What they didn't explain in this video is that yes, they can extract DNA from the little pup, but it is broken segments of DNA, not perfect, complete strands. However technology is advancing so quickly, that even gaps in the DNA can be patched with DNA from the closest living relative. Others have commented on this in this videos comments section. I'd love to see us start bringing animals back from extinction - the Dodo and many others - start undoing some of the damage we have done. Hope the human race can learn to tread more lightly on the planet, consume less, recycle more, produce less pollution, and start having a lot more regard for the environment, plants, animals we share our wonderful planet with. P.S. I have 100 acres of land that I have set aside as a nature reserve and have taken decisive steps to ensure my family does the right things for the environment and our planet.
Sadly, there are no living relatives close enough. I too used to have this hope. But a species is so much more than its DNA. There is no creature alive that could teach it how to be a thylacine. 😢
I’ve been so fascinated by this animal ever since my Dad introduced me to the animal in 2009. I sincerely hope we see a cloned Thylacine within the next 20 years!!
I don't. What kind of a life would they live? Humans feel guilty, that's why they want to "bring back" thylacines. Protect and preserve the remaining endangered species
@@genkestrel7254 your not understanding this could also save the ones that are endangered as well there's some that most likely just might be gone recently cause we haven't been able to spot some endangered animals in a min they just haven't been placed as Instinct because of the hope that they are not gone already
And a marsupial would likely be the first candidate for an artificial womb, since they only need to gestate for a couple of weeks, instead of months for placental mammals.
They do actually have artificial wooms now ,but they still in the beginning stages sort of thing. I saw a story about men using sex robots and artificial wooms because it's less hassle than dealing with a actual woman these days, and there's men who want to have children even if they haven't found the right partner just the same as how women use sperm donors and things . And especially with gay men these days and how allot of kids that think they are trans are getting doctors to sterilize them and take away there ability to reproduce in the future when they grow out of it and change their minds.but they've already been butcherd by doctors and uses as political pawns by politicians
That is not the biggest limiting factor here. Without close relatives to compare, our understanding of its genetics and development will be very limited. Colossal biosciences' proposed method of genetically modifying the Dunnart will require a huge number of simultaneous gene edits to get anything close to a thylacine. And then you have to consider all the non coding DNA that is essential for proper gene regulation and function. I am skeptical to say the least
@@jacobleese282 yes our technology and understanding of genetics isn’t there yet. Perhaps by the next 2 decades. Since cloning already existing mammals is already hassle.
Jokes on this guy, they are actually working on bringing them back, with the Fat Tailed Dunnart (Sminthopsis crassicaudata), the closest living relative, being the surrogate. They have the entire genomic sequence complete too from my understanding
Naaaahhhh... you've got it wrong. The Thylacines went into hiding. Why? Because they are in control... of everything! They are running the joint from behind the scenes. Thylacines are clever and cunning. They are currently working on secret deals with the Chinese, Putin & Donald Trump... but that's a story for another day. ☢️ 🧤 🕶️
@@normalperson5356 Marsupials are small when they're born, so that wouldn't really be an issue. Ever seen a newborn kangaroo? They're smaller than mice! I think the scientists got this covered haha, but it's fun to look into
@@imle9279 yeah, and I have a feeling it would be a surrogate only for the fetus, and the pup would be hand raised from the moment it was born. The dunnart may also be able to provide viable eggs to put the clone material into, since as far as I know we can't produce those artificially yet. But I haven't looked into the details of bringing back the thylacine so I'm not sure what their plan is exactly. I might do some reading later. The scientists working on this are still quite a long way off from what I understand. What's exciting is that they're looking at refining their "de-extinction" tech on animals that are functionally extinct, but not physically extinct. Basically, there are living animals, but too few of them to repopulate naturally. The plan is to use this tech to artificially create genetic diversity and prevent the genetic issues that can happen with extreme inbreeding, so that species that only have a dozen or fewer individuals left can potentially make a comeback.
@@willw9691 why bring something back from the dead why not introduce endangered species to new places kinda like invasive species so they can adapt and thrive
@@Shawn64999 lol because that's also worked in the past your clearly not very knowledgeable on what that does to an environment so clear example introduced rabbits for hunting rabbits went rampant introduced foxes to control them now they are both out of control foxes killing native animals also introduced cane toads to control pest beetles in the sugar cane now they are out of control same for wild pigs & buffalo you don't introduce a species to a new habitat that cant be controlled by a native species and we don't have big predators apart from crocs that cant fully control them as they are water based predators & now here you also have issues with feral cats & dogs which are killing off vital native wildlife because people are incompetent at looking after animals & i am not saying thylacine will be able to control dogs, pigs & buffalo but they will be able control foxes rabbits & most likely cats which may cause them to adapt to killing off those species over native due to the abundance of them so please don't talk about things you have no clue about your the reason why people think its ok to introduce foreign animals without assessing the damage they will cause to an ecosystem please don't reply i wont respond to you an longer i have clearly shown why you shouldn't have a voice on this matter because you don't understand ecosystems
We only have lost so many types of mammals because we have had the most diverse group of mammals in the modern era. Most other countries have had a huge amount of mammals that they killed off before keeping records of them.
I'm guessing feral cats and foxes have a very large role to play there too. I find it so frustrating that governments don't seem to want to do anything about it. My home suburb, home to a small nature reserve, was supposed to have had a fox cull a little while back, which was nixed due to animal welfare protestors. But these people failed to consider that although death for one fox may not be nice, one fox will kill dozens or hundreds of native animals (and pets - including my own birds) every year, and all those animals will die horrible deaths. Foxes don't kill kindly; they just rip live animals apart. Likewise, in the ACT adult cats must be desexed unless you have a permit, which helps reduce feral numbers. I don't understand why this kind of legislation cannot be enacted elsewhere.
What’s your excuse for gold fish and carp destroying your water ecosystems? And the several marsupial species that have bin killed? Who released and shipped the rabbits to hunt? Kangaroos? Couldn’t be the people’s fault oh no not like the whole country in 1800s was covered with convicted felons shipped from Europe 🤡 not like they failed a whole war with the emu’s which they would of gladly added to the extinction list and planned too
Never say never when it comes to science. I’m surprised he didn’t qualify that statement. Like we couldn’t just genetically engineer a womb that wouldn’t reject the Thylacine embryo.
