, it's a little hard to say. But I like to think it is, even if it's just a little bit. It seems when I'm in a flare-up, if I inject B12 directly into my thigh instead of my belly where it has to kind of get through some fat, I think if I inject it directly into my leg it's got a better chance of reaching areas of the lower extremities. And I'd like to think that it does relieve my feet from excruciating pain but doesn't eliminate it all together and it just comes right back If I skip a day. Without it, it would get worse So if nothing else it's keeping it from being like it was last year where I was crawling on the ground because I couldn't walk. It is excruciating and it's one of my worst issues from pernicious anemia. I wish I knew how to help it because it's debilitating in its running my life. B12 is all I have and I'm all I have, because doctors know nothing about this. They go home at the end of the day and don't have to worry about it but I have to live with it every second of the day and it's extremely excruciating It's a terrible disease and doctors don't know anything about it. I feel like I have nowhere to turn but myself. Thank goodness for B12 because it's all I have and at least I'm still alive, but I'm not living that's for sure, because of neuropathy. I wish I had a better answer for you. But all I can say is without B12 I would be in a wheelchair. So whatever I'm doing it's at least keeping me from that.
B12 is doubtless relatively safe in big doses, however in large doses if you are otherwise already healthy it can give you difficulties focusing your attention due to excess energy. I am not sure about B12 to treat peripheral neuropathy (if it is caused by excesses of minerals or excess Vitamin B6, ALA is a better treatment to remove the excess from your system which will lead to healing). Excess B12 may feel a little similar to taking excess Iron. B12 isn't a catch all for fatigue, you need to ensure you have adequate levels of vitamin E, folic acid(Folate), magnesium and iron for that (folic acid has some similar impacts on the body to B12 so getting the right combination of the two is important, excess of either can mask deficiencies in the other). Vitamin B6 is also important in small doses, however if you are taking more than 12mg per day from all supplements you are probably overdosing (I take 6mg myself) and may be causing peripheral neuropathy (impact is gradual over time). IF you 'need' more than 150mcg B12 a day and you are not unfit chances are B12 is not your problem unless you have a medical condition that your doctor advises is best treated with B12.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got lunge cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
Wow I was worried that my 21 mcg daily B12 intake was too high, but that is definitely not the case!!!
Thank you! For taking the time, to provide much needed info. My problem is macular degeneration, I’m trying to keep eyes healthy with vitamins. God bless for all u do❤
A cup of organic blueberries 🫐 a day and high does DHA supplement reversed my Macular Degeneration, I use Nordic Naturals DHA and you want to keep it refrigerated once opened
Don't take B12 supplements but my B12 levels are always high. Recent blood test showed 808 pg/ml. Lab range was 197-771. Doctor said asked if I took a supplement or more likely due to a high protein diet.
Thanks for your time and advice .
My pleasure. I'm glad this information is helpful. Blessings.
This information is so important. Thank you Doctor 🙏🏼
Someone in the comments was asking if there was more pain as neuropathy healed. Unknown if this is universal, but in 2010 I suffered from Guillain Barré Syndrome (Miller Fisher Variant) and had a lot of neuropathy in hands and feet, plus a few other places. I took benfotiamine and methyl B12, along with some other nutrients. The onset was in May and I only got rid of the double vision in mid-July. Neuropathy in my hands kept me from working till mid-October, when I was able to start again even though I still had some neuropathy. I have just a few small places left. I did not suffer pain as the nerves healed, though they did so very slowly. I could not tell that there was any improvement day by day, but if I looked back a week I could see the progress. This TH-cam makes me wonder if I could rid myself of the last couple of places by doubling or quadrupling my intake, which has been 1 mb. of methyl B12 a day, sublingual. I also was easily confused and sometimes anxious for over a year, even as I seemed to have recovered, which suggests to me that it took awhile for the myelin sheath in my brain to heal.
hello, were you on any prescription drugs to help with the pain during this time?
Thank you, I always hesitated, how much should I take Vit. B12. It is so important, that there is not too high a dose, because we can urinate the exceeded dosage. 💌
Omg! Thank you. I have been taking 5000mcg I'm 75 with heart tissues. I took that dose for years...my Dr took b12 test and said I had too much..I went on a much lower dose and felt worse..I'm back on my 5000mcg...but it will take time to make me to feel better.
So you are looking for some excuses and support to justify your unusual intake that your own doctor said no good, instead of trusting the work of thousands of experts who set the guidelines and normal range of blood levels of B12?
@@hn5460 In the UK many doctors do not care about anyone that starts using supplements - if there is no money in it for big pharma then doctors will down-play it big time. We do not even get B12 or pretty much any of these values in our blood tests here :(
Doctors aren’t educated in natural supplements. Only chemical medicines. 🤨
Hello doctor! Thanks for the great video. I have a question about B12. My wife is pregnant in her first trimester. She’s taking a prenatal multi vitamin with 150 mcg of b12 - it’s two forms - methyl and adensoslyn (Mecobalative R).
We just found a Johns Hopkins study linking high levels of b12 in pregnant women to Austism in children. There was a fairly high correlation - p < 0.05. Would it be better to avoid high doses of b12?
Everyone who is taking metformin should also take a B12 supplement, Metformin can and often does reduce B-12 and there is no reason not to take the B-12 as a precaution to help prevent low B-12.
And antacids
Yes the medical doctors keep telling me my serum B12 is too high. The cellular assay says I am still insufficient at 3000-4000 mcg a day. Two places absorption matters, the gut and the cell.
Enjoyed your presentation on B12. Very precise and to the point. Especially like that you had all the numbers to go with your recommendations. What is one of best supplements of B12 on market. Some brands use fillers and that item not as true to work as other purer supplements. Thank you for your advise.
LOVE THIS DOCTOR. UNLIKE OTHERS HE JUST GIVES INFO WE NEED, NOT PUT US TO SLEEP TRYING TO THROW WORDS AROUND OF NO VALUE. THANK YOU, DOCTOR. I GOT INFO I NEED.
Tanks a lot, I was really wondering
Awesome video… way more informative than any neurologist I’ve seen has been.
… a few questions… what would be a revolutionary subject to make a video addressing would be… what damaged nerves feel like if they’re healing (regenerating). I would imagine it’s a slow process. While making all the lifestyle changes to heal, does one have pain for months or years and wake up one day and the pain is gone? Does the discomfort fade very slowly from severe to mild to hardly noticeable? Does the pain (discomfort) SEEM to get worse before it gets better? Does the healing from nerve damage literally happen in reverse (as in if it started in the toes and made it to the calves, then the healing from it feel like it started in calves and ended in the toes)? Is healing from nerve damage as individualized as the suffering from it is?
Hope you all consider this for a video subject. I can’t find anything on the internet; only material explaining the progression of the disease.
Thank you very much.
WOW!!! This would make an incredible video. These are all the questions we get asked. I can't believe we hadn't thought about it, but so glad that you did. This is definitely going on our production schedule. We'll try to get this out in June's production. Thanks so much for the suggestion.
@@NerveDoctors Thanks again for the quick response; can't hardly wait.
The pain for me feels like my legs are on fire or burned.
@@NerveDoctors got any details on "Intrinsic Factor" & B-12?
@@1truthseeking8 taking methyl B12 as a sublingual tablet bypasses the stomach absorption and therefore the need for intrinsic factor. It goes straight into the veins under the tongue.
Thank you so much Dr. Coppola for this valuable information.
Mino Mokwa So glad it was helpful. Thanks for watching!
My B12 blood level revealed 2000 mcg, which was high. So my doctor recommended I stop supplementing. Also, while the levels were high, I had migraine headaches and urinated dozens of times a night. Also, I experience severe neuropathy in all my limbs. However, since reducing the dosage, those systems are less. As well I read that too much B12 increases cancer risks.
Absolue bullshit
@@fireyflower6643 Translate?
It doesn't increase cancer risk, but it feeds cancerous cells (as well as healthy ones) once you have them.
I have read that those with certain cancers had high levels of B12. Therefore, a correlation exists.
...not that B12 causes cancer. This is continually being studied.
My B12 Levels have always been raised despite suffering from a Compromised Immune System (due to past work-place exposure to toxins!) being on a semi-veg/pescatarian diet & with no B12 injections
Please speak about: "ALPHA LIPOIC ACID" and proper doses to take... THANK YOU😉👍🇺🇸
600 mg for 6 months one capsule for day
Thank you so much u helped me with all my nerve problems
Mary Seserko So glad it was helpful. Thanks for watching!
Thank you Doctor. It cleared my doubt. I am a regular user of B12 my level is >2000 pg/ml
I have a level of more than 2000 when supplementing with B12. My GP asked me to stop taking, commented that too high is no good. I stopped taking it for about two months, the level rapidly dropped down to 700! I doubt whether to continue to take or not.
Bro can u suggest best supplement name of b12
@@josephinelai4638 Japanese doctors don’t allow their patients to go down below 500
@@padmeshsethuraman5617 Thanks .
@@RaghavVaikhansam23 I take Solgar sublingual 1,000mcg x 2 every week
Thank you doctor for sharing and all imporpmation
Thank you for this helpful video! I was low on B12 off and on mostly off. Been on it idk for one year consistent and prior a little. My recent bloodwork showed high but now I want to discuss this info with my neurologist perhaps we may still need to increase it. And I’ll mention this to my cardiologist/and neurologist for the brain. I had a stroke on New Year’s Eve 2023 at 56 I was taken aback by this. I may actually need more B12 as I suffer now from neuropathy of the feet. Thanks again for this helpful video!
that was so informative! well explained! thankyou!
Thank you Dr. Very informative.
Glad it was helpful!
Thank you no wonder my neuropathy in my feet did not go away when I was given 50mcg tablets for it I also subscribed to your channel again thank you
This is helpful guidance. I suffer from CFS - poor muscle control. I used to take B.12 in a small does with other vitamins. Recently updated this to 500 mcg and I must say there is an improvement in my muscle tone. thank you.
Thanks for good sdvise
Thank you so much for your helpful video to clarify my long time questions regarding supplementation of B12. Should B12 be taken alone or should it be taken with folate to make it effective?
I take B-12 with Folate and p5p, its a formula by Jarrow, i purchase it at Whole Foods!
@@healthyone100 hi’ could you please tell me what is P5P ? And how it helps with B 12. Thanks in advance much appreciated.🙏❤️
Hi P5P is the highest quality B-6 you can buy regular B-6 is junk, P5P is the natural form the other is synenthic!
@@healthyone100 Thanks.
@@healthyone100 thank you so very much. I appreciate you big time…! I am learning with these Vitamins.👍😊🙏
More than an excellent video, thank you so very much! ❤😊
Please Keep Sharing Spreading Love Truth Discernments And Good Common Sense.
Proverbs 3:5-6
John 14:1-26
Psalms 91
🕊❤️🙏🏻🎉
thanks FOR ADVISE
Wondering about too much of something and would appreciate your thoughts. As a diabetic I've experienced diabetic neuropathy for the past 5 years with numbness to mid calf. Most recently I'm expiencing significant difficulties in walking and am pretty much constantly tired. Past month I've been using benfotiamine without any benefits, but noticed on a couple of occasions that my condition worsens if I eat more than 6 slices of bread in the day. Does the bread react in any way such as interference with vitamins B?
Hi Michael. Yes, the bread (and all complex carbohydrates known as starches) will cause your glucose levels to shoot up. It will be extremely difficult for the Benfotiamine to stay ahead of the game. You need to adopt a ketogenic diet with intermittnet fasting. This is key. You will also need more than just benfotiamine. You will need ALL of the vital nutrients for nerve repair. I'm including 2 links to my video that you definitely need to watch:
th-cam.com/video/wPruq49-ksU/w-d-xo.html
th-cam.com/video/dKMPMPJM4JY/w-d-xo.html
Also, watch these 2 videos on reversing diabetic peripheral neuropathy:
Part1: th-cam.com/video/ks-WJD3WOjs/w-d-xo.html
Part2: th-cam.com/video/pnOIvXW9Qyw/w-d-xo.html
This will put you on the right track.
In the United States bread equals potassium bromate and Roundup. It will destroy your thyroid and gut.
Started to develop a lump under my foot. B12 has eliminated it. Numbness reduces tingling gone. Am taking B12 for the rest of my life
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
Many thanks, Doc. You delete my afraid of being toxic by b12
You are always very welcome, Pramuji. Blessings to you.
@@NerveDoctors I just upped my 5000 McG to 10,000 McG due to this video. Almost a full body neuopathy caused by levofloxacin. I'm the one you've been corresponding with , Christopher Kording. I'm loosing hope honestly though, very depressing disorder.
Never lose hope. I will pray for you.
@@johnnyappleseed5029 thanks
@@junechris ፡፡፡
@The Nerve Doctors As someone else commented , my labs showed above normal B12, I felt fine. She asked me to go off it to make sure wasn’t symptom of something serious like cancer . Levels went down to normal range. But now I’m having muscle joint nerve pain again , so taking more but was scared because worried labs would be too high. If we excrete excess, what is causing high lab levels and is this a concern . Could it just be normal for me to be high , are labs truly good measure . Thanks so much!
watch video again. no danger in high b12 .
I recently read that low Vit B12 can read as high on tests. Don’t take my word on it, though, might be worth looking into.
If you're worried, do the methylmalonic acid test to know your B12 levels instead B12 serum test
Fasting can help with many nerve issues. Some benefits of doing occasional extended fasting: High blood pressure is lowered to normal levels very quickly while fasting.
Fasting restores NAD+ to healthy levels.
Vitamin D plasma levels are increased as fasting improves metabolic health, and vitamin D in turn increases autophagy.
Fasting stimulates phagocytosis, the ingestion of bacteria, plaques and viruses by the immune system. It will also remove any 'foreign material' like spikes that are not supposed to be there. Whether natural or unnatural in origin..
Fasting increases nitric oxide release.
Telomeres are lengthened and fasting also increases anti-aging Yamanaka factors.
Blood clotting is reduced and blood clots and arterial plaque are reabsorbed into the body.
Reflexes and short term memory are increased.
Fasts from 36-96 h increase metabolic rate due to norepinephrine release!
After 72 hours or more fasted, your body recycles up to 1/3 of all immune bodies, rejuvenating your entire immune system. This helps prevent the onset of new autoimmune conditions, which develop through a leaky gut and damaged immune system.
Fasting can help with MS, Depression, BPD, Autism and seizures.
Thymus is regenerated, which suppresses aging and renews the immune system. The thymus also plays a vital role in fighting cancer.
Blood sugar and insulin are lowered when fasting, allowing white blood cells to move more freely throughout the body and do their job.
Weight loss from daily caloric restriction has 1/4 to 1/3 of the weight lost as lean tissue while many studies show fat loss from 36 h fasts without losing any lean tissue!
The obese will lose extra tissue like loose skin while fasting, but the skinny or frail will have increased growth hormone release than the obese, which helps to make more lean tissue and reduce frailness.
