Therapeutics Initiative
Therapeutics Initiative
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วีดีโอ

Dr. Caspar J. Van Lissa: Text Mining Systematic Reviews: New Directions for Qualitative Research
มุมมอง 792 หลายเดือนก่อน
TI Methods Speaker Series: Text Mining Systematic Reviews: New Directions for Qualitative Research Synthesis. Presented by Dr. Caspar J. Van Lissa on 31 July 2024.
Dr. Jennifer Petkovic: Equity in Evidence Synthesis
มุมมอง 673 หลายเดือนก่อน
TI Methods Speaker Series: Equity in Evidence Synthesis. Presented by Dr. Jennifer Petkovic on 26 June 2024.
BC Provincial Deprescribing Series Webinar #7
มุมมอง 2123 หลายเดือนก่อน
BC Provincial Deprescribing Series Webinar #7. Presented by Dr. Shawn Gill, Dr. Marrison Marwood, and Dr. Shayna Henry on 12 June 2024
Dr. Larissa Shamseer: Preprints: Catalyzing Equity and Integrity in Scientific Discourse
มุมมอง 494 หลายเดือนก่อน
TI Methods Speaker Series: Pre-prints: Catalyzing Equity and Integrity in Scientific Discourse. Presented by Dr. Larissa Shamseer on 29 May 2024.
Dr. Mark Horowitz: Antidepressant withdrawal effects and how to safely stop them
มุมมอง 11K5 หลายเดือนก่อน
TI Best Evidence Webinar: Antidepressant withdrawal effects and how to safely stop them. Presented by Dr. Mark Horowitz on 8 May 2024.
Matthew B Jané: Artifact corrections for effect sizes
มุมมอง 905 หลายเดือนก่อน
TI Methods Speaker Series: Artifact corrections for effect sizes. Presented by Matthew B Jané on 24 April 2024.
Prof. Stephen Senn: Research synthesis is older than you think. Some early pioneers of meta-analysis
มุมมอง 2036 หลายเดือนก่อน
TI Methods Speaker Series: Research synthesis is older than you think. Some early pioneers of meta-analysis. Presented by Professor Stephen Senn on 27 March 2024.
BC Provincial Deprescribing Series Webinar #6
มุมมอง 1K7 หลายเดือนก่อน
BC Provincial Deprescribing Series Webinar #6. Presented by Dr. Juan Maria Rubio Lopez and Sadie Quintal on 13 March 2024
Dr Jessica Otte, Dr Aaron Tejani: Becoming an evidence detective - Critical appraisal for clinicians
มุมมอง 1137 หลายเดือนก่อน
TI 2023 Annual Conference: Becoming an evidence detective - Critical appraisal for clinicians. Presented by Dr. Jessica Otte and Dr. Aaron Tejani on October 14, 2023.
Dr. Javier Bracchiglione: Overlap of primary studies in overviews
มุมมอง 1337 หลายเดือนก่อน
TI Methods Speaker Series: Overlap of primary studies in overviews. Presented by Dr. Javier Bracchiglione on 28 February 2024.
Dr. Josh Levin: What is Portrait Online?
มุมมอง 307 หลายเดือนก่อน
What is Portrait Online? Presented by Dr. Josh Levin.
Dr. Tom Perry: Case-based polypharmacy
มุมมอง 2047 หลายเดือนก่อน
TI 2023 Annual Conference: ACase-based polypharmacy. Presented by Dr. Tom Perry on October 14, 2023.
Dr. Cait O'Sullivan and Dr. Vincent Wong: Bupropion - A discussion of its efficacy and safety.
มุมมอง 1588 หลายเดือนก่อน
TI 2023 Annual Conference: Bupropion - A discussion of its efficacy and safety. Presented by Dr. Cait O'Sullivan and Dr. Vincent Wong on October 14, 2023.
Dr. Tom Perry: Using simple pharmacokinetics to optimize prescribing
มุมมอง 1088 หลายเดือนก่อน
TI 2023 Annual Conference: Using simple pharmacokinetics to optimize prescribing. Presented by Dr. Tom Perry on October 14, 2023.
Dr. Wade Thompson: Statin deprescribing for older adults
มุมมอง 6818 หลายเดือนก่อน
Dr. Wade Thompson: Statin deprescribing for older adults
Dr. Anshula Ambasta: Approach to rational laboratory test utilization
มุมมอง 1349 หลายเดือนก่อน
Dr. Anshula Ambasta: Approach to rational laboratory test utilization
Dr. Rita McCracken and Dr. Wade Thompson: Is any sleep medication ever a good idea?
มุมมอง 2219 หลายเดือนก่อน
Dr. Rita McCracken and Dr. Wade Thompson: Is any sleep medication ever a good idea?
Dr. Colin Dortmuth: Likelihood ratio meta-analysis
มุมมอง 7110 หลายเดือนก่อน
Dr. Colin Dortmuth: Likelihood ratio meta-analysis
Dr. Guylène Thériault: Is screening misunderstood?
มุมมอง 70410 หลายเดือนก่อน
Dr. Guylène Thériault: Is screening misunderstood?
BC Provincial Deprescribing Series Webinar #5
มุมมอง 15410 หลายเดือนก่อน
BC Provincial Deprescribing Series Webinar #5
Eitan Agai: Addressing challenges for applying systematic review methods using AI
มุมมอง 9011 หลายเดือนก่อน
Eitan Agai: Addressing challenges for applying systematic review methods using AI
Krystle Amog: Right Review tool: development, evaluation and application
มุมมอง 8411 หลายเดือนก่อน
Krystle Amog: Right Review tool: development, evaluation and application
Dr. Tom Hardwicke: Improving science through meta-research
มุมมอง 111ปีที่แล้ว
Dr. Tom Hardwicke: Improving science through meta-research
A brief introduction to using Portrait Online. Presented by Alecz Reyes and Arrietty Song
มุมมอง 41ปีที่แล้ว
A brief introduction to using Portrait Online. Presented by Alecz Reyes and Arrietty Song
Dr. Carole Lunny: Introduction to a new risk of bias tool for network meta-analysis
มุมมอง 159ปีที่แล้ว
Dr. Carole Lunny: Introduction to a new risk of bias tool for network meta-analysis
BC Provincial Deprescribing Series Webinar #4
มุมมอง 296ปีที่แล้ว
BC Provincial Deprescribing Series Webinar #4
Dr. David Juurlink: Relieving pain in the era of fentanyl
มุมมอง 571ปีที่แล้ว
Dr. David Juurlink: Relieving pain in the era of fentanyl
Dr. Kim Encel: Social media is a goldmine for academics but why aren’t they using it?
มุมมอง 59ปีที่แล้ว
Dr. Kim Encel: Social media is a goldmine for academics but why aren’t they using it?
Dr. David Menkes: Antidepressants and substance misuse; what’s going on?
มุมมอง 253ปีที่แล้ว
Dr. David Menkes: Antidepressants and substance misuse; what’s going on?