Well that was super depressing. I’m not giving up on the Thylacine coming back , if it’s not already been done in some secret underground lab somewhere! 🐅
There's a small chance they never went extinct just been hiding really well from humans after we starting killing them like every other species if animal.
I'm so glad someone finally said the hard truth about whether thylacines could be brought back. While the idea of bringing back the thylacine is really cool, programs that talk about it never lay out all the hurdles in the way. First hurdle, you can't clone dead cells. If you don't have a sample taken from a living animal that was preserved, you're pretty much out of luck. Another option is to find the closest living relative of the extinct animal and modify the DNA within the egg and sperm cells of that species to replace the DNA that separates the two species to be the genes of the extinct animal, then have the close living relative act as a surrogate. This is how scientists have proposed bringing mammoths back. The closest living relative for the thylacine is the numbat. They last shared a common ancestor 38 million years ago. Second hurdle to bringing back the thylacine is the lack of a surrogate. Marsupials only gestate for about 38 days, so even if an artificial uterus could be invented, that only covers the very first part of the development. Joeys below a certain age have never been successfully hand-raised, so not only would an artificial womb need to be invented, but so would an artificial pouch. Third hurdle, milk. There are no marsupial species alive today that hold a similar ecological niche to what the thylacine did. Not only that, the composition of marsupial milk changes at every stage of a joey's development, which is one of the reasons why joeys below a certain age have never been hand raised. Finding the correct formula for every single growth stage would be a struggle, and likely result in many clones dying.
@@teleriferchnyfain I studied genetics for a few semesters in university, but I'm not a geneticist. I'm from Australia and I wanted to be a wildlife rescuer when I was a teen, so I did research about raising joeys. Before the joey develops hair (often around 5 months old) it is simply impossible to keep them alive in human care. They are so fragile that only their mother's pouch can keep them alive. A perfect example of this is that there was a program here in Australia (not sure if it's still ongoing) where joeys from a critically endangered wallaby were taken from their mothers a few days after their mouths stopped being fuzed to the mother's teat (yes, the mouths of joeys quite literally fuse to the teat for the first month or so of their life) and transferred to the pouch of surrogates of a different wallaby species. When that happened, the joeys of the surrogates had to be euthanised because marsupials only produce milk in the teats currently in use. If you want them to raise a different baby, one of their current ones has to disappear.
I hope we can restore the Thylacine back to nature. We owe it to nature to bring them back after we removed them from nature. Despite the negative outlook of this scientist, we are doing things in science no one thought possible even 10 years ago. I am more optimistic than most we will succeed with the Thylacine and many others in the future!
Artifical wombs are possible, there is a guy that grew a chciken named rambo in a petri dish. It not only started off as a cell in the dish but also grew to a baby chick and thrived beyond.
He says no it can't be brought back but just recently one organization said yes in the next four to five years they will do it. I am guessing though if they do it it will be just a hybrid thylacine and not a 100% version. Kind of a replica but not the true version if you get my anology.
Thylacine both mainland and Tasmanian continue to exist with over 10 000 independent sightings. Infact Tas gruberment hold its status as extant not extinct. BTW although it's a wolf and also a marsupial so therefore the term pup is incorrect because it's pouched young are infact termed joey. Many prints on photos and casts of I do have. How do I upload a picture here?
Wolves and marsupials are completely unrelated animals. Thylacines are marsupials with a convergent evolution to look similar to canines superficially.
The fact they spend such little time developing in the womb actually makes marsupials the hardest to bring back. In the first few months in the pouch, the mother's milk basically changes from week to week, which is nearly impossible for humans to replicate. This is why if a marsupial joey is orphaned below a certain age, no matter the species, it will be euthanized because there is a 100% death rate for young joeys in foster care because we simply are incapable of providing what they need.
@@DragonFae16 You find a surrogate, after all plenty of animals can survive on other species milk, just drop it in a kangaroo. Not saying it will be the pinnacle of health or anything.
@@CMZneu A kangaroo could only be used as a surrogate for another macropod. And you'd have to use a kangaroo that has a joey of the same age as the orphaned one, remove the baby the kangaroo already has and discard it (which means euthanising it), and replace it with the orphaned joey. Kangaroos don't have twins and can only carry a single joey in their pouch at one time. And in fact, to boost the numbers of a critically endangered wallaby, that's exactly what is being done. Joeys that are about 2 months old are being taken from the pouches of their mothers to free the mother up to breed again. The joey is then flown to a zoo, where a captive population of common wallabies are. The chosen surrogate is sedated, her joey is removed and the foster joey is put in its place. The removed joey is then euthanized.
With the advances being made in genetics research alone, it will be possible one day to achieve what was once thought impossible. Not so long ago the human genome was mapped for the very first time, a discovery that was unthinkable at the time. They are now theorising that babies will be born in the future in artificial wombs. The pace of technological advancement in the field of science regarding cloning in the last 30 years alone, has been astonishing. Whilst it may not be in our life times, the reality of cloning a thylacine is increasing with each new breakthrough in this field of research.
How can they store these Thylacine bodies so they don't decompose (rot)? If the use a preservative, wouldn't that affect any sample they wanted to obtain for the DNA (wouldn't the preservative be included)?
As of October 25, 2023, scientists are working to bring the Tasmanian tiger as well as being close to bringing back the mommoth.also known as the thylacine, back from extinction by 2028. The last known thylacine died in captivity in 1936, and the species was declared extinct in 1986. However, no confirmed specimens have been found since its extinction, despite rumors of its survival. The project involves several steps, including: Constructing a genome: Create a detailed genome of the extinct animal Comparing genomes: Compare the genome to that of the thylacine's closest living relative, the fat-tailed dunnart Editing DNA: Edit the DNA of living cells from the dunnart to match the thylacine Creating an embryo: Use gene editing technology on the tiger genome to create an embryo Using stem cells: Use stem cell and reproductive techniques to turn the edited cell back into a living animal According to Andrew Pask, who oversees the TIGRR Lab at the University of Melbourne, it could take his team until 2033 to create a thylacine-like cell, and it may be decades after that before the first Tasmanian tiger proxy is born
Even if it could be done it would lack the opportunity to learn things like thylacine hunting behaviour (how much do we even know about that) which it would need to survive in the wild.
Sad situation that we allowed this magnificent animal to become extinct. It was too late when the government stopped paying generous bounties for killing them. I think there is a high probability that more existed in the wild, after the last died one died in captivity but they are gone now.
