I started autophagy and started eating healthy 3 months ago. Now I am no longer diabetic, no high blood pressure, and cancer-free. Also, lost weight (A total plus). My skin improved tremendously
Can you tell me what cancer you overcome? I'm doing what you are doing, I have pancreatic cancer. Diabetes too. I'm starting to feel like those who cannot tolerate the poison of sugar have to reach autophagy to heal cellular damage. Thank you for sharing.
@@debracottrill7989 liver cancer. I eliminated all carbs and did keto diet and did this. I was at stage 4 cancer when I started. Within 3 months, I was 40% cancer free
Dr. Ohsumi, a lot of people in the world now benefits good health freely because of your 30yrs study of Autophagy. Thank you very much sir. God bless you more!
Yes, born 1945 world war ii was over. In japan really hard time to get food. Mom got TB and she stayed in bed for a long time - really hard time to get enough food. That time all people were poor in Japan. Everyone overcome those problems. Yes, i know about Noble prize. I was not so healthy boy, dream was to become a scientist. My father was working at the University. Not so far from University. I wanted to be a scientist. One point, I didn’t want to be in a competitive field. When i started in vacole not many people were working on that subject. That was very good for me. I wasn’t confident and not many people were working in that field. I might not do it now as many people are working on autophagy. Okay, for me i want to understand how cell is dynamic. Actually life is adjustable ..... not so many people interested in degradation. lots of people work on ... not so many on the degradation. Degradation is important. The function of the degradation process. For me, degradation must be equally important. Function of the degradation process. Almost every function of the body has degradation . Important for me autophagy so important for the cell. We only know 30% understanding of autophagy and been working on it 30 years. Autophagy is not so long history. That’s my feeling on autophagy I always showed the slide how the body makes 200 grams protein a day. But we take 70-80 grams from food. Two figures tells us that new protein comes .... important to understand. So ya, for me surprising fact all protein is replaced every two or 3 months. All protein in body replaced. Life is maintained. These days, many many casts or company or newspapers sold many people ... already 3-4 years situation happen for me. So noisy. Hard to say, several people say you will have this in 2-3 years. I not think about that. Took 3 years to publish paper. I wanted to publish 2 papers but not a good way. Took a long time for me. Something new , take that long. Probably as i said autophagy so basic a function of the cell to understand the cell or our body. Autophagy must be involved in many things. Autophagy is involved in so mnay things. Reason my work autophagy in yeast cells.... dissect yeast .... most important cell first genes. Understand autophagy. Autophagy genes in plants and showed ... not so easy to analyze... still difficult... ag genes... research you can analyze autophagy by ag genes. Completely changed research all over the world. Everyone started studying autophagy. Finding the discovery of the ag genes most important. Sorry. Hum. Still okay. Many people interested in autophagy for disease and health problems. I think it is quite reasonable. Degredation is important. Cells should be maintained clean. Very important for our cells. Autophagy one function is recycle cell... eliminates harmful material in the cell. Those kind must be very important to cells and diseases. Still don’t have special medicine to regulate autophagy but might be New science. Probably not familiar. Hum. Okay. For me, so hum. What should I say. Yeah, of course we have many serious problems. Each people have their own serious problems... important... learn a lot how our body working . How whole body is organized. Yeast cell is simple one cell. Still we have many problems to solve. Every cell has a different function. Important to know how cell communication with each other. Every cell has its autophagy function. Own cell autophagy might be the problem. How different cells have different function. Important....some simple... autophagy might not help some people’s health. We need more work on autophagy how it’s regulation in every cell in our body. Okay. I am already quite old. I don’t know how long i will continue my work. I want to have a really good measuring.... what is degradation and how much extent autophagy does in that cell. I want to have biochemistry to just use yeast cell. Improve our knowledge of how it works in Our body *********************I missed a little but maybe it will help you understand better what he is saying ************He discovered at least 15 genes involved with controlling autophagy in the yeast cell.
John Hans This is no where a brilliant discovery, Indians defined and proved this millions of years ago and they are practicing this from then owards...
biological Health you know what happened when a person call an intelligent one " idiot"? It happens that we all find out he's a totally brainless human :)
Such a beautiful position he takes throughout the interview, that of a Nobel prize winner but always open to learn and have his position from studies and papers challenged. What a truly humble and a beautiful human being and a scientist is Mr. Yoshinori Ohsumi ❤️
I watched this twice, second time with closed captioning, which was a huge help. This was a very important interview from a great man, and I wanted to understand and soak in everything he said. His quote at the end says it all about him and his accomplishments, something we can all learn from if we want to achieve any level of greatness in our lives. After achieving the highest honor in his field, this is his response, that all that has done was to open so many more questions. Words to live by. What an incredible man. For his achievements he is very humble because his focus is on his work, not himself. This was much more than an interview on the authority on autophagy. This was what greatness truly is, something we can all learn from. Thank you so very much for this interview and video.
