Is THIS the NEXT BIG THING in Skincare?
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- เผยแพร่เมื่อ 28 ก.ย. 2024
- Looking at the science behind EGF to see if it's worth our money!
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I am sticking with Tretinoin, an antioxidant serum, and a moisturizer with peptides. At 73 I’m going to embrace my wrinkles as proving I’ve had a life well lived.
Me too … just turned 70 ,I’m beyond fine lines and I’m happy with the Tretinoin and all my serums .
Me too at 63 😊
Same. 66 here. Loving my skin and happy with it. Retinol, antioxidant serum, peptide moisturizer, sunscreen. Weekly AHA peel. That's it.
@@joycebenvenuti4782 Same at 59 I’ll stick with my retinaldehyde, Peptide night cream and my serums.
@@elizabethmyers1328what antioxidant do you use? & moisturizer w/ peptides thank you 😊
I tried both Skin Medica and Neocutis and they didn’t do a thing to improve my skin. Do not waste your hard earned money. I’m 58 and am constantly getting compliments. I use products from Neutrogena, Cosrx, the Ordinary, and Timeless. They do a better job to keep my skin balanced and healthy and they don’t break the bank!
Hi Angie I was a Registered Nurse for many years and won’t buy growth factors either. The possibility of proliferation of skin cancer cells in the human bioengineered stuff is a big no and plant based - well I am not a plant 😂.
I have rosacea and eczema so my skin barrier is chronically impaired therefore I use a lot of caution when choosing skin care. My rosacea hates retinoids during true menopause (I could use them carefully prior to becoming fully menopausal), but I believe in their efficacy as a topical treatment. My active of choice is azelaic acid- it has made the biggest difference in how my skin looks. Obviously I use spf and as I live in the UK use ultrasun or Evy with their more longwear modern filters (ultrasun is available on prescription for skin cancer patients btw). Niacinamide is nice, my skin absolutely hates vitamin C and peptides are hydrating😂. There is no miracle cure for aging and I personally am happy to have lived long enough to even worry about it. I was involved in cancer nursing for many of the years spent in that profession and trust me not everyone lives long enough to worry about aging/wrinkling. I want calm, hydrated and moisturised skin but just embrace the signs of aging as a life lived. My smile lines are far more prominent than frown lines so it is a reflection of that life on my face.
I am not however on camera on social media with all the pressure about how I look that entails, so no judgement etc. I do think procedures will have a far more obvious impact than anything topical, so for those buying 300$ serums saving that money towards a procedure may get you better results. Best wishes x
Have you tried over the counter butt paste for rosacea? Like desitine? Works!
Yes, here for the azelaic acid - makes huge difference to pigmentation (the only thing I really want to get rid of) - and niacinamide (my 66 y o skin was parched, nothing worked, until I discovered it, funnily enough in Cerave) Retinal works well, but so does a 1x week fruit enzyme peel. And why IS vitamin c so problematic - I sweat that was what wrecked my skin barrier and started off kp! Growth factors are such a half-understood science - def not going there.
@@halfamo2422- what tyoe of enzyme peel?
Agreed 100 %, past oncology nurse here too!
Totally agree about vit c! Rosacea is such a pain. I'll try the A acid you mention.
I used Neogenesis Recovery for over a year and saw no changes at all.
Thank you, it's so difficult to find opinions!
I was recommended that product over the skin medica TNS . Thank you for sharing your experience.
I’m sticking with the TNS for now . I’ve seen ppl who use it religiously and there skin looks younger than there age . Bc of its cost (with even its crummy pump dispenser) I just don’t spend money on other products, it covers all my skins needs -except for sunblock and retin a which I still Purchase , but both those are very affordable lol
@@Alykat736 - so you use Retin A and the other product?
Same thing for me with TNS. My dermatologist recommended it - I used it - didn’t see a difference.
I stopped using growth factors after using it for 5 years. The skin cancer experts are concerned that the skin growth factor’s will grow both the healthy and the cancerous cells.
Thank you for the scientific deep dive. You really did your homework. I'll stick to retinol, sun screen and peptides.
Me too!
What is a good peptide?
