Vyvyane Loh, MD
Vyvyane Loh, MD
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How does Iron get into cells ?
How does Iron get into cells ?
มุมมอง: 68

วีดีโอ

What is a Free Radical?
มุมมอง 753 หลายเดือนก่อน
What is a Free Radical?
The Fenton Reaction
มุมมอง 1083 หลายเดือนก่อน
The Fenton Reaction
Iron’s Function in the Human Body
มุมมอง 494 หลายเดือนก่อน
Iron’s Function in the Human Body
Episode 54: Life & Death with Iron
มุมมอง 1804 หลายเดือนก่อน
Episode 54: Life & Death with Iron
Episode 55: Physician Burnout--How the Cult of Medicine Traps Doctors
มุมมอง 3224 หลายเดือนก่อน
Episode 55: Physician Burnout How the Cult of Medicine Traps Doctors
8. TD and manifestations of apoB
มุมมอง 958 หลายเดือนก่อน
8. TD and manifestations of apoB
3. TD: "All cells make cholesterol."
มุมมอง 918 หลายเดือนก่อน
3. TD: "All cells make cholesterol."
1. TD's unique views on Phospholipids
มุมมอง 798 หลายเดือนก่อน
1. TD's unique views on Phospholipids
5. TD: Statins prefer Liver
มุมมอง 528 หลายเดือนก่อน
5. TD: Statins prefer Liver
4. TD: The Lipoproteins did it!
มุมมอง 458 หลายเดือนก่อน
4. TD: The Lipoproteins did it!
7. TD and cholesterol's purpose in lipoproteins
มุมมอง 578 หลายเดือนก่อน
7. TD and cholesterol's purpose in lipoproteins
6. TD: "There is no cholesterol metabolism."
มุมมอง 418 หลายเดือนก่อน
6. TD: "There is no cholesterol metabolism."
Episode 53: Reviewing Dayspring and Attia
มุมมอง 1.5K8 หลายเดือนก่อน
Episode 53: Reviewing Dayspring and Attia
2. TD redefines Lipid Rafts
มุมมอง 328 หลายเดือนก่อน
2. TD redefines Lipid Rafts
Why Tuberculosis & Atherosclerosis are Siblings! | Episode 52
มุมมอง 195ปีที่แล้ว
Why Tuberculosis & Atherosclerosis are Siblings! | Episode 52
Vascular Calcification The Real Story | Episode 51
มุมมอง 532ปีที่แล้ว
Vascular Calcification The Real Story | Episode 51
Macrophages in the Plaque What No one Told You | Episode 50
มุมมอง 182ปีที่แล้ว
Macrophages in the Plaque What No one Told You | Episode 50
Accelerated Muscle Loss: What is Cachexia?
มุมมอง 581ปีที่แล้ว
Accelerated Muscle Loss: What is Cachexia?
What's Really Important About the Vasa Vasorum | Episode 49
มุมมอง 263ปีที่แล้ว
What's Really Important About the Vasa Vasorum | Episode 49
What They Got Wrong About The Vasa Vasorum | Episode 48
มุมมอง 300ปีที่แล้ว
What They Got Wrong About The Vasa Vasorum | Episode 48
The Clot Thickens in Atherosclerosis but How?
มุมมอง 1.1Kปีที่แล้ว
The Clot Thickens in Atherosclerosis but How?
Cholesterol's Secret Role in Atherosclerosis | Episode 46
มุมมอง 468ปีที่แล้ว
Cholesterol's Secret Role in Atherosclerosis | Episode 46
The Missing Link Between LDL & Atherosclerosis | Episode 45
มุมมอง 992ปีที่แล้ว
The Missing Link Between LDL & Atherosclerosis | Episode 45
Catabolism vs Anabolism Explained
มุมมอง 43ปีที่แล้ว
Catabolism vs Anabolism Explained
Why You Should Drink Tea | Episode 44
มุมมอง 123ปีที่แล้ว
Why You Should Drink Tea | Episode 44
What is SARCOPENIA?
มุมมอง 94ปีที่แล้ว
What is SARCOPENIA?
Sleep and Athletic Performance | Episode 43
มุมมอง 68ปีที่แล้ว
Sleep and Athletic Performance | Episode 43
Estrogen and the Munchies?!
มุมมอง 105ปีที่แล้ว
Estrogen and the Munchies?!
Is Ginger Good for You? | Episode 42
มุมมอง 181ปีที่แล้ว
Is Ginger Good for You? | Episode 42

ความคิดเห็น

  • @TheChargerJeff
    @TheChargerJeff 4 วันที่ผ่านมา

    I think The Free Radicals would make a helluva name for a punk band.