@@RS-dq9pn that's not true. Asians I've seen generally don't age well. Their skin is beautiful at a young age but after 50 it looks very old. This man looks 20 years younger than his actual age
What an honor to hear Dr. Ohsumi speak about his life’s work and what drove his research! So gracious and thoughtful in his answers. Thank you Naomi! ❤️
Learning about ketones and autophagy just recently has totally changed my health. I am inspired by his work and I thank him and you for presenting him to me! Thanks, Naomi!
what a gracious gentleman. He answered your well thought out questions in ways we could all understand. The most important thing I took out of this, is not to worry about fasting destroying our muscles, as our body will make the protein it needs to maintain them through Autophagy by using up all those degrading cells!
Yes, I'm sure the body is saying, Its about time I have some energy from fasting to clean house from years of garbage (degraded cells etc) collecting. How good does it feel when we clean our home spotless!
Well, provided your body has enough fat to burn and is mobilizing it in a rate sufficient for not cutting into useful protein. Meaning you get into ketosis, and it is just a matter of time if all you're consuming is water and perhaps an autophagy activator like coffee (just an example, and one shouldn't drown oneself in coffee to fast successfully ^^). In anorexics for instance it's observed that even the heart is broken down for protein for survival! But that's from starvation, and not healthy fasting with proper healthy refeeding. So if you get into a proper fasted state, with sufficient mobilized body-fat, minimal amounts of useful protein is broken down. There are ketogenic researchers who's observed that protein is being burned regardlessly if your body is mobilizing sufficient fat, and concludes that water-fasting is not so good for maintaining muscle, and are more in favor of maintaining a ketogenic diet with intermittent fasting. But that's rather simplistic, and I trust that the body is maintaining the useful tissues when there's less useful stuff to break down. And now there's emerging things like the fasting mimicking diet, that's been shown to be pretty much equally effective and in some cases more effective than water fasting, and glucosamine has been observed to activate autophagy more than water fasting as well. But these studies are in mice, and they aren't really suited to ketosis or water fasting like people. As they will lose a huge amount of their body-mass in just a few days, whereas humans can much more effectively maintain their body-composition during water-fasting. So this is a very exciting field! though I'm not even in it, I'm just reading up on the latest stuff on the net ^^ And practicing it with great results in health and well-being. And I think extended fasting is great for mental health as well!
Woooow Naomi! I am so grateful for this interview! It was really touching how this inspiring person keeps researching and explaining with so much humbleness! You did a very good job giving him the time to find the right words to express himself. So precious and so respectful! You are a very special person, Naomi! Many many blessings to you and your loved ones from Germany 🩵🩵🩵🩵🩵🩵🩵
What an amazing man! His dedication to this complicated area of cell life and its impact is somewhat mind boggling. Like he said his work over these many years has uncovered a small part of understanding the degradation process, and now so many more questions have arisen. He is so humble. I loved watching him formulate his answers. What an amazing mind! Thank you so much for sharing this interview.
I think he articulated everything quite precisely. However, I lived in Japan and have an ear for Japanglish, which makes the auditory processing easier.
So refreshing to see such a humble genius who is worthy of praise. You can see he dont feel he deserves all this attention he dont seem to want it. Which is so amazing bc so many who have no talent no brains recieve so much attention and they eat it to right up and are the opposite not humble.
IT IS A FACT THAT EXAMPLES WORK MORE UPON THE MIND THAN PRECEPTS.I HAVE BEEN FASTING SINCE I WAS YOUNG (A MONTH EVERY YEAR) NOW THE THING IS I AM ALMOST 70 AT THE MOMENT AND STILL I FEEL (BOTH MENTALLY AND PHYSICALLY I AM STILL 25!!!)
but ramadhan fasting is less than 16 hours...not enough for autophagy infact muslim have the same health issues compared to people who doesnt take fasting in ramadhan.....people should fast not only on ramadhan but on daily basis every month...ramadhan fasting is not special in term of health compared to ketogenic fasting backed up by science
What a lovely gentle man. Glad I started being involved in fasting and autophagy about 5 years ago as well as time restricted eating. Problem is the people who would benefit the most from improving autophagy consider the whole field esoteric and for the fanatical few
Thank you for this interview with this Giant, the shoulders on which all those in the “autophagy arena” stand. What an incredible human. Thank you, Sir. 🙏🏽
"We only understand about 30% of the science and working of autophagy", he says. !! That needs to be on a big banner flying across all the vids claiming ANYTHING about autophagy. Enjoyed this video very much.
The rest of us can learn a LOT from that. Too many yahoos arond. Majority of them are young too, just because their parents told them they are better than anyone else. This man has devoted his career to his science and it took him decades to come to this point. Herein is the wisdom only the truly wise who are willing to listen can use.
Julietzki Zara This is no where a brilliant discovery, Indians defined and proved this millions of years ago and they are practicing this from then owards...
Two thousand five hundred years ago, the Buddha, experimented with different life styles. Born into royality, he led a luxurious life, but was disillusoned by the suffering of the poor as well as that of the wealthy who suffered because of over indulgence. He thus advcated the middle path, refraining fom starvation , as well as from gluttony, by eating once a day before noon. A pratice that is followed by countless buddhist monks , at the present.