Frantically waving nerd flag - excellent job!! You basically did a PhD thesis literature review in this video! Scientific research isn’t perfect but you consistently provide excellent summaries of ALL the data, good and bad, with enough nuance for folks to make their own choices. Nuance is sorely lacking in media these days, and I deeply appreciate your work and contribution. I’m sure these videos don’t perform as well as others, but please don’t stop making them!!!
These are my favorite type of video that Angie makes.
Hi, Angie, you are starting to sound like a scientist, you really dug in deep! Thank you for all your hard work, I appreciate all you do for us! Have a great weekend!❤️
I didn't know if I'd find my way back from that rabbit hole!! lol 😆 It was fascinating!
@@AngieHotandFlashy 😂❤️
Her dad is a scientist ❤❤❤
Angie is her father's daughter for sure!! I love that.
Well, her Dad IS an actual Scientist, so, as they say, "little apples don't fall far from the trees!" Lol.
As others have requested, I am eagerly awaiting your in depth review of estrogen cream for your face (estriol or estradiol?).
That video will come out in December.
I hope you will address whether HRT might affect the efficacy of topical hormonal therapy…. Thanks for all you do Angie! Love your content.
Thank you. I am sure I am not alone in looking forward to this
@@AngieHotandFlashyhave you checked out dr Abs video of testosterone cream? For women too. He’s brought out compelling research and doing it himself, also he said oestrogen isn’t that great for anti aging compared to testosterone.
Yes !! I’m wondering if HRT is worth it at 61.
Blue is your color! It softens your blonde and makes your eyes pop. You look beautiful.
So glad or did this video, I did try the skinmedica advanced my skin felt smooth but when it
Ran out I used Kiel’s hyraulonic serum which also felt smooth for much less money, will not buy growth factor serums again. Thanks again for this video
Agree!! Angie looks especially beautiful today!
I'm guessing that Angie used blue or purple shampoo to soften her hair color. It really works!
She looks good in anything she wears!
$295 for one bottle?? When there’s people who can’t afford to buy food and are homeless, I would rather donate money to them than spend $295 on a single bottle of skincare.
I feel the same way!❤
I’m so happy other people feel that way too. I can’t imagine spending that to maybe look a little younger. At 65 I love the way I look. And like you I want to spend it on my grandbabies, or to a favorite charity. These prey on the people who want to look younger. Embrace your beautiful faces ladies and gents.
THANK YOU! Good grief!
1 oz, it is 1 oz for $295 plus taxes and fees.
300.00 bucks. Bs, ejal 40 is 30 bucks in uk. I use this to induce collagen. It works fantastic.
So basically growth factors don’t work and they are mainly just humectants? WOW so good to know. I’m going to start saving some $$ ❤
When are you covering the estrogen cream. I got my compounded Estriol cream about 9 days ago. Also putting on my hands and forearms. They are in rough sun damaged shape after 59 years.
I'm doing a 6-month trial on it (that's how long they say it takes to see a difference) so I'll do a video on it in early December.
@@AngieHotandFlashy perfect! I'm having a delayed midlife crisis getting so close to 60. I've got my large menopause tool kit, walking daily, trying to get enough protein, weighted vest+++🤣
Love the deep dives! Had same ? re the estrogen cream (using Alloy) and now wonder is it “small enough” to penetrate skin? Since it’s a hormone, don’t know if that works differently? Thank you!
Estriol is too weak to do anything. Estriol is the estrogen that is left after menopause because it is produced in body fat. What waste your time and money?
@elsagrace3893 fat cells make estrone. Estriol is made when you're pregnant . They actually have pub med articles comparing Estradiol and Estriol on skin and aging with similar results improving collagen and elastin. It's froma compoundingpharmacynot Amazon. Pharmaceuticalgrade.
Angie, Can you suggest or have a video on jowls and wrinkles around the chin area. I am trying so much and nothing seems to do it. Can you help. Please!!!!!!
Sorry hun, a face lift or just accept it. We all change. The beautiful young models that you are comparing your face with are also going to age and change just as you are.
Look into the Nua RF home device. Dr. Rajani recommends it, & this is the 1st time that he has Ever recommended Any RF at home device. And I trust him!