How can they smile? The way we exterminate entire species from existence is utterly heartbreaking. The thylacine is just another lesson humanity fails to learn, over and over. 😔
Maybe it was our grandparents generation, but there are 100s perhaps to 1000s of species that we are even aware of that have become extinct since we were born. So offended or not, we certainly fail to learn.
Nature and the changing climate has killed millions of times more than humans ever could yet you're not angry on nature and it's brutality. If nothing you should be happy we are trying to fix mistakes from the past since terms like conservationism of fauna are recent concepts humankind was never familiar or interesed with.
I too wish that humans were off the hook. I wish that the 30% of amazonian forests destroyed since 1973 was just part of a natural climate shift. If we continue to avoid responsibility as humanity, then we will stay on the current tragectory, and the remainder will be gone within 20 to 30 years. Maybe you are okay with that and are content with this knowledge. Most of the world is. But personally, I'd argue we need an immediate and drastic change in practice. How we relate to our world and our delicate connection to the earth and its plants and animals... we need a massive paradigm shift.
It's not. Dunnarts are equally "close" to the thylacine as any other dasyurid (like Tasmanian devils, quolls, or antechinuses) - or, for that matter, as "close" as the numbat is. All dasyurids share a common ancestor to the exclusion of the thylacine, which means that they are all equally close/distant to it - they are more closely related to each other than to the thylacine. The numbat is in what is called a sister group to the dasyurids (that is, they are the other side of that branch - when a lineage splits into two groups - branches off - those two new branches or groups are called sister groups). This means that the numbat shares a common ancestor with the dasyurids... to the exclusion of the thylacine. And of course, this means that the numbat is equally close/distant to the thylacine as is the fat-tailed dunnart, or the Tasmanian devil. They are all not very closely related! The thing with the fat-tailed dunnart is that it is well-known, easy house in a lab, and the researchers have been doing deep dives into its genome and developmental biology, so it's the Aussie mammal version of a lab rat. In other words - it's the Aussie marsupial who's "genomic puzzle" we know most about, so changing those puzzle pieces would be easier. Another thing (which isn't often mentioned) is that the fat-tailed dunnart is, for want of a better word, kinda basic. Things like the numbat (or the Tasmanian devil) are pretty weird for Aussie marsupials. They have derived a long way from the basic plan, which means that it might be even more difficult to figure out all the changes in their genomes. The fat-tailed dunnart would be easier - though still a monumental effort!
@@douglassrovinsky thank you for the insight on that problem, I didn't know that. So with that being said have the found anything on being able to complete the gene structure of the thylacine? or is that the imposible task on being able to clone one? From what this video says is yes. What's your take on it personally?
@@curtbradley5363 First, full disclosure: I am not a genomicist; that is not my area of expertise, haha. From what I understand, while the researchers involved have done a lot of work and made impressive gains, there's just not a lot of good-quality genetic material to work with, and what we do have is so fragmented and often non-overlapping that it makes it even more difficult. They would have to do something like the Jurassic Park "frog DNA" thing, where they simply insert a relative's DNA into the rather large gaps and hope for the best; I imagine it will be a trial and error thing for quite a while, and we'll never know exactly how close we are getting to a "real, high-fidelity" thylacine. Of course, recent studies have shown that the DNA that is NOT shared between relatives is what makes those species distinct (and ecologically meaningful), so any genetic material that we are missing which isn't shared between the thylacine and other dasyuromorphs because it is part of what made the thylacine a distinct species is just... gone. One other thing - what they are doing is not cloning. Cloning is exactly what it sounds like - you have one egg, and you make a copy of that. We have zero thylacine eggs. What the team is doing is more properly "engineering" a thylacine. They are taking what DNA we have, adding stuff to fill in the gaps, and then will incorporate that DNA into an emptied egg, which would be implanted into a surrogate mother.
You need to do time travel back in time, and take some puppy of thylacine or the Benjamin itself and come back with it in our time. Yàaaaaa it's possible 📺📺📺📺📺📺📺📺📺📺📺📺
Correct me if I'm wrong but animals that have been successfully cloned have had a bad track record of staying healthy and alive for very long. And those are non extinct animals. Imagine how much harder it's gonna be to clone an extinct animal. That's just the first challenge. Then they'd need to produce enough of them with diverse blood lines in order to even hope they could produce offspring naturally. I would love for them to be brought back but I don't think we're capable of replicating millions of years of evolution in a lab
Each failure is a learning experience and corrections will be made for each generation. The science may not have advanced enough at this point but science will advance and do things in the future that we cannot even imagine!
Why is everyone saying th3 next few decades??? I dont think alot of people understand how advanced alot of what we can do is. I think alot of this tech has been there for a while. But without enough financial backers to make it worth them doing, it hasnt come to light. I honestly believe with enough funding, they will decide they can make money out of it rather than losing money and they will make it happen. The issue there then becomes, at what point does it then become about financial gain amd less about the conservation and de-extinction? Do you start to cut corners? Do you start putting out half arsed copies that "look like a dog, walk like a dog, must be a dog", for example. And actually stay true to the ethics of why you started the process to begin with... only be very selective with what you choose to use as a potential de-extinction candidate IF its ethically correct, science is there and not just a copy but as true to the essense of WHAT that animal was
Except it isn’t. I forget which genetics lab is working on in, but they’re using the closest living relative as a surrogate mother along with a fully sequenced genome to clone it. I honestly have literally no clue what this guy is talking about when it comes to the Thylacene being so distant from other marsupials evolutionarily. That’s not necessarily untrue, but it hasn’t resulted in any major setbacks in the program thus far. We will bring back the Tasmanian Tiger.
Come on that specimen looks in good shape just need some time if Jurassic Park and World brought back the dinosaurs then we can bring back the Tasmanian Tiger
it's not going to be a thylacine, it will be a part thylacine. I kind of hope we can bring them back, but I think I more hope they can't. I would much prefer we stopped causing extinctions in the first place.