So interesting! I am so fond of this gentle man:) I had no idea that most of the protein that our body uses every day is from autophagy, not from our ingested protein.
Please note: Dr Ohsumi is a scientist. His work and that of his team that won a Nobel prize, was their identification of genes which made it easier to study autophagy. As of this interview he stated they understood about 30% of autophagy IN YEAST (30 years of work). Mammalian cells (that’s us) are more complex. In this video there was no mention of fasting or a specific diet. No mention was made of any specific way to enhance human autophagy or even if that was desirable. There was mention that in future, it may be possible to develop medication that would control the autophagy processes. Research continues….
This is how you realize how your BODY IS MORE POWERFUL than you can imagine (not only your Thoughts!)! There is an enzyme in our body that can minimize aging, and is harnessed through the correct meditation and energy exercise (yoga? qi gong?...who knows!). We will wait for the next nobel prize winner to discover this! ;)
This is an honor he's a genius I can listen to him for hours I'm so grateful to God for this humble genius man and for Finding this video thank you thank you
In India, we have been following fasting methods for thousands of years... But because of religious reasons. In our ancient religious books/ literature/ Vedas, the long water fastings have been given lots of importance. Every where it is mentioned that in a healthy body lives a healthy mind. So when you sit for meditation ( which is way to feel/ meet/ sense the GOD), first you cure/ purifie your body with fasting, so that you could sit easily and concentrate / meditate. I think they entangled fasting with religion so that people would follow it for the sake of GOD if not otherwise.
Agree. Religion, when used wisely by very ethical, honorable, discerning leaders, is ultimately beneficial for its practitioners. Monks and nuns have also practiced fasting and meditation in the form of prayers & vigils. What Dr Osumi has learned and expounded on is the scientific basis for these practices. Oftentimes our "modern" minds scoff at something we don't understand and discard traditional knowledge as ancient balderdash until we see the validity of it with our own eyes.
Totally agree. The ancient epic Mahabharata say: it was by fasts the deities have succeeded in becoming denizens of heaven. It is by fast that the Rish have attained high success. Chyavana, Jamadagni, Vasishtha, Gautama and Brigu - all these great Rishis endued with the virtue of forgiveness have attained to heaven through observance of fasts. In former days Angirasa declared so unto the great Rishis. The man who teaches another the merit of fasts has never to suffer any kind of misery. The one who daily reads this ordinances (about fast), or hears them becomes freed from sins of every kind
When I look closely at the radiance of this man, I almost forget that aging is something negative. But my question is: To what extent could autophagy support or eliminate one of the seven points that make up the Aubrey de Gray theory (intracellurar junk)? Does autophagy also clean the collected garbage outside the cell? This last question seems to me to be of central importance for the appearance of a human being (speaks beauty of the skin).
Thank you Naomi 😍🌹for sharing this video with a humble but great person for his wonderful work on autophagy. 2 Questions: (1) How many hours before the process of autophagy takes place ? Would a 16/8 intermittent fasting protocol help or do we need a longer period (2) Dr Ohsumi’s comment about protein: does it mean that we should not consume too much protein as it might affect the autophagy process ?
21:12: Aww, I think he would have been quite excited to hear more about it, and would probably have some interesting comments on it, if you could have gone into it a bit more. But keeping it on a broad level was probably the best choice. As it's an interview, and not a "reviewing science of autophagy with the initiator of the research on it" -- though that's something that'd be really exciting for me in any case! ^^ 26:45: It's amazing and great that he's still excited to do more of the basic and very essential research of improving the methodology of studying autophagy! Thank you Naomi for conducting this lovely interview! He's such a patient and humble man!
I read a lot of comments about how much of a genius he is, and while that may be true I’m more interested in what people are taking away from his work in practical day to day applications. 1. That protein synthesis comes from autophagy of our own protein cells. Therefore we must replace that protein through diet, not just for muscle growth but for all the bodies processes that require protein. 2. The way our body synthesizes protein is also the reason why we lose muscle mass if we don’t get enough protein in our diet, as well as poor health due to the organs cell requirements.
Dear ms whittel... You made me understand why a Belgian man got the title of viscount in 1989. It was Christian de Duve. Recipiant of the Nobel Price of physiology in the seventies for his work on the lysosome and coming up with the term autophagy. Thx for that.
Dear Naomi, I stumbled over this video one year too late but what a pleasure to see it. More than the content and the interviewee (who is very distinguished of course), the clip is enriched by your interviewing style, personal charm and demeanor. Saying, just in case you find this message in the bottle :-). I am reading your blog now.
This is just tip of the ice berg.This fasting was a weekly practice in siddha and ayurveda.There will be shockwaves in this world when modern science acknowledges and properly researches about life force energy and bramacharya( advanced version of no fap)
@@naomiwhittel so, is he saying that we have a long way to know exactly the mechanism by which some or all cells behave or degrade. That is, will long term fasting necessarily protect all or some cells or does it really depend on which part of the body the cells are located.