Go to how channel & watch his very recent video all about it
Check out the videos on using a Gua Sha tool or the channel Face Yoga Expert. It will really help to naturally tighten that area around the chin. You don’t have to just live with it and accept it as it is (as someone else said). ☺️
@@elsagrace3893That's rude. Why even comment if you do not have any suggestions?
@@meldavis2563Rude? She's just telling how it is, in reality. Also, she did have a suggestion..
Please make a video with solutions for back of hands thinning skin and veins. Thanks
Not sure there's a ton we can do about veins, but I've been having good results with estriol cream. I get mine through Alloy and ParlourGames. The one from Parlour Games has worked wonders on my hoo-ha, too. No more UTI's, itching or dryness 😁
Yes, please!!
Yes please!!!!
I know Angie uses red light “mitts” made by same company as her mask. Strivectin makes a hand volumizer cream that makes a noticeable difference to me when used consistently. They don’t really advertise it - not sure why.
Why not try micro needling?
Please do a deep dive into the ingredient "volufiline". Curious🤔
Yeah me too!!
I am an esthetician and I wish we had teachers like you at school. They knew nothing compared to you. Great video Angie! 💕
Thanks Angie! I have avoided growth factors. I am hearing a lot about DNA repair enzymes. Would you consider doing a video on this?
Absolutely!
I’m on my first bottle and also would love more info!
@@lynnecarr5791 I’m using DNA repair in my sunscreen (Isdin) and I’m loving it!
I just started the DNA repair enzymes as well. Wondering if it’s worth my money and time
Everything changing so rapidly with technology. I planned on a f/l around this time but hoping I don’t have to. I haven’t tried OmniLux mask/red light therapy yet. Hv been told tox will no longer mk my 11’s disappear bcuz they’re static. Might just try the Omnilux b4 I plan on surgery!!
You missed Calecim in your review for growth factors …
@@alonaburman5245
It sounds like you are also listening to Brianna😄. I just finished my Calecim and won’t be buying it again.
Thank you. I appreciate your critical eye when reviewing research.
Hello Angie, great video, your blue top suits you very well. May I suggest a deep dive into sculptra, radiesse, etc. if you have the time. Have a nice day.
Oh my goodness. While science advancements are very much appreciated, let’s face it, nothing will turn back the clock. Being and accepting your best self in every stage of life is the healthiest approach. The cosmetic industry is well aware of the “taboo” of aging in our society, especially for women, and they seek to financially capitalize on it. None of us are getting out of this life, “alive”. We are all going to age. Just do the tried and proven: limit sun exposure, wear sunscreen, use a retinoid or tretinoin, moisturize face and body, eat healthily, do both cardio and strength training min of 5 days per week. You are all set.
Amen to that!
I got convinced I needed Growth factors, so I purchased the Neocutis one...and nothing absolutely nothing changed.
Hi Angie! What are your thoughts on DNA recovery serums like Photozyme?
Yes i want deep review on those to. So many high end youtubers talk about them. But no one give us research and trial testing and delivery system.
I've been using "Bioeffect" Egf serum (a brand from Iceland, using a patented egf ingredient) for some years now during winter time. (live in Scandinavia with dry cold air) I haven't notice any revolutionary results in terms of younger skin more than from the tretinoin I use. I will say though, the capacity to keep moisture in skin and keep dryness at bay, then the Egf is outstanding. I can have the most dry flaky skin, and if I put it on at night, I wake up with soft, moisturized skin that arent dry anymore. And it only requires a tiny drop from the serum, it's potent in that way.
I totally agree - I love Bioeffect EGF Serum!
I'm not sure if TH-cam allows links in comments yet, but you might want to do a search on why there's controversy here. It isn't just neonatal foreskins, but in the cases of some companies, sometimes it's embryonic or fetal cell-sourced (resulting from an abortion in Switzerland, albeit one claimed to be "medically necessary", which is nevertheless murky ethical territory in a lot of cases. From some quick research, it appears that the original line of tissue came from a case where they had an unborn child being unlikely to survive, so the solution to that is (according to some)... to kill them. ***Whatever one's personal take on this, no one can claim this is uncontroversial.*** (And I don't care to hear from people who aren't bothered by it. I well aware these people exist and how they think.) Some buyers, then, would object to this or at least find it disturbing,, and would really want to know what they're buying. A quick search shows that Allure even has an article about the controversy, and I see stuff on Reddit as well. It's easy to find with the right search terms.
