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CN Bio
เข้าร่วมเมื่อ 16 พ.ย. 2016
We are a leading Organ-on-a-chip (OOC) company that has developed single- and multi-organ microphysiological systems (MPS) and assays that improve the accuracy and efficiency of drug discovery.
Our PhysioMimix™ OOC lab-benchtop instruments, enable researchers to model human biology in the lab through rapid and predictive 3D human tissue-based studies that harness microfluidic technology. The technology bridges the gap between traditional cell culture and human studies, advancing towards the simulation of human biological conditions to support the accelerated development of new therapeutics.
Our channel is designed to provide you with resources to learn more about OOC and its applications.
Our PhysioMimix™ OOC lab-benchtop instruments, enable researchers to model human biology in the lab through rapid and predictive 3D human tissue-based studies that harness microfluidic technology. The technology bridges the gap between traditional cell culture and human studies, advancing towards the simulation of human biological conditions to support the accelerated development of new therapeutics.
Our channel is designed to provide you with resources to learn more about OOC and its applications.
Introducing our NEW PhysioMimix HT (Higher Throughput)
Introducing the latest microphysiological system in our PhysioMimix™ OOC range - the PhysioMimix™ Single-organ Higher Throughput (HT) System - along with the groundbreaking Multi-chip Liver-48 Plate.
Our next-generation technology overcomes three adoption limitations, cost/chip, throughput and data confidence so that you can benefit from human-relevant insights earlier than ever before.
Through the careful miniaturization of our well-characterized human liver model, which recapitulates its functionality and microarchitecture, the solution facilitates larger-scale yet cost-effective comparative drug screening. Providing 48 chips in one SBS-standard footprint, the Liver-48 plate supports in-plate replicates, controls and 7-point dose responses for data robustness/ reproducibility.
Enabling multi-plate runs per system, this highly scalable solution brings game-changing throughput for predicting human drug safety and efficacy. It can be deployed for a variety of applications, including modeling Non-alcoholic steatohepatitis (NASH), Hepatitis B, drug-induced liver injury and drug metabolism/hepatic clearance.
#organonchip #lifescience #technologynews
Our next-generation technology overcomes three adoption limitations, cost/chip, throughput and data confidence so that you can benefit from human-relevant insights earlier than ever before.
Through the careful miniaturization of our well-characterized human liver model, which recapitulates its functionality and microarchitecture, the solution facilitates larger-scale yet cost-effective comparative drug screening. Providing 48 chips in one SBS-standard footprint, the Liver-48 plate supports in-plate replicates, controls and 7-point dose responses for data robustness/ reproducibility.
Enabling multi-plate runs per system, this highly scalable solution brings game-changing throughput for predicting human drug safety and efficacy. It can be deployed for a variety of applications, including modeling Non-alcoholic steatohepatitis (NASH), Hepatitis B, drug-induced liver injury and drug metabolism/hepatic clearance.
#organonchip #lifescience #technologynews
มุมมอง: 450
วีดีโอ
We are CN Bio - About Us
มุมมอง 5632 ปีที่แล้ว
Ever wondered about what differentiates CN Bio, the people behind our brand, why we come to work every morning or our vision for the future? Here's a snapshot of us in 3 minutes. We hope you enjoy it!
An Introduction to Organ-On-Chip: The Future of Pre-clinical Drug Research
มุมมอง 4652 ปีที่แล้ว
CN Bio Webinar Series 1 - 2020 Current strategies for pre-clinical drug discovery produce potential therapies that fail 90% of the time in clinical trials. To improve this situation, we need new models for research. This webinar will discuss the potentially revolutionary technology behind organ-on-chip systems (OOC). These platforms could improve many aspects of the pre-clinical drug discovery ...
The Scars of Fat: The Transability of 3D NASH Microtissues To Model Human/murine NASH
มุมมอง 1052 ปีที่แล้ว
CN Bio Webinar Series 1 - 2020 Bone Morphogenetic Proteins (BMPs) are members of the TGFβ/BMP superfamily involved in the modulation of hepatic metabolism, liver regeneration, and in the progression of chronic liver disease toward fibrosis and hepatocellular carcinogenesis. This presentation aims to describe the unique role of one of the less studied members of the superfamily, the Bone Morphog...
Go with the Flow: Application of Microfluidic 3D Liver Chip Models for Genotoxity Testing
มุมมอง 1222 ปีที่แล้ว
CN Bio Webinar Series 1 - 2020 Current in vitro pre-clinical genetic toxicology tools used to determine drug metabolism and genotoxicity consist of a metabolic activation system (induced rat S9 mix) and single cells. The low concordance between rat and human metabolism is a potential cause for the low predictive power of rat models for human liver toxicity in clinical trials. This webinar will ...