Mehtab Shams This is no where a brilliant discovery, Indians defined and proved this millions of years ago and they are practicing this from then owards...
Brilliant!! Since it is a rare interview, we really would have liked to understand his words. Good English, just not too understandable. Thank you for adding subtitles soon.
This brilliant pioneer exudes such self-evasive humility - so typical in Japanese culture - that he seems to be uncomfortably embarrassed by effusive comments from the interviewer - so typical in American culture.
Maria Butler Yes, he’s very soft spoken and his English is slightly limited, but if you’re using a laptop or desktop, at the bottom right side there’s a CC button for subtitles, and if you’re on a mobile device tap on the 3 dots at the top right of the screen and select captions there.
I started autophagy and started eating healthy 3 months ago. Now I am no longer diabetic, no high blood pressure, and cancer-free. Also, lost weight (A total plus). My skin improved tremendously
Can you tell me what cancer you overcome? I'm doing what you are doing, I have pancreatic cancer. Diabetes too. I'm starting to feel like those who cannot tolerate the poison of sugar have to reach autophagy to heal cellular damage. Thank you for sharing.
@@debracottrill7989 liver cancer. I eliminated all carbs and did keto diet and did this. I was at stage 4 cancer when I started. Within 3 months, I was 40% cancer free
@@debracottrill7989 now its all gone
Are you fasting ?
can you share how is your condition now
Dr. Ohsumi, a lot of people in the world now benefits good health freely because of your 30yrs study of Autophagy. Thank you very much sir. God bless you more!
Yes, born 1945 world war ii was over. In japan really hard time to get food. Mom got TB and she stayed in bed for a long time - really hard time to get enough food. That time all people were poor in Japan. Everyone overcome those problems.
Yes, i know about Noble prize. I was not so healthy boy, dream was to become a scientist. My father was working at the University. Not so far from University. I wanted to be a scientist.
One point, I didn’t want to be in a competitive field. When i started in vacole not many people were working on that subject. That was very good for me. I wasn’t confident and not many people were working in that field. I might not do it now as many people are working on autophagy.
Okay, for me i want to understand how cell is dynamic. Actually life is adjustable ..... not so many people interested in degradation. lots of people work on ... not so many on the degradation. Degradation is important. The function of the degradation process. For me, degradation must be equally important. Function of the degradation process. Almost every function of the body has degradation . Important for me autophagy so important for the cell. We only know 30% understanding of autophagy and been working on it 30 years. Autophagy is not so long history. That’s my feeling on autophagy
I always showed the slide how the body makes 200 grams protein a day. But we take 70-80 grams from food. Two figures tells us that new protein comes .... important to understand.
So ya, for me surprising fact all protein is replaced every two or 3 months. All protein in body replaced. Life is maintained.
These days, many many casts or company or newspapers sold many people ... already 3-4 years situation happen for me. So noisy.
Hard to say, several people say you will have this in 2-3 years. I not think about that.
Took 3 years to publish paper. I wanted to publish 2 papers but not a good way. Took a long time for me. Something new , take that long.
Probably as i said autophagy so basic a function of the cell to understand the cell or our body. Autophagy must be involved in many things. Autophagy is involved in so mnay things. Reason my work autophagy in yeast cells.... dissect yeast .... most important cell first genes. Understand autophagy. Autophagy genes in plants and showed ...
not so easy to analyze... still difficult... ag genes... research you can analyze autophagy by ag genes. Completely changed research all over the world. Everyone started studying autophagy. Finding the discovery of the ag genes most important.
Sorry. Hum. Still okay. Many people interested in autophagy for disease and health problems. I think it is quite reasonable. Degredation is important. Cells should be maintained clean. Very important for our cells. Autophagy one function is recycle cell... eliminates harmful material in the cell. Those kind must be very important to cells and diseases. Still don’t have special medicine to regulate autophagy but might be New science.
Probably not familiar.
Hum. Okay. For me, so hum. What should I say. Yeah, of course we have many serious problems. Each people have their own serious problems... important... learn a lot how our body working . How whole body is organized. Yeast cell is simple one cell. Still we have many problems to solve. Every cell has a different function. Important to know how cell communication with each other. Every cell has its autophagy function. Own cell autophagy might be the problem. How different cells have different function. Important....some simple... autophagy might not help some people’s health. We need more work on autophagy how it’s regulation in every cell in our body.
Okay. I am already quite old. I don’t know how long i will continue my work. I want to have a really good measuring.... what is degradation and how much extent autophagy does in that cell. I want to have biochemistry to just use yeast cell. Improve our knowledge of how it works in Our body
*********************I missed a little but maybe it will help you understand better what he is saying ************He discovered at least 15 genes involved with controlling autophagy in the yeast cell.
Thank you!
Thank you for your time and patience ✨
Thankyou!
Thank you much!
Thank you😊
He's a humble genius and represents the best part of what it means to be a human. That's what I have to say about Mr. Ohsumi.