ความคิดเห็น

  • @JamilaLoubrielModelActress
    @JamilaLoubrielModelActress 14 วันที่ผ่านมา

    That’s my old psych ! He knows his stuff !! Somebody def needs to call this OUT!! I’m here for it !!!

  • @DavidCurryFilms
    @DavidCurryFilms 14 วันที่ผ่านมา

    God only knows why the liquid form is the prescibed way to taper off. I had to beg my PCP to see a psychiatric pharmacist to get liquid... even then 1mg changes from 10-9-8 are drastic and painful. Those shit heads told me to keep going on just 5mg when alternating 10-5 put me in crisis 😭.

  • @arthurmurfitt7698
    @arthurmurfitt7698 20 วันที่ผ่านมา

    Dr. Mark Horowitz is a beacon of light in the darkness… 🙏🏻❤

  • @mudbutton2
    @mudbutton2 24 วันที่ผ่านมา

    I was put on 10mg of Lexapro by my GP as I was going through a stressful life event, some 12 years ago. I was never told about coming off, how long to stay on, or what it was like to stop. About three years later I tapered off and felt OK until a stressful event soon after stopping, whereupon I had worse anxiety and panic than I had before I went on the drug. So I went back on. I later had my dose increased to 20mg by a psychiatrist. I'm tired of the side effects (tinnitus, a bit of weight gain and I just hate taking drugs which I think I'm only on because I can't get off. ) I tapered off once again several months ago and was feeling ok but once again another life stressor soon after threw me into anxiety and panic. I think I just had not adapted and had maybe tapered too fast. I am tapering very slowly now, and hope to be free of this drug in maybe a year or so. I'm in no hurry because no way do I want to feel the terrible discontinuation effects, which are downright dangerous. Think very carefully and get proper advice before starting psych drugs.

  • @woodyshade
    @woodyshade 26 วันที่ผ่านมา

    Do side effects go away after few weeks or they are permanent?my doc says they won t subside.

  • @ashleynanos57
    @ashleynanos57 26 วันที่ผ่านมา

    Youre truly amazing. Thank you for this and for sticking up for all these people who are gas lit by their doctors. The world needs more of this.