The hunger hormone ghrelin also lowers with extended fasting and rises from dieting.
When you move out of MTOR your body shuts down the building blocks of the cell required for viruses to replicate.
What breaks a fast? Anything with protein or carbohydrates in it will break a fast. Most teas and herbs are OK. Most supplements and meds will either break ketosis directly or contain a filler that will. Many meds are dangerous to take while fasting.
Does fasting lower testosterone? No, it raises it when the fast is broken by increasing lutenizing hormone. Fasting also increases insulin sensitivity, which helps with muscle building.
Fasts of 36-96 will not affect short term female fertility or affect menstrual cycle. They also may increase long term fertility, especially in women with PCOS.
Fasting reduces pain and anxiety by stimulating the endocannabinoid system in a similar way to CBD oil.
Fasting very quickly reduces leptin resistance, which impairs immune function. One day of fasting can cut your leptin levels in half and gets your immune system working properly again!
Stomach acid is reduced over time while fasting and can allow for the healing of treatment resistant ulcers. Some patients may need continued acid reduction medication while fasting.
Does the body preferentially prefer glucose as a fuel? No. Except for brief periods of very intense exercise, your body mainly burns fats in the form of free fatty acids. Your brain also prefers to burn ketones at a rate of around 2.5 to 1 when they are available in equal quantity to glucose.
Fasting stimulates the AMPK complex and activates autophagy.
Lowering insulin via fasting virtually eliminates chronic inflammation in the body.
It increases mitochondrial function and repairs mitichondrial DNA, leading to improved ATP production and oxygen efficiency. Increased mitochondrial function also has the added benefit of increasing your metabolism, fighting infection and cancer prevention!
Fasting releases BDNF and NGF in the blood which stimulates new nerve and brain cell growth. This can help a great deal with diseases like MS, peripheral neuropathy and Alzheimers.
When not in ketosis, the brain can only burn carbohydrate, which produces a great deal of damaging ROS the brain has to deal with.
Fasting also increases telomere length, negating some of the effects of aging at a cellular level.
When you fast, this stimulates apoptosis in senescent or genetically damaged cells, destroying them. Senescent cells are responsible for many of the effects of aging and are a root cause of the development of cancer.
A fasting mimicking diet for 3-5 days in a row also provides many of the same benefits as water fasting. FMD usually has 200-800 calories, under 18 g of protein and extremely low carbs.
Exogenous ketones can aid with fasting, making it easier in healthy people and allowing some people with specific issues to fast in spite of them without worrying as much about hypoglycemia.
Children, pregnant or nursing women should not fast for periods longer than 16 hours. People with pancreatic tumors or certain forms of hypoglycemia generally cannot fast at all. Type 1 diabetics can also fast but it is more complicated and should be approached with caution as it could lead to ketoacidosis. If you experience extreme symptoms of some kind, especially dizziness or tremors, then simply break the fast and seek advice.
Resources:
www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6141719/
www.ncbi.nlm.nih.gov/pmc/articles/PMC7607739/
www.ncbi.nlm.nih.gov/pmc/articles/PMC3017674/
pubmed.ncbi.nlm.nih.gov/23408502/
www.amjmedsci.org/article/S0002-9629%2815%2900027-0/fulltext
europepmc.org/article/MED/22402737?javascript_support=no
onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2265.2005.02288.x
www.nejm.org/doi/full/10.1056/NEJMoa012908
www.collective-evolution.com/2017/05/16/study-shows-how-fasting-for-3-days-can-regenerate-your-entire-immune-system/
www.arcjournals.org/pdfs/ijrsb/v3-i11/7.pdf
n.neurology.org/content/88/16_Supplement/P3.090
www.ncbi.nlm.nih.gov/pmc/articles/PMC7093158/
clinical.diabetesjournals.org/content/36/3/217
pubmed.ncbi.nlm.nih.gov/20921964/
www.sciencedirect.com/science/article/pii/S0005272806000223
pubmed.ncbi.nlm.nih.gov/6859089/
www.ncbi.nlm.nih.gov/pmc/articles/PMC8470960/
www.clinicaltrials.gov/ct2/show/NCT04375657
www.cell.com/cell-metabolism/abstract/S1550-4131(15)00224-7
repository.upenn.edu/cgi/viewcontent.cgi?article=1537&context=edissertations
www.ncbi.nlm.nih.gov/pmc/articles/PMC1779438/
pubmed.ncbi.nlm.nih.gov/2518860/
