Killing Cancer Cells with the Help of Infrared Light - Photoimmunotherapy
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- เผยแพร่เมื่อ 16 พ.ค. 2016
- Near-infrared photoimmunotherapy uses an antibody-photoabsorber conjugate that binds to cancer cells. When near-infrared light is applied, the cells swell and then burst, causing the cancer cell to die. Photoimmunotherapy is in clinical trials in patients with inoperable tumors.
For more information, please visit www.cancer.gov/photoimmunotherapy - วิทยาศาสตร์และเทคโนโลยี
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This is so far the ONLY conventional cancer treatment that I would ever consider. All I know is, it cures back pain very well.
Thank you for your comment. While this is exciting news, this approach is not conventional or available as standard therapy. It’s presently being studied in an early phase clinical trial. NCI researchers are hopeful that the trial will provide more definitive information on the promise of this new treatment approach.
I believe Dr. Michael Weber in Germany has been doing this for some now...he and his clinic seems to be a leader in Photodynamic therapy.
Excelente video. Obrigado.
Gotta stop those creatures.
It is a very well design video , as far as graphics and animation , but can you provide actual patients , and their statements , tnXD
Brilliant.
Why people dont know about this since 2016? 21,892 Views and the latest PoP song has million views on youtube.. Please Share usefull information and innovative technology.. Its just more important
Peace
I totally agree.. those song not going to save ppl
what about infrared light on breast tissue without taking the conjugate? sounds like it might be of use in general. i know infra red light helps build collagen and rejuvenates skin.
OH wow this looks very promising
PDT(Photodynamic Therapy) is as another therapy for tumor . How about efficiency and safety as compared to PDT ?
A new technology.
I live in Brazil.
I was looking into how lymphoma has a connection to Prurigo Nodularis, and I am wondering if this may help sufferers of Prurigo Nodularis. 🥂 & 🙏 to the trial going well and it getting successfully and inexpensively to patients ASAP. Thank you.
Thank you for your comment. The following resource does list lymphomas as systemic diseases that Prurigo Nodularis can be associated with. This resource is available from the National Organization of Rare Diseases at rarediseases.org/rare-diseases/prurigo-nodularis/#causes. Any patient concerned about their cancer risk should speak with their doctor. Take care.
what are Type of special receptors that found on cell membrane of tumor cells ?? and found in all types of cancers or some?? this info not found in article . thanx
I think that special receptor must be developed for each types of cancer.
Can you please be more specific on what you would call a inoperable tumor? If the operation is of highly invasive surgery and is the only was to get to the tumor wouldn't that be inoperable? What kind of tumors could this treatment be used for? What is the prognosis of patients who have been treated with photo imunal therepy? Where in the US is it currently being used? What was the year that it started being used?
Hi Aaron, NCI’s resources refer to an inoperable tumor as a tumor that cannot be treated with surgery. In asking about the uses of photoimmunotherapy, there are currently four clinical trials in the US using this treatment approach. All trials are focused on either head and neck cancers or squamous cell skin cancers. You can view these trials here: clinicaltrials.gov/ct2/results?term=photoimmunotherapy&cntry=US&Search=Apply&recrs=a&age_v=&gndr=&type=&rslt=. You can learn more about the development of photoimmunotherapy in a blog post from 2016 at www.cancer.gov/news-events/cancer-currents-blog/2016/photoimmunotherapy-cancer. Additional information about the recent approval of photoimmunotherapy in Japan can be view at ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. Take care.
How has this therapy method been doing yet ?
Dear Pelle, The following article provides an update about the progress that has been made in photodynamic therapy research: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. This method of treatment continues to be studied in clinical trials to further understand its use as a cancer treatment. Take care.
Ouch - looks very risky to relase tumor DNA and RNA into the rest of the body!! :-(
okjhum you know what’s even more risky? Cancer!
Have they made any advancements since you posted this video?
Hello, in 2020 a device and drug combination based on photoimmunotherapy development that was led by Dr. Kobayashi was granted approval by the Ministry of Health, Labour and Welfare in Japan for the treatment of unresectable locally advanced or locally recurrent head and neck cancer. Approval of this same type of photoimmunotherapy by the U.S. Food and Drug Administration will depend on the results of a larger phase 3 trial. You can read more about this at ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. You may also wish to explore PubMed®, a free search tool of the National Library of Medicine, to search for journal articles with updates on photoimmunotherapy at pubmed.ncbi.nlm.nih.gov/ . Take care.