  • @AngelWings-uu7rh
    @AngelWings-uu7rh หลายเดือนก่อน

    Dr are clueless. I was also told relapse. I was assaulted and hospital put me on AD

  • @janetmorrison2710
    @janetmorrison2710 หลายเดือนก่อน

    Why aren't the Dr's following what you are saying as I have mentioned this to my Dr's and they refuse to follow your suggestions on how to come off peroxitine also been told they don't prescribe lower doses like drops ect.Can you give me answers to this.

  • @mr.greengold8236
    @mr.greengold8236 หลายเดือนก่อน

    Please tell me what someone should do when they have gone cold turkey for a month and now experiencing withdrawal symptoms. Gone cold turkey on escitalopram (first 10 mg - for 3.5 years, then 5mg for 3 months till 1 Aug 2024), as of now its been 25 days, experiencing anxiety, irritability, sleep disturbance and low mood, burning sensation only first 1 to 2 hours after waking up, no brain zaps or balance issues. What should I do? Should I brave through with supplements or should I reintroduce and do slow taper, afraid of paradoxical reactions but withdrawal symptoms are horrible. If I reintroduce at what dose? If supplements, which supplements?

  • @vincemarshall8550
    @vincemarshall8550 หลายเดือนก่อน

    brilliant video that gives me some hope ,been on 20mg citalopram for 11 years thinking i was permanently screwed by anxiety ,looks like i have a fight on my hands but at least theres a strategy i can follow ,thank you Dr Mark

  • @claireh.7605
    @claireh.7605 หลายเดือนก่อน

    You have to schedule and wait for an appointment and then you have to have the skills to discuss things with a doctor: why wasn’t this info given when this med was prescribed? Had I known you need patience and diligence to quit, I would have been started it!!

  • @vincemarshall8550
    @vincemarshall8550 หลายเดือนก่อน

    thanks for this ,i finally found a word for the description of what im feeling when i try to withdraw from ssri,s .......akathisia ,its so insidious but at least i have a name for it

  • @dtseringdorje
    @dtseringdorje หลายเดือนก่อน

    After taking dopes called as antidepressant you are left fucked up even more than before treatement. Who profits on you...? Figure it out before professionals tell you do what you are told and take your pills for your own good.

  • @monamour3414
    @monamour3414 2 หลายเดือนก่อน

    I have been trying to taper again off of Cymbalta for 2 years. I am going through hell with severe anxiety and panic sensations. It's a nightmare! Been using a compounding pharmacy and they haven't been using a hyperbolic taper. I really need help!

    • @susanmorgan4151
      @susanmorgan4151 2 หลายเดือนก่อน

      You sound like me. I'm so sorry. I'm 14 months off at this point. Expect to experience "windows and waves" . Getting enough sleep is imperative. For me , SMALL doses of Marijuana helps. But each person responds differently. ....so be careful with any medication. I found my body/brain responds differently to most meds , then before withdrawing from SSRI's. So again , be careful . You can do this.❤

  • @nicolascamacho319
    @nicolascamacho319 2 หลายเดือนก่อน

    Damn psychiatrists.... they destroy lifes. I wish I have never met one of them

  • @nanadoodlez4209
    @nanadoodlez4209 2 หลายเดือนก่อน

    I'm so grateful to find your videos and learn about your studies. I believe this is vitally important. I've been following protocol from Facebook support group, Cymbalta hurts Worse. The moderators are so compassionate and very wise, especially Maria Pastoor. (who I saw you interviewed at beginning of July 2024). I began my taper from 60 mg capsule. After 20+ years of taking it I began my taper on 7/21/2020 (I find creating a spreadsheet to document my progress and symptoms has been very helpful). presently I am only taking 2mg/daily, although I take 1/2 dosage twice a day, because Cymbalta has an extremely short half-life of 12 hours & every 3 weeks I know I won't be able to sleep well for 3-5 days, experience hot flashes, anxiety, spiky headaches, pain & numbness down arms and legs. I started this withdrawal at age 69 and I'm now 73. Listening to this presentation has given me hope that I'm not beginning dementia, although it could be possible as both my mother and older sister had dementia. At my age it's hard to determine if the taper is to blame for my decline in my physcial and mental health. I fear hospitalization because in the US, they don't allow you to bring your own medications & they dispense it from their pharmacies. They don't recognize or understand the delicate balance with counting out tiny beads and that I must have Breckenridge as manufacturer. Back in 2020, no one understood the micro-dosing to taper. I've had a couple of weird episodes and would not go to the ER because of this fear. My pharmacist who fills my scripts laughed at me the first time I tried explaining what I intended to do, but in the past 4 years, she has become much more informed. My family Physician argued with me about the proper method but has agreed to continue prescribing it for me. I would probably be dead or institutionalized if it wasn't for this peer group, Cymbalta Hurts Worse. Keep up the research. There are at least 40,000 of us who are deeply grateful!!!

  • @Jazzy0316
    @Jazzy0316 2 หลายเดือนก่อน

    I’m on venlafaxine SSNRI for 2 months and I’m stopping. I don’t want to go any further and risk something like this happening. After stopping for a week I feel Nauseous, tired, dizzy, and headaches , I don’t think 2 months is considered longterm

    • @dianemorrell9638
      @dianemorrell9638 2 หลายเดือนก่อน

      @@Jazzy0316 you're right. 2 months is enough to change brain chemistry. I am finishing a 4 year taper from 30 years of effexor. It messes with serotonin doesn't fix anything. So happy you are trusting your gut.

  • @Jazzy0316
    @Jazzy0316 2 หลายเดือนก่อน

    I’m on venlafaxine SSNRI for 2 months and I’m stopping. I don’t want to go any further and risk something like this happening. After stopping for a week I feel Nauseous, tired, dizzy, and headaches

  • @jiririnagl302
    @jiririnagl302 2 หลายเดือนก่อน

    Nice i have only 75 and 50 mg tablets of Effexor in my country, thats it. :D gues im fucked.

  • @janiebobs
    @janiebobs 2 หลายเดือนก่อน

    I am off Citalopram after 16+ years. I am so short fused and swear readily. I have been off one month. Still have brain zaps, heightened emotions generally. I would say the anger/reactionary behaviours are tge worst symptoms. Worse than crying readily and zapping. From all I havecheard it could be a very long time before the withdrawal symptoms abate! There are not many success stories, if any, to help keep you going either which is almost ominous!.

    • @shellyschmidtRE
      @shellyschmidtRE 2 หลายเดือนก่อน

      I went off Citalopram 4 weeks ago, after 25 years. I'm still having withdrawals. My biggest physical distressing symptom is dizziness, and equilibrium issues....which cause nausea. Are you getting better? I am pretty much homebound.

    • @janiebobs
      @janiebobs 2 หลายเดือนก่อน

      I am determined to keep going. I still have somewhat 'immediate emotions ', but certainly more clarity of thought!

    • @tchillism
      @tchillism 2 หลายเดือนก่อน

      I was on Lexapro for 16 years as well. Tapered for six weeks. It’s been 2 1/2 months and I feel moderately depressed. I can still function fairly well, but I know the way I feel is not normal. Has anyone else thought about going back on their medication’s and then tapering according to his recommendations? Or having been off for 2 1/2 months maybe it’s better just to see the withdrawals through to the end..

    • @shellyschmidtRE
      @shellyschmidtRE 2 หลายเดือนก่อน

      @@tchillism You say you are functioning… Was there a time within those 2 1/2 months that you were not functioning? Did you steadily feel better during those 2 1/2 months? I tapered really quick at the direction of my doctor, about 3 1/2 weeks, I was on citalopram for many years. Equilibrium is the hardest part for me as it keeps me pretty much homebound. I am at four weeks since my last dose. I can feel my anxiety creeping in, especially in the mornings. I have generalized anxiety disorder, no depression. However, all of this has caused me to feel a bit depressed. I'm just wondering if you can tell me how you felt through the 2 1/2 months. As far as going back on your medication, I wonder about that each day as well, however, at this point I just feel like maybe pushing through to see where my baseline is Would be the better choice. Since I don't have depression, my doctor would like to see me go on Buspar for my anxiety, however, I'm pretty gun shy now about taking anything. If I did decide to try that, I think I would still want to see where my baseline is. I just need to be able to get out of my house and function.

    • @janeekitchen7727
      @janeekitchen7727 2 หลายเดือนก่อน

      @@tchillism Only you know you...but for me at 67 i want to try and see it through. I actually am thinking for clearly. x

  • @artealain
    @artealain 2 หลายเดือนก่อน

    Is this talk available to download and print out. I would really like to give it to my new doctor.

    • @drug_evidence
      @drug_evidence 2 หลายเดือนก่อน

      Thank you for your interest in Dr. Horowitz's presentation. The transcript is viewable by clicking on the description of the presentation (just below the video recording on TH-cam). Dr. Horowitz may also be contacted through his website for more information: markhorowitz.org/contact/

  • @joeallan3706
    @joeallan3706 2 หลายเดือนก่อน

    im lucky, i quit paxil 30mg after being on it over 20 years cold turkey about 2 months ago and had no withdrawal. whenever i attempted to before it was awful. after 7 days without it i was like "oh crap i didnt take my paxil for week! and i feel fine, im just going to quit" i feel so much better off that stuff. i have emotion now! and not just flat affect, its like i was living in black and white and the color is back now

  • @juliesaadwellness
    @juliesaadwellness 3 หลายเดือนก่อน

    Wow - the second case study! It’s shocking. I’m so angry on behalf of that young woman. No one listened to her at all.

