วีดีโอ

Thank you sir dor these video its highly helpful for last min revision🎉🎉

Thank you sir dor these video its highly helpful for last min revision🎉🎉

Vignesh s

So proud of you for the Gratitude and wonderful Contributions for learner’s Dear Dr Soundarya -

Shazmeen fazeela

Shazmeen fazeela

Shazmeen fazeela

A good class🎉

Hey

K.Amrita

Rojah Islam

Great lecture👌

Nitish Kumar G

Vansh Bhardwaj

🎉🎉

Medusane - Diabetes Day 2024 Answers for questions asked by the audience Dr Jagadish R, Associate Professor, Velammal Medical College, Madurai (For further queries: iamjagankmr@gmail.com) Q1. What are the antibodies in DM? • Anti-Glutamic acid decarboxylase antibodies (Anti-GAD) • Anti-inuslin antibodies (anti- IAA) • Anti-Islet -2A (Anti-IA2A) • Anti- islet cell cytoplasmic antibodies (anti- ICA) • Anti -ZnT8 (Anti-Znt8) The presence of multiple insulin antibodies (GAD, IA-2, IAA, ICA, and ZnT8) is predictive of T1DM Q2. Wasting is a feature of DM (due to increased protein catabolism in state of starvation), however I rarely see weight loss in real life. • Wasting or loss of muscle mass usually result from imbalance between synthesis and degradation of muscle protein • Weight loss due to muscle wasting may be clearly evident in diabetes as there is co-existing obesity (increase in fat mass). This is called as Sarcopenic obesity (i.e.), a condition in which loss of muscle mass is not recognised due to excess body weight caused by obesity. • Lean body mass (Body weight - Fat weight) is essential for peripheral glucose uptake. Q3.Type 2 DM present with dyslipidemia with metabolic syndrome, which may result in obesity. However insulin resistance should prevent deposition of fat? (since it is the action of insulin) Insulin resistance leads to increase in VLDL due to excess formation of triglycerides in liver. Explain. • Insulin is a lipogenic hormone (stimulates synthesis of triacylglycerol, which is stored in adipose tissue, liver and other tissues) • In case of insulin resistance, lipolysis i.e. breakdown of TAG occur in adipose tissue resulting in the release of non-esterified fatty acids (NEFA) • This increase in NEFA will be taken up by liver and converted to triglyceride, leading to increase in very low density lipoprotein (VLDL). • Clearance of VLDL is impaired in DM , which further augments its increase • Increase in VLDL - lead to increase in LDL and decrease in HDL , hence there is dyslipidemia. • Q4. Can autoimmune insulin mediated diabetes resolve spontaneously? No, it does not resolve spontaneously and requires follow up and monitoring at regular intervals. There is often a temporary period of improved beta cell function lasting for 6-24 months. Subsequently, beta cell function will deteriorate and require support. Q5. Is MODY treatment conservative? Management of MODY depends upon its subtype, and its treatment options include diet, oral anti-diabetic drugs or insulin (Nkonge et al., 2020) References: David B. Wile, John P.H. Wilding, CHAPTER 15 - Glucose metabolism and the pathophysiology of diabetes mellitus, Clinical Biochemistry: Metabolic and Clinical Aspects (Third Edition),doi.org/10.1016/B978-0-7020-5140-1.00015-8. Nkonge, K.M et al, The epidemiology, molecular pathogenesis, diagnosis, and treatment of maturity-onset diabetes of the young (MODY). Clin Diabetes Endocrinol(2020). doi.org/10.1186/s40842-020-00112-5 Lopez-Pedrosa et al., . The Vicious Cycle of Type 2 Diabetes Mellitus and Skeletal Muscle Atrophy: Clinical, Biochemical, and Nutritional Bases. Nutrients 2024, doi.org/10.3390/nu16010172

For any queries, Please contact sir through the mail given below! Dr Jagadish R, Associate Professor, Velammal Medical College, Madurai (For further queries: iamjagankmr@gmail.com)

Very nice Presentation sir ,Explain very well sir .

One of the greatest professors i was blessed enough to witness teaching... Thank you sir...

Vansh Bhardwaj, I was unable to attend the live so I am watching the recorded version

Learnt a lot of new guidelines from sir class. Many more classes like this in future.

Just for clarity sake, isn’t the Wernickes area located in the temporal lobe?

Informative class on the most needed topic 🙏🙏

Great initiative kudos team medusane 🫡

Wow manthra #proud

Amazing manthra...keep going🔥🔥

Where do you all find these professors? They're really good

The lecture was nice and understandable thank you sir

🎉🎉👌👌

It was nice session sir

palpatory findings in AS????

HR *STROKE VOLUME =CO

CO=STROKE VOLUME *STROKE VOLUME NOT the STROKE VOLUME RESISTANCE?????

This is very elaborate, thanks a lot Doctor. From Uganda

Thank you very much sir for the wonderful explanation, finally I understood this topic😊😊

Please continue to make class Mam please

Madam your way of teaching is fantastic n easy to understand ❤

5:28 class starts

🎉🎉🎉❤❤Thank you so much sir

1:17:45 face demonstration

1:07:13 breech demonstrations

45:05 occiputo posterior demonstratio

20:12 normal mechanism of labour

13:40 demonstrations

44:18 pelvis

12:06 fetal skull

Very very nice

Excellent session team

Non clinical subjects faculty requirement reduced by 30 per😮cent😢 ...

Mam what is meant by overriding of aorta ???…………….. ..?.?….