    • @vlmdrounds
      @vlmdrounds 8 ชั่วโมงที่ผ่านมา

      Agreed! And maybe they should open for the Antioxidants!

  • @paulhart3812
    @paulhart3812 8 วันที่ผ่านมา

    Why is it so difficult to just eliminate lead and cadmium from the production process? Surely SOMEONE can do it. It might be expensive, but people will pay a premium to have chocolate that’s free of heavy metals.

    • @vlmdrounds
      @vlmdrounds 6 วันที่ผ่านมา

      I agree that where there's a will, there's a way. I don't know the costs involved but there might be a business case for a motivated entrepreneur...

  • @VincentRenata-v4g
    @VincentRenata-v4g 11 วันที่ผ่านมา

    Yundt Spur

  • @virtualoutburst6873
    @virtualoutburst6873 13 วันที่ผ่านมา

    Thank you for this episode 😊 there was a lot to take in. As a man in my 40s, I’ve been taking natural aromatic, inhibitor supplements such as salt, Palmetto, and stinging nettle for prostate health and hair growth. Should I go off of these? It concerns me now?

    • @vlmdrounds
      @vlmdrounds 6 วันที่ผ่านมา

      @virtualoutburst6873 Technically, saw palmetto and stinging nettle do have anti-estrogenic effects. It is hard to gauge the net hormonal effects in an individual so I can understand your dilemma. I don't know where you are located but it really would be best to consult a doctor skilled in hormone therapy.

  • @pauladdae3130
    @pauladdae3130 21 วันที่ผ่านมา

    Some brands have lower amounts of lead and cadmium and hence are better choices. Such as some dark chocolate products from: Ghirardelli, Mast, Taza and Valrhona (Abinao 85%). These are not easy to get in the UK though, apart from the latter. Not sure about Hu or Montezuma. However, both have published details stating that the levels in their products are acceptable according to EU standards - yet those levels are still very high. The bog standard dark chocolates in the large supermarket chains may have larger amounts.

    • @vlmdrounds
      @vlmdrounds 20 วันที่ผ่านมา

      Yes, thank you. It's a good idea to try to get the brands that have lower contamination levels. Would be nice though, if we never had this problem in the first place...

  • @cautioushubbard3074
    @cautioushubbard3074 23 วันที่ผ่านมา

    There's a 1000 videos on cadmium none to help solve problem

    • @vlmdrounds
      @vlmdrounds 23 วันที่ผ่านมา

      Yes, there is no perfect solution, unfortunately. However, if you love chocolate, try going to 15:10 and 31:39

  • @GeoffreyDick-u4n
    @GeoffreyDick-u4n 24 วันที่ผ่านมา

    Darrel Locks

  • @sandyschafer2895
    @sandyschafer2895 24 วันที่ผ่านมา

    How do I get rid of a lot of body fat without losing weight? I have a lot of fat and high cholesterol but I have a normal BMI

    • @vlmdrounds
      @vlmdrounds 24 วันที่ผ่านมา

      Yes, a very good question. Most doctors would look at your BMI and be satisfied with that but getting rid of excess body fat regardless of BMI is important to preserving your health. It involves detailed attention to nutrition (making sure you get enough protein--I get my clients to eat 4-5 times a day!), sleep (poor sleep/not enough sleep affects your metabolism negatively) and prioritizing resistance training (plus metabolic conditioning which I also find very effective for my clients) for more muscle. When done right you should see changes within 3 months.