  • @SEOExpertSojib
    @SEOExpertSojib 3 หลายเดือนก่อน

    You are uploading videos constantly but your contact not getting views or subscribers. Because there is some SEO problem. You should fix your content title, description, and tags. Make all things SEO friendly then your video will gain more views & your channel will grow. Let's discuss how we can enhance your channel's performance! I'm waiting for your response.

  • @vicklassen7227
    @vicklassen7227 3 หลายเดือนก่อน

    Dr could you please help. My husband tried to go off Effexor and then went back on, but for a week took double his dose. He ended up in er because of suicidal ideation. They said to go back down to his regular dose and he would be fine. He’s not fine. Inthe hospital again and now they put him on remron? Spelling wrong. Now it’s been 3 weeks and he is still unable to work, he can barely eat, can’t do anything. What do i do? The dr wants to put him on more drugs. I’m so afraid, please please help.

    • @vicklassen7227
      @vicklassen7227 3 หลายเดือนก่อน

      ​@@TheresaR.Amen Jesus is King. What dose of mitazapine are you on if you don't mind me asking

  • @icydev
    @icydev 3 หลายเดือนก่อน

    Very well said Dr Mark You, Dr Josef hottering. Bob whittaker, have all been life saving to me. I have been taking this drugs all the anti psychotics, benzos, mood stabilizers , SNRi etc from last 20 years and was still not improving and had cold turkeyed several times only to suffer the withdrawals with vengeance . But after going through your seminars , from the last 9 months have started the taper of 10% of the last dose and the wds are hell but manageable bcoz i am simultaneously reducing 3 drugs i.e Lamtrrgiene (mood stabilizers), Prozac (SSRI) and Duloxietene (snris). Have decided to go slow now as i have reached the 25% of my original dose on all 3 tabs. also taking omega 3 and vi- d and vit B12 supplements

  • @Snowflake1374
    @Snowflake1374 3 หลายเดือนก่อน

    I’m 9 months off zoloft 15 years use. Too fast taper by Dr. Severe WD. Feels like injury in my brain. Is there any hope? Will I be disabled for years. Cant work. Pain in my body. Feels like I lost myself and my life.

    • @icydev
      @icydev 3 หลายเดือนก่อน

      Hi @Snowflake1374 Sorry to hear that u are going through the worst of wirhdrawals, it has happened to me too several times as doctors used to rapidly taper me of Ads very quickly in a month and after 2-3 months used to suffer from sever withdrawals that i coludnt even get up from my bed and then again after 4 months of sufferings used to start on new drugs and the cycle repeated. In your case i wld recoomed that as u are already of the drug for 9 months, have seen in a video by Dr josef (he also makes very informative videos on withdrawals) that to reinstate the drug at 50%, so in your case restart at 25mg )hopefully ur symptons will decerse quicly and from there on start reuding the dosage by 10% of previous dose evey 1 month, so for 1st month it wld be 22.5mg, then 2nd month 20.5mg and so on , so it wld take around 30 months to get off the drug but it will surely take u out of the unimagianbele hell of withdrawal. hope it helps.

    • @susanmorgan4151
      @susanmorgan4151 2 หลายเดือนก่อน

      It's horrible. Yes , there IS hope. For me , having people in my life who "get it" is helpful. Talking about what you are going through helps. I would say be prepared mentally for a long withdrawal, but know it DOES get better. It does. A diet high in fat , low to no carbs or sugar seems to help me. Eat clean. Lots of water. Your brain is healing. ❤❤❤

    • @Snowflake1374
      @Snowflake1374 2 หลายเดือนก่อน

      @@susanmorgan4151 ❤️Thanks. Unfortunately, I don't have anyone who "gets it". Did you take them long term?