pubmed.ncbi.nlm.nih.gov/29727683/
www.nia.nih.gov/news/research-intermittent-fasting-shows-health-benefits
medicalxpress.com/news/2022-10-treatment-pulmonary-fibrosis-focus-telomeres.html
www.ncbi.nlm.nih.gov/pubmed/10859646
pubmed.ncbi.nlm.nih.gov/25909219/
www.cell.com/molecular-cell/fulltext/S1097-2765(18)30605-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276518306051%3Fshowall%3Dtrue
pubmed.ncbi.nlm.nih.gov/28235195/
www.ncbi.nlm.nih.gov/pmc/articles/PMC2815756/
pubmed.ncbi.nlm.nih.gov/7714088/
pubmed.ncbi.nlm.nih.gov/31890243/
pubmed.ncbi.nlm.nih.gov/15522942/
faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.2019.33.1_supplement.819.10
www.biorxiv.org/node/93305.full
www.ncbi.nlm.nih.gov/pmc/articles/PMC5895342/
www.ncbi.nlm.nih.gov/pmc/articles/PMC6526871/
www.health.harvard.edu/heart-health/abundance-of-fructose-not-good-for-the-liver-heart
www.ncbi.nlm.nih.gov/pubmed/25686106
pubmed.ncbi.nlm.nih.gov/21410865/
www.ncbi.nlm.nih.gov/gene/25712
pubmed.ncbi.nlm.nih.gov/23707514/
www.ncbi.nlm.nih.gov/pubmed/24905167
pubmed.ncbi.nlm.nih.gov/31877297/
www.cell.com/cell/fulltext/S0092-8674(19)30849-9
pubmed.ncbi.nlm.nih.gov/27569118/
www.ncbi.nlm.nih.gov/pubmed/10232622
academic.oup.com/ajcn/article/81/1/69/4607679
www.sciencedirect.com/science/article/pii/S1931312809002832
www.ncbi.nlm.nih.gov/pmc/articles/PMC1413655/
www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/
www.ncbi.nlm.nih.gov/pubmed/23876457
www.ncbi.nlm.nih.gov/pmc/articles/PMC6407435/
www.nejm.org/doi/full/10.1056/NEJMc2001176
pubmed.ncbi.nlm.nih.gov/20102774/
This list compiled over years of research by the user known as Pottenger's Human on youtube but feel free to copy and paste this anywhere you like, no accreditation needed!
My channel will always contain an updated version of this list of fasting benefits on the community tab. I also have playlists on fasting and health topics.
@@LTPottengerhow exactly?
Thanks
Your work is excellent, but can you say the optimum blood levels for a person with neuropathy ?
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got lunge cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
thanks for the post---very informative...
I managed to get B vitamin poisonoing from drinking 1 - 2 cans of RedBull for half a year because it helped me when I had extremely low hemoglobin in the blood. It took 4 months of no more energy drinks before I started to feel normal again, it was absolutely horrible feeling sick and nauseous with only a few hours a sleep every night for months. But doctors say my kidneys have reduced function.
The B12 in energy drinks is the artificial B12. Cyanocomalamin. That's the one everyone should avoid
Synthetic b12 and high sugar or artificial sweetner garbage ingredients
12/2024.
Most websites say that Red Bull contains under 2 micrograms of B12.
5 Hour Energy starts at 500 mcg.
I don't think Red Bull did anything but give you sugar and Caffeine..
Read Red Bull label.
The big 20 oz. can has 200% of RDA. Not much B12, there.
Thankyou this realy helps .
I dont know. Cruising YT there is an absolute cesspool of conflicting info on B12. Its infuriating.
This doctor says its safe whatever dose you take. The problem is what do you do when b12 makes you sleepy and lethargic ? There are even health -care amateurs claiming that cobolamin can build to toxic levels if the b12 uptake is incomplete due to low stomach HCI and Intrinsic factor. Therefore - Toxic (can cause anxiety and lethargy all day long)
The sleepy and lethargic reaction is very common. There are tons of threads on Reddit about it.
So. ITS NOT SAFE ! It does matter how,when and how much you take . Just keep it in mind.
B-12 never discussed by doctors when I take metformin . I had to find outyself now my legs don't hurt at night.
The daily amount needed for a healthy adult is 2.4 mcg. My sublingual B12 is 500 mcg. I'm 76 and far from healthy, but my last blood test showed a 900 reading. A doctor friend described it as Wow. I have invested in a pill cutter. !
There was a semi recent study that linked high levels of B6 and B12 supplementation to a 3-4X risk of lung cancer. How does that play into all of this?
Not well. In fact there are multiple studies finding increased risk of lung cancer associated with B12 but none showing causation as yet. Not hard to find these with a bit of googling. Some of these studies are with very large number of subjects too. Probably best to compare the typically high doses in these studies with what one’s doctor might be recommending and weigh up risk/benefit after discussing with the doctor.