John Hans This is no where a brilliant discovery, Indians defined and proved this millions of years ago and they are practicing this from then owards...
He is an idiot
@@tellfacts9387 : What he has done is proven the scientific basis for it.
biological Health you know what happened when a person call an intelligent one " idiot"? It happens that we all find out he's a totally brainless human :)
Dpp)ll)ll)lllf
Such a beautiful position he takes throughout the interview, that of a Nobel prize winner but always open to learn and have his position from studies and papers challenged. What a truly humble and a beautiful human being and a scientist is Mr. Yoshinori Ohsumi ❤️
Agreed
I watched this twice, second time with closed captioning, which was a huge help. This was a very important interview from a great man, and I wanted to understand and soak in everything he said.
His quote at the end says it all about him and his accomplishments, something we can all learn from if we want to achieve any level of greatness in our lives. After achieving the highest honor in his field, this is his response, that all that has done was to open so many more questions. Words to live by. What an incredible man. For his achievements he is very humble because his focus is on his work, not himself. This was much more than an interview on the authority on autophagy. This was what greatness truly is, something we can all learn from. Thank you so very much for this interview and video.
Unfortunately I couldn't find closed captions for this video.
Great achievement! Help all people. Will be the future
He is in his 70s and yet he looks young and mentally alert. His skin has a glow of a young person. That is so awesome!
You are totally right. And i noticed the same thing in Doctors who support Autophagy and live by example.
It works
Genetics has a lot to do with it modt asians look younger have great skin
he is in 70s?? wow
@@RS-dq9pn that's not true. Asians I've seen generally don't age well. Their skin is beautiful at a young age but after 50 it looks very old. This man looks 20 years younger than his actual age
Are you high
Thank you dr Yoshi ....
We were blessed so much.
It's a privilege to listen to him in one to one. He is a great achiever still humble. Thanx for organising it....
The greatest amongst us are the most humble.🙏
What an honor to hear Dr. Ohsumi speak about his life’s work and what drove his research! So gracious and thoughtful in his answers. Thank you Naomi! ❤️
Learning about ketones and autophagy just recently has totally changed my health. I am inspired by his work and I thank him and you for presenting him to me! Thanks, Naomi!
what a gracious gentleman. He answered your well thought out questions in ways we could all understand. The most important thing I took out of this, is not to worry about fasting destroying our muscles, as our body will make the protein it needs to maintain them through Autophagy by using up all those degrading cells!
Yes, I'm sure the body is saying, Its about time I have some energy from fasting to clean house from years of garbage (degraded cells etc) collecting. How good does it feel when we clean our home spotless!
Did he really answer the questions at all?
Thank you for that
Well, provided your body has enough fat to burn and is mobilizing it in a rate sufficient for not cutting into useful protein. Meaning you get into ketosis, and it is just a matter of time if all you're consuming is water and perhaps an autophagy activator like coffee (just an example, and one shouldn't drown oneself in coffee to fast successfully ^^).
In anorexics for instance it's observed that even the heart is broken down for protein for survival! But that's from starvation, and not healthy fasting with proper healthy refeeding. So if you get into a proper fasted state, with sufficient mobilized body-fat, minimal amounts of useful protein is broken down.
There are ketogenic researchers who's observed that protein is being burned regardlessly if your body is mobilizing sufficient fat, and concludes that water-fasting is not so good for maintaining muscle, and are more in favor of maintaining a ketogenic diet with intermittent fasting. But that's rather simplistic, and I trust that the body is maintaining the useful tissues when there's less useful stuff to break down.
And now there's emerging things like the fasting mimicking diet, that's been shown to be pretty much equally effective and in some cases more effective than water fasting, and glucosamine has been observed to activate autophagy more than water fasting as well. But these studies are in mice, and they aren't really suited to ketosis or water fasting like people. As they will lose a huge amount of their body-mass in just a few days, whereas humans can much more effectively maintain their body-composition during water-fasting.
So this is a very exciting field! though I'm not even in it, I'm just reading up on the latest stuff on the net ^^
And practicing it with great results in health and well-being. And I think extended fasting is great for mental health as well!
Well said Sylvia! Thank you.
Woooow Naomi! I am so grateful for this interview! It was really touching how this inspiring person keeps researching and explaining with so much humbleness! You did a very good job giving him the time to find the right words to express himself. So precious and so respectful! You are a very special person, Naomi! Many many blessings to you and your loved ones from Germany 🩵🩵🩵🩵🩵🩵🩵
Brilliant discovery ! Was terrified to go on fast because of prediabetes. Now I’m 36 hrs fasting and on my way to cleaning out the garbage cells.
Jk Melnyk how r u feeling tell about ur experience on 36 hours fasting
Excellent. I have done 5 days fasting with water and minerals only. Day 3 feels almost magical. I'm just beginning another fast today
Do you drink liquids during this fasting of 36 hours
Dr. Yoshinori Ohsumi rocks!
Love, love his contributions to the body of human knowledge.....