    • @sandyschafer2895
      @sandyschafer2895 21 วันที่ผ่านมา

      @@vlmdrounds thanks

  • @KORTOKtheSTRONG
    @KORTOKtheSTRONG หลายเดือนก่อน

    🍊

  • @KORTOKtheSTRONG
    @KORTOKtheSTRONG หลายเดือนก่อน

    neat

  • @CondorAHLS
    @CondorAHLS หลายเดือนก่อน

    Great usable information and thoroughly and excellently presented. Ok, I guess I am now done consuming dark chocolate for cognitive function benefits. I’ll stick to just hard cardio, healthy diet, and reading.

    • @vlmdrounds
      @vlmdrounds หลายเดือนก่อน

      I hope you'e not a chocolate lover! I am more of a vanilla fan so it's not such a sacrifice...

  • @JohnnyBoy-c4b
    @JohnnyBoy-c4b หลายเดือนก่อน

    Informative. Thank you! Could you talk about the benefits of consuming chocolate so that I can make an informed decision about whether or not to eat it?

    • @vlmdrounds
      @vlmdrounds หลายเดือนก่อน

      @user-jy8nn6uv9n Just off the top of my head, the flavanols can have cardio-protective effects and antioxidant properties. The phenols are also antioxidants. They contain some healthy minerals (alas, along with the unhealthy ones like lead and cadmium). The dose, however, is important as it has to be fairly significant to have a measurable effect, maybe 1/4 to 1/2 a bar a day. I personally don't really think it's worth the potential dose of lead and cadmium on a daily basis. .

    • @JohnnyBoy-c4b
      @JohnnyBoy-c4b หลายเดือนก่อน

      @@vlmdrounds Thank you!

  • @jkbc
    @jkbc หลายเดือนก่อน

    the choices are die by sugar die by eating chocolate or die by doing nothing

  • @howardcohen6817
    @howardcohen6817 หลายเดือนก่อน

    very well done, Loh. I seem to recall that chocolate from Peru (West Africa) is more contaminated as from the more central countries (like you said - has to do with the kind of earth in which the plants grow. Coffee? Thanks.

    • @vlmdrounds
      @vlmdrounds หลายเดือนก่อน

      Thank you! Yes, well, it's not my favorite drink but coffee is protective against liver cancer, so I drink it medicinally!

    • @cathybrown4102
      @cathybrown4102 หลายเดือนก่อน

      Peru is in South America. Ghana which is in Africa has better cocoa with less heavy metals

  • @pinkpanther7030
    @pinkpanther7030 หลายเดือนก่อน

    To eat daily just a bit out of 100gr. bar of dark chocolate can it be safe? Or opting for a milk chocolate instead, is it safer I wonder.

    • @vlmdrounds
      @vlmdrounds หลายเดือนก่อน

      The milk chocolate has less contamination but then there's more sugar, so that's the trade off. If you do opt for small amounts of dark chocolate, then do it after a meal and not on an empty stomach.

    • @pinkpanther7030
      @pinkpanther7030 หลายเดือนก่อน

      @@vlmdrounds 🙂 thanks

  • @KrystalW-n2r
    @KrystalW-n2r 2 หลายเดือนก่อน

    Thanks for the info, watching my hives inflammation fade day after day until they completely vanished was such a relief, I went with what I pointed out and within the first 10 days or so the urticaria was barely visible! I just go'ogled the latest by Shane Zormander and after 20 days my skin has never been healthier!

  • @Phosphoenoylpyruvate
    @Phosphoenoylpyruvate 2 หลายเดือนก่อน

    Nobody also talks about the p450 or the catalase pathway. The thing is the catalase, p450 and alcohol DH pathway are all part of the oxidative pathway and there is a separate non oxidative pathway

  • @kardste8114
    @kardste8114 2 หลายเดือนก่อน

    Yes please do a Full episode on treatment for cancer cachexia.💜🙏

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      Will do, within next few months

  • @cookfamily4824
    @cookfamily4824 2 หลายเดือนก่อน

    Thank you. Moments on meat diet please

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      Okay, will add to request list!

  • @dry509
    @dry509 2 หลายเดือนก่อน

    So what creates this damaging free radical?

  • @dry509
    @dry509 2 หลายเดือนก่อน

    So how do I reduce inflammation/ lower number of particles with nutrition? What foods can I eat?

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      Sorry, just saw this--have been working intensely and didn't catch this till now, and will also be traveling next 2 weeks but will try to address while on the road...

  • @dry509
    @dry509 2 หลายเดือนก่อน

    So Dr Loh what foods, drinks cause the inflammation in the first place…please advise? Did I miss it?

  • @dry509
    @dry509 2 หลายเดือนก่อน

    So how to fix or prevent this phenomenon?

  • @tootstoyou1
    @tootstoyou1 2 หลายเดือนก่อน

    I think I’m convinced. No more alcohol 😅

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      Good decision. Yes, it's toxic, is a Group 1 carcinogen, deposits iron in your organs including your brains, prevents your body from metabolizing anything else that you have eaten until it has metabolized the alcohol first (because it is so toxic and needs to be removed from the body ASAP) and also is associated with INCREASED cardiovascular risks. I am glad you are safeguarding your health!

  • @angeliclight-h8h
    @angeliclight-h8h 2 หลายเดือนก่อน

    Hi Hershey cocoa powder is there lead cadinum or what ever chemical please let me know thank you .

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      @user-kg5ij5ic6b According to Consumer Reports, Hershey's Naturally Unsweetened 100% Cocoa Powder contained 125% lead and 18% cadmium. Percentages refer to the % above California’s maximum allowable dose level of 0.5 micrograms for lead and 4.1 micrograms for cadmium.

    • @howardcohen6817
      @howardcohen6817 หลายเดือนก่อน

      The numbers are devastating. It's no wonder that Hershey -one of the first and biggest USAmerican companies in Peru do their best to conceal this. Some of the Dutch, bio-Kakao are relatively low in poisons. I enjoy 85% chocolate and add to it what I like. I grew up being addicted to Hershey's kisses.

  • @edwcnj1
    @edwcnj1 2 หลายเดือนก่อน

    I've read that the brain likes routines, as such, you don't necessarily want to alter your sleep hours in the attempt to make up the lack of sleep.

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      That is correct. Once you alter your sleep times you affect your circadian rhythm and give yourself jetlag. You can find the full episode here: th-cam.com/video/qdDyR8CAs40/w-d-xo.htmlsi=6cd21nueAGvz49PC

  • @Bee-833
    @Bee-833 2 หลายเดือนก่อน

    You are my hero. You saved my life through Transform.

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      Thank you! I am so happy to have been part of your health journey.

  • @debarghyasaha6801
    @debarghyasaha6801 2 หลายเดือนก่อน

    Really educative video. I appreciate your effort to teach us about the various harmful effects of lead and cadmium. Thank you❤❤

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      So glad it was helpful!

  • @betzib8021
    @betzib8021 3 หลายเดือนก่อน

    Could you just cut to the chase and tell us how to buy it without heavy metals since I don't want either lead or sugar.

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      Hi, sorry, I know it's long and although I try to make it less technical, the focus audience is science/healthcare professionals so had to go into more detail. I have been meaning to do a more general consumer friendly video but it's been challenging managing this channel and full-time work. Anyway, re: how to buy it: basically it is really hard to find uncontaminated cocoa. For this reason I focused on how to consume it to lessen toxic absorption. Sadly, the higher the sugar content, the less toxic contamination and vice versa. I can only offer ways to consume that would decrease absorption. Perhaps one solution would be to find chocolate that has been sweetened with non-sugar sweeteners--just a thought.

    • @jeanpaultongeren125
      @jeanpaultongeren125 2 หลายเดือนก่อน

      @@vlmdrounds that means I cant eat chocolate no more. What a bummer

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      @@jeanpaultongeren125 Maybe in small amounts and never on an empty stomach...try a brand with less contamination such as the Ghirardelli brand...

    • @callmeishmael3031
      @callmeishmael3031 2 หลายเดือนก่อน

      Ghirardelli 86% is the better of the bunch.

    • @jeanpaultongeren125
      @jeanpaultongeren125 2 หลายเดือนก่อน

      @@callmeishmael3031 cant buy that one here. I still have 3 bars of LIndt 100% n my closet

  • @Seanonyoutube
    @Seanonyoutube 3 หลายเดือนก่อน

    “When you’re in a broken system, that system only knows to recreate versions of itself and will not allow you to create something new” Profound and so true.