Thank you. Was wondering about that. Murky waters for sure.
Hi Angie. You are a scientific genius. I love all of your research and how well you delve into these studies.
I think I personally will skip the growth factors, and continue my experimentation with the vaginal estradiol used topically on my face in combination with the Tretinoin. So far, it's only been 3 weeks of using estradiol twice a week. I most likely need to bump it up.
By the way, for anyone interested, if you use a Good RX coupon for Tretinoin, for some reason the brand name, Retin-A is cheaper! It's also much creamier and therefore you need less than the generic.
Timeless Skincare is definitely the way to go for other products. I use all that you have recommended. I would never be without the Vitamin C, nor their Coq-10 serum.
You are the best!
Have a great weekend. Stay dry. We're finally getting much needed rain!❤🌧🌧🌂🌫
Same here, but I apply the estradiol cream about 5x/week, Tretinoin a couple days a week, and OneSkin daily.
I would love to know how your vaginal estradiol on the face works out. It's an interesting concept. I know several menopausal women using it vaginally, but no one using it on the face.
@kimberlyf4888 I'm going to up the estradiol dosage, but so far it's been fine in combination with the Tretinoin. A bit drying, but I always seal everything in with a moisturizer. 😊
@@kimberlyf4888 do you find the OneSkin to be worth it? I'm looking at the eye cream because that's where most of my wrinkles and fine lines are. I basically have a smooth face and very very fine lines. Biggest issue for my face and neck is sagging from 100+ lbs loss 3 yrs ago and surgery is the only way to fix that.
Be careful that you’re not taking too much estrogen if you use it both on your face and vag. Estradiol is much stronger than estriol
~THANK YOU ANGIE!~ I tried the TNS $280 gf serum a few years ago, took before and after pics and NOTHING! No improvement whatsoever, it was throwing hard earned money down the drain. I so appreciate your analysis of the statistics and data. It’s interesting how very small the study sample sizes are🤓🧐. As always excellent video!💕👏🏻🙏🏼🌷
So comprehensive! Was hoping you would do a video on this. I agree, the bottom line is if it could potentially make a skin cancer cell grow then it may not be worth it.
I saw a Huberman Lab podcast on skin and when the dermatologist said that, I knew I was out. I already had a stage 0 melanoma. Not taking that chance.
Considering this information , what is your opinion on topical estradiol/estrogen products . In my mind , the benefits and risks of growth hormone seem similar to estrogen products . I need more education . Is there a good review or expert of topical estrogen for beauty and health ?
She's testing this right now. Stay tuned!
Forget estriol. Estradiol is the only effective estrogen. We have plenty of estriol after menopause especially women who are packing extra pounds because it is produced in body fat. It has a very weak effect.
I can't use growth factors because I had skin cancer. 😢 But, thank you for such a great presentation of growth factors! I've never heard anyone explain it so well. Have a great weekend ❤~lori
Hey there! I’m over here flying my ‘nerd flag’! Thanks for the deep, deep dive into the research of these claims! I’ve been following you since just after you started your journey and have taken it ALL in to develop my skin care routine. At 72 years old now, it’s never too late to be our best selves! Thank you and thank you again for your efforts on our behalf. ❤️😘
Thanks so much Angie! I asked for this video from you months ago, so I appreciate all your research to help me understand this. My dermatologist told me not to use Growth Factors because I’ve had melanoma skin cancer in the past. I think this is important for people to understand.
Really informative and useful (and your hair looks great today!)
Thank you so much!
Inwould live to hear your thoughts about DNA repair products!
Fir now I agree I will stick with my usual!
Good morning Angie! Thank you for all the thorough research you do for us. I have been following you and have been using your skin regimen as closely as a I can for a few years. I get so many complements on my skin. I am in my early 60s. 😊Could you please review at some point the products from OneSkin and Adipeau ?
Hi Laurie! That's awesome to hear! I'll put them on the list! 💜
I've actually been using Adipeau for the last two years and a bit. While it may also do some nice things for the skin, it's primarily a fat cream. That is, it's designed to help with loss of facial fat. I don't think Angie has any significant fat loss at this point, so I don't think Adipeau would do anything for her.
