Granulation Defects | Tablet Manufacturing Problems | Reasons & Remedies Of Granulation Problems

[@Emrankasuriworld]

Informative

[@aabdeengaming1012]

Bahu sare student samjhenge sir

[@kothakapusreedevi4039]

super sir

[@kothakapusreedevi4039]

zsuper

[@Pharmainform]

Thanks

[@monsoonboy]

Sir why we check tablets in process parameters during time to time ?

[@Pharmainform]

to ensure that tablets are compressed according to specifications mentioned in BMR and there is no deviation from standard values.

[@monsoonboy]

@@Pharmainform sir how tablets excipients values are fixed please suggest best formulaes

[@Pharmainform]

Soon i will record a video for it

[@monsoonboy]

@@Pharmainform thankyou in adv sir

[@Pharmainform]

well come

[@ABHAY-bk5up]

Sir if the granules are over dried what is the solution for that?

[@ABHAY-bk5up]

@@Pharmainform Please sir can u explain me more?

[@Pharmainform]

if grains are over wet and over dried it results in very hard granules making drug release slow so we reduce the particle size to enhance drug release due to large surface area.Can use more disintegrant as well.
If granules are normally wet & are over dried it may result in capping, lamination so we apply moisture to the granules

[@ABHAY-bk5up]

Sir what happen when lubricant is over blended with the dried granule? And how?

[@Pharmainform]

it may result in capping or lamination

[@ABHAY-bk5up]

@@Pharmainform Does it effect DT?

[@sandipnayak4939]

please Hindi me