A Regulators Viewpoint: Strategies to Evaluate Microphysiological Systems for Drug Development
มุมมอง 2172 ปีที่แล้ว
CN Bio Webinar Series 1 - 2020 Microengineered in vitro platforms that enhance the physiology of the cellular microenvironment have been developed and improved in the last decade for modeling focused properties of several tissues or organs, which are not recreated with traditional in vitro cell culture systems. Despite published advancements in modeling tissue physiology in vitro, microphysiolo...
The Rhythm of Life: Using Microfluidics to Mimic Blood Flow. Single and Multi-Organ-on-a-Chip Models
มุมมอง 3002 ปีที่แล้ว
CN Bio Webinar Series 2 - 2020 Microphysiological Systems (MPS), or Organ-on-chip (OOC) technologies, enable researchers to model human biology in the lab via 3D microtissue-based studies. For these advanced 3D in vitro models to realise their potential and remain viable for long periods of time (4 weeks), it is imperative that their culture environments are as “in vivo-like” as possible. One m...
Testing on Humans: Predict Hepatotoxicity and Drug Clearance Ahead of Clinical Trials Using OOC
มุมมอง 1462 ปีที่แล้ว
CN Bio Webinar Series 2 - 2020 Current in vitro approaches for investigational toxicology, drug metabolism (DMPK) and safety are limited and are not fully representative of human response; therefore, drugs showing acceptable preclinical toxicity often fail in human clinical trials, and accurately predicting human drug exposure for new compounds is challenging and costly. Microphysiological Syst...
A Microphysiological Model of Metastatic Progression
มุมมอง 962 ปีที่แล้ว
CN Bio Webinar Series 2 - 2020 In this webinar, we discuss how to use systems to model metastatic progression, evaluate therapeutics and improve our understanding of the bidirectional crosstalk that occurs between host tissue cells and the metastatic cancer cells. Metastatic disease is the leading cause of mortality in patients with solid tumors. Despite decades of research, we only partially u...
Engineering Mucosal Barriers: From Organoids to Organs-on-Chips
มุมมอง 1722 ปีที่แล้ว
CN Bio Webinar Series 2 - 2020 Mucosal barriers are the gateways to all internal organs, serving to transport oxygen, nutrients, and waste and at the same time performing enormous feats of protection against infection and other hazardous insults. The explosion of interest in the human microbiome - especially but not only that in the gut - has driven new interest in building human mucosal barrie...
PhysioMimix™ OOC - Single and multi organ-on-a-chip systems
มุมมอง 2.2K3 ปีที่แล้ว
An introduction to CN Bio's PhysioMimix™ organ-on-a-chip range of single-and multi-organ microphysiological systems. PhysioMimix recreates 3D human organ models in vitro that provide fast, accurate and clinically translatable human data. This animation demonstrates how the PhysioMimix Multi-Organ System enables scientists to reliably and easily interconnect our liver-on-a-chip model with other ...
Introducing the benefits of a human-relevant organ-on-a-chip approach to drug discovery - CN Bio.
มุมมอง 3653 ปีที่แล้ว
Discover the benefits of CN Bio's in vitro organ-on-a-chip (OOC) approach to drug metabolism and toxicology applications. In just 60 seconds, we will explain how the PhysioMimix™ OOC from CN Bio, provides researchers within the pharmaceutical industry with human-relevant and predictive information through the use of advanced single and multi-organ in vitro models and assays.
Predicting the future: humanised drug evaluation testing using organ-on-a-chip technology
มุมมอง 3443 ปีที่แล้ว
CN Bio’s mission is to transform drug discovery through the development of disruptive single and multi-organ microphysiological systems (MPS) -otherwise known as organ-on-a-chip - that optimise the accuracy and efficiency of bringing new medicines to market. This short video will introduce you to: 1) our mission to help improve the accuracy and efficiency of drug discovery by providing research...
How our PhysioMimix system (Organ-on-a-Chip) works
มุมมอง 3.3K4 ปีที่แล้ว
An introduction to the CN Bio Organ On Chip Technology. Our animation walks you through how our "flow" based technology works and the applications its used for. PhysioMimix OOC is the only true open well flow based organ on chip platform. for more information goto: www.cn-bio.com Simple to use Adapts to your research needs Generates clinically translatable data For optimal viewing, please ensur...
5 Minute Guide to Human Organ-on-Chip Studies: Cells, Tissues, Organs and Multi-Organ Experiments
มุมมอง 20K5 ปีที่แล้ว
PhysioMimix Organ-on-Chip allows you to model human biology in the lab. As a microphysiological system, it can be used to culture healthy or diseased tissue models, study multi-organ interactions and investigate ADME and toxicity.