You can raise them in sanctuary where they are given small carcasses to hunt then work up through gradually bigger living prey then give them a much larger enclosure where they have to put in more work, breed them, make sure there’s always an excessive amount of prey then their young will be far more capable, reduce the concentration of prey as the next generation are maturing making it more difficult while they were taught how to operate by the parents then their young are released in the most optimal wilderness once they mature and further generations spread out from there
When Tasmania was colonised, they weren't endangered at the time, they were abundant, being the top predator on the island. However, the British brought their sheep, chickens and other livestock, and farmers started to come into conflict with the Thylacine. They blamed them for killing sheep mostly, the government declared them a pest and a bounty was put on them. Farmers then started to hunt them by trapping and shooting. Tasmanian Devils and Quolls were also added to the kill bounty and all the native predatory mammals started to crash in population. The severe loss in genetic diversity that resulted in this genocide of their species is also largely to blame for the 'DFTD' which is now threatening Tasmanian Devil's with extinction (because overhunting left the survivors with such small genetic diversity that a cancer can now jump between them). Quolls also suffered this, and to this day, some farmers will illegally kill them in secret. In simplest terms, people valued money and farming more than the existence of other species. A few sheep and chickens were lost, some farmers got angry and that apparently justified killing the entire species forever.
The farmers were told they were killing sheep ,they don't eat large prey ,,they did eat small mammals like possums , rats, mice , paddemelons ,wallaby , something about the jaws did not allow them to take large prey . so they were killed for nothing ,
..... Dominant species continues it's ignorance, hoping to undo our foolishness with a gene pool of one specimen. P.S. 'Hard Quiz' is the only free to air television I watch.
This video show us hall cruel is the "human beast"!! The good news is we are in the line to extinct too. We are drinking self-venon. Sorry, because my bad english. I am brazilian. But i nedeed spread my anger. All love us living in the same bubble. How many time for us? Are we the next in the cabinets museum collection??? 🤔😔🐆🌏🌎🌍🕊
Why do we obsess so much about that one specific species when so many different animals have gone extincts in the past decades? Bringing them back to life is useless if we can?t make sure we won't bring them back to exctinction within 10 years.
In 2003 they brought back an extinct goat. It lived for 7 minutes due to deformities. That was 20 years ago. Are we to believe science simply gave up? No, they are more than likely bringing back animals that are not correctly developing, but they wouldn't want the general public to know that they are failing over and over. Even more, they wouldn't want the public to know that they are creating life in mutant form, that quickly dies, or they keep in some lab zoo. But with the thylacine, there's still plenty of reason for hope that they still exist. Rather than trying to create a mutant version, they should spend their money looking for them.
Going by the old footage, it walked in an off-rhythm type of way, closer to a hyena than a dog, though it's from a completely different line of animals to either of those. If they can clone it back to existence simply by altering the DNA of modern-day mammals, one would think it would be the start of many more such ventures for other extinct species.... But realistically, if you brought it back, & put it back into the wild, what would it feed on? & would it wipe out other native species in order to satisfy it's appetite? Don't forget, back when the Thylacine was flourishing, there were many more native animals available for it to eat, but that isn't the case any more.....would we introduce a plague of rats for it to eat so it would leave our native species alone? There's too many issues about this venture to ever be confident about it becoming a success...
First, it’s possible there still are some in the wild. Second the prey species they ate is thriving, possibly too much. Third, the habitat is still there. So no problem.
Cant you just modify a kangaroo to produce thylasine breast milk and grow a test tube embryo clone and then latch it to the pouch? They literally made goats that produce spider silk milk.
Aprreciate how honest you Guys are, we need more people like y'all
Its really depressing that by the time the thylacine was granted protected status, it was already too late
What they didn't explain in this video is that yes, they can extract DNA from the little pup, but it is broken segments of DNA, not perfect, complete strands. However technology is advancing so quickly, that even gaps in the DNA can be patched with DNA from the closest living relative. Others have commented on this in this videos comments section. I'd love to see us start bringing animals back from extinction - the Dodo and many others - start undoing some of the damage we have done. Hope the human race can learn to tread more lightly on the planet, consume less, recycle more, produce less pollution, and start having a lot more regard for the environment, plants, animals we share our wonderful planet with.
P.S. I have 100 acres of land that I have set aside as a nature reserve and have taken decisive steps to ensure my family does the right things for the environment and our planet.
Sadly, there are no living relatives close enough. I too used to have this hope. But a species is so much more than its DNA. There is no creature alive that could teach it how to be a thylacine. 😢
I’ve been so fascinated by this animal ever since my Dad introduced me to the animal in 2009. I sincerely hope we see a cloned Thylacine within the next 20 years!!
It's not difficult if the DNA construction is put through a software algorithm handling calculations.
It will take 10 years frr 😮
I don't. What kind of a life would they live? Humans feel guilty, that's why they want to "bring back" thylacines. Protect and preserve the remaining endangered species
@@genkestrel7254 your not understanding this could also save the ones that are endangered as well there's some that most likely just might be gone recently cause we haven't been able to spot some endangered animals in a min they just haven't been placed as Instinct because of the hope that they are not gone already
@@joshuaguzman7725 They're gone. It's tragic but it's true.
As Dr Malcolm once said "Life uh finds a way".
Idk man, artificial wombs are looking more like a reality with each coming year. We could def bring a thylacine back that way
And a marsupial would likely be the first candidate for an artificial womb, since they only need to gestate for a couple of weeks, instead of months for placental mammals.
Nope it barely works for the animals that it was tested on. Biology is a bit more complicated than just “OHHH artificial womb, works for every mammal”
They do actually have artificial wooms now ,but they still in the beginning stages sort of thing. I saw a story about men using sex robots and artificial wooms because it's less hassle than dealing with a actual woman these days, and there's men who want to have children even if they haven't found the right partner just the same as how women use sperm donors and things . And especially with gay men these days and how allot of kids that think they are trans are getting doctors to sterilize them and take away there ability to reproduce in the future when they grow out of it and change their minds.but they've already been butcherd by doctors and uses as political pawns by politicians
That is not the biggest limiting factor here. Without close relatives to compare, our understanding of its genetics and development will be very limited. Colossal biosciences' proposed method of genetically modifying the Dunnart will require a huge number of simultaneous gene edits to get anything close to a thylacine. And then you have to consider all the non coding DNA that is essential for proper gene regulation and function. I am skeptical to say the least
@@jacobleese282 yes our technology and understanding of genetics isn’t there yet. Perhaps by the next 2 decades. Since cloning already existing mammals is already hassle.
