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OncBrothers: Practice-Changing Cancer Discussions
United States
เข้าร่วมเมื่อ 14 มิ.ย. 2022
On a mission to disseminate information to the community and bridge the gap between academia and community oncology in this rapidly changing field of hematology & oncology. Drs. Rahul & Rohit Gosain interview world-renowned hematologists/oncologists to present the practice-changing data in a small bite-sized format where one could immediately apply that information in their daily practice to provide the best cancer care to their patients close to home.
CAR-T Toxicity Check: From Approval to Practice, Managing Side Effects of CAR-T Therapy
Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain dive deep into the rapidly evolving world of CAR T cell therapy, a groundbreaking treatment for various hematologic malignancies. Joined by experts Dr. Surbhi Sidana from Stanford University and Dr. Jason Westin from MD Anderson Cancer Center, we explore the mechanism of action of CAR T cells, their side effects, and management strategies.
Episode Highlights:
• Understanding CAR T cell therapy and its application in hematologic malignancies and solid tumors.
• Mechanism of action: How CAR T cells are engineered to target cancer cells.
• Acute side effects: Cytokine release syndrome (CRS) and neurotoxicity, including clinical pearls for management.
• Chronic side effects: Monitoring for infections, cytopenias, and the risk of secondary malignancies.
• The importance of bridging therapy and managing tumor burden before CAR T treatment.
• Insights for community oncologists on patient management and communication with CAR T centers.
Join us for an informative discussion that emphasizes the importance of recognizing and managing the unique side effects of CAR T therapy to ensure the best outcomes for patients. Don't forget to check out our other episodes for more insights into recent advances in hematology and oncology!
Subscribe for more discussions on FDA approvals, treatment algorithms, and conference highlights. We are the Oncology Brothers!
Website: www.oncbrothers.com/
X/Twitter: oncbrothers
Contact us at info@oncbrothers.com
Episode Highlights:
• Understanding CAR T cell therapy and its application in hematologic malignancies and solid tumors.
• Mechanism of action: How CAR T cells are engineered to target cancer cells.
• Acute side effects: Cytokine release syndrome (CRS) and neurotoxicity, including clinical pearls for management.
• Chronic side effects: Monitoring for infections, cytopenias, and the risk of secondary malignancies.
• The importance of bridging therapy and managing tumor burden before CAR T treatment.
• Insights for community oncologists on patient management and communication with CAR T centers.
Join us for an informative discussion that emphasizes the importance of recognizing and managing the unique side effects of CAR T therapy to ensure the best outcomes for patients. Don't forget to check out our other episodes for more insights into recent advances in hematology and oncology!
Subscribe for more discussions on FDA approvals, treatment algorithms, and conference highlights. We are the Oncology Brothers!
Website: www.oncbrothers.com/
X/Twitter: oncbrothers
Contact us at info@oncbrothers.com
มุมมอง: 96
วีดีโอ
Leukemia ASH 2024 Highlights - Menin Inhibitors, CPX 351 vs 7+3, Venetoclax Based Regimens
มุมมอง 1.5K7 ชั่วโมงที่ผ่านมา
Welcome back to the Oncology Brothers podcast! In this episode, we dive into the highlights from ASH 2024, focusing on key studies in leukemia. Join hosts Drs. Rahul and Rohit Gosain as they discuss groundbreaking research with Dr. Uma Borate from The Ohio State University. Episode Highlights: • KOMET 007 Study: An in-depth look at the Phase 1 study on the Menin inhibitor Ziftomenib, explorin...
2nd line treatment in advanced HCC and when to switch
มุมมอง 2.6K21 ชั่วโมงที่ผ่านมา
In the second episode of a 4-part podcast series on HCC, the Oncology Brothers, Drs Rahul and Rohit Gosain, host a podcast discussion between Dr Lorenza Rimassa and Prof. Arndt Vogel on 2nd line treatment selection in advanced HCC and when to switch. The discussion covers a range of topics, including 2nd line options for advanced HCC after progression on 1st line TKIs and IO-based therapies, as...
From Approval to Practice: Managing Side Effects of Antibody Drug Conjugates (ADC) in Cancer
มุมมอง 2.7K14 วันที่ผ่านมา
Welcome to another episode of the Oncology Brothers! In this episode, hosts Drs. Rahul and Rohit Gosain dive into the complexities of managing side effects associated with antibody drug conjugates (ADCs). Joined by expert guests Dr. Tian Zhang, a GU medical oncologist from UT Southwestern, and Dr. Erika Hamilton from Sarah Cannon Research Institute, the discussion focuses on three key ADCs: Enf...
The use of Immunotherapy in unresectable Hepatocellular Carcinoma (HCC)
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Experts provide an overview of current systemic treatment options for 1st line uHCC, discussing the role of IO and IO-based combinations, along with emerging therapies and the latest clinical data. Topics also include: • Efficacy and safety of IO and IO combinations in HCC • How to select between the two 1st-line IO-based treatment options based on clinical factors • Future treatment in unresec...
INAVO120 - FDA Approval of Inavolisib in Endocrine-Resistant, PIK3CA-mut, HR+ Advanced Breast Cancer
มุมมอง 2.5K21 วันที่ผ่านมา
Welcome to another episode of the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain dive deep into the recent FDA approval of Inavolisib for metastatic hormone receptor-positive breast cancer, based on the groundbreaking INAVO120 study. Join us as we chat with Dr. Komal Jhaveri, a medical oncologist and senior author of the study from Memorial Sloan Kettering Cancer ...
How to Approach and Treat Pancreatic Cancer
มุมมอง 2.8Kหลายเดือนก่อน
Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rohit and Rahul Gosain are joined by Dr. Eileen O'Reilly, a leading medical oncologist and section head of hepatobiliary and pancreatic cancer at Memorial Sloan Kettering Cancer Center. Together, they delve into the complex treatment landscape of pancreatic cancer. Episode Highlights: • The initial workup for newly diagnose...
Understanding the Impact of Nutrition & Exercise on Cancer Outcomes
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In this episode of the Oncology Brothers podcast, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Neil Iyengar, a medical oncologist from Memorial Sloan Kettering Cancer Center, to discuss the critical role of nutrition and exercise in cancer care and recurrence prevention. They tackle common questions from cancer survivors about lifestyle modifications that can help reduce the risk of canc...
How to Diagnose, Treat, and Follow Neuroendocrine Tumors (NETs)
มุมมอง 3.2Kหลายเดือนก่อน
In this episode of the Oncology Brothers podcast, hosts Drs. Rohit and Rahul Gosain welcome Dr. Pamela Kunz, a world-renowned medical oncologist from the Yale Cancer Center, to discuss the complex landscape of neuroendocrine tumors (NETs). Join us as we explore: • The classification of neuroendocrine tumors based on grade, histological features, and the significance of KI-67. • The role of ...
Palliative Care Management in Cancer | Onc Brothers
มุมมอง 2.9Kหลายเดือนก่อน
In this episode of the Oncology Brothