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OncBrothers: Practice-Changing Cancer Discussions
United States
เข้าร่วมเมื่อ 14 มิ.ย. 2022
On a mission to disseminate information to the community and bridge the gap between academia and community oncology in this rapidly changing field of hematology & oncology. Drs. Rahul & Rohit Gosain interview world-renowned hematologists/oncologists to present the practice-changing data in a small bite-sized format where one could immediately apply that information in their daily practice to provide the best cancer care to their patients close to home.
How to Treat Triple Negative Breast Cancer - Discussion with Dr. Virginia Kaklamani
Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Virginia Kaklamani from the UTHealth San Antonio MD Anderson Cancer Center to discuss the latest advances in the treatment of triple negative breast cancer (TNBC) as we kick off 2025.
• The treatment paradigms for early-stage TNBC, including the role Sacituzumab and radiation therapy.
• Insights from the SABCS 2024 conference, focusing on the keynote 522 regimen and its implications for neoadjuvant treatment.
• The management of locally advanced and metastatic TNBC, including the use of immunotherapy and the importance of PD-L1 testing.
• Strategies for managing toxicities associated with treatments like sacituzumab and T-DXd.
Whether you're a healthcare professional or someone interested in the latest in oncology, this episode provides valuable insights into the evolving landscape of breast cancer treatment. Don't forget to like, subscribe, and hit the notification bell for more updates from the Oncology Brothers!
Key Takeaways:
• Current standard of care for locally advanced TNBC.
• The significance of chemotherapy and immunotherapy in treatment plans.
• Managing toxicities in metastatic disease.
Stay tuned for more discussions on treatment algorithms, FDA approvals, and clinical pearls in oncology!
Apple Podcast: podcasts.apple.com/us/podcast/how-to-treat-triple-negative-breast-cancer-discussion/id1653340966?i=1000690836995
Spotify: creators.spotify.com/pod/show/oncology-brothers/episodes/How-to-Treat-Triple-Negative-Breast-Cancer---Discussion-with-Dr--Virginia-Kaklamani-e2ulsj5/a-abp90lg
Follow us on social media:
• X/Twitter: oncbrothers
• Instagram: oncbrothers
• The treatment paradigms for early-stage TNBC, including the role Sacituzumab and radiation therapy.
• Insights from the SABCS 2024 conference, focusing on the keynote 522 regimen and its implications for neoadjuvant treatment.
• The management of locally advanced and metastatic TNBC, including the use of immunotherapy and the importance of PD-L1 testing.
• Strategies for managing toxicities associated with treatments like sacituzumab and T-DXd.
Whether you're a healthcare professional or someone interested in the latest in oncology, this episode provides valuable insights into the evolving landscape of breast cancer treatment. Don't forget to like, subscribe, and hit the notification bell for more updates from the Oncology Brothers!
Key Takeaways:
• Current standard of care for locally advanced TNBC.
• The significance of chemotherapy and immunotherapy in treatment plans.
• Managing toxicities in metastatic disease.
Stay tuned for more discussions on treatment algorithms, FDA approvals, and clinical pearls in oncology!
Apple Podcast: podcasts.apple.com/us/podcast/how-to-treat-triple-negative-breast-cancer-discussion/id1653340966?i=1000690836995
Spotify: creators.spotify.com/pod/show/oncology-brothers/episodes/How-to-Treat-Triple-Negative-Breast-Cancer---Discussion-with-Dr--Virginia-Kaklamani-e2ulsj5/a-abp90lg
Follow us on social media:
• X/Twitter: oncbrothers
• Instagram: oncbrothers
มุมมอง: 927
วีดีโอ
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Finally whats the result of this discussion in T1c patients !? Do you recommend neo-adjuvant in 2025 as a standard of care or still its contraversial again !???
Add new gastric and esophag updates too
Great , thank you for keeping us updated , specially in our countries where to be updated is a little bit difficult
Great discussion
Great discussion as always
Which immunotherapies possibly break blood brain barrier?
Unfortunately these formulas are very expensive in our country. And “COST” is very important for our patients.
If I have an m strike I'm seven and my kappa free light Chainz is 21.9 and my lamboda light Chainz is 49.8
Is Bevacizumab absolutely contraindicated in patients who have a coronary stent at any point in their life or only recent angioplasty?
Agree 100%
I was diagnosed with breast cancer two years ago, and after undergoing treatments, I still felt weak and unsure about my recovery. That’s when I discovered Harvey’s Herbal Healing Remedies. I started using their herbal cancer support supplements, and I felt a significant improvement in my energy levels and overall well-being. Today, my doctor says I’m cancer-free, and I believe these remedies played a huge role in my healing journey. Thank you for helping me restore my health naturally!
“I was diagnosed with breast cancer two years ago, and after undergoing treatments, I still felt weak and unsure about my recovery. That’s when I discovered Harvey’s Herbal Healing Remedies. I started using their herbal cancer support supplements, and I felt a significant improvement in my energy levels and overall well-being. Today, my doctor says I’m cancer-free, and I believe these remedies played a huge role in my healing journey. Thank you for helping me restore my health naturally!
“I was diagnosed with breast cancer two years ago, and after undergoing treatments, I still felt weak and unsure about my recovery. That’s when I discovered Harvey’s Herbal Healing Remedies. I started using their herbal cancer support supplements, and I felt a significant improvement in my energy levels and overall well-being. Today, my doctor says I’m cancer-free, and I believe these remedies played a huge role in my healing journey. Thank you for helping me restore my health naturally!
