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ECETOC
เข้าร่วมเมื่อ 5 ม.ค. 2012
ECETOC is the centre for chemical risk assessment. We are a platform for scientists from industry, academia and regulatory bodies who collaborate towards safer chemicals policies with science at their core.
Demystifying AI - A brief introduction
Hua Qian, PhD, gives an introduction to ECETOC's workshop "Integrating AI in chemical safety assessment - Opportunities, challenges and the path forward", starting form "what is AI?" and "why is everyone talking about it?".
📍 This presentation was recorded live during ECETOC's workshop "Integrating AI in Chemical Safety Assessment - Opportunities, Challenges, and the Path Forward," held in October 2024.
➡️ Watch more presentations from this workshop on ECETOC's TH-cam channel or visit www.ecetoc.org/event/ai-workshop/ for more information.
📍 This presentation was recorded live during ECETOC's workshop "Integrating AI in Chemical Safety Assessment - Opportunities, Challenges, and the Path Forward," held in October 2024.
➡️ Watch more presentations from this workshop on ECETOC's TH-cam channel or visit www.ecetoc.org/event/ai-workshop/ for more information.
มุมมอง: 16
วีดีโอ
A possible application of AI in toxicology - The Axiom Tool
มุมมอง 2114 วันที่ผ่านมา
Axiom's machine learning (ML) platform delivers high-quality safety data at a fraction of the cost of traditional experiments, aiming to replace physical lab and animal testing for molecular safety assessments. Initially focused on liver toxicity, the platform will expand to additional organs next year. Trained on a dataset of 50,000 molecules, including drugs, agrochemicals, and cosmetics, Axi...
Applications of Machine Learning and AI to Develop PBPK and QSAR Models for ADMET Prediction
มุมมอง 714 วันที่ผ่านมา
Machine learning (ML) and artificial intelligence (AI) are driving significant advancements in toxicology, particularly in predicting ADME (absorption, distribution, metabolism, and excretion) properties, developing physiologically based pharmacokinetic (PBPK) models, and building QSAR (quantitative structure-activity relationship) models for toxicity prediction. Dr. Zhoumeng Lin highlights rec...
Leveraging AI in the Virtual Human Platform for Safety Assessment (VHP4Safety)
มุมมอง 2014 วันที่ผ่านมา
The VHP4Safety project aims to revolutionize chemical and pharmaceutical safety assessments by building a Virtual Human Platform (VHP) that replaces animal testing with human-relevant approaches. Focusing on case studies related to kidney function, neurodegeneration, and thyroid-mediated brain development, VHP4Safety integrates pharmacokinetic models, human physiology data, and new methodologie...
Leveraging AI for Toxicity Prediction and De Novo Compound Design Using Cell Painting Data
มุมมอง 1314 วันที่ผ่านมา
The integration of artificial intelligence (AI) with cell painting-a high-content morphological profiling method-offers new possibilities for toxicity prediction and de novo compound design. David Rouquié explores how machine learning algorithms extract complex patterns from high-dimensional cell painting images to accurately identify toxicity profiles and underlying biological mechanisms trigg...
Generative AI for Toxicology and Drug Safety
มุมมอง 1514 วันที่ผ่านมา
🎙 Presented by Weida Tong, US FDA Generative AI technologies, such as Generative Adversarial Networks (GANs), are opening new frontiers in predictive toxicology and drug safety. Weida Tong discusses how the US FDA is leveraging GANs to: 1️⃣ Generate synthetic animal study data without conducting experiments. 2️⃣ Produce toxicogenomics data from experimental designs alone. 3️⃣ Translate toxicolo...
AI in toxicology - The now, the new and the next
มุมมอง 4714 วันที่ผ่านมา
Thomas Hartung, MD, PhD, John Hopkins University talks about what AI is doing - and can potentially do - to advance and innovate chemical safety assessment. 📍 This presentation was recorded live during ECETOC's workshop "Integrating AI in Chemical Safety Assessment - Opportunities, Challenges, and the Path Forward," held in October 2024. ➡️ Watch more presentations from this workshop on ECETOC'...
AI-assisted Next Gen Risk Assessment and SSbD Workflows enabled by FAIR Data and Knowledge
มุมมอง 2314 วันที่ผ่านมา
Barry Hardy discusses how FAIR (Findable, Accessible, Interoperable, Reusable) data principles are being used to support Next Generation Risk Assessment (NGRA) and Safe and Sustainable by Design (SSbD) workflows. By creating comprehensive datasets and knowledge graphs that connect compound information, biological responses, and pathways, Hardy outlines how these resources aid in AI-enabled risk...
FAIR data and data that is Fully AI Ready
มุมมอง 914 วันที่ผ่านมา
Erik Schultes (GO FAIR Foundation, NL) speaking at ECETOC's workshop "Integrating AI in Chemical Safety Assessment - Opportunities, Challenges, and the Path Forward," held in October 2024. ➡️ Watch more presentations from this workshop on ECETOC's TH-cam channel or visit www.ecetoc.org/event/ai-workshop/ for more information.