Does anybody know how effective this treatment has been for advanced melanoma skin cancer
Hi Kevin, Photoimmunotherapy is a new type of immunotherapy and has not yet been approved for any cancer in the United States. This therapy has primarily been studied in patients with head and neck cancers (for example, those inside the mouth, throat, and voice box). Although there are ongoing clinical trials looking at other types of cancer there are currently none listed for melanoma in the NCI’s database of clinical trials at www.cancer.gov/about-cancer/treatment/clinical-trials/search. The following article provides an update about the progress that has been made in photoimmunotherapy research: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. Take care.
Do you use red light or infra red light? What nm of light? What output of power?
Hi Saini, this is a novel type of cancer immunotherapy that uses infrared light to activate rapid and selective killing of cancer cells. You may read more about this research at www.cancer.gov/news-events/cancer-currents-blog/2016/photoimmunotherapy-cancer.
Hi I am little desperate my Father is diagnosed with cancer in neck is it possible to know if i can sign up or use Dr Kobayashi trial ..any info will be greatfull
Hello, We are sorry to learn of your father’s diagnosis. Dr. Kobayashi conducts laboratory and animal research but does not treat human patients. However, there is one clinical trial (research study involving humans) in the U.S. using photoimmunotherapy for recurrent (previously treated) head and neck cancer, which you can read about here: clinicaltrials.gov/ct2/show/NCT02422979?recrs=ab&cond=photoimmunotherapy&cntry=US&rank=1. Additional information on clinical trial participation is available in this link: www.cancer.gov/about-cancer/treatment/clinical-trials. We encourage you to discuss this information with your father’s doctor regarding how it relates to his specific situation. Take care.
@N W - Did you use this form of therapy? Did it work?
WHERE CAN WE GET THIS THERAPY?! My husband has stage 4 lung cancer but no tumors… just in the cells in the fluid. PLEASE LET US KNOW ASAP!
Hi Mary, we are sorry to learn of your husband’s diagnosis with lung cancer. Photoimmunotherapy is a new type of immunotherapy and has not yet been approved for any cancer in the United States. This therapy has primarily been studied in patients with head and neck cancers, and although there are ongoing clinical trials looking at other types of cancer there are currently none listed for lung cancer in the NCI’s database of clinical trials at www.cancer.gov/about-cancer/treatment/clinical-trials/search. The following article provides an update about the progress that has been made in photoimmunotherapy research: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. To learn more about lung cancer treatment you may wish to explore the treatment summary and research links at www.cancer.gov/types/lung. We also invite you to contact the NCI’s Cancer Information Service for further information www.cancer.gov/contact. We wish you and your husband the best.
Hold on, could someone tell me if this works with near infrared therapy ? or will one need to take injection in order to benefit. My dog cancer has only grown since been exposed so im almost praying for this to be the case for me.
Hi Nanne, We are sorry to learn of your dog’s diagnosis with cancer. You may wish to discuss treatment options with your dog’s veterinarian and review information from the U.S. Food and Drug Administration at www.fda.gov/consumers/consumer-updates/my-dog-has-cancer-what-do-i-need-know. We wish you the best.
Hi. Is near infrared or far infrared sauna effective for cancer?
Hello, we are not aware of any scientific evidence that near or far-infrared saunas are an effective treatment for cancer. Tips on how to find cancer resources you can trust are available at www.cancer.gov/about-cancer/managing-care/using-trusted-resources. Take care.
So after several year of test what is the output?
Hello, The following article provides an update about the progress that has been made in photoimmunotherapy research: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. Clinical trials in the United States using photoimmunotherapy are ongoing and you may wish to explore PubMed®, a free search tool of the National Library of Medicine, to search for journal articles with updates on photoimmunotherapy at pubmed.ncbi.nlm.nih.gov/. Take care.
Would this be useful for late stage 3 pancreatic cancer? If so is there a price range?
Hello, Photoimmunotherapy is a newer type of immunotherapy and has not yet been approved for any cancer in the United States. This therapy has primarily been studied in patients with head and neck cancers (for example, those inside the mouth, throat, and voice box). Although there are ongoing clinical trials looking at other types of cancer there are currently none listed for pancreatic cancer in the NCI’s database of clinical trials at www.cancer.gov/about-cancer/treatment/clinical-trials/search. The following article provides an update about the progress that has been made in photoimmunotherapy research: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. Take care.