Very exciting Thanks so much ❤
I'm just starting my journey. Diagnosed 27th December 2024 age 71. Waiting to see a Hematologist on 20th January. Great video.
This topic is close to my heart. I've been on a healing journey after a breast cancer diagnosis, and natural remedies played a role in my recovery. If anyone is curious about my experience or wants to talk, feel free to reach out!
“I was diagnosed with breast cancer two years ago, and after undergoing treatments, I still felt weak and unsure about my recovery. That’s when I discovered Harvey’s Herbal Healing Remedies. I started using their herbal cancer support supplements, and I felt a significant improvement in my energy levels and overall well-being. Today, my doctor says I’m cancer-free, and I believe these remedies played a huge role in my healing journey. Thank you for helping me restore my health naturally!
I have an MGUS diagnosis and have had a bone marrow biopsy. This is the best discussion on the topic that I have seen so far. I have been seeing many of the issues that have been raised here; arbitrary diagnosis based on arbitrary levels. I have yet to see anyone looking at derivatives in test results which would seem to ring the alarm bells. Also waiting until you are really sick to start treatment doesn’t work for any other cancer so why is it considered best practice here?
great work
I was diagnosed with MGUS when investigating GBS. I still have peripheral neuropathy, back pain, fatigue and little-to-no reflexes 3 years on and wonder if MGUS paraprotein is a factor in my symptoms? I got many blood plasma infusions... also wondering if there were spike proteins in the plasma too that exacerbated symptoms?
Wackel Dackel
Im also cml patient..can i live a long life or not??
yes!!! I was told I'll die with this, not from it.
I have Her2+ 3mm removed from left breast no nodes effected have had chemo and am on trzumabab and on anastrozone therapy surgery 6 months ago now they suggested radiation originally no radiation was mentioned they said 98 % clear should I benefit from radiation now
Awesome
💜
Good
This is MY oncologist and I love him dearly. He is the best that ever done it. He provides the most awesome care to me that I could have ever imagined. he is a great listener and he goes above and beyond his duties to ensure that I am receiving the highest quality of care emotionally as well as medically and physically ..I don’t know what my cancer Journey would have been like without him… I totally trust his judgment, suggestions, and professional knowledge and expertise as well as his amazing medical team that works along closely with him. If you’re like me battling lung cancer, this is the doctor you would want to have… keep up the good work DR.REUSS,..keep saving lives and giving hope to the hopeless, you are amazing and gifted by God in my book🙏🏾🙏🏾
Have any of you doctors looked into Dr. Thomas Seyfrieds work on cancer being caused by a meatabolic disorder?
today i got tested and became an oncologist, and this is exactly what i wished i had seen 24 hrs earilier. all other aspects and protocols you talked about served me greatly. keep up such blessed work.
you guys just keep making it better and better! please bring back the images, treating schema and screenshots of the main trials
Thank you for this very informative talk
excellent summation. thanks.
Nice topic
😊 Breast cancer very interesting Field 😊😊.
Thanks for tips
Another awesome update! Are there any plans to offer CMEs for watching the discussions and probably taking a test afterwards?
Nice
Excellent
She sounded Irish, was she? Is she in America or Ireland?
Perfect👏🏻👏🏻
hi thanks for the clips please add Sarcoma , Metastatic breast cancer and latest of ALL to your upcoming discussions!
Holistic approach please, not cut and burn. Big pharma always? Or perhaps not.
Really thanks for this topic ... hope to see more of net, nec and ALL , rectum , ... thanks
Thank you for this conversation. It will be great if we can discuss topics like cancer related fatigue and pain in general. This helps community oncologists to manage symptoms especially when we don't have access to palliative care service. Thank you
My husband will be getting tarlatamab in about 1 1/2 weeks. Hopefully he will be able to get histotripsy on his liver as well.
hello, where do you live? I wonder how you got the medicine? My 39-year-old brother has small cell lung cancer. liver met. No medicine worked. We are in Turkey and this medicine is not available here yet. We cannot get it ourselves. Does your husband also have small cell lung cancer? How did you manage the process?
@GülşahKandemir-h1l We are in the USA. My husband will be the second person to get tarlatamab in our area. If you are referring to the histotripsy for the liver, it is not a medicine. It is a procedure using ultrasound. We are not sure yet where he would go for that. I pray the best for your brother.
@@windybassham3130 I wish the best for everyone who is looking for a cure. Lung cancer has metastasized to the liver. I hope treatment starts in Turkey as soon as possible. I hope your husband gets his best healthy life.
As always this is pure Gold!
Very helpful. Thank you.
I am a medical oncologist from Pakistan. I will say ur vidoes are amazing, watching them regularly. Learnt alot especially from the algorithm. Unfortunately Tx are for well developed countries. I would request you to involve Low income countries and ask them real world treatments they give and find the gaps
I am a medical oncologist from Pakistan. I will say ur vidoes are amazing, watching them regularly. Learnt alot especially from the algorithm. Unfortunately Tx are for well developed countries. I would request you to involve Low income countries and ask them real world treatments they give and find the gaps
Great work sir
Standard of care? How sad . Treating any and all cancer types using standard of care is like a cop showing up after the shooting is over … Treating radical cell division (cancer ) by trying to kill the cancer with radiation etc. instead of just cutting off what feeds the cancer and just starving it. Cancer feeds on only two foods Glutamine and glucose ( sugar ) thru fermentation …cut the carbs and feed your body on ketones Cancer can’t feed on ketones