Dont listen to this doctor. He has no clue about side effects from overdosing. Just type in B12 SUPPLEMENTATION CANCER. There are studies for example released in oxford acedamic (including 300.000 people). My father got lunge cancer from long term too high b12 supplemention (1000mcg) and died may 2024. I know 3 further people who got cancer from B12 supplementation. Everyone of them 4 took folic acid (too high dose increased cancer cells as well), B12 and pantoprazole (Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion, it also reduces the absorption of vitamin B12 (cyanocobalamin) and folic acid due to hypo- or achlorhydria which causes b12 and folic acid deficiz long term. So you have to take tablets but in low doses. B12 for example, everything over 25 mcg long term increases cancer chance by a landslide. ) And guys i dont underestimate B12. My father got dementia from long term b12 deficit before he got cancer due to b12 supplementation. Both means death. Just stay in the normal b12 level range (do blood test) without taking too high doses (more than 25 mcg is too high, except youre in a huge deficit, than you should take more but short term. Maximum 300 mcg in the morning and 300 mcg in the evening for maximum 2 or 3 months and only if you have a huge deficit. Also the human body only can absorb a certain amount of b12 per meal)..... The daily dose a healthy (b12 normal level) human body needs is 4 mcg per day and you get that without pills when you eat animal products. b12 is only in animal products e.g. eggs, milk
3 times Doctors have told me to take B12. 3 time after a week of taking it I got light headed so bad I thought I'd pass out so I quit. This latest episode had me in the ER were they said I had irregular heart beat....How can you say there are no side effects? I was taking 1000 MCG tabs once a day of Cyanocobalamin. Is the other one that beings with an M...forgot what it is......but it one better than the other. I'm done with B12. Also is it bad with other meds....I also take Lisinopryll and hydrcloroziodie Thanks
Toxicity induced by multiple high doses of vitamin B12 during pernicious anemia treatment: a case report
Context: The clinical consequences of excess vitamin B12 induced by multiple oral doses of cyanocobalamin are not well-known. Case details: A young woman was treated with multiple daily doses of 1 mg of cyanocobalamin for severe pernicious anemia. After a total dose of 12 mg, she developed acne, palpitations, anxiety, akathisia, facial ruddiness, headache, and insomnia. She improved two weeks after stopping the drug. There were no sequelae nor complications. Discussion: Although these symptoms of cobalamin toxicity were unexpected and unusual, the case reminds us that the administration of any drug is not entirely safe.
Avoid cyano form. Try methyl B12
Are Methylcobalamine the one you’re thinking about? I would check your B1 levels if I were you. Those can be the symptoms of wet beriberi. If you suddenly increase one vitamin or mineral the demand can increase for others as well. If you’re on the edge of a B1 deficiency supplementing with a large dose of another vitamin can push you over the edge. Ask your doctor for a 'Whole blood thiamine testing' and not a serum or plasma.
How long after the B B date can you take Vitamin D3 / Vitamin C - & - how long after Exp. date can you take the vitamins
@ 6:28. 1500mcg to 3000mcg
Hi l have underactive thyroid how much B12 would l have to take
After 2 doses of Methylcobalamin B12 injections (2 weeks apart), my B12 level went from low-medium (320 pmol/L) to absolutely way to high (1132 pmol/L) normal range is 200-600 pml/L in Canada. This blood test reading was 8 days after my 2nd injection.
Question: How long will it take for my body to get back to a normal B12 range. Praying this hasn't damaged me permanently.
I had a headache and strange anxiety systems, followed by total insomnia.
If you take injections for pernicious anemia or B12 absorption issues, your B12 levels will be >1,500 if you inject monthly. But don't worry those numbers really don't mean much. You're not using all that B12. Most of it is getting eliminated through urine. It takes months for it to go back down, And by that time you'll be do another injection, so don't worry those numbers are not going to affect you. Doctors shouldn't even be testing your B12 if you're on injections. If you have a B12 deficiency and you have to inject B12 monthly, weekly, daily, whatever it is, it's going to raise your B12 levels for the rest of your life. You really can't go by those numbers anymore once you start injecting B12. They become obsolete.
Methylcobalamine is the pure form of B12. Our bodies convert B12 into methylcobalamine. Cyanocobalamine and hydroxycobalamine need to be converted in our bodies. Which is the natural process. Some people can't tolerate methylcobalamine. I use hydroxycobalamine or cyanocobalamine because it's readily available in ampule forms, where methylcobalamine is only available in powder form and has to be mixed with injectable saline. Methocobolamine can cause insomnia, can make you break out with acne, and can give you quite the headache and anxiety. But that is the worst of the symptoms and the worst that can happen to you. Cyanocobalamine and hydroxycopolamine usually don't cause those side effects. One time I bought the powder for methylcobalamin, and my pharmacist miscalculated the dosage so over 5 days, i injected enough for 30 days. I had terrible insomnia and a terrible headache but after it started to wear off a little, I had no pain in my feet, my body felt fantastic for the first time in a very long time. That was a mega dose of methylcobalamine. The methylcobalamine is an excellent B12, but some people can't tolerate it. And you can't get it in single dose ampules, or I would be using that everyday! multi dose vials are susceptible to contamination. I think once you get used to methyl cobalamine, the insomnia and headache etc will get better.
If your body was starving for B12 for a very long time, and you start injections, you get what's called reversing out symptoms. That's where your body starts reversing out all of the symptoms your body was going through from not having B12. When I first started injecting B12, I hadn't had B12 in my system for probably more than 25 years. So when I first started injecting my liver really started to hurt and my stomach started to hurt and all of my body was very sore. The neuropathy got so bad I was crawling to get around, not to mention the brain fog, the inability to find my words and form a sentence, I was in pretty bad shape. But then it started to get better. So if you've got pernicious anemia or B12 deficiency absorption problems, And you've had a deficiency for a long period of time, these symptoms can get quite painful. So when you start taking B12 and it starts to reverse those symptoms and starts to heal them your body will go through some painful changes. But it does get better and it starts to even out. I still suffer terribly though from neuropathy and weakness in my legs because I have macrocytic anemia. And so far I haven't been able to get that to get any better. I'd say I'm about 40% better in general than I was last year, and that might be as good as I'm going to get.