  • @whatevs1700
    @whatevs1700 4 หลายเดือนก่อน

    Please come back to Australia and set up a clinic here… Melbourne specifically… please 🙏

    • @nikeetamchutchison1547
      @nikeetamchutchison1547 3 หลายเดือนก่อน

      I would definitely see him if he was back here and would even travel from Sydney to Melbourne 100%

  • @mazymonroe8749
    @mazymonroe8749 4 หลายเดือนก่อน

    What length of time after your last dose is considered a protracted withdrawal? I'm 19 months off and still experiencing acute withdrawal symptoms 😢

    • @icydev
      @icydev 3 หลายเดือนก่อน

      Hi If u have tapered quicly, u will surely have nasty withdrawals and if u have tapered at 10% of last dose , the wds are quiet manageable and tapeeing shld continue to the ;ast of 0.01mg. if u are still having acute symptons means u havent withdrawaled prodperly. so my advice wild be start form the 25% of the dose from when u started tapering and start tapeing at the recommedned speed. hopefully u will have manageable wds. hope this helps

    • @dianemorrell9638
      @dianemorrell9638 3 หลายเดือนก่อน

      So terrible isn't it? Thing is time heals. Biochemistry is different for everyone and changes can happen quickly too.

    • @mazymonroe8749
      @mazymonroe8749 3 หลายเดือนก่อน

      2 years to withdraw! That is not too fast!​@@icydev

    • @mazymonroe8749
      @mazymonroe8749 2 หลายเดือนก่อน

      @@icydev I did a harm reduction taper over a long period of time so it has nothing to do with that. It has occurred because of long term use. It can take the brain a long time to heal and function without the meds!

  • @cheryl8956
    @cheryl8956 4 หลายเดือนก่อน

    I commend you for sticking your neck out challenging these drug companies. Your videos are inspiring, thank you.

  • @cheryllryan8440
    @cheryllryan8440 4 หลายเดือนก่อน

    38 years paxil and xanax and one week hospital to get off. Swear truth. Last October. Now what ??.

  • @susanmorgan4151
    @susanmorgan4151 4 หลายเดือนก่อน

    THANK YOU!❤

  • @karenpeart5997
    @karenpeart5997 4 หลายเดือนก่อน

    I have only been taking mirtazapine for 2 months , and i want to stop ( as i can not tolerate the side effects anymore ) I tried to stop but i got to day 3 and the withdrawal was horrific , feel terrible taking them a d terrible trying to get off tgem ( was put on them becauses of anxiety ( they do not really help , not very good with medication)

  • @arquipaje8441
    @arquipaje8441 4 หลายเดือนก่อน

    I´ve been tapering down from 5mg Lexapro, 10% reductions every two months, and now currently on 2.95mg. This is not medical advice to anyone, but taking the following supplements daily has helped quite substantially in tackling withdrawal symptoms: Vitamin D with K2: 4000units (morning) Vitamin C: 1gram (liposomal) (morning) Omega 3: 800mg EPA + 400mg DHA (at night) Magnesium Glycinate: 120mg (at night) Magnesium Threonate: 122mg (morning) Chaga Powder: 2g serving (served with tea, afternoon) Symptoms are mild the first three weeks after each reduction, then relatively normal functioning the following five weeks (with 1 or 2 miserable days)

    • @snowps1
      @snowps1 4 หลายเดือนก่อน

      How are you reducing the dosage? I have 5 mg pills. Are you just shaving them down? I went cold turkey and it's been 3 months and I'm starting to feel really miserable. I think I need to start it over and wean down but I don't know the best way to do it when I have pills.

    • @Liz-hc4um
      @Liz-hc4um 4 หลายเดือนก่อน

      Thank you for sharing this. I am back up to 5 in readiness to reduce. I went too fast and although no ‘neuro’ symptoms I was impatient, irritable, with bursts of anger and easily startled. I’m thinking of trying 4.5 mg next ( I have the liquid formulation). I am also going to stop trying to do this in secret because it’s been just awful for my relationship. I am also interested to hear that you’re doing this every too months…

    • @snowps1
      @snowps1 4 หลายเดือนก่อน

      @@Liz-hc4um oh my, I've also been doing it in secret and should just fess up to my husband. I'm so grouchy and moody now.

    • @arquipaje8441
      @arquipaje8441 4 หลายเดือนก่อน

      @@snowps1 I live in Chile, and we don´t have either liquid formulations available in the market, or compounding pharmacies that can prepare very small, specific doses of escitalopram. The only alternative I had was to buy the available 10mg Lexapro, which can be easily cut in half because of the notch on the reverse, and then shave each 5mg piece down with an always sharp scalpel to the desired doses. For this, I had to buy a 0.001mg precision scale. It is tedious as hell, and requires time and dedication to make sure you get constant doses. It´s the only way. I went cold turkey from 5mg to 0mg back in January 2011, and I was miserable for about a year and a half before going back to 10mg. I definitely would not recommend that!

    • @snowps1
      @snowps1 4 หลายเดือนก่อน

      @@arquipaje8441 thanks for the tips! I did pretty much stop cold turkey off 5mg and it's been a very rough couple of months, especially the wild mood swings!