Organ-on-Chip Studies Workflow (6/6) Set Up Protocol for PhysioMimix OOC from CN Bio
มุมมอง 1255 ปีที่แล้ว
Organ-on-Chip Studies Workflow (6/6) Set Up Protocol for PhysioMimix OOC from CN Bio
Organ-on-Chip Studies Workflow (5/6) Multi-Organ Analysis with PhysioMimix OOC from CN Bio
มุมมอง 1305 ปีที่แล้ว
Organ-on-Chip Studies Workflow (5/6) Multi-Organ Analysis with PhysioMimix OOC from CN Bio
Organ-on-Chip Studies Workflow (4/6) Analysis with PhysioMimix OOC from CN Bio
มุมมอง 965 ปีที่แล้ว
Organ-on-Chip Studies Workflow (4/6) Analysis with PhysioMimix OOC from CN Bio
Organ-on-Chip Studies Workflow (3/6) Dosing with PhysioMimix OOC from CN Bio
มุมมอง 965 ปีที่แล้ว
Organ-on-Chip Studies Workflow (3/6) Dosing with PhysioMimix OOC from CN Bio
Organ-on-Chip Studies Workflow (2/6) Cell Culture with PhysioMimix OOC from CN Bio
มุมมอง 985 ปีที่แล้ว
Organ-on-Chip Studies Workflow (2/6) Cell Culture with PhysioMimix OOC from CN Bio
Organ-on-Chip Studies Workflow (1/6): PhysioMimix OOC from CN Bio
มุมมอง 1695 ปีที่แล้ว
Organ-on-Chip Studies Workflow (1/6): PhysioMimix OOC from CN Bio
Organ-on-Chip Studies with Physiomimix OOC from CNBio (60 second walkthrough)
มุมมอง 1175 ปีที่แล้ว
Organ-on-Chip Studies with Physiomimix OOC from CNBio (60 second walkthrough)
Benchtop Organ-on-Chip Device: Physiomimix from CNBio (60 second walkthrough)
มุมมอง 7946 ปีที่แล้ว
Benchtop Organ-on-Chip Device: Physiomimix from CNBio (60 second walkthrough)
Organ-on-Chip Studies Workflow (2/6) Cell Culture with PhysioMimix T1 from CN Bio
มุมมอง 9746 ปีที่แล้ว
Organ-on-Chip Studies Workflow (2/6) Cell Culture with PhysioMimix T1 from CN Bio
Organ-on-Chip Studies Workflow (3/6) Dosing with PhysioMimix T1 from CN Bio
มุมมอง 8056 ปีที่แล้ว
Organ-on-Chip Studies Workflow (3/6) Dosing with PhysioMimix T1 from CN Bio
Organ-on-Chip Studies Workflow (4/6) Analysis with PhysioMimix T1 from CN Bi
มุมมอง 7666 ปีที่แล้ว
Organ-on-Chip Studies Workflow (4/6) Analysis with PhysioMimix T1 from CN Bi
Organ-on-Chip Studies Workflow (5/6) Multi-Organ Analysis with PhysioMimix T1 from CN Bio
มุมมอง 8266 ปีที่แล้ว
Organ-on-Chip Studies Workflow (5/6) Multi-Organ Analysis with PhysioMimix T1 from CN Bio
Organ-on-Chip Studies Workflow (6/6) Set Up Protocol for PhysioMimix T1 from CN Bio
มุมมอง 6376 ปีที่แล้ว
Organ-on-Chip Studies Workflow (6/6) Set Up Protocol for PhysioMimix T1 from CN Bio
Organ-on-Chip Studies Workflow Walk-Through (1/6): PhysioMimix T1 from CN Bio
มุมมอง 1.3K6 ปีที่แล้ว
Organ-on-Chip Studies Workflow Walk-Through (1/6): PhysioMimix T1 from CN Bio
WEBINAR: Organ on a Chip: Improving Preclinical Studies for Faster Drug Development
มุมมอง 2.4K6 ปีที่แล้ว
WEBINAR: Organ on a Chip: Improving Preclinical Studies for Faster Drug Development
Good morning 🌄
Please also work on urethral stricture deaseas
Please give relief after OIU dilation patient I will pray for you
Please work on development of human urethra transplant without uroplasty place in between effected part of urethra which is elastable only this was created by high brain genetic scientist nothing is impossible everything is possible please work on this issue and save life god bless you hope you are try to create advancement of urethral stricture treatment or tissues re engineering technique
Ss Германии
First class in lab technologies!!!🌎🌍🌏🙋🏻♀️👏♾️Dra Ethel Mediza Madera PHD, SURGEON CONSULTANT TREATMENT Science investgations.Ahead!!!
My best dream ⚕️😍😷
Is possibile build human horgan whit nanotecnology medicine?tx
Good morning is possibile kill cancer or infections whit nanotecnology medicine +5G? Or build human horgan? Tx
👏