So yes methylcobalamine can cause headache, insomnia, acne and anxiety, because it is the purest form of B12. And some people can't tolerate it. But it is the best form as far as helping symptoms goes in my opinion. It's just not readily available for self-injecting. The next best form is hydroxycopolamine, that's what they use in the UK, and cyanocobalamine which is what we use in the United States.
@@18eleanor They said TO AVOID, and NEVER take Cyanocobalamine, as it is the bad form of B12 as it has Cyanide in it. They only suggest the other forms especially Methylcobalamine. Thank you for sharing your experience, I learned a lot from it, Thank you, Blessings!
I just want to reiterate here that you cannot OD on B12! If you have to inject B12 your B12 levels will always be >1500. That number is completely obsolete and means absolutely nothing and the fact that any doctor is testing a patient's B12 after an injection is an idiot. They should know that you cannot test B12 after injections because the numbers will be through the roof. And they will be for the rest of your life and never never never never never accept your doctor saying you don't need any more B12 if you have pernicious anemia if your numbers are greater than 1500. You need B12 for the rest of your life daily weekly monthly whatever it is that you need it, you need it for the rest of your life and your numbers will be greater than $1,500 forever. That number is obsolete it means absolutely nothing. You're not using all that B12 your body will eliminate it and pee it out. It does not affect you in any negative way whatsoever. Do not wait for your numbers to go down before you have more B12 if you have pernicious anemia or B12 deficiency that needs injections. If you have to have injections you have to have them for the rest of your life. Unless you're a vegan or vegetarian whose doctor just wants to get you quickly up to a good level they might inject you for a couple of months and then they will go back down and tell you to take sublingual B12. But people with pernicious anemia not caused by a diet, need B12 every single month if not every day for the rest of your life. Do not listen to any doctor who says your B12 levels are too high because you've been injecting B12 that doctor doesn't know what he's talking about. And he needs to go back to school. Those are the doctors that are ruining everything. Doctors have about 15 minutes worth of schooling and medical training on supplements and nutrition. They know little to nothing about pernicious anemia treatment and B12 deficiency. Everything I'm telling you I have had to learn through the pernicious anemia society. They're the ones who know what they're talking about they are the pernicious anemia society they know what pernicious anemia is how to treat it and what the truth is. Please visit the pernicious anemia society.org for the truth about vitamin B12 deficiency pernicious anemia. It is imperative that you do not listen to a doctor who tells you your B12 levels are greater than 1500 after he injects you with B12. Stupid doctor
Any side effects you had from the B12 injections are normal It's because your body was starving for B12. It's like putting your foot in a clear lake and touching the bottom and having all the mud and muck start swirling around that's kind of what's happening in your body Your body has been broken and depleted of oxygen red blood cells and B12 so as you start pumping that back in your body's almost like a balloon feeling back up and all the wrinkles are coming out. And then once you get to that point where you're stable and everything is back to normal your body will start working better. But until it gets fixed it's going to go through a slightly rough period of time trying to repair itself. That's all your body is doing is getting used to having B12 that it has been depleted of for decades. It's just rejuvenating itself and it's trying to fix itself. That comes with side effects. Insomnia anxiety a headache. And things can get slightly worse before they get better. But that's just called reversing out and it is simply your body coming back to life. That is all it is. If you don't believe me please visit the health unlocked forum and ask them all the questions you want or go to the pernicious anemia society.org please Google those things and please ignore the doctor that says your B12 is too high after an injection. You need a new doctor. This doctor does not know what he's talking about. There is nothing to be afraid of with B12. It is a water soluble vital Ammon that your body needs. Whatever excess B12 isn't used by your body it will be eliminated through your pee. You will feel better soon. And the fact that you feel so badly I don't think one injection is enough for you a month. You sound like you may be somebody who needs at least weekly injections. But you're not going to talk your doctor into doing that for you. Very seldom can you get a doctor to understand that you need B12 more than once a month.
That reference range you stated Jim is for healthy people, if you have a deficiency you're not healthy, it needs to be a lot higher for you to feel well .
What's B12 supplements derived from?
And... is small fiber neuropathy a different monster than large fiber neuropathy; or do they go pretty much go hand-in-hand? Small fiber neuropathy (sensory nerves) in the hands and feet seems to be reported about as if it's a more frustrating to treat than large fiber; unless I'm missing something.
I copied your last message from yesterday and have added this to it. I immediately went over it with Dr. Coppola, who also agreed it was a brilliant topic for us to cover, so we've bumped another topic that we had scheduled for June and will be replacing it with this one. We should release this video on this topic by the end of June. Thanks so much for your suggestion!
I so appreciate your information!!
Akasha Joti You are so very welcome!
Agreed that we need more than RDA, but ODA numbers vary wildly depending on which source you use...
