Metabolism Made Easy
Metabolism Made Easy
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Catabolism of Amino Acids: Role of Transaminases @Metabolism Made Easy
Catabolism of amino acids typically begins by the removal of the amine group by transaminases producing the corresponding keto acids from their respective amino acids. Alanine transaminase (ALT) and aspartate transaminase (AST) are important liver enzymes required for the catabolism of alanine and glutamate, respectively. All transaminases are reversible and can proceed in either direction and require Vitamin B6 as a coenzyme.
มุมมอง: 16

วีดีโอ

Catabolism of Amino Acids: An Overview @Metabolism Made Easy
มุมมอง 2014 วันที่ผ่านมา
Amino acids are catabolized to remove their nitrogen by transaminases. This reaction transfers an amine group from an amino acid to an acceptor keto acid, producing a new amino acid in the process. Alpha-ketoglutarate is an important keto acid acceptor molecule that can be converted to glutamate upon accepting an amino group from specific amino acids. Glutamate can be considered therefore as th...
Misconceptions About Glucose: Hormonal Regulation of Plasma Glucose @Metabolism Made Easy
มุมมอง 2928 วันที่ผ่านมา
This podcast clarifies some misconceptions about glucose metabolism. Glucose is an essential energy source for various tissues and cells and is maintained at a certain level in the bloodstream through the concerted action of various hormones. When these hormones are functioning properly, they regulate glucose in the bloodstream and prevent spikes in glucose, as well as significant drops in gluc...
Catabolism of Alanine, Glutamate, and Aspartate @Metabolism Made Easy
มุมมอง 37หลายเดือนก่อน
This podcast covers the catabolism of alanine, glutamate, and aspartate by alanine transaminase, glutamate dehydrogenase, and aspartate transaminase, respectively. These three enzymes play a key role in the overall metabolism of amino acids. Glutamate, in particular, is the sink (collector) of nitrogen from many amino acids and will ultimately provide the ammonia that can enter the urea cycle. ...
Cell-Cell Communication @ Metabolism Made Easy
มุมมอง 47หลายเดือนก่อน
Cell-Cell Communication is a fundamental process that is essential for the regulation of metabolism in various organs. Through hormones of the endocrine system, signals are chemically transmitted through the bloostream between different organs. The outcome of a hormone binding its specific receptor in target tissues can produce profound effects on metabolism. Insulin and its effects on the live...
Creating & Organizing a Grant Proposal @Metabolism Made Easy
มุมมอง 11หลายเดือนก่อน
This podcast describes in some detail the development of a research grant proposal in the life sciences/biological sciences. Structuring and organizing the proposal is based on creating several sections within the grant: 1) Specific Aims; 2) Background & Significance; 3) Preliminary Studies; 4) Experimental Design; 5) Literature Cited; and 6) Appendix.
Creating an Effective Presentation: Perspective of a Research Scientist @ Metabolism Made Easy
มุมมอง 10หลายเดือนก่อน
This podcast covers the key components for creating an effective presentation. These include 1) preparation; 2) learning objectives; 3) organization, and 4) summary. Three other components contribute to the retention of information. Those are attention, meaning, and emotion.
Metabolism: An Overview @Metabolism Made Easy
มุมมอง 25หลายเดือนก่อน
This podcast is an overview of metabolism which includes: 1) definition; 2) compartments; 3) major cellular uses of glucose, amino acids, and fat; 4) the major hormones that regulate metabolism , and 5) a summary of tissue metabolism in the well-fed and fasting states.
Epinephrine & Plasma Fatty Acids @ Metabolism Made Easy
มุมมอง 242 หลายเดือนก่อน
Epinephrine & Plasma Fatty Acids @ Metabolism Made Easy
Glucose Metabolism: 4 Pathways @Metabolism Made Easy
มุมมอง 432 หลายเดือนก่อน
Glucose Metabolism: 4 Pathways @Metabolism Made Easy
Misconceptions About Glucose @Metabolism Made Easy
มุมมอง 252 หลายเดือนก่อน
Misconceptions About Glucose @Metabolism Made Easy
3 Misconceptions About Dietary Fat @ Metabolism Made Easy
มุมมอง 333 หลายเดือนก่อน
3 Misconceptions About Dietary Fat @ Metabolism Made Easy
Regulation of Glycolysis & Gluconeogenesis: A Summary @Metabolism Made Easy
มุมมอง 363 หลายเดือนก่อน
Regulation of Glycolysis & Gluconeogenesis: A Summary @Metabolism Made Easy
Metabolic Misconceptions About Dietary Protein @Metabolism Made Easy
มุมมอง 203 หลายเดือนก่อน
Metabolic Misconceptions About Dietary Protein @Metabolism Made Easy
Amino Acids Catabolism: An Inefficient Energy Source @Metabolism Made Easy
มุมมอง 193 หลายเดือนก่อน
Amino Acids Catabolism: An Inefficient Energy Source @Metabolism Made Easy
Glucose Transporters @Metabolism Made Easy
มุมมอง 444 หลายเดือนก่อน
Glucose Transporters @Metabolism Made Easy
PKA & Inhibition of Glycolysis @Metabolism Made Easy
มุมมอง 244 หลายเดือนก่อน
PKA & Inhibition of Glycolysis @Metabolism Made Easy
Red Blood Cells & Glucose Metabolism @Metabolism Made Easy
มุมมอง 214 หลายเดือนก่อน
Red Blood Cells & Glucose Metabolism @Metabolism Made Easy
ATP Output from Glucose, Palmitate & Acetoacetate Catabolism @Metabolism Made Easy
มุมมอง 485 หลายเดือนก่อน
ATP Output from Glucose, Palmitate & Acetoacetate Catabolism @Metabolism Made Easy
cAMP Phosphodiesterase & Adenylate Cyclase @Metabolism Made Easy
มุมมอง 655 หลายเดือนก่อน
cAMP Phosphodiesterase & Adenylate Cyclase @Metabolism Made Easy
The Muscle & Liver Gluconeogenesis @Metabolism Made Easy
มุมมอง 305 หลายเดือนก่อน
The Muscle & Liver Gluconeogenesis @Metabolism Made Easy
Hormonal Regulation of Metabolism in a Nutshell @Metabolism Made Easy
มุมมอง 825 หลายเดือนก่อน
Hormonal Regulation of Metabolism in a Nutshell @Metabolism Made Easy
Glucose & The Liver-Brain Connection @Metabolism Made Easy
มุมมอง 375 หลายเดือนก่อน
Glucose & The Liver-Brain Connection @Metabolism Made Easy
Termination of cAMP Effects @Metabolism Made Easy
มุมมอง 325 หลายเดือนก่อน
Termination of cAMP Effects @Metabolism Made Easy
Cellular Roles of Nucleotides @Metabolism Made Easy
มุมมอง 135 หลายเดือนก่อน
Cellular Roles of Nucleotides @Metabolism Made Easy
Integration of Metabolism II: A Summary of Tissue Effects @Metabolism Made Easy
มุมมอง 236 หลายเดือนก่อน
Integration of Metabolism II: A Summary of Tissue Effects @Metabolism Made Easy
Purine Salvage Pathway & Enzymes @ Metabolism Made Easy
มุมมอง 176 หลายเดือนก่อน
Purine Salvage Pathway & Enzymes @ Metabolism Made Easy
Glucagon & Epinephrine Effects on Carbohydrate & Lipid Metabolism @Metabolism Made Easy
มุมมอง 596 หลายเดือนก่อน
Glucagon & Epinephrine Effects on Carbohydrate & Lipid Metabolism @Metabolism Made Easy
Glucose & Insulin Secretion by The Pancreas @Metabolism Made Easy
มุมมอง 606 หลายเดือนก่อน
Glucose & Insulin Secretion by The Pancreas @Metabolism Made Easy
Regulation & Integration of Metabolism I : An Overview @Metabolism Made Easy
มุมมอง 296 หลายเดือนก่อน
Regulation & Integration of Metabolism I : An Overview @Metabolism Made Easy