Based only on my own experience, I think it does work to some extent. It didn't give me filler-type results, but it did restore some fat to the right hand side of my face. Benefits to the left hand side are less noticeable but extant. It's probably worth noting that my left side lost facial fat first. Adipeau also helps with the small hollows on the inside tops of my eyebrows. Alas, it did not help noticeably with my undereye hollows, but I've been happy enough with what it's done that I keep up a maintenance level. Also, it can take time that differs from person to person. For example, a You Tube journalist had some results with it within three months and not much more after that. It took six months for me to see anything (except lip plumping), but in the 7th month I got fast results for a bitand then incremental improvement for about another year. I'm now 72, by the way.
Hi Angie, once again you did a comprehensive research to save us some big money. Thank you!!!
You're so welcome!
Thank you for saving us a lot of money! 😊
10:20 so… Vaseline did the same thing😂😂😂
Yep!
LOVE the deep dives!!!!
Thank you for your research and honesty.
You just saved me tons of money .. I had used the TNS as well and was always questioning the results . We appreciate you so much !!❤
Hi Angie! Love your channel! Please try TIZO Primer/Sunscreen mineral tinted SPF 40 please. I know you tried another TIZO mineral sunscreen but the one I reference is AMAZING!!
I'm pretty sure I tried that one 7-8 years ago & it wasn't my cup of tea, but I'm so happy you love it! 💜
Love it too!
Love that blue color on you Angie.
i can't believe you just posted this video... i just asked myself this morning, "I wonder what Angie thinks of growth factors?". TY
thank you so much for talking about how cancer cells could replicate and divide! i will always have skin cancer on my face so i cant use the growth factors. I would not have known that if you had not said anything about it. Much love.
What a ripoff! I’m glad that I haven’t been tempted enough to buy those uber expensive face creams. 😅 Lots of manufacturers making easy money on this “anti-aging” industry. Good video!
Hey Angie TH-cam finally gave me a notice that you uploaded and that's been a very long time
Oh yay! I don't know what they're doing lately... YT never shows me my favorite creators any more & I have to go looking for them 😖😩
Same! I'm so disappointed that I don't get notifications anymore!
Thank you for taking the time to research this.
You know I'm a little skeptical about growth factors as well however, I will say that I've used two brands that are not the ones that you mentioned on the occasions when I micro needle, which is really only that once a month. I do have to say that the next day after micro needling and using the growth factor I feel like I wake up with great skin the next day and it does last for a while. I'm kind of a fan although these studies definitely give me pause.
I know that these do not absorb into your skin but, I just received some Frownies. Oh wow! Immediate results. Love them!
I am trying Calecim PTT-6 professional serum, almost done with vile #2 and just ordered #3. I am noticing the elasticity and overall plumpness of my skin especially my neck skin is better (not like in my 30’s or anything but it is improved) and my overall skin texture is improving, which was what I was hoping for. I blend three drops of the serum with Vichy Mineral 89 for better slip AM & PM. I have large pores due to sun damage and am post menopausal 56yr old using transdermal HRT. I have been using retin-a for 6yrs thanks to you, and vitamin-c serum as well. This brand is also approved for use with micro needling (I did a series of 4 treatments 3yrs ago and it works well for me with collagen stimulation and pores) so just had one of four in office MN treatment and used this after and my healing time was faster and I was not as red or puffy the next day. I plan to give this a good six months and decide from there, but as of right now I’m liking this addition to my skin care routine and it doesn’t interfere with the other goodies I’m using. Love your channel, Angie! Xxx
yes, I also have very nice results with calecim serum.. I am on my second bottle and will give a try with third also
One more vote for Calecim!
Would love to hear your opinion on Estriol creams - love the science👍🏻❣️
Is this the same as photozyme?
Please do a review of Estriol!!!
Thanks again for doing the hard work! Had several bad sunburns as a child, so not worth the risk to awaken any cancer cells, will keep using Trentinoin and sunscreen ❤❤❤
Have you looked into the anteage line. I have been using it for the last 3 to 4 months. Hard to tell if it's working. I feel like my skin looks better
Thanks for doing such excruciating research!
Thank you for all your research!
My pleasure!
Please review The viral VT reedle shot!!