What an amazing man! His dedication to this complicated area of cell life and its impact is somewhat mind boggling.
Like he said his work over these many years has uncovered a small part of understanding the degradation process,
and now so many more questions have arisen. He is so humble. I loved watching him formulate his answers.
What an amazing mind! Thank you so much for sharing this interview.
Kind of wish the interview was in his native language and we had subtitles so he could articulate what he is saying better.
The subtitles could also just be added to this same video...
I think he articulated everything quite precisely. However, I lived in Japan and have an ear for Japanglish, which makes the auditory processing easier.
Yes. Me too.
people are used to listen to people selling things. Not how he is saying but what he says. People have to learn to listen.
His sentences show that his level of English is very good. I think he speaks slowly because he is very precise and careful when choosing the words.
So refreshing to see such a humble genius who is worthy of praise. You can see he dont feel he deserves all this attention he dont seem to want it. Which is so amazing bc so many who have no talent no brains recieve so much attention and they eat it to right up and are the opposite not humble.
What a gentle man. He is a great thinker and genius. Humble and kind.
Big pharma must hate this bloke...ain't no money in autophagy.
IT IS A FACT THAT EXAMPLES WORK MORE UPON THE MIND THAN PRECEPTS.I HAVE BEEN FASTING SINCE I WAS YOUNG (A MONTH EVERY YEAR) NOW THE THING IS I AM ALMOST 70 AT THE MOMENT AND STILL I FEEL (BOTH MENTALLY AND PHYSICALLY I AM STILL 25!!!)
Congrats!
I started 2 months ago and I want it to become my way of life
Great , I wish to know your practice of fasting in a bit detail.
Be kind enough to reply..
@@umeshmysoreshivaraju26 i think he means ramadan
but ramadhan fasting is less than 16 hours...not enough for autophagy infact muslim have the same health issues compared to people who doesnt take fasting in ramadhan.....people should fast not only on ramadhan but on daily basis every month...ramadhan fasting is not special in term of health compared to ketogenic fasting backed up by science
@@brainfulness2189 of course they have issues eating sugars in the 12 hours idk how but some people end up gaining alot of weight
What a lovely gentle man. Glad I started being involved in fasting and autophagy about 5 years ago as well as time restricted eating. Problem is the people who would benefit the most from improving autophagy consider the whole field esoteric and for the fanatical few
It was awesome to listen Autophagy from its discoverer. Good luck to him in his future work. I have so much respect for him 🙏
I don't know why but watching this interview makes me very emotional.
Dr. Ohsomi is such an intelligent and beautiful soul. Thank you Naomi for sharing this amazing interview with us 💗
You are DIVINELY guided and protected 🙏🌹😄
OH!! THANKS SO MUCH FOR THE INTERVIEW 👍
What a humble man!
Great post. Highly appreciated. Thanks
Thank you for this interview with this Giant, the shoulders on which all those in the “autophagy arena” stand. What an incredible human. Thank you, Sir. 🙏🏽
What a Noble Man..
Really Wonderful Thoughts of Dr. Oshumi..
Love you Sir 🙏🙏👍👍💕
Thank you Naomi for sharing this amazing interview with us. Very inspiring. ❤️
What a huge debt of gratitude we owe to this beautiful Japanese man. ❤️❤️❤️❤️ Valerie Farrington 🦋🦋
"We only understand about 30% of the science and working of autophagy", he says. !! That needs to be on a big banner flying across all the vids claiming ANYTHING about autophagy.
Enjoyed this video very much.
Agreed, Susan. It's just the tip of the iceberg. So glad you enjoyed it!
The rest of us can learn a LOT from that. Too many yahoos arond. Majority of them are young too, just because their parents told them they are better than anyone else. This man has devoted his career to his science and it took him decades to come to this point. Herein is the wisdom only the truly wise who are willing to listen can use.
Now you have your handy excuse to change nothing, live as you always have and learn absolutely nothing new. Congratulations on your mediocrity
@@stalstonestacy4316 No need to be a b*tch
Anyway that 30% is a lot. You are taking one point to deny the fasting and the people who are spreading the info about it. Idiot, pure BIAS
Thank you @Naomi for sharing this amazing interview. Thank you so much Dr. Yoshinori for your great job, saving our life by authophagy.
Fantastic interview. What a lovely man. 🙏
Jackie! A pure and brilliant individual. Naomi
Congratulations, this term autophagy was just very new to me and I try to share as much as I can. Thank you for bringing this to us.
Julietzki Zara This is no where a brilliant discovery, Indians defined and proved this millions of years ago and they are practicing this from then owards...
Two thousand five hundred years ago, the Buddha, experimented with different life styles. Born into royality, he led a luxurious life, but was disillusoned by the suffering of the poor as well as that of the wealthy who suffered because of over indulgence. He thus advcated the middle path, refraining fom starvation , as well as from gluttony, by eating once a day before noon. A pratice that is followed by countless buddhist monks , at the present.