Jokes on this guy, they are actually working on bringing them back, with the Fat Tailed Dunnart (Sminthopsis crassicaudata), the closest living relative, being the surrogate. They have the entire genomic sequence complete too from my understanding
Naaaahhhh... you've got it wrong. The Thylacines went into hiding. Why? Because they are in control... of everything! They are running the joint from behind the scenes. Thylacines are clever and cunning.
They are currently working on secret deals with the Chinese, Putin & Donald Trump... but that's a story for another day. ☢️ 🧤 🕶️
Literally 🤣🤣🤣
but they're small
@@normalperson5356 Marsupials are small when they're born, so that wouldn't really be an issue. Ever seen a newborn kangaroo? They're smaller than mice! I think the scientists got this covered haha, but it's fun to look into
@@imle9279 yeah, and I have a feeling it would be a surrogate only for the fetus, and the pup would be hand raised from the moment it was born. The dunnart may also be able to provide viable eggs to put the clone material into, since as far as I know we can't produce those artificially yet. But I haven't looked into the details of bringing back the thylacine so I'm not sure what their plan is exactly. I might do some reading later. The scientists working on this are still quite a long way off from what I understand. What's exciting is that they're looking at refining their "de-extinction" tech on animals that are functionally extinct, but not physically extinct. Basically, there are living animals, but too few of them to repopulate naturally. The plan is to use this tech to artificially create genetic diversity and prevent the genetic issues that can happen with extreme inbreeding, so that species that only have a dozen or fewer individuals left can potentially make a comeback.
We can always hope for a discovery to help bring them back.
Dude why play god we have no reason to they died for a reason. They just didn’t adapt well
@@Shawn64999 yeah adapt to bullets
@@willw9691 exactly
@@willw9691 why bring something back from the dead why not introduce endangered species to new places kinda like invasive species so they can adapt and thrive
@@Shawn64999 lol because that's also worked in the past your clearly not very knowledgeable on what that does to an environment so clear example introduced rabbits for hunting rabbits went rampant introduced foxes to control them now they are both out of control foxes killing native animals also introduced cane toads to control pest beetles in the sugar cane now they are out of control same for wild pigs & buffalo you don't introduce a species to a new habitat that cant be controlled by a native species and we don't have big predators apart from crocs that cant fully control them as they are water based predators & now here you also have issues with feral cats & dogs which are killing off vital native wildlife because people are incompetent at looking after animals & i am not saying thylacine will be able to control dogs, pigs & buffalo but they will be able control foxes rabbits & most likely cats which may cause them to adapt to killing off those species over native due to the abundance of them so please don't talk about things you have no clue about your the reason why people think its ok to introduce foreign animals without assessing the damage they will cause to an ecosystem please don't reply i wont respond to you an longer i have clearly shown why you shouldn't have a voice on this matter because you don't understand ecosystems
We only have lost so many types of mammals because we have had the most diverse group of mammals in the modern era.
Most other countries have had a huge amount of mammals that they killed off before keeping records of them.
I'm guessing feral cats and foxes have a very large role to play there too. I find it so frustrating that governments don't seem to want to do anything about it. My home suburb, home to a small nature reserve, was supposed to have had a fox cull a little while back, which was nixed due to animal welfare protestors. But these people failed to consider that although death for one fox may not be nice, one fox will kill dozens or hundreds of native animals (and pets - including my own birds) every year, and all those animals will die horrible deaths. Foxes don't kill kindly; they just rip live animals apart. Likewise, in the ACT adult cats must be desexed unless you have a permit, which helps reduce feral numbers. I don't understand why this kind of legislation cannot be enacted elsewhere.
What’s your excuse for gold fish and carp destroying your water ecosystems? And the several marsupial species that have bin killed? Who released and shipped the rabbits to hunt? Kangaroos? Couldn’t be the people’s fault oh no not like the whole country in 1800s was covered with convicted felons shipped from Europe 🤡 not like they failed a whole war with the emu’s which they would of gladly added to the extinction list and planned too
@@BigpapamoneymanMVPtypebeat If the Asians had arrived first things would be a lot worse.
@@tuathaigh-aa The arrival of Europeans doomed this place and many others
Never say never when it comes to science. I’m surprised he didn’t qualify that statement. Like we couldn’t just genetically engineer a womb that wouldn’t reject the Thylacine embryo.
The build up to that final question, to be disappointed…. Rip Thylacine
I found it odd they said no when there are others who say yes. I'm confused now
Thanks for bringing Gleeson!!
Our pleasure!
Would love to see a fully funded government campaign documentary trying to find out if they exist still using thermal imaging and latest technology.
Mammoth, Woolly Rhinoceros and Dodo definitely could be cloned.
Well that was super depressing. I’m not giving up on the Thylacine coming back , if it’s not already been done in some secret underground lab somewhere! 🐅
There's a small chance they never went extinct just been hiding really well from humans after we starting killing them like every other species if animal.
There’s a group of well-funded scientists who are working on bringing the thylasine back as we speak….
I wonder why they've taken so long to even try to do this 🤔 since the year 2000 they've been talking about this.
I'm so glad someone finally said the hard truth about whether thylacines could be brought back.
While the idea of bringing back the thylacine is really cool, programs that talk about it never lay out all the hurdles in the way.
First hurdle, you can't clone dead cells. If you don't have a sample taken from a living animal that was preserved, you're pretty much out of luck. Another option is to find the closest living relative of the extinct animal and modify the DNA within the egg and sperm cells of that species to replace the DNA that separates the two species to be the genes of the extinct animal, then have the close living relative act as a surrogate. This is how scientists have proposed bringing mammoths back. The closest living relative for the thylacine is the numbat. They last shared a common ancestor 38 million years ago.
Second hurdle to bringing back the thylacine is the lack of a surrogate. Marsupials only gestate for about 38 days, so even if an artificial uterus could be invented, that only covers the very first part of the development. Joeys below a certain age have never been successfully hand-raised, so not only would an artificial womb need to be invented, but so would an artificial pouch.
Third hurdle, milk. There are no marsupial species alive today that hold a similar ecological niche to what the thylacine did. Not only that, the composition of marsupial milk changes at every stage of a joey's development, which is one of the reasons why joeys below a certain age have never been hand raised. Finding the correct formula for every single growth stage would be a struggle, and likely result in many clones dying.
So you are a geneticist???
@@teleriferchnyfain I studied genetics for a few semesters in university, but I'm not a geneticist.