What's the status of this treatment in 2021 or was it just another "funding endeavor"?
Hello, As of 2020, the Ministry of Health, Labour and Welfare in Japan has approved photoimmunotherapy for the treatment of unresectable locally advanced or locally recurrent head and neck cancer. Approval of photoimmunotherapy by the U.S. Food and Drug Administration will depend on the results of a larger phase 3 trial. Photoimmunotherapy is also being explored as a treatment for other types of cancer. You can read about these updates at ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer#:~:text=A%20device%20and%20drug%20combination,Japan%20for%20the%20treatment%20of.
My mother has stage 4 adenocarcinoma of the stomach and I read red light therapy should not be used for carcinomas. Is this true??
We are sorry to learn of your mother’s diagnosis. We encourage you to discuss your questions and concerns with her doctor. This video discusses photoimmunotherapy, which is a novel type of cancer immunotherapy that uses infrared light to activate rapid and selective killing of cancer cells. When the light is applied, the cells swell and then burst, causing the cancer cells to die. This is a new type of treatment still being studied in clinical trials, primarily for head and neck cancers. One limitation is that although near-infrared light does penetrate tissue, it cannot penetrate deeply, and would not be appropriate for all cancer types. You can read more at www.cancer.gov/news-events/cancer-currents-blog/2016/photoimmunotherapy-cancer. Take care.
is this a research or photoimmunoterapy is started to being made on patients ?
Photoimmunotherapy is not widely available. Currently, one early-phase clinical trial (research study) is underway using photoimmunotherapy in the treatment of recurrent head and neck cancers. Information on this trial can be found at clinicaltrials.gov/ct2/show/NCT02422979?term=photoimmunotherapy&recr=Open&rank=1. You can review additional information on photoimmunotherapy here: www.cancer.gov/news-events/cancer-currents-blog/2016/photoimmunotherapy-cancer. Take care.
Are the intracellular contents dangerous once released into the body?
The goal of photoimmunotherapy is to kill cancer cells and a patient’s body is able to break down and remove dead cells without causing harm to the body. Photoimmunotherapy is still under study and researchers will continue to learn more about any possible side effects caused by this treatment approach. Take care.
Is it not an issue that cancer cells spill their necrotic content into the bloodstream? When surgeons operate to remove a tumor they always want a margin of healthy tissue and say stuff like "we think we got it all". Isnt bursting a cell just a form of metastasis?
It is understandable to be concerned about necrotic cells entering the bloodstream. When the damaged cells die, they are broken down and removed by the body. When a cell is damaged by the process of near-infrared photoimmunotherapy, it dies and loses the ability to spread and grow in other parts of the body. You can learn more about this treatment approach at www.cancer.gov/news-events/cancer-currents-blog/2016/photoimmunotherapy-cancer. To your second question, the chance that surgery will cause cancer to spread to other parts of the body is extremely low. Following standard procedures, surgeons use special methods and take many steps to prevent cancer cells from spreading during biopsies or surgery to remove tumors. For example, if they must remove tissue from more than one area of the body, they use different surgical tools for each area. Information about how cancer spreads can be found here: www.cancer.gov/types/metastatic-cancer. Take care.
Does it apply to brain tumors?
Hi Fotis, Photoimmunotherapy is a new type of immunotherapy and has not yet been approved for any cancer in the United States. This therapy has primarily been studied in patients with head and neck cancers (for example, those inside the mouth, throat, and voice box). Although there are ongoing clinical trials looking at other types of cancer there are currently none listed for brain tumors in the NCI’s database of clinical trials at www.cancer.gov/about-cancer/treatment/clinical-trials/search. The following article provides an update about the progress that has been made in photoimmunotherapy research: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. Take care.
Would the drug reach tumor in breast tissue ?
Hi Crystal, Photoimmunotherapy is a new type of immunotherapy and has not yet been approved for any cancer in the United States. This therapy has primarily been studied in patients with head and neck cancers, although there are ongoing clinical trials looking at other types of cancer. Because there is much we do not know about this type of cancer treatment, we are unable to say if this treatment would be effective on breast tissue or one day be given to breast cancer patients. You can read more about recent news on photoimmunotherapy here: ccr.cancer.gov/news/article/japan-approves-photoimmunotherapy-for-head-and-neck-cancer. Take care.