ความคิดเห็น

  • @jaym9846
    @jaym9846 18 วันที่ผ่านมา

    Interesting. Citrate is also an important factor in calculating Dr. William Cromwell's Metabolic Vulnerability Index (MVX) for cardiovasular events. Can excess citrate be measured in blood?

    • @DrAJGhalayini
      @DrAJGhalayini 18 วันที่ผ่านมา

      I suspect it can. The effects mentioned on metabolism are typically intracellular (inside the liver). It's unclear if there is a correlation between intracellular and plasma concentrations of citrate.

  • @augurcybernaut4785
    @augurcybernaut4785 2 หลายเดือนก่อน

    I can’t work out if oral supplements of reduced glutathione is what G6PD deficiency needs

    • @DrAJGhalayini
      @DrAJGhalayini 2 หลายเดือนก่อน

      In general, an inherted enzyme deficiency typically can not be restored/ reversed by supplementing with a coenzyme (Glutathione).

    • @augurcybernaut4785
      @augurcybernaut4785 2 หลายเดือนก่อน

      @@DrAJGhalayini I wish I new what markers or blood test to ask for to assess the state of my G6PD.

    • @DrAJGhalayini
      @DrAJGhalayini 2 หลายเดือนก่อน

      I believe there is a specific G6PD blood test that your doctor could request. Please consult with your doctor.