I'm from Australia and I wanted to be a wildlife rescuer when I was a teen, so I did research about raising joeys. Before the joey develops hair (often around 5 months old) it is simply impossible to keep them alive in human care. They are so fragile that only their mother's pouch can keep them alive.
A perfect example of this is that there was a program here in Australia (not sure if it's still ongoing) where joeys from a critically endangered wallaby were taken from their mothers a few days after their mouths stopped being fuzed to the mother's teat (yes, the mouths of joeys quite literally fuse to the teat for the first month or so of their life) and transferred to the pouch of surrogates of a different wallaby species. When that happened, the joeys of the surrogates had to be euthanised because marsupials only produce milk in the teats currently in use. If you want them to raise a different baby, one of their current ones has to disappear.
It's only a matter of time until our technology will get so much, that we'll be able to bring plenty of species back to life.
There are sightings ... lets hope there a few that stayed hidden from man only to find each other later ... that would be amazing!
all low res normal dog sightings ngl
I hope we can restore the Thylacine back to nature. We owe it to nature to bring them back after we removed them from nature. Despite the negative outlook of this scientist, we are doing things in science no one thought possible even 10 years ago. I am more optimistic than most we will succeed with the Thylacine and many others in the future!
Without watching yes it can.
Beautiful specimen, so tragic.
If scientists had a "no" for an answer we would still be living on trees chewing bananas.
Artifical wombs are possible, there is a guy that grew a chciken named rambo in a petri dish. It not only started off as a cell in the dish but also grew to a baby chick and thrived beyond.
He says no it can't be brought back but just recently one organization said yes in the next four to five years they will do it. I am guessing though if they do it it will be just a hybrid thylacine and not a 100% version. Kind of a replica but not the true version if you get my anology.
Thylacine both mainland and Tasmanian continue to exist with over 10 000 independent sightings.
Infact Tas gruberment hold its status as extant not extinct.
BTW although it's a wolf and also a marsupial so therefore the term pup is incorrect because it's pouched young are infact termed joey.
Many prints on photos and casts of I do have.
How do I upload a picture here?
Wolves and marsupials are completely unrelated animals. Thylacines are marsupials with a convergent evolution to look similar to canines superficially.
Weird though, marsupials in general seem great to bring back since they bareilly develop inside the womb.
" Bareilly " develop ?
or " barely " develop ?
Bareilly is a town in India 😆
@@shatnermohanty6678 👏
The fact they spend such little time developing in the womb actually makes marsupials the hardest to bring back. In the first few months in the pouch, the mother's milk basically changes from week to week, which is nearly impossible for humans to replicate. This is why if a marsupial joey is orphaned below a certain age, no matter the species, it will be euthanized because there is a 100% death rate for young joeys in foster care because we simply are incapable of providing what they need.
@@DragonFae16 You find a surrogate, after all plenty of animals can survive on other species milk, just drop it in a kangaroo. Not saying it will be the pinnacle of health or anything.
@@CMZneu A kangaroo could only be used as a surrogate for another macropod. And you'd have to use a kangaroo that has a joey of the same age as the orphaned one, remove the baby the kangaroo already has and discard it (which means euthanising it), and replace it with the orphaned joey. Kangaroos don't have twins and can only carry a single joey in their pouch at one time. And in fact, to boost the numbers of a critically endangered wallaby, that's exactly what is being done. Joeys that are about 2 months old are being taken from the pouches of their mothers to free the mother up to breed again. The joey is then flown to a zoo, where a captive population of common wallabies are. The chosen surrogate is sedated, her joey is removed and the foster joey is put in its place. The removed joey is then euthanized.
For a second I thought he was gonna say yes, because he took us so long of a pause
Is anyone still working on the Gastric Brooding Toad?
Modern science is cool!
With the advances being made in genetics research alone, it will be possible one day to achieve what was once thought impossible. Not so long ago the human genome was mapped for the very first time, a discovery that was unthinkable at the time. They are now theorising that babies will be born in the future in artificial wombs. The pace of technological advancement in the field of science regarding cloning in the last 30 years alone, has been astonishing. Whilst it may not be in our life times, the reality of cloning a thylacine is increasing with each new breakthrough in this field of research.
How can they store these Thylacine bodies so they don't decompose (rot)? If the use a preservative, wouldn't that affect any sample they wanted to obtain for the DNA (wouldn't the preservative be included)?
Good job humanity for wiping them out. Now I’ll never get to see the beautiful creature in real life.
As of October 25, 2023, scientists are working to bring the Tasmanian tiger as well as being close to bringing back the mommoth.also known as the thylacine, back from extinction by 2028. The last known thylacine died in captivity in 1936, and the species was declared extinct in 1986. However, no confirmed specimens have been found since its extinction, despite rumors of its survival.
The project involves several steps, including:
Constructing a genome: Create a detailed genome of the extinct animal
Comparing genomes: Compare the genome to that of the thylacine's closest living relative, the fat-tailed dunnart
Editing DNA: Edit the DNA of living cells from the dunnart to match the thylacine
Creating an embryo: Use gene editing technology on the tiger genome to create an embryo
Using stem cells: Use stem cell and reproductive techniques to turn the edited cell back into a living animal
According to Andrew Pask, who oversees the TIGRR Lab at the University of Melbourne, it could take his team until 2033 to create a thylacine-like cell, and it may be decades after that before the first Tasmanian tiger proxy is born
What a sad story.
Even if it could be done it would lack the opportunity to learn things like thylacine hunting behaviour (how much do we even know about that) which it would need to survive in the wild.
The saddest part is that it died out JUST AFTER it was given the protected title.
Wish they could bring them back one day
Sad situation that we allowed this magnificent animal to become extinct. It was too late when the government stopped paying generous bounties for killing them. I think there is a high probability that more existed in the wild, after the last died one died in captivity but they are gone now.
Apparently it’s closest realative is the Tasmanian devil so idk how that would work of bringing it back
what is the kind and color of the eyes of tazmanian tiger
How can they smile? The way we exterminate entire species from existence is utterly heartbreaking. The thylacine is just another lesson humanity fails to learn, over and over. 😔
No one alive today took part in their extermination so the use of the word 'We' is an insult and offensive to us all.
Maybe it was our grandparents generation, but there are 100s perhaps to 1000s of species that we are even aware of that have become extinct since we were born. So offended or not, we certainly fail to learn.