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      The trouble is that most people confuse change with innovation. They then go about "innovating" when what they are really doing is creating "change".

    • @Seanonyoutube
      @Seanonyoutube 3 หลายเดือนก่อน

      @@vlmdrounds yeah, it’s often hard to tell at the time if a change will really end up being an improvement.

  • @Seanonyoutube
    @Seanonyoutube 3 หลายเดือนก่อน

    1:01:18 so you wouldn’t recommend cannibalism?

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      No! However, I did spend time researching the topic as a rabbit hole I went down when reading on something else...

    • @Seanonyoutube
      @Seanonyoutube 3 หลายเดือนก่อน

      @@vlmdrounds ah, darn it! 😛

  • @Seanonyoutube
    @Seanonyoutube 3 หลายเดือนก่อน

    Q: what is the optimal eating pattern for a late night shift worker (who works till 1am and sleeps around 3am)?

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      You'd need to shift your clock. I'd say to eat a light meal no later than 1 am (say a protein shake) and then make sure you use an eye mask and drapes to keep your surroundings light-proof. Sleep your 8 hours then upon waking, expose yourself to light. Your breakfast will be later in the day as will all your meals but just follow the 'clock' you have established for yourself and keep it consistent.

    • @Seanonyoutube
      @Seanonyoutube 3 หลายเดือนก่อน

      @@vlmdrounds interesting that you recommend protein two hours before bed… is that enough time to fully digest it? I know protein is quite thermogenic… although I guess whey is quicker digesting…thanks!

  • @Seanonyoutube
    @Seanonyoutube 3 หลายเดือนก่อน

    Damn 13:07 happens to me often when I dream i’m running away from someone chasing me or something and I wake up but my body is locked! Lol now I know why

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      I've had that happen to me and it's pretty scary!

    • @Seanonyoutube
      @Seanonyoutube 3 หลายเดือนก่อน

      @@vlmdrounds often I’ll also get it when I dream that there is a scary person in my bedroom by my bedside! I wake up in panic but I clearly recall the “waiting period” before I can actually check the room to make sure its clear

  • @Seanonyoutube
    @Seanonyoutube 3 หลายเดือนก่อน

    Ok…how do we get more REM?

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      Basically you have to sleep 7-8 hours. Your REM sleep is at the end of the night and if you cut shrt your sleep you will not get to most of your REM phases. Check our my full episode on sleep for details: th-cam.com/video/qdDyR8CAs40/w-d-xo.htmlsi=02OlOOYJUPLHK6tA Also alcohol and sleeping pills interfere with REM sleep so best to avoid them.

  • @ervinjackson3261
    @ervinjackson3261 3 หลายเดือนก่อน

    I’m a scholar I’ve been studying the stuff for years it’s true

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      Thank you for watching. I wish we had better quality control on our food supply!

    • @betzib8021
      @betzib8021 3 หลายเดือนก่อน

      @@ervinjackson3261 so where do you get chocolate?

    • @vlmdrounds
      @vlmdrounds 2 หลายเดือนก่อน

      @@betzib8021 Personally, I am not a chocolate fan (sorry). More a vanilla fan. However, I do mention towards the end how to decrease absorption of those chemicals when you do eat chocolate.

  • @ervinjackson3261
    @ervinjackson3261 3 หลายเดือนก่อน

    I hate to say it, but everything is poison. It ain’t gonna kill you right away but when you get cancer one day, you don’t know where it came from that’s the sad news. Even the air and water is poison fluoride the air got aluminum in it phosphate and even the medicine so you think that’s a accident lol your phosphate is in the lakes and screams so everything is poison what about that?

  • @Kecharitomene1
    @Kecharitomene1 3 หลายเดือนก่อน

    “Listen, snake venom is natural!” 😂😂 I’m going to use that line

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      Glad you like it! 😁

  • @Dai-Verse-IT
    @Dai-Verse-IT 3 หลายเดือนก่อน

    👍

  • @josevalverde2263
    @josevalverde2263 3 หลายเดือนก่อน

    What can humans eat?

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      I know, it's sad, isn't it? Everything is contaminated these days!