So interesting! I am so fond of this gentle man:) I had no idea that most of the protein that our body uses every day is from autophagy, not from our ingested protein.
I think she was asking another question before he finished responding. He is capable of much more information than what we got.
Great interview. A lot of class on the part of both individuals.
Thank you very much :)
Please note:
Dr Ohsumi is a scientist. His work and that of his team that won a Nobel prize, was their identification of genes which made it easier to study autophagy.
As of this interview he stated they understood about 30% of autophagy IN YEAST (30 years of work). Mammalian cells (that’s us) are more complex.
In this video there was no mention of fasting or a specific diet. No mention was made of any specific way to enhance human autophagy or even if that was desirable.
There was mention that in future, it may be possible to develop medication that would control the autophagy processes.
Research continues….
He is a noble scientist ! My humble respects to you sir !
Hopefully in the future, my children (now less than 9yo) interested in learn and research about autophagy.
Great humble man. His face is so innocent like child. Naomi is also looking smart
The way you set the tone of the interview is amazing. I liked words such as "contrarian."
watched it in 2x speed with subtitles not gonna lie... despite that, great interview!
I am so grateful to you.. I am so thankful to you.. you are Awesome..
Thanks a Billion
I sense the spirit of humor and kindness in his voice.
This is how you realize how your BODY IS MORE POWERFUL than you can imagine (not only your Thoughts!)! There is an enzyme in our body that can minimize aging, and is harnessed through the correct meditation and energy exercise (yoga? qi gong?...who knows!). We will wait for the next nobel prize winner to discover this! ;)
Exactly! ;)
I got teary! Thank you so much for this!
This is an honor he's a genius I can listen to him for hours I'm so grateful to God for this humble genius man and for Finding this video thank you thank you
beautiful and informative talk , gracias Naomi
Mauricio
What s autophagy means? How can we do that.
In India, we have been following fasting methods for thousands of years... But because of religious reasons. In our ancient religious books/ literature/ Vedas, the long water fastings have been given lots of importance. Every where it is mentioned that in a healthy body lives a healthy mind. So when you sit for meditation ( which is way to feel/ meet/ sense the GOD), first you cure/ purifie your body with fasting, so that you could sit easily and concentrate / meditate. I think they entangled fasting with religion so that people would follow it for the sake of GOD if not otherwise.
Agree. Religion, when used wisely by very ethical, honorable, discerning leaders, is ultimately beneficial for its practitioners. Monks and nuns have also practiced fasting and meditation in the form of prayers & vigils. What Dr Osumi has learned and expounded on is the scientific basis for these practices. Oftentimes our "modern" minds scoff at something we don't understand and discard traditional knowledge as ancient balderdash until we see the validity of it with our own eyes.
Totally agree. The ancient epic Mahabharata say: it was by fasts the deities have succeeded in becoming
denizens of heaven. It is by fast that the Rish have attained high success. Chyavana,
Jamadagni, Vasishtha, Gautama and Brigu - all these great Rishis endued with the virtue of
forgiveness have attained to heaven through observance of fasts. In former days Angirasa
declared so unto the great Rishis. The man who teaches another the merit of fasts has never to
suffer any kind of misery. The one who daily reads this ordinances (about fast), or hears them becomes freed from sins of every kind
May I ask
In average, how old a healthy Indian live?
@@kmarquez6362 en.wikipedia.org/wiki/List_of_countries_by_life_expectancy
@@Wenchlock123 thank you!
I like the way u are talking. U are a great advisor and interviewer.
When I look closely at the radiance of this man, I almost forget that aging is something negative.
But my question is:
To what extent could autophagy support or eliminate one of the seven points that make up the Aubrey de Gray theory (intracellurar junk)?
Does autophagy also clean the collected garbage outside the cell?
This last question seems to me to be of central importance for the appearance of a human being (speaks beauty of the skin).
Senescent Cells in Skin Aging
www.karger.com/Article/FullText/444877
❤️ Thank You ❤️
Thank you so much
Naomi, Thank you for the fantastic video.
Thank you for watching!
Arriba Oaxaca prino
One of the best interview
Thank you Naomi 😍🌹for sharing this video with a humble but great person for his wonderful work on autophagy. 2 Questions: (1) How many hours before the process of autophagy takes place ? Would a 16/8 intermittent fasting protocol help or do we need a longer period (2) Dr Ohsumi’s comment about protein: does it mean that we should not consume too much protein as it might affect the autophagy process ?
21:12: Aww, I think he would have been quite excited to hear more about it, and would probably have some interesting comments on it, if you could have gone into it a bit more. But keeping it on a broad level was probably the best choice.
As it's an interview, and not a "reviewing science of autophagy with the initiator of the research on it" -- though that's something that'd be really exciting for me in any case! ^^
26:45: It's amazing and great that he's still excited to do more of the basic and very essential research of improving the methodology of studying autophagy!
Thank you Naomi for conducting this lovely interview! He's such a patient and humble man!
I read a lot of comments about how much of a genius he is, and while that may be true I’m more interested in what people are taking away from his work in practical day to day applications.