Nature and the changing climate has killed millions of times more than humans ever could yet you're not angry on nature and it's brutality. If nothing you should be happy we are trying to fix mistakes from the past since terms like conservationism of fauna are recent concepts humankind was never familiar or interesed with.
I too wish that humans were off the hook. I wish that the 30% of amazonian forests destroyed since 1973 was just part of a natural climate shift. If we continue to avoid responsibility as humanity, then we will stay on the current tragectory, and the remainder will be gone within 20 to 30 years.
Maybe you are okay with that and are content with this knowledge. Most of the world is. But personally, I'd argue we need an immediate and drastic change in practice. How we relate to our world and our delicate connection to the earth and its plants and animals... we need a massive paradigm shift.
In the short term there is an excellent musical artist called Thylacine
There was better one called Spoonbill, the albums Megafuana and Nest Egg make for a fine omelette.
Incrível parabens. Grande abraço Brasil
I love Brazil!!!🥺🥺
But what about the discovery of the fat tailed dunnart being the closest relative in August?
It's not. Dunnarts are equally "close" to the thylacine as any other dasyurid (like Tasmanian devils, quolls, or antechinuses) - or, for that matter, as "close" as the numbat is. All dasyurids share a common ancestor to the exclusion of the thylacine, which means that they are all equally close/distant to it - they are more closely related to each other than to the thylacine.
The numbat is in what is called a sister group to the dasyurids (that is, they are the other side of that branch - when a lineage splits into two groups - branches off - those two new branches or groups are called sister groups). This means that the numbat shares a common ancestor with the dasyurids... to the exclusion of the thylacine. And of course, this means that the numbat is equally close/distant to the thylacine as is the fat-tailed dunnart, or the Tasmanian devil. They are all not very closely related!
The thing with the fat-tailed dunnart is that it is well-known, easy house in a lab, and the researchers have been doing deep dives into its genome and developmental biology, so it's the Aussie mammal version of a lab rat. In other words - it's the Aussie marsupial who's "genomic puzzle" we know most about, so changing those puzzle pieces would be easier.
Another thing (which isn't often mentioned) is that the fat-tailed dunnart is, for want of a better word, kinda basic. Things like the numbat (or the Tasmanian devil) are pretty weird for Aussie marsupials. They have derived a long way from the basic plan, which means that it might be even more difficult to figure out all the changes in their genomes. The fat-tailed dunnart would be easier - though still a monumental effort!
@@douglassrovinsky thank you for the insight on that problem, I didn't know that. So with that being said have the found anything on being able to complete the gene structure of the thylacine? or is that the imposible task on being able to clone one? From what this video says is yes. What's your take on it personally?
@@curtbradley5363 First, full disclosure: I am not a genomicist; that is not my area of expertise, haha.
From what I understand, while the researchers involved have done a lot of work and made impressive gains, there's just not a lot of good-quality genetic material to work with, and what we do have is so fragmented and often non-overlapping that it makes it even more difficult. They would have to do something like the Jurassic Park "frog DNA" thing, where they simply insert a relative's DNA into the rather large gaps and hope for the best; I imagine it will be a trial and error thing for quite a while, and we'll never know exactly how close we are getting to a "real, high-fidelity" thylacine.
Of course, recent studies have shown that the DNA that is NOT shared between relatives is what makes those species distinct (and ecologically meaningful), so any genetic material that we are missing which isn't shared between the thylacine and other dasyuromorphs because it is part of what made the thylacine a distinct species is just... gone.
One other thing - what they are doing is not cloning. Cloning is exactly what it sounds like - you have one egg, and you make a copy of that. We have zero thylacine eggs. What the team is doing is more properly "engineering" a thylacine. They are taking what DNA we have, adding stuff to fill in the gaps, and then will incorporate that DNA into an emptied egg, which would be implanted into a surrogate mother.
We are completely responsible for there extinction so if we can bring them why not
the guy answered the question and said no.
How are they kept so well ???
Fosters in a jar mate
Some say "never say never".
It won’t be possible to bring them back 100% as they were if they’re able to do it at all I doubt it would barley be close to the real thing
If only I have the know-how and the resources, I would have cloned my departed daughter long ago😔
Well they are bringing them back
😂😂😂Why would he say no? It’s actually being done!!!!!!
You need to do time travel back in time, and take some puppy of thylacine or the Benjamin itself and come back with it in our time. Yàaaaaa it's possible
📺📺📺📺📺📺📺📺📺📺📺📺
If time travel were possible, we'd already know. It isn't.
If time travel were possible, we'd already know. It isn't.
Possibly......if it ever does it will me Melbourne research and work that makes it happen.
Go the Vics! ✌️
didnt they find a literal thylacine pelt?
are you bringing the thylacine back or are you making a mouse looks like a thylacine?
I want to see a Thylacine sized Fat tailed Dunnart.
Papa New Guinea
4:02 then play say's no .
Why would someone put a baby in a glass 😢
I think it's, NO!
What would be the point of all this cloning? Clones are sterile?
No they aren’t? There’s no reason why a cloned animal with all the regular biological functions of the animal it was cloned from would be sterile.
Except most first generation clones are decidedly less than fertile and have much lower over all vitality than the host organism.
@@tjw4947 But still not infertile, and most multicellular organisms that have been cloned still have the capacity to have offspring
Correct me if I'm wrong but animals that have been successfully cloned have had a bad track record of staying healthy and alive for very long. And those are non extinct animals. Imagine how much harder it's gonna be to clone an extinct animal. That's just the first challenge. Then they'd need to produce enough of them with diverse blood lines in order to even hope they could produce offspring naturally. I would love for them to be brought back but I don't think we're capable of replicating millions of years of evolution in a lab
They found that all known cheetahs are closely related family members. There is little genetic diversity, yet they still survive.
Each failure is a learning experience and corrections will be made for each generation. The science may not have advanced enough at this point but science will advance and do things in the future that we cannot even imagine!
Why is everyone saying th3 next few decades??? I dont think alot of people understand how advanced alot of what we can do is. I think alot of this tech has been there for a while. But without enough financial backers to make it worth them doing, it hasnt come to light. I honestly believe with enough funding, they will decide they can make money out of it rather than losing money and they will make it happen. The issue there then becomes, at what point does it then become about financial gain amd less about the conservation and de-extinction? Do you start to cut corners? Do you start putting out half arsed copies that "look like a dog, walk like a dog, must be a dog", for example. And actually stay true to the ethics of why you started the process to begin with... only be very selective with what you choose to use as a potential de-extinction candidate IF its ethically correct, science is there and not just a copy but as true to the essense of WHAT that animal was
If they do get the genes how are they going to gestate it? Artificial wombs are not there yet.