    • @AlexLacorum-hf9ie
      @AlexLacorum-hf9ie หลายเดือนก่อน

      Eat organic if possible and for those foods that had toxic metals and substances if possible refrain from eating or minimize consuming and have a regular exercises to prevent toxic to accumulates since sweating carries toxic outside the body . In organic store they sale organic cosmetic, tooth paste, soap, laundry soap, shampoo, conditioner etc. So replace those non organic to organic products we use personally. And also use stainless coockwares since others coockwares when heated in high temperature emates poisonous chemicals that goes to the food your cooking. And also be aware of the low radiation on microwaves, tv, laptop and cellphones.

  • @samimeat8239
    @samimeat8239 3 หลายเดือนก่อน

    Is there thermochemistry videos my exams is in25/6

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      I don't have any on thermochemistry, I'm afraid. What is it about thermochemistry that you want clarified?

    • @samimeat8239
      @samimeat8239 3 หลายเดือนก่อน

      @@vlmdrounds I have my exams and I feel frustrated some how I didn't get a good mark on the partial and this us the final ,we are taking thermochemistry hess law and the others law to calculate enthalpy change kichrofs law bond formation or dissociation and born haber cycle it is called maybe and chemical kinetics entropy gibs free energy chemical equilibrium kc and kp

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      @@samimeat8239 I won't have time at such short notice to make videos on those topics, but you might find this person's videos helpful: th-cam.com/video/XhtE_XYbBUI/w-d-xo.htmlsi=EOlJlJixZdZ8-Pi8 Good luck!

    • @samimeat8239
      @samimeat8239 3 หลายเดือนก่อน

      @@vlmdrounds thank you amigo

  • @flanker909
    @flanker909 3 หลายเดือนก่อน

    Sweet lady and interesting information. I love dark chocolate, it's one of my favorite snacks but with this in mind I try now to lower my consumption and go for 70% cocoa instead of 85/90%.

    • @vlmdrounds
      @vlmdrounds 3 หลายเดือนก่อน

      Thank you. And don't eat your chocolate on an empty stomach!

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    It is sad to think that medical text books don't do a good job of updating their content in light of new research. My first exposure to that idea is that the vascular endothelium glycocalyx (yes, that YT search is what led me to your channel) is not shown in the graphics, or pictorials. Why that is isn't hard to understand because when dissection is done, the glycocalyx is gone, when slides are prepped, the glycocalyx is destroyed, it is only recently that the glycocalyx has been visualized with cameras in vivo. And there are few doctors that are on a path of continuous education, even if the text books were current. So we want to tread lightly, and don't buy into, or consume someone's theory without understanding the foundation concepts. Sometimes, when you pull back the curtain a little and look - there is no foundation. Sometimes the foundation has good information, but gets stuck with goofy names because our understanding is confined by the limitations of technology. _We see as through a glass, darkly_ I am beginning to consider the life of LipoProteins as a continuum in a process, rather than existing in our pre-defined buckets of classification. Keep learning, and thanks for sharing!

  • @conscience-commenter
    @conscience-commenter 4 หลายเดือนก่อน

    Solutions 34:01: chelation with citric acid ,calcium EDTA , pyridoxamine and benfotiamine , Make sure you are not deficient in minerals and vitamins. Iron, zinc, calcium deficiency increase heavy metal absorption.. Children under 12 and pregnant women must abstain or eat small amounts with a meal to decrease heavy metal absorption .Please read Consumer Reports article : Lead and Cadmium could be in your dark chocolate. In it they show various bars with metal percentages found. Least amounts found in : Mast , Taza 70% cacao ,Ghirardelli 86% ,72% cacao and Valrhona 85% cacao .

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    First. (commented 4 Al Gore's rhythm ;)

    • @vlmdrounds
      @vlmdrounds 4 หลายเดือนก่อน

      😁😆

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    Is there really much of a difference in the cause of atherosclerosis vs. aneurisms?

    • @vlmdrounds
      @vlmdrounds 4 หลายเดือนก่อน

      An aneurysm is a defect in the blood vessel wall resulting in a bulging or ballooning out of the wall. It can be due to tissue defects and, when they reach a certain size, are at risk of rupture and an internal bleed. The pathogenesis is different from atherosclerosis.