1. That protein synthesis comes from autophagy of our own protein cells. Therefore we must replace that protein through diet, not just for muscle growth but for all the bodies processes that require protein.
2. The way our body synthesizes protein is also the reason why we lose muscle mass if we don’t get enough protein in our diet, as well as poor health due to the organs cell requirements.
Dear ms whittel... You made me understand why a Belgian man got the title of viscount in 1989. It was Christian de Duve. Recipiant of the Nobel Price of physiology in the seventies for his work on the lysosome and coming up with the term autophagy. Thx for that.
amazing to see how a genius looks and sounds, thank you for sharing!!
Too difficult to understand. Would love to see a written copy of what he was saying. Thanks for this interview.
click on the CC button on the bottom bar of the video to get subtitles. it's not perfect but very helpful.
Listen carefully, you will understand.
I found speeding it up 1.5x made it easier for me to comprehend the doctor.
So fascinated I’d love to learn SO much more (reading your book Currently)
Thank you Sr for the effor,so we anderstand,,for both,🙏😚😙🙏💞❤💪
Brilliant person best part of human
Astonishing research by brilliant scientist
In India they have been practicing this for thousands of years!
Dear Naomi, I stumbled over this video one year too late but what a pleasure to see it. More than the content and the interviewee (who is very distinguished of course), the clip is enriched by your interviewing style, personal charm and demeanor. Saying, just in case you find this message in the bottle :-). I am reading your blog now.
For me it was a healing experience to watch this tender woman interviewing this humble genius, the synergy of the to of them heals me.
Thanks for this live interview! Please let me know how to find a version with subtitles to understand perfectly...Naomi.
This is just tip of the ice berg.This fasting was a weekly practice in siddha and ayurveda.There will be shockwaves in this world when modern science acknowledges and properly researches about life force energy and bramacharya( advanced version of no fap)
Intelligence + humility makes people great!
Important interview however needed a strong introduction and orientation to better grasp the topic.
Thank you for posting! It would be so awesome if you can summarize what he said. It was not easy to understand him. I am fascinated. 😊
Omg ❤ my favourite guest . Please pronunce it autophagy
Humble genius
Would it be possible to get a transcript of this interview as I had trouble understanding? Thank you Naomi for sharing this.
Gwen, absolutely. We are working on this now. Best, Naomi
Also in my opinion very desirable
@@naomiwhittel so, is he saying that we have a long way to know exactly the mechanism by which some or all cells behave or degrade. That is, will long term fasting necessarily protect all or some cells or does it really depend on which part of the body the cells are located.
Are you sure you don't understand or is the volume too low???
Dear Naomi, I would like to know more detail and sample of his recommendation, his diet. I'm in depression and need some way to survived.
What an impressing man.
Btw., I like his glasses, too. :-)
Genius _rare and so devoted
Mehtab Shams This is no where a brilliant discovery, Indians defined and proved this millions of years ago and they are practicing this from then owards...
Great interview! But I wish you had asked him if he himself practices Autophagy to stay younger and healthier.
Brilliant!! Since it is a rare interview, we really would have liked to understand his words. Good English, just not too understandable. Thank you for adding subtitles soon.
What a lovely interviewer!!
Could someone clarify what the doctor meant when he spoke about protein?
This brilliant pioneer exudes such self-evasive humility - so typical in Japanese culture - that he seems to be uncomfortably embarrassed by effusive comments from the interviewer - so typical in American culture.
30% understanding of autophagy can manage to get Nobel Prize. So the blue ocean is still great benefits to venture and explore.
Real genius. 🙏🙏🙏
It is a wonderful discovery, but why this discovery did not avoid the features of aging visible to him, or the real aging in the cells of the body ..
Turn on closed captions.
Your welcome.
Hatts up sir great scientist 🙏🙏🙏
🙏 I start already with 72 hours I feel super 🙏
Does he mention how long he recommends people fast to achieve autophagy?
How to start autophagi...and how much hours i have to live in fasting situation...what could be taken during autophagi......??? Thankyou.
Came here for the IF, stayed for the Naomi hotness factor
Too bad there wasn't subtitles. It would be easier to hear him.
Maria Butler on the youtube app there is a setting for subtitles
Maria, thank you. We will add the subtitles! Naomi
Oh good! I was having a difficult time. I'm listening to it again. Subtitles would be helpful.
Maria Butler use the close caption setting.
Maria Butler Yes, he’s very soft spoken and his English is slightly limited, but if you’re using a laptop or desktop, at the bottom right side there’s a CC button for subtitles, and if you’re on a mobile device tap on the 3 dots at the top right of the screen and select captions there.
Amazing! Can someone explain more in our everyday language
Regards to this interview?
Thank you!
Just Fast
Thank you for watching! Visit Glow15book.com to learn more. ~ Naomi's Care Team
@@naomiwhittel you mean buy the book
@paul doran toilets are not required for a human being ...as shit turns into soil.. u need to know that shit
very rare and good interview.