  • @CarmenOrtiz440
    @CarmenOrtiz440 4 หลายเดือนก่อน

    Psychedelics definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it's just so hard to source out here

    • @JamesFJohnson
      @JamesFJohnson 4 หลายเดือนก่อน

      I’ve been researching on psychedelics and it’s benefits to individuals dealing with Anxiety, Depression, ADHD and from my findings, they really work and I’ve been eager to get some for a while but its been difficult to get my hands on them.

    • @AlbertoTorres894
      @AlbertoTorres894 4 หลายเดือนก่อน

      The Trips I've been having really helped me a lot. I’m now able to meditate and I finally feel in control of my emotions and my future and things that used to be mundane to me now seem incredible and full of nuance on top of that I'm way less driven by my ego and I have alot more empathy as well

    • @LucyFernandez628
      @LucyFernandez628 4 หลายเดือนก่อน

      I was having this constant, unbearable anxiety due to work stress. Not until I came across a very intelligent mycologist. He saved my life honestly

    • @Rogerseegren271
      @Rogerseegren271 4 หลายเดือนก่อน

      ​@@AlbertoTorres894I feel the same way too. I put too much on my plate and it definitely affects my stress and anxiety levels. I am also glad to be a part of this community.

    • @AnaSolano190
      @AnaSolano190 4 หลายเดือนก่อน

      ​@@LucyFernandez628Does he deliver to various locations?

  • @Me-fs5mi
    @Me-fs5mi 4 หลายเดือนก่อน

    Execelent presentation Mark. Especially the graphs ( VISUALS)......they are true for most taperings I imagine. How would a graph look for those who have successfully stopped the drugs? For younger people who have a fighting chance? What might success look like?

  • @JasonBrown-dd7dj
    @JasonBrown-dd7dj 4 หลายเดือนก่อน

    Thanks Mark, doctors need to recognise this if they knew the damage they can and have done to patients they wouldnt be quick to prescribe.Opiates,benzos ,gabapentinoids and antidepressants can be really damaging.Informed consent thats all patients advocate for.Your a genius in your field of work.Theres people in psych wards that are ill cos these meds victims.

  • @nicolasmezaconcha7686
    @nicolasmezaconcha7686 4 หลายเดือนก่อน

    Thank you for your excellent presentation, Javier

  • @shahnazali4000
    @shahnazali4000 4 หลายเดือนก่อน

    Please can you guide me how to taper successfully Closopine. The doctor initially put my nephew at 450 mg. He withdrew by himself reducing it by 100mg. i.e 350 mg. Thereafter 25mg every 8 weeks or more. He wants to completely ween off this medication. The psychologist is refusing to his tapering. Where can he get help, to overcome withdrawal symptoms ...esp. suicidal symptoms, as this has happened when earlier he was put on Risperidon , which actually causes suicides...PLEASE HELP !

    • @kalaiselviramaiah3854
      @kalaiselviramaiah3854 2 หลายเดือนก่อน

      How you are doing now pls go to website for help

  • @janebond8342
    @janebond8342 4 หลายเดือนก่อน

    This is why I NEVER take pharmaceuticals

  • @pradeepdatta2168
    @pradeepdatta2168 4 หลายเดือนก่อน

    Excellent presentation.Dr Horowitz may kindly also do presentations on tapering by elderly patients as their cases are different from other adults ie < 65 years.

  • @sapiensfuturus
    @sapiensfuturus 4 หลายเดือนก่อน

    Do Vyvanse!

  • @kevk741
    @kevk741 4 หลายเดือนก่อน

    Antidepressant injury and antidepressant tapering injuries are real. Mark knows exactly what he’s talking about so listen up! Find Nicole Lamberson PA and hear about her benzodiazepine injury and listen to her discussions for the award winning documentary “Medicating Normal”. Learn about injuries like chronic and tardive akathisia. Find Dr. Shipko in Mad in America and hear about his work with tardive akathisia from antidepressants. I want to see all 1:6 adults on antidepressants get tapered off and see how many people actually get hurt.

  • @halk3
    @halk3 4 หลายเดือนก่อน

    My doctor makes a distinction between physical and psychological dependence. The concept of psychological dependence seems invalid to me. The way it is described, it sounds like a reverse placebo effect, in which you experience adverse effects because you expect them. If so, then saying that withdrawal symptoms result from psychological dependence amounts to saying that it is all in your head. It is frustrating that my doctor does not take my symptoms seriously, but he is really just there to write the prescriptions, so I don't dwell on it.

