As in histamine ethyl chain occurred so the H1 antihistamine should proceed with same. If you increase the length of chain this produce pharmacophore required for binding to mus- carinic as well as adrenergic and serotonergic receptors too more than histamine receptor so showed sedation and antidepressants action
Reference of Most of the medicinal chemistry lectures are Foye's Principales of Med. Chem, Alagarsamy's Textbook of Med. Chem, Ashutosh Kar's Medicinal Chemistry etc
Note on General Sar Of Antihistamine.
What answer.......
Yahi notes likhenge
Great❤
Very helpful video 💯✌🏻
Thank you so much Sir ❤️
Thanks for watching, keep watching and share to needful students
vary helpful video ,SAR is clear Thanku sir
Thanks dear. Keep watching.. and share to needful students
sir Tripelennamine structure hetro aryl compound ki bounding wrong hai
Wrong str.
So perfect nd very helpful ❤️
nice sir so helful video
Thanku sir 😊😊😊😊😊😊
Thank you Sir 🍀 it's very helpful 🌷
Thanku sir ji
Thanks sir
Can you please give a link of pdf through goggle drive .... because many students not using Facebook
Thank you so much sir
Sir ye first aur second generation dono ke liye hai
Ji
Nice sir
Apki kripa hai
❤❤❤
Why antidepressants/Antipsychotic action shown by drug when homologation is occure in ethyl chain
As in histamine ethyl chain occurred so the H1 antihistamine should proceed with same. If you increase the length of chain this produce pharmacophore required for binding to mus-
carinic as well as adrenergic and serotonergic receptors too more than histamine receptor so showed sedation and antidepressants action
@@parjanya24 thnku🙏
Sir suggest best reference book for medicinal chem.
Arey you B. Pharm student ??
@@parjanya24 yes sir
Tq sir
Chlorcylzine me ethylene chain kyo nhi hai??
It's an example of One one carbon in between nirogen and Phenyl ring
Sir file download ho jati hai but open nahi ho rahi
Ohh. Open in laptop, or join us on telegram will upload all pdf there
Sir please reference ke baare me bhi bta diya krne
Reference of Most of the medicinal chemistry lectures are Foye's Principales of Med. Chem, Alagarsamy's Textbook of Med. Chem, Ashutosh Kar's Medicinal Chemistry etc
Txn sir
Thanks dear . Keep watching and share to needful students
HAp -i video uplod kijiy
Information bohut hi kaam hai .. baas Thora hi information hai .. is se result nehi banega !
Thanks for the comment. This is topic only on SAR of H1 Antagonist which is sufficient for B. Pharm examinations as per my experience.
@@parjanya24 👍
Thank You Sir