Thanks Angie, so good to know and it was way to high of a price point anyhow. I would love a video on how to make our body skin look its best, currently I alternate between the Alpha Hydroxy lotion and the Goldbond Retinol but is there anything else that is helpful and effective?
Hi, I also use Alpha 12%Glycolic lotion as well as Goldbond Retinol lotion. I also do a body scrub once a week, then I shave, the I apply the GoldBond and or Alpha glycolic lotion. But Body Scrubs have really made a huge difference in making my skin soft, no more alligator skin etc.
@@karlaharvey2623 thank you, I have used body scrubs what is your favorite?
🏳️⚧️🚩🤓 nerd flag.
Now I'm kinda scared , I have been using the one from Reviv Skincare, I guess a dupe to the TNS. I have been using it for about 3 weeks, I hate to say this but my smokers lines have gotten less deep, also a big difference,and I don't know why, and my husband is the one who noticed, my lips are plump, not thin . But if it's bad for me, I would rather not use it. Oh no. Thank you for all the information. I love your videos 😊
Unless you have or have had skin cancer, have a precancerous skin lesion, have a history of skin cancer in your family, or maybe a lot of sun damage or a habit of not using sunscreen outdoors, I don't see any reason in what she said to freak out over using an EFG serum. You might try seeing if you can keep the results by using it less often, if that would make you feel better. That's my personal opinion, by the way, I'm not a medical type. I used a different "stem cell" serum for almost a year without any problems and ditched it because (1) it was a pain to use, and (2) that particular serum didn't do anything to my skin that I could see.
Use in combination with micro needling for optimal results!
Please explain because I just had micro needling
FYI - 1) Glycerin is less than 100 daltons and easily penetrates the skin. It’s cheap, easy, and effective. 2) Growth factors do not need to penetrate the skin to work since they exert their effects by binding to receptors on the surface of the skin.
Please consider collaborating with a dermatologist. We spend years studying (both in training and continuing education) the complex science of skin and would be happy to discuss. I really enjoying watching your videos to see what is out there on the market.
👍. I think we all welcome knowledge and informed opinions!
Thank you for your input about Growth Factor not needing to penetrate the skin in order to be effective.
Any other bits of information about all this stuff would be greatly appreciated!
Especially comments on the effectiveness of micro needling, lasers and radio frequency.
👍Thank you!
@@amy9864 The key with optimizing effectiveness of various in-office treatments is proper patient selection. As in, there’s no “one size fits all” solution. Identifying the exact issue you are trying to address guides choosing the treatment modality that best targets that issue. Other factors that affect treatment choices include skin tone (as darker skin tones typically have a higher risk of hyperpigmentation), skin type, and medical history (like autoimmune diseases).
Thank you for doing a deep dive on this subject. Very informative. As someone who has had melanoma twice, I will be steering clear of these products! ❤
I think that's a smart decision!
This was the perfect video to pair with my morning coffee. Your sciencey talks help me forget about my problems, much appreciated!
So happy it helped! & hope you have a better day! 💜
LOVED THE VIDEO !!!!
But …….. I want to use exactly everything you use. You are my heroe
Thank you!! I used to use a growth factor I did my research and now you confirmed it glad I stopped! Stick to my vitamin c and tretinoin. Actually after years of Botox going to take a break and if my face goes back to baseline. Lol hope I don’t regret it 😊❤❤❤❤
I use Ultimate Serum with Exosomes from Revive serums company. It contains growth factor. I see the difference. I use it every second day.
Thanks for this. I have been using Stratia peptide cream and I must say I like it. Reasonably priced and you do not need much. Great pump bottle too.
I am 99% sure that my husband was in a Skinmedica TNS clinical trial. To be in the clinical trial you can't be using any other anti-aging ingredients. He was given a face wash, TMS and sunscreen. Every questionnaire he said that it stinks. He did have improved skin appearance.
So it worked? Unclear because you also said it stinks. Just confirming. TYVM.
@n0tgunshy the product did stink. The 1st bottle smelled the worst. It was a paid 12-week clinical trial. You keep a daily diary. A dermatologist grades your skin. Most of the time, the company that is conducting the clinical trial doesn't know what the product is. There is an in-between company that brokers the clinical trial. My husband did show great improvement in his skin appearance.
