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Why doesn’t rabies affect birds, and why is the vaccine only temporarily affective

15:15 so basically after fixing millons, cell realizes there is now billons and says "f it everyone dies now"(they infact did not all die)

Its so interesting as much as they are scary like, technically this is THE ultimate evolution, it can creat more of itself while being hard to kill Yet its deadly to everything that isnt itself

Rabies definitely isn’t worse than Alzheimer’s disease but nothing else gets even remotely close by comparison.

But if we can isolate and multiply archea and their viruses, we could introduce virulence factors to the archea phages/viruses and disprove (or prove) the hypothesis. Right? Is it actually that hard to do?

This video has made me realize there’s a whole area of science I know nothing about!

Maybe they are just very vulnerable to our complimentary system?

The "Rabies had 5 genes" chart fact didnt hit as hard as E-coli has 22% of the amount of genes as a human being TBH.

Sbeve

This is great. Thanks!

Yoooo shout out to the stock footage that showed the insane pink colour of the vaccine!

Would evolution be able to select against prions, even if they were only negative? If prion diseases are quite rare and progress quite slowly, presumably most instances would kill the organism after they had already reproduced?

You touched on it briefly when you mentioned that Archaea have different nutritional requirements. One thing to remember is that the way a lot of bacterial and fungal infections are identified is through culturing patient samples and identifying the predominant growth, mainly through the use of agar plates. These plates tend to be specialized towards a small subsection of the human microbiome and even some known pathogens won't grow without additional nutritional supplementation. It's possible that Archaean infections do occur, but may fail to appear by conventional identification methods. Coupled with the lack of research makes even identifying an Archaean infection significantly more difficult. Another factor could even involve masking by bacterial growth which could be attributed as the cause of infection instead of Archaea. For obvious ethical reasons, it's not like research teams can purposely attempt to infect people with Archaea to see if they cause infection. In the end the reason we're not finding Archaean pathogens is possibly because we're not looking for them.

I though showing 💀 was a gen Z joke. Maybe i have brainrot. What if brainrot is an symptom of a prion infection!?

Pleasee play Dota with me phy!

Damn, now I want a pet tartigrade...

Unlike for the newspeak 👍😛

Can someone summarize the vid to me? I am too lazy to watch it

In French Prions can also mean "We pray/We should pray". Its kinda fitting for this disease

so basically the researchers who made the Nagasaki Mice accidentally used the Heartbleed software bug but in DNA

archaea kisses 💕💕💕💕💕

Hasn't Eukarya included inside the domain Archaea?

wait Why would yeast want to have a prion disease? It suicides them. What's the point?

TIL Fatal Familial Insomnia is a prion disease. Jack Townsend from Tales From The Gas Station has Fatal Familial Insomnia.

Wouldn’t dominance affect the fitness of people with the allele? Like wouldn’t dominant embryonic lethal alleles probably be less common than recessive ones?

Interestingly enough i was diagnosed with a radical protein/prion caused cancer when i was 17 and i was allowed to spend time in labs manned by some of the best oncological geneticists in europe; and it was frankly amazing ! I got to study my very own genes beside them, and witness some of the most experimental treatments in oncological in development.

Rabies: I’m the scariest disease ever! Prions: hello :) Rabies: AAAAAAAAAA

I don’t think it’s the scariest outright, but just the fact that it’s relatively common compared to a lot of the other insanely lethal and horrific diseases is enough for it to take the top spot

11:00 is that a Shirakami Fubuki reference ?

I’ve literally never heard of archaea

Hi, does the VA have an ASMR channel?

Is it possible the new alphafold AI could help with this given how little we know about the structure of unhealthily folded prions?

Easy Solution: Don't have sex!

malaria

Food science is so sketchy. There are so few things accounted for you would not accept those kinds of results in any other field its kind of laughable. One clear example would be the countless boogie fat=bad studies from the 70s to the 2000s. Personally, I would not base my diet on any of these studies, specially if they are so case-specific like the effects of kombucha.

Awesome video! Explains prions to even a beginner in microbiology. Pathogenic prions are certainly scary, its a miracle we even discovered them! Astounding work.

I'm mad at myself for missing this stream but hey at least my question made it

This brought me right back to playing Ecco: The tides of time as a kid in ~95. You're lore runs even deeper than that time travelling dolphin.

Tweaking is what you are doing ranking that Worm. A 6/10 is above average but you put it below the average rank and your list.

Dang! Back to the drawing board.

Anytime anyone uses the word "gut" in these contexts I immediately get extremely suspicious

stream starts at 4:58, then a minute of greatings, followed by talking about teaching first question at 9:20

I'm an in-home fitness trainer. Client's dog bit my arm. ER wont take me in because I have no insurance; told me to come back if I have severe pain, oozing or swelling.

The brain otherwise known as soggy bacon.

Wait, cooking doesn't kill prions?, this is bad dude, wait, if prions can make other proteines to fold the wrong way, couldn't another protein make prions fold the right way?, I guess it would be pretty hard to engineer something like that, but if the situation gets bad enough, that maybe a way to fix them.

Technically, rabies is not 100% lethal, even after sympthoms appear. We have a "stunning" 20-40 cases known, when it was survived, mostly from the last say 20 years. Unfortunatelly, Wikipedia says that ~59000 people die PER YEAR, so "some" luck is needed... Moreover, studies showed that there are some unvaccinated individuals with rabies antibodies, i.e. they were infected, but the immune system won without sympthoms. Still, rather don't play with animals having rabies, it's unhealthy... :)

Just found the channel , and love it!!!

1:36:25 hey it's me!

FTIR mentioned, I'm going crazy