Solving the HSP Puzzle

MNI scientists have identified novel gene mutations that cause hereditary spastic paraplegia (HSP), a step forward in efforts to treat this debilitating disease. Learn more here: www.mcgill.ca/neuro/HSP-gene-m...
Des chercheurs de l’Institut et hôpital neurologiques de Montréal (INM) ont identifié de nouvelles mutations génétiques qui causent une forme de paraplégie spastique familiale (PSF), une étape de plus dans les efforts visant à traiter cette maladie invalidante. Pour en savoir plus: www.mcgill.ca/neuro/fr/paraple...

[@jeffwooten]

I have this disease. Some doctors around me in southern Missouri and some don't know anything about it. Thank you for the information

[@rashidt7808]

Sir if you found any solution. I humbly request you that Please open talk to world. Have HSP

[@floor1077]

Me to! I have the feeling i cant live so long like this

[@MsMOLLYKINS]

I have lupus predominant health issues and last yr told I have hsp. No one warns you or explains anything , my neurologist through his hands in the air and said there's nothing left to do. I am becoming wheelchair bound my legs feel like cement . I go to take a step and my feet feel like their stuck. I am about to start self catheterisation because I struggle to urinate and I really can't feel when I begin and end . I always feel like pressure down in that region but never busting to go. Anyway hope the research gives up more information we need it thanks from Sydney Australia

[@mohammedkaleem2794]

Great Doctor.. I wish you good luck and be blessed in your research

[@rashidt7808]

Assalamu alaikum

[@Monkofmagnesia]

I have what was called spastic diplegia, than idiopathic spastic diplegia, and, finally, just a couple of weeks ago, spastic paraplegia (after having my one and only genetic testing. I have been going to doctors since 1973). I have the Baclofen Pump, use a cane in each hand and a walker. I used to be able to run and even dance on stage (I had been inolved in community theatre since 1980). Now I have two leg braces as well. Every time I seem to be getting the walk back (via physical therapy) it becomes twice as worse as before. No one on either side of my family, living or dead has this. I no longer know where to go for answers.

[@il3mendo]

Doc I have have spg4.
May I ask you how spastin and ketanin interacts with the atp ?

[@vt68]

I'm very glad to see that there is progress being made. Where can I go to get more information on your work?

[@MontrealNeuro]

Hi. Sorry for the late replay we just saw this. You can learn more about the study here: www.mcgill.ca/neuro/HSP-gene-mutations

[@concrete3030]

Any updates?

[@TheArtisticCat]

Will leg braces help with my walking?

[@peterscarfe4354]

My Dr Tells me that HSP does not worsen over time,but 15 years ago i could walk without a stick and now i cant balance or walk far i have to fall on to the walls in the house and i stopped leaving the house 10 years ago.im sure he is wrong as my condition is worsening.Is he right or Wrong about this ?

[@sourabhgoyal553]

Your doc is wrong situation worsens bcz I'm not able to walk I have same disease but atoq to my doc baclofen pump can be good option

[@SuperHigear]

Keep up the great work, Doc, we want to walk again...

[@ronnielott73]

YES WE DO!!! THANK YOU SO VERY MUCH!!

[@rashidt7808]

Currect we will walk normally

[@swapnilhelkar769]

@@rashidt7808 hello please share ur contact details...
I hv also hsp

[@tiktoksgoneviraltiktoksgon8731]

I had hsp at age 10 it went no I'm 11 it came back I also had a weell chair it's really painful I struggle to work

[@juliedesmaraistrepanier8077]

wow!!

[@Trey_Alexander]

Guessing the research has just stopped?