Clearly tom gleeson is a clone of bill burr....
Sad to hear that the answer is no.
Except it isn’t. I forget which genetics lab is working on in, but they’re using the closest living relative as a surrogate mother along with a fully sequenced genome to clone it. I honestly have literally no clue what this guy is talking about when it comes to the Thylacene being so distant from other marsupials evolutionarily. That’s not necessarily untrue, but it hasn’t resulted in any major setbacks in the program thus far. We will bring back the Tasmanian Tiger.
@@diegodollarhide6663 I hope so!
@@rocket5557 I too am excited to see their return. Such a shame they were killed in the first place
That dont fase me ,when i seen the yowie or big foot.??👹
Come on that specimen looks in good shape just need some time if Jurassic Park and World brought back the dinosaurs then we can bring back the Tasmanian Tiger
when i saw that kind of places, i just feel the human cruelty
I don't think they are extict
it's not going to be a thylacine, it will be a part thylacine. I kind of hope we can bring them back, but I think I more hope they can't. I would much prefer we stopped causing extinctions in the first place.
There are many sightings in Papua New Guinea. They might have survived there
brought back to live on an estate fully locked in because it will be worth a fortune.
What about the idea of making a robot mother to clone one? I really doubt that this could be done. I just thought of this stupid idea.
Thylacines and aboriginal people. Those dang van demons, ay.
Even if they're brought back, how are they taught to fend for themselves. How are they taught to hunt?
You can raise them in sanctuary where they are given small carcasses to hunt then work up through gradually bigger living prey then give them a much larger enclosure where they have to put in more work, breed them, make sure there’s always an excessive amount of prey then their young will be far more capable, reduce the concentration of prey as the next generation are maturing making it more difficult while they were taught how to operate by the parents then their young are released in the most optimal wilderness once they mature and further generations spread out from there
Natural instincts
Bring mammoth 😢
As always happen Human got new discoverd something and destroy it after
tom gleeson acting normal for once and not taking the piss. Lol
This is so sad :(
Why they killed these endangered Animals???
Sport hunting...Aka, idiocy.
When Tasmania was colonised, they weren't endangered at the time, they were abundant, being the top predator on the island. However, the British brought their sheep, chickens and other livestock, and farmers started to come into conflict with the Thylacine. They blamed them for killing sheep mostly, the government declared them a pest and a bounty was put on them. Farmers then started to hunt them by trapping and shooting. Tasmanian Devils and Quolls were also added to the kill bounty and all the native predatory mammals started to crash in population. The severe loss in genetic diversity that resulted in this genocide of their species is also largely to blame for the 'DFTD' which is now threatening Tasmanian Devil's with extinction (because overhunting left the survivors with such small genetic diversity that a cancer can now jump between them). Quolls also suffered this, and to this day, some farmers will illegally kill them in secret.
In simplest terms, people valued money and farming more than the existence of other species. A few sheep and chickens were lost, some farmers got angry and that apparently justified killing the entire species forever.
Because they didn't know they were Endangered 🤦
The farmers were told they were killing sheep ,they don't eat large prey ,,they did eat small mammals like possums , rats, mice , paddemelons ,wallaby , something about the jaws did not allow them to take large prey . so they were killed for nothing ,
They killed sheep. People used to put bounties on their head, and didn't realize that they were essential to the environment until it was too late.
starting to lose hope, i just wanna see a thylacine.
This is BS!
..... Dominant species continues it's ignorance,
hoping to undo our foolishness with a gene pool of one specimen.
P.S. 'Hard Quiz' is the only free to air television I watch.
true and such a shame on us
This video show us hall cruel is the "human beast"!! The good news is we are in the line to extinct too. We are drinking self-venon. Sorry, because my bad english. I am brazilian. But i nedeed spread my anger. All love us living in the same bubble. How many time for us? Are we the next in the cabinets museum collection??? 🤔😔🐆🌏🌎🌍🕊
😪
Should be hiding somewhere in the Niugini highlands
We’ve been looking in the wrong place, they’re out there in PNG.
Why do we obsess so much about that one specific species when so many different animals have gone extincts in the past decades? Bringing them back to life is useless if we can?t make sure we won't bring them back to exctinction within 10 years.
In 2003 they brought back an extinct goat. It lived for 7 minutes due to deformities. That was 20 years ago. Are we to believe science simply gave up? No, they are more than likely bringing back animals that are not correctly developing, but they wouldn't want the general public to know that they are failing over and over. Even more, they wouldn't want the public to know that they are creating life in mutant form, that quickly dies, or they keep in some lab zoo. But with the thylacine, there's still plenty of reason for hope that they still exist. Rather than trying to create a mutant version, they should spend their money looking for them.
Yes. An Ibex. Infections are the problem but that will be solved.
Can't stand Tom Gleeson from Gunnedah
Never say never.
What about Joe Biden? Is someone working on bringing him back? I hope not.
Going by the old footage, it walked in an off-rhythm type of way, closer to a hyena than a dog, though it's from a completely different line of animals to either of those.
If they can clone it back to existence simply by altering the DNA of modern-day mammals, one would think it would be the start of many more such ventures for other extinct species....
But realistically, if you brought it back, & put it back into the wild, what would it feed on? & would it wipe out other native species in order to satisfy it's appetite?
Don't forget, back when the Thylacine was flourishing, there were many more native animals available for it to eat, but that isn't the case any more.....would we introduce a plague of rats for it to eat so it would leave our native species alone?
There's too many issues about this venture to ever be confident about it becoming a success...
There are hundreds of thousands of roadkill every year in australia and tasmania. For sure the thylacine can prosper still
First, it’s possible there still are some in the wild. Second the prey species they ate is thriving, possibly too much. Third, the habitat is still there. So no problem.
The world needs a Thylacine.
Cant you just modify a kangaroo to produce thylasine breast milk and grow a test tube embryo clone and then latch it to the pouch?
They literally made goats that produce spider silk milk.
Leaving likes at 666
I don't want them to come back because they will be exploited like everything else