Introducing AI in EFSA Systematic Reviews
มุมมอง 2014 วันที่ผ่านมา
Watch Dr Fulvio Barizzone presents EFSA's strategic approach to integrating Artificial Intelligence (AI) into its Systematic Review (SR) processes, which are crucial for scientific assessments on food and feed safety in the European Union. EFSA’s vision for AI implementation in evidence management, as outlined in its 2020 theme paper and 2022 Roadmap, is a key focus of the presentation. The tal...
From Data to Decisions: AI's Role in Modern Toxicology
มุมมอง 6314 วันที่ผ่านมา
Artificial intelligence (AI) and machine learning (ML) are transforming toxicology by predicting chemical hazards, reducing animal testing, and accelerating regulatory decisions. Nicole Kleinstreuer highlights how AI-driven models turn large toxicological datasets into actionable insights, automate data curation, and support evidence-based regulatory frameworks. 🎙 Presented by Nicole Kleinstreu...
Exploring best practices in building qAOPs
มุมมอง 22010 หลายเดือนก่อน
AOPs are scientific ‘roadmaps’ that connect the dots between an initial molecular exposure to a substance or a stressor and any eventual harm that may occur to living organisms or ecosystems. Quantitative AOPs (qAOPs) allow scientists to use numbers and models to make predictions about how a living system will respond to different amounts of a chemical - and so predict how likely, or how severe...
Maternal thyroid hormone (T4) imbalance and neurodevelopmental effects in the progeny
มุมมอง 309ปีที่แล้ว
An ECETOC Task Force has studied potential links between endocrine disrupting effects chemicals of chemicals on the thyroid during pregnancy and breastfeeding - and what consequences these could have on the neurodevelopment of the baby. The work resulted in peer-reviewed manuscripts, published in Critical Reviews in Toxicology between 2020 and 2023, and in a tiered testing and assessment scheme...
Three-tiered approach for standard information requirements for polymers requiring registration
มุมมอง 377ปีที่แล้ว
An ECETOC Task Force has proposed a three-tier approach to information requirements for risk assessment of polymers. The proposal ensures that animal testing is only used as ‘a last resort’, while still ensuring the quality of data for the risk assessment. Polymers cover a broad spectrum of generally very large molecules, including e.g. cellulose, waxes, and resins. They are also constituents o...
TRA Worker Tool v3.2
มุมมอง 378ปีที่แล้ว
The latest version of the TRA Worker Tool is available now! Click on www.ecetoc.org/tools/tra-main/tra-download/ to download it - both in the updated Integrated Module or in a new standalone version. Users Guides for the TRA tools, as well as a revised FAQ, are also available for download at at www.ecetoc.org/tools/tra-main/tra-faq/. As mentioned in the video, updates concern the following PROC...
Health concerns for low tonnage chemicals and opportunities for NAMs
มุมมอง 55ปีที่แล้ว
Health concerns for low tonnage chemicals and opportunities for NAMs
Including georeferenced data to improve ecological relevance of chemical risk assessment
มุมมอง 160ปีที่แล้ว
Including georeferenced data to improve ecological relevance of chemical risk assessment
Putting the CF4Polymers into practice: Cationic polymers
มุมมอง 702 ปีที่แล้ว
Putting the CF4Polymers into practice: Cationic polymers
Considerations & Examples for Grouping of Polymers
มุมมอง 842 ปีที่แล้ว
Considerations & Examples for Grouping of Polymers
Assessing the safety of polymers: Examples of grouping approach
มุมมอง 7303 ปีที่แล้ว
Assessing the safety of polymers: Examples of grouping approach
Developing a new paradigm to assess degradation potential of chemicals
มุมมอง 663 ปีที่แล้ว
Developing a new paradigm to assess degradation potential of chemicals
Increasing ecological relevance of chemical risk assessment using geospatial approaches
มุมมอง 773 ปีที่แล้ว
Increasing ecological relevance of chemical risk assessment using geospatial approaches
What does it mean for you to be a woman in science?
มุมมอง 1014 ปีที่แล้ว
What does it mean for you to be a woman in science?
What is your advice to aspiring young scientists ?
มุมมอง 994 ปีที่แล้ว
What is your advice to aspiring young scientists ?
How can we communicate about science today?
มุมมอง 1075 ปีที่แล้ว
How can we communicate about science today?
What role does chemistry have to play in building a better future?
มุมมอง 1515 ปีที่แล้ว
What role does chemistry have to play in building a better future?
What is the value in looking to nature when seeking to solve human problems?
มุมมอง 585 ปีที่แล้ว
What is the value in looking to nature when seeking to solve human problems?
Mark Pemberton and Jim Bridges on Quantitative Weight of Evidence at ECETOC 'Omics Workshop
มุมมอง 1878 ปีที่แล้ว
Mark Pemberton and Jim Bridges on Quantitative Weight of Evidence at ECETOC 'Omics Workshop