It is incredibly hard to determine ODA as it is so dependent on individual factors, and the state of the research is constantly changing... I recommend taking ODA numbers with a large grain of salt.
In my humble opinion, it would be better to simply try and get as much as you can of all essential nutrients while still staying below the NOAEL ( No Observed Adverse Effect Level), unless treating a specific condition under the supervision of a physician.
It may still be necessary to further limit your intake if you have a sensitivity or allergy to the nutrient in question and must limit your intake further, or are taking medications that may be effected by high doses of said nutrient.
That said, cobalamin (B12) is INCREADIBLY safe... So much so that there is still no firmly agreed upon NOAEL for it, with the Scientific Committee on Food stating “…there are no clearly defined adverse effects produced by vitamin B12 that can be used to define a LOAEL or NOAEL, which can be used as a basis for deriving an UL” .
However I am aware of two recommended NOAELs based on the synthetic form cyanocobalamin based on rat studies, with suggested NOAELs of 100mg/kg/day and 500mg/kg/day respectively...
yes that is mg, not mcg!!
and the natural form Methylcobalamin is considered even safer....
However, this does not mean that you may not have an individual sensitivity or allergy to B12 that may lead to skin rashes, GI upset, or even anaphylaxis, even at much lower doses...
So like everything, while this is a VERY safe vitamin for most people, don't start mega dosing blindly, work your way up to higher doses slowly, and even then just in case, it is probably best to keep your daily intake under 2000-3000mcg/day unless under the supervision of a physician.
Nice one Michael, caution is always needed, just look at some of the comments here like Jim Doukis and Connie Waterman, it just goes to show that there is no one size fits all answer.
Sound advice
Thank you for your teaching to me who’s have no idea how much more I can take.
Being a vegetarian I bought Solgar B complex with 2mg of B12. That was listed as 83,000% of RDA in one ML eyedropper. I did one once per week. At that week or the next I began to have TOTAL insomnia! Checking the web confirmed it could. I stopped and soon I was sleeping normally. I also read that the liver stores it a long time so likely can accumulate. 😮 I guess it could have been some of the B complex too.
Did you take it right before bed? If the supplement contained the B12 form Methylcobalamine it’s no wonder you got insomnia if you took it before bed or late in the evening. Most people will get a bit hyper and agitated on Methylcobalamine.
solgar is my favorite brand. I take b12 in the morning rather than at night.
Before listening to this video, I listened to the TH-cam video called, "Is too much B12 bad." (Can you take too much B12.) He says the opposite of Dr. Coppola. He says that it is very possibly linked to lung cancer and other cancers. What do you think of the Trainers cancer view?
sounds like your doc is fishing for someone to prescribe expensive cancer drugs to...
So the optimal daily allowance for general good health is 10,000 mcg daily - but if you need nerve repair, then you need at most 3,000 mcg daily? Does this make sense to you? It’s hard to imagine a more confusing video.
I think you missed the point, he was just comparing the RDA and the ODA which is what they say you should take . Remember he said everyone is different so the 1500-3000 mcg is the overall recommended daily amount for everyone . So if you drink or smoke or have something else going on you might need more , just like the case he was talking about where they gave the patient 60.000mcg daily.
With oil-soluble vitamins, there is always a risk to the liver if you take too much. D,E,A,K are the vitamins you must be careful not to take in excess, unless under the care of a professional.
Excesses of water-soluble vitamins are easily dispose of through the kidneys. For those, it becomes more a cost/benefit analysis of throwing away excess vitamins.
Thank you that gave me peace of mind
I have had peripheral neuropathy in my feet for about 3 years. I currently take 500 mcg. Vegan Methylcobalamin in an organic spray once a day. I usually take 2 sprays. Should I take maybe 3 or 4 sprays instead and should it be sprayed under the tongue?
Thank you!
Thank you so much Doc!
After seeing the recommended 10,000 mcg to be optimal I have a question, (I’ve been on B12 for a few years (was deficient at one point due to vegetarian diet for about 8 months) and noticed my levels are continually above the “lab range”. Most of the time 1200-1400. I will remove the supplement (2500 mcg daily) to lower it, but then I start to have deficiency symptoms. Is having above the normal serum levels ok if I feel I need it? And do some humans just need more?
Hi B4L. I just filmed a whole video on this. Watch this weeks video. It will be released on either Thursday or Friday of this week on B12 deficiencies. It completely explain why your lab values read normal while you show signs of deficiency. Blessings.
@@NerveDoctors I can't find this video. I'm the same, my b12 has been over the lab range and now i'm getting peripheral neuropathy and I have POTS.
avoid coffee it drives B vitamins out of your body very aggressively
Which food is good for neuropathy.
Shittake mushrooms work for me. They're high in choline.
When I had my stroke they told me all my labs were good except that I had almost NO B12 in my system. I asked him (the neurologist) what would cause that ?? He really didn't answer me except to say take it every day. You will just pee out what you don't need.
If you are not vegan then you need b12 injections with low level . Taking b12 supplements will not help due to malabsorption issues
Take folic acid with the injections to heal at cell levels and multi b vitamins heals cognitive decline