  • @rajeshdalvi-md4yu
    @rajeshdalvi-md4yu 4 หลายเดือนก่อน

    Thank you very much

    • @DrAJGhalayini
      @DrAJGhalayini 4 หลายเดือนก่อน

      You are welcome

  • @DrAJGhalayini
    @DrAJGhalayini 4 หลายเดือนก่อน

    Thanks.

  • @nidanazsujjad2076
    @nidanazsujjad2076 4 หลายเดือนก่อน

    Good 👍🏼

  • @jothirmuniyasamy9910
    @jothirmuniyasamy9910 4 หลายเดือนก่อน

    Thanks

    • @DrAJGhalayini
      @DrAJGhalayini 4 หลายเดือนก่อน

      You're welcome.

  • @DrAJGhalayini
    @DrAJGhalayini 5 หลายเดือนก่อน

    You're welcome.

  • @عامرأحمد-ث1ذ
    @عامرأحمد-ث1ذ 5 หลายเดือนก่อน

    thanks for the information

  • @michaelsrowland
    @michaelsrowland 6 หลายเดือนก่อน

    What is a receptor?

    • @DrAJGhalayini
      @DrAJGhalayini 6 หลายเดือนก่อน

      A receptor is a protein embedded in the cell membrane and is in contact with the extracellular matrix. It will specifically bind certain hormones and communicates the information to the cell's interior, thus generating a cellular response.

  • @Alex46587
    @Alex46587 7 หลายเดือนก่อน

    Only teaching by Slides is effective

    • @DrAJGhalayini
      @DrAJGhalayini 7 หลายเดือนก่อน

      Thank you for your comment. Learning is a personal journey. Everyone finds their own preferred method. One size does not fit all!

    • @Alex46587
      @Alex46587 7 หลายเดือนก่อน

      @@DrAJGhalayini I have 21,900 hours of learning experience in youtube

    • @DrAJGhalayini
      @DrAJGhalayini 7 หลายเดือนก่อน

      I have taught biochemistry to 15000 medical and premedical students between 2004-2020.

    • @Alex46587
      @Alex46587 7 หลายเดือนก่อน

      @@DrAJGhalayini Clear explanations, helpful content. Great biochemistry resource. Thank you for your valuable contribution.

    • @DrAJGhalayini
      @DrAJGhalayini 7 หลายเดือนก่อน

      Thank you.

  • @jamesgordon8867
    @jamesgordon8867 8 หลายเดือนก่อน

    Sir, I am trying my best to understand the role of insulin and diabetes. I have heard more than one person mention that exercise improved blood sugar values. And this is true. The more muscle tone and mass I get the better the insulin levels improved. I only went up to Organic chem. I want desperately learn. Please help me understand how I got to an A1C of 5.1, blood sugars with a 90 of106, with lower carbs, less meds. When I exercise, it's the only way to get better health. You understand all this. I have heard more than one person state muscles are the only thing that doesn't need insulin to get glucose into the cells as long as you exercise. What am I missing?

    • @jamesgordon8867
      @jamesgordon8867 8 หลายเดือนก่อน

      I had 400 after exercise a few years ago, to see 90 day average of 106 is astounding to me. Just trying to know like I did when I was a Respiratory Therapist and understood enough to keep people breathing.

    • @DrAJGhalayini
      @DrAJGhalayini 8 หลายเดือนก่อน

      The last statement about the muscle and insulin is completely false. In fact, insulin helps the muscle, and adipose tissue pick up more glucose after a meal from the bloodstream. Thus reducing blood glucose after a meal. Muscle and adipose tissue account for a significant portion of body mass so they both can reduce blood glucose significantly. This happens regardless of exercise. The effect of insulin on glucose uptake by these two tissues is highly specific for muscle and adipose tissue. Insulin, blood glucose, and diabetes are quite complex topics to adequately discuss here.

  • @jamesgordon8867
    @jamesgordon8867 8 หลายเดือนก่อน

    If muscles don't need insulin, please explain the role of insulin

    • @DrAJGhalayini
      @DrAJGhalayini 8 หลายเดือนก่อน

      I am not sure where you got that concept from? Muscle metabolism, just like the liver and many other tissues, is profoundly affected by insulin. The key effects in muscle are increased: 1. Glycogen synthesis 2. Glucose uptake. 3. Protein synthesis Check out the video below for more details: th-cam.com/video/8wOJtHxa-4E/w-d-xo.html

  • @solomonasresahgn7576
    @solomonasresahgn7576 9 หลายเดือนก่อน

    Nice presentation

  • @snakejuce
    @snakejuce 9 หลายเดือนก่อน

    Appreciate you for doing these doc. I have a small favor to ask, is it possible to NOT add music soundtrack? I cannot hear your voice in some parts and have to turn up the volume, and then it gets annoying. I wish it was just normal voice, no music 😅. Of course, it's up to you, just my opinion. Take care, just discovered this amazing channel.