    • @Mike_Iz_
      @Mike_Iz_ 4 หลายเดือนก่อน

      Your doctor sounds very uninformed like countless prescribers. Please convince them to watch this webinar or read over the Maudsley Deprescribing Guidelines which Dr. Horowitz recently published. It could save many patients lives from being ruined by their ignorance. 🙏

  • @Suzanneoakly
    @Suzanneoakly 4 หลายเดือนก่อน

    how do you access liquid forms of ssri so you can slowly come off

    • @Jbinkstar
      @Jbinkstar 4 หลายเดือนก่อน

      I would also like to know this too, my GP has recently told me they are not licensed in the UK but they are, so an outright lie. They told me to go on Amazon but a pill cutter and cut my tablets in half, then half again and then stop them 😮 So Very Dangerous what they tell us to do, it's so wrong.

    • @Mike_Iz_
      @Mike_Iz_ 4 หลายเดือนก่อน

      I want to know this too. Is it possible to get it from the UK if I live in Canada? A liquid formulation of venlafaxine is not available here. ??? I have very little trust in dose accuracy when counting or weighing beads/microspheres from the capsules of Effexor XR.

  • @susanmorgan4151
    @susanmorgan4151 4 หลายเดือนก่อน

    Dr. HOROWITZ , Thank you. I have experienced exactly what you are saying after titrating off Paxil per my subscriber instructions. I seriously thought I was losing my mind. I found myself in the fetal position sobbing - eventually blacked out. My gp said it was an anxiety attack , and prescribed anti-anxiety meds. That was a train wreck! I decided to stay off all psych meds....am still withdrawing after 11 months. It IS getting better though. A very SLOW process.

    • @icydev
      @icydev 3 หลายเดือนก่อน

      Hi @susanmorgan4151 good to hear that u have stopped theADs for 11 months but still facing withdrawlas. The thing is if u withdraw ADs cold turkey or too quicly it damage sthe brain and the brain goes in some kind of kindiling mode and the symptons dont go for years. As u have cold tukerred ur meds and if still facing delibelating wds, then my advice wld be to go back to 25% from which u have cold turkeyed and start reducing the dose by 10% of last dose there on every month. This way the damge caused to the brain will be reduced and will have bearable withdrawals/ hope this helps

    • @susanmorgan4151
      @susanmorgan4151 2 หลายเดือนก่อน

      ​@icydev , thank you. I did titrate as per my (then) doctors directives. Actually I went slower than he prescribed... it is now 14 months out for me. It's still very hard , but getting microscopically better. Yes , I believe my brain IS altered or wounded. I am now in a "windows and waves" cycle. Some days feel unbearable. Marijuana in very SMALL doses breaks the "wave " days up in manageable pieces. I don't recommend Marijuana, because we are all wired differently. For me , it helps.❤

    • @carolstaszak4339
      @carolstaszak4339 หลายเดือนก่อน

      Same thing happened to me. My doc took me off of Paxil after 24 years in 5 weeks while adding benzodiazepines and c/t’d after two weeks. Then started Prozac at its highest dose. My brain was shot. I’m still on benzodiazepine and Effexor.

  • @rhianonallen2947
    @rhianonallen2947 4 หลายเดือนก่อน

    Any chance that the original webinar participants can be emailed some of the data slides from the last half of the presentation?

    • @icydev
      @icydev 3 หลายเดือนก่อน

      Hi @rhianonallen2947 my advicew wld be go throgh the seminar again and the slides which u want u can take a sceenshot of it and use it for future refrence. hope this helps

  • @makingmentalhealthpositiveUK
    @makingmentalhealthpositiveUK 5 หลายเดือนก่อน

  • @claireh.7605
    @claireh.7605 5 หลายเดือนก่อน

    I DIDN’T start the antidepressants because of anger and irritability! But this is what I have when I stopped Lexapro.

    • @susanmorgan4151
      @susanmorgan4151 4 หลายเดือนก่อน

      Me too.❤

    • @Liz-hc4um
      @Liz-hc4um 4 หลายเดือนก่อน

      I experience it whilst reducing 😬

    • @snowps1
      @snowps1 4 หลายเดือนก่อน

      Me too! And depressive moods. I started it for panic attacks.

    • @claireh.7605
      @claireh.7605 4 หลายเดือนก่อน

      @@snowps1 my issue is that I now think that anger and irritability are good because somehow they are justified

    • @Yorkiepud1973
      @Yorkiepud1973 3 หลายเดือนก่อน

      I experienced anxiety and anger on it (escitalopram / lexapro) for 10 years, and over the 12 months of slow taper and during the last 6 months completely clean from these hard narcotics. I feel like i have been abused by the medical fraternity

  • @Dggttaj
    @Dggttaj 5 หลายเดือนก่อน

    This is very informative Thank you