    • @jamesalles139
      @jamesalles139 4 หลายเดือนก่อน

      @@vlmdrounds Thank you for your response! And thank you for the definition, as well. It is clear that the observed effect is quite different (clotting vs. bleeding out). The physiology (or anatomy?) is also different. It would seem to me that the pressure gradient is a significant factor in an aneurysm rupture. It appears that the pathogenesis of an aneurysm is less well understood than that of atherosclerosis - except in the case of physical defect or injury. The pathogenesis of atherosclerosis is not as well understood as some people assume. Inflammation does appear to be a risk factor in both. My apologies for pushing back, I do realize that you are not a <vascular surgeon>, and my original question was in case you had taken special interest as you bring unique insight from your 'deep dives', which we all appreciate. So my brief Googling of a couple of generally reputable websites and browsing a couple of research papers brings these results: *The University of Michigan Samuel & Jean Frankel Cardiovascular Center* _Atherosclerosis is a major cause of abdominal aortic aneurysm and is the most common kind of arteriosclerosis, or hardening of the arteries._ *Mayo Clinic* Aneurysms. _Atherosclerosis can also cause aneurysms, a serious complication that can occur anywhere in the body. Most people with aneurysms have no symptoms. Pain and throbbing in the area of an aneurysm may occur and is a medical emergency. If an aneurysm bursts, it can cause life-threatening bleeding inside the body._ *Are Aortic Aneurysms Caused by Atherosclerosis?* Conclsions. _From the perspective of prevention, it appears that the risk factors for aortic atherosclerosis and probably atherosclerosis itself are necessary elements in the causal pathway for the great majority of aortic aneurysms in this cohort._ *Atherosclerosis and abdominal aortic aneurysm: Cause, response or common risk factors?* _The authors suggest that their findings fit better with atherosclerosis and AAA developing in parallel rather than atherosclerosis directly leading to AAA. _*_[...]_*_ the findings from the current study are not able to convincingly refute a role for atherosclerosis in AAA._ So, the science isn't settled. As for me, I have confidence that using my keto ==> carnivore leaning diet to minmimize blood sugar spikes and protect my glycocalyx; limiting ultra-processed 'foods' & ferreting out industrial processed seed oils from consumption (including 'health' supplements in soft-gels); and finally increasing exercise activity will help arrest the progression of both of these conditions. thanks again!

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    My working theory is that atherosclerosis is a one-two punch, or like a binary explosive (but lots of little firecrackers). There are many compounds that can wash out the glycocalyx. The glycocalyx acts as our shields, and It takes many hours for it to be restored. Focusing on high blood glucose as a wash-out mechanism, in the Standard American Diet (SAD) we get glucose spikes from multiple meals a day (including snacks) sugary drinks (including 100% fruit juice). The glycocalyx just doesn't have a chance to properly rebuild - sleeping hours isn't enough time. That all cascades much worse with insulin resistance / diabetes. Glucose itself can glycate any cell, but is it enough to cause an inflammatory reaction? Sugar by itself has been declared to be 'safe' in the 'science'. With the glycocalyx washed out, Nitrous Oxide is not released, so blood pressure may increase. Hypertension is now seen as part of the greater metabolic disorder. Oxidized products are inflammatory, and damaged LDL is a problem - identified as small, dense LDL. As you say, damaged enough as to be not recognized by the usual receptors to be removed from circulation (so they build up) , and to be identified as a foreign body by our immune system. But the vascular walls are well protected by the glycocalyx from most of the many toxins we are exposed to except for specific high-flow sites, like branches and sharp turns. Damage is minimal. Industrially processed seed oils are highly oxidative, but are Generally Recognized As Safe (GRAS). But in the continuous presence of all of the glucose in our diet, our shields are down, and the sdLDL and other oxidized products cause injury to and overwhelm the epithelium, and make their way into the vessel wall, where the auto-immune response ensues. sorry for mangling the terminology. I see the problem as the *combination* of sugar and oxidized seed oils in our ultra-processed food diet. Separately, not so bad. Our body can handle a little sugar from fruit, milk, or honey. The seed oils, it just tries to sequester that stuff. And something I haven't seen talked about - why would there be a mechanism to wash out our vascular endothelial glycocalyx on a temporary basis? That would be the flight-or-fight mechanism, in my estimation. Cortisol + Adrenaline dump glucose, washing out the glycocalyx keeping the blood vessels restricted and increasing blood pressure with the increased blood flow to push energy to every nook and cranny of the capillaries. This runs the risk of damage for a time, during an emergency. _Desperate Times Call for Desperate Measures._ It doesn't seem like running marathons continuously are good for longevity. As for me, the best strategy to eliminate sdLDL and other factors is whole blood donation. Maybe there was something to the practice of blood-letting. Today it is a win-win situation, good for society as well.