    • @DrAJGhalayini
      @DrAJGhalayini 9 หลายเดือนก่อน

      Thanks for your input.

  • @عامرأحمد-ث1ذ
    @عامرأحمد-ث1ذ 9 หลายเดือนก่อน

    Thank you doctor for the important information

    • @DrAJGhalayini
      @DrAJGhalayini 9 หลายเดือนก่อน

      You are welcome.

  • @عامرأحمد-ث1ذ
    @عامرأحمد-ث1ذ 9 หลายเดือนก่อน

    Thank you doctor for the important information

    • @DrAJGhalayini
      @DrAJGhalayini 9 หลายเดือนก่อน

      You are welcome.

  • @Sithu-1112
    @Sithu-1112 9 หลายเดือนก่อน

    This was the thing which I was exactly looking for..Thank you very much sir❤

    • @DrAJGhalayini
      @DrAJGhalayini 9 หลายเดือนก่อน

      Glad to hear.

  • @shinn-tyanwu4155
    @shinn-tyanwu4155 10 หลายเดือนก่อน

    Thanks 😊😊😊

  • @mohammadalam7536
    @mohammadalam7536 ปีที่แล้ว

    Lovely

  • @Rahulpandey-lm4rv
    @Rahulpandey-lm4rv ปีที่แล้ว

    hi sir

    • @DrAJGhalayini
      @DrAJGhalayini ปีที่แล้ว

      Hello

    • @Rahulpandey-lm4rv
      @Rahulpandey-lm4rv ปีที่แล้ว

      @@DrAJGhalayini saw your videos... very educational..👌👌👍

    • @Rahulpandey-lm4rv
      @Rahulpandey-lm4rv ปีที่แล้ว

      loved your content 🙏🙏

    • @DrAJGhalayini
      @DrAJGhalayini ปีที่แล้ว

      @@Rahulpandey-lm4rv Thank you. I'm glad you like the content.

  • @mohammadalam7536
    @mohammadalam7536 ปีที่แล้ว

    Lovely. Looking forward to seeing more of biochemical pathways.

  • @burakozvit7480
    @burakozvit7480 ปีที่แล้ว

    Amazing 👏 Thanks Sir ❤👍

  • @iantoyota007
    @iantoyota007 ปีที่แล้ว

    Great video, Thanks

  • @gauravdesale9552
    @gauravdesale9552 ปีที่แล้ว

    Wow this simulation is intricate

  • @jean_yves_plongeur
    @jean_yves_plongeur ปีที่แล้ว

    I agree but you also could comfortably start with a 480W belt sander for this type of work.

    • @DrAJGhalayini
      @DrAJGhalayini ปีที่แล้ว

      This content is about the metabolism of cholesterol and its control. It is intended for students who are genuinely interested in the topic.

  • @chellemorante3220
    @chellemorante3220 ปีที่แล้ว

    Thank you!

  • @angelic7886
    @angelic7886 2 ปีที่แล้ว

    Thank you. Have an exam on this tomorrow :(

  • @malvinderkaur541
    @malvinderkaur541 2 ปีที่แล้ว

    all this fine but i wish nutrition studies now really release the list of foods as to what produces what in our bodies which food groups produces more toxic build up like urea or which foods carry good amino acids for cellular molecular health and very important chart to have, i know for sure eating meats do create lot of urea protein build ups, larger heavier the meats like beef more of it builds up lighter the meat less it is like fish, yet what is there in groups of vegetables grains fruits etc... what all do we get and at what percentage...

    • @DrAJGhalayini
      @DrAJGhalayini 2 ปีที่แล้ว

      To clarify, Urea is NOT toxic, it is released in the bloodstream and excreted by the kidney. Ammonia ( NH3) on the other hand, is toxic. The function of the Urea cycle is to remove and prevent the buildup of ammonia in tissues and dispose of it in the non-toxic form, urea. Protein-rich foods will produce more Urea which will be excreted by the kidney. You might be thinking of Uric acid. The latter molecule is produced from degradation of nucleotides. Excess Uric acid is associated with gout and results in arthritic pain in the joints.

  • @chelsaepavese8275
    @chelsaepavese8275 2 ปีที่แล้ว

    ☝️ pr໐๓໐Ş๓

  • @marttyd
    @marttyd 2 ปีที่แล้ว

    Thanks. Triglycerides?

  • @marttyd
    @marttyd 2 ปีที่แล้ว

    What is TAG?

    • @DrAJGhalayini
      @DrAJGhalayini 2 ปีที่แล้ว

      TAG is short for Triacylglycerol, the major storage form of fat in adipose tissue.

  • @george2468
    @george2468 2 ปีที่แล้ว

    Dr. G from SGU!!

  • @dammytesucun2846
    @dammytesucun2846 3 ปีที่แล้ว

    By far, the best professor!