Thanksnfor confirming what I thought tried Skin Medica back in 2013, and didn't see any amazing results. The COST IS OUTRAGEOUS. Have you deep dived Cosrx? Just turned 60 with very dry skin. Looking for fine lines and deep wrinkle help. Finally broke down and got the Snail 96 Mucin and eye cream. Was impressed with the hydration. Then I saw a utube video on Cosrx The 6 Peptide Skin Booster so I purchased the peptide along with their Spa Mask and All in one cream. 1st use of the peptide serum I saw immediate plumping of my deep forehead wrinkles. I've only been using less then a week but I'm impressed. Plays well with my Ordinary Retinol. Help with large pores that I've developed post menopause. All products purchased on Amazon at reasonable prices. Would love to know your thoughts. Thanks for your deep dives and time. ❤❤❤
Please comment on Reviv Serums “Ultimate Serum”. Has growth factors and exosomes. Much cheaper than TNS, and much the same ingredient deck.
I hadn't seen your 2017 trial of TMS, and before your video started my first thought was that I did try a full bottle and saw zero results. Glad I'm not alone. Instead of buying it, I can save that money and get another Halo laser where I actually did get amazing results. And of course Tret and sunscreen
TNS
A laser treatment is definitely a better use of that money than a bottle of TNS (IMHO) 💜
absolutely love your looking at the science behind. you do hard work for us. thank you so much. I had followed you since pretty much the beginning of you on youtube. other's come and go, but I always have you in my corner.
Thanks so much for this deep dive, as always. I’d be really interested in efficacy of topical rooibos tea - it’s antioxidant benefits compared to vitamin C, aha benefits, zinc, etc. Thanks for your content! 🫖🧴👸🏽
Hi Angie! I'm interested in the new more stable form of squalane. Apparently it is not the same as squalene. I love your nerd videos, thank you! ❤❤❤
As always l bow to thee O Skin Oracle.🎉 Not only for your wonderful deep dive research but also your flawless presentation and communication of all you've found. No one has more clarity. Thank you! 😊
I use Vitamin C serum, then Copper Peptide serum, then I apply Trentinoin .05%. I think it does a great job!
So sorry I doubted you Angie! Going into this video I wasn’t sure if you were going to do the right thing. But you sure came fully prepared and I am so impressed with the time you took on the research and the variations of papers you sited plus your own experiences! You are the goat!
I used tns for years . Since 1998 . I stoped because of the high cost . I use Agency now for a year . Its affordable and my 66yr old skin has improved quite well . Thanks Angie .
Just use tretinoin and estrogen/estriol.
@@theseeker1948 What doctor prescribes estrogen cream for anti-aging? Or is there some over the counter ones?
Great info as usual. More info on estradiol cream for face please. And more info on how great your hair looks.
Thank you, Angie! Have you seen the Jovs laser mask? I know you love the onmnilux but curious if you would test/try Jovs to see if it’s even better ❤
Hi Angie. I have been watching you for years now and I thought I would ask if you know that Tretinoin causes hair loss. I tried for over year and half and it has caused me to lose my eyebrows three times..I stayed off of it and restarted in September and again lost my eyebrows..I was a sun worshiper also and have wrinkles around my mouth which I hate but not at the cost of my eyebrows...This is so weird..I found another person on you Tub ,Pampered wolf and she had same issue..No one else seems to have that symptom. Thanks for any help...
Angie, thank you for that very well researched and informative take down. And yes, I am a nerd, but I really didn't want to have to do this deep dive. Keep up the excellent work.
LOVE the in depth review of EGF. They're definitely flooding the marketplace! BUT, everything I have seen supports their efficacy! The one saving grace is most of them are out of my price range! I use stratias interface, not bcz of the egf, but bcz of the multipeptide benefits and it is a very nice cream. You look beautiful as ever, Angie! Thank you for such a wonderfully educational video!
Have you made a video on how to get rid of the marionette lines, nasolabial folds, and the 11's? I see that you don't have these. If you have made a video on these problems please can you show me? And if you haven't made a video on this, can you please make one? Your skin is mind-blowingly amazing!