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    Are you seeing the evidence from the Lean Mass Hyper-Responder (LMHR) studies? Dave Feldman, Nick Norwitz PHD, Dr. William Cromwell. I look at a LDL-cholesterol/apolipoprotein B ratio of 1.52 as good (at this time)

    • @vlmdrounds
      @vlmdrounds 4 หลายเดือนก่อน

      I'm afraid I haven't been following the studies you mentioned. Maybe when I have a bigger team one day. Right now it's a bit of a juggling act trying to do everything on my own!

    • @jamesalles139
      @jamesalles139 4 หลายเดือนก่อน

      @@vlmdrounds Understood. I don't have the background that you do, so I have the luxury of glossing over some of the details. With the US healthcare establishment failing me, I am just attempting to navigate the better signals amongst the noise. It is refreshing to learn that the science isn't settled - but that we are fearfully and wonderfully made! Each of the scientists I mentioned have YT channels - a suggestion for critiques in future videos?

    • @vlmdrounds
      @vlmdrounds 4 หลายเดือนก่อน

      @@jamesalles139 Thank you. I am sorry that you have had to be under the current sick care system. My dream is that there be a real, science-based alternative for everyone one day!

    • @jamesalles139
      @jamesalles139 4 หลายเดือนก่อน

      @@vlmdrounds Oh my and LoL I felt bad saying that you weren't a <surgeon> in another post, and figured I really ought to do some research to see if I knew what I was talking about. Dr. Loh, you don't go overboard 'tooting your own horn' on this YT platform. And guess who I stumbled on. A patient. On Metabolic Multiplier. _Love a conversation that heals: Dr. Vyvyane Loh_ BY NICHOLAS NORWITZ · PUBLISHED OCTOBER 8, 2020 · UPDATED DECEMBER 27, 2022 I am beside myself, having pretty much stepped in it. speechless, I am going to get my dinner. It is nice when the world gets smaller.

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    Well then, to borrow from others: Our shields (glycocalyx) are down long enough for inflammation to take hold (catch fire) in the endothelial layer / vascular wall. The immune system dispatches fire trucks (lipoproteins) to deliver the firefighters. Years ago, with rudimentary research tools, we found the outlines of turnout gear (cholesterol? maybe? phytosterols?) of firefighters at the scene of the conflagration, and deemed the fire trucks guilty of arson, and started impounding them (with statins).

  • @jamesalles139
    @jamesalles139 4 หลายเดือนก่อน

    And yet, we end up affecting cholesterol synthesis in the brain. sigh. From the medical establishments perspective I am taking a crap shoot anyway. I have minimized carbohydrate intake and removed industrially processed seed oils from my diet. Having a CAC score of 543, I am starting 1mg per day of pitavastatin for the the pleotropic effects, rather than lowering LDL. next therapy: more exercise, less YT video watching. "Eat more, move more"

    • @vlmdrounds
      @vlmdrounds 4 หลายเดือนก่อน

      @jamesalles139 It's wonderful that you are prioritizing your health through diet and are now working on exercise. If you are worried about brain effects of statins, have a discussion with your care provider on lipophilic vs. hydrophilic statins (pitavastatin is lipophilic)

  • @conradnorton6799
    @conradnorton6799 4 หลายเดือนก่อน

    Thank you so much Vyvyane! This is brilliant. I wasn't aware you could be have deficiency and excess at the same time across different organs.

    • @vlmdrounds
      @vlmdrounds 4 หลายเดือนก่อน

      Yes, I don't think many people are aware of that and that iblood iron studies may not reflect what is going on in the body at all. Also, how iron impacts cholesterol metabolism in endothelial cells--very intriguing!