Yes! I tried TNS about 20 years ago... stinky, stinky... I couldn't stand it! And no difference in my skin at 40 years old... at 61, I am going to stick to tretinoin and peptides. Thank you for your expertise!
I tried it years ago. I felt it tightened my 42 yr old skin, but the smell was disgusting. Only used one bottle.
Not what I expected! I’m glad I watched to the end bc I almost skipped straight to the links you shared to buy something you were sharing in the description box 😱
NO WAY will I be adding a pre-existing-skin-cancer-developer into my skincare routine 😳 (Maybe adjust the title to this one?) Love you AHF!! And thank you for your research! You’re my hero ❤
I’ve been using TNS for 6 months along with the rest of my arsenal and even though it’s a fortune, I see a difference. 64yo.
I’m 62 and noticed a big difference when using Necutics BioFirm on my neck so I will be sticking with it. Thank you for the review though.
thanks Angie! Glad to see the 500 dalton rule & (all) peptides addressed. I remember learning at some point that one particular company solved this (Alastin) but, unless and until I see the people I trust address this, I won't spring for it. Really appreciate you taking a deep dive.
I love watching your videos. They are a good place to start in trying to figure out what is good and what is questionable to use on my skin. At 61, almost 62, I am extremely happy with products from Oil of Olay and L'Occitane. I feel some things are just not tested enough and some "growth factors" are extremely scary and dangerous--like cancer cells. What gets swept under the rug with many of these outrageously expensive products and are not properly addressed are genetics, environment, and living/dietary habits. How much does eating a hamburger or other junk food age your skin? Doctors are imperfect people as well. Remember when doctors claimed smoking was good for you.
About 10 years ago I would regularly get chemical peel facials every 5 weeks, which left my skin feeling a bit sensitive, and I would have some light skin peeling. The Skinmedica TNS Recovery Complex, which I finally tried after a couple of the facial treatments really did make a difference in the time it took for my skin to feel and look better. I am sure the peel itself helped with fine lines and wrinkles as well as sun damage in general. So maybe the growth factor complex helps with “injured” skin, and not so much with normal skin? Maybe they could also help if someone was having seriously deep microneedling? For now I stick to tretinoin and sunscreen, plus some occasional hydroquinone. And BBL every now and then. Thanks for all your research!
Women who never or seldom use good quality skin care products will likely see the most improvement. Women who've had long term, consistent, good quality skin care will likely see less significant change. It's the law of diminishing returns in my experience and opinion.
I’m also 62 and for the past few years my skin has become hyper sensitive. I had to stop my prescription tretinoin . I’m trying to reintroduce retinol slowly but am getting red, raw and flaky patches from .25. I’m only using once a week like I did when I first started about 10 years ago. Any ideas ?
I use ZO growth factor after my Altreno Tretinoin at night then moisturizer. It is more expensive than tretinoin at $160 something I think. It was recommended by my esthetician at the dermatologist office I go to, It seems to help. It sounds funny but they advise you to use last in your routine before moisturizer. I asked her to write it down to follow and try to keep my nighttime routine easy with a great skin barrier emollient & lipid replenishing moisturizer. Better she pointed out to use one expensive product that works that alot of others that are cheaper that dont work. Is there any certain moisturizer you love after tretinoin? I have using ZO growth factor serum about 2 or 3 years.
Thank you so much! That was very helpful to hear the whole story & not just the bits & pieces that float around! I love that you always do your research & that is one of the many reasons I have been watching you for years! Thank you for all the thousands of hours of time, research & effort you go to help keep us informed! Love watching all of your videos! 🙂
I HIGHLY recommend Plated Skincare Science. It has dramatically changed my skin texture, dark spots and dryness in 4-6 weeks!
Excellent video! Thank you so much for all of the deep and scientific information to provide evidence. I have used Neocutis off and on for a few years. I mostly use it after a treatment that provides a small window of opportunity for the serum to slightly absorb. I have never thought about growth factors affecting possible skin cancers. So, I will now only be using my C, retina, HA, and spf. Thank you for all the time and research that you put into this!!❤
Thank you so much for this! Looking forward to your review on estrogen cream. Please consider reviewing DNA repair serums. I recently incorporated one and would like to hear your thoughts. Thank you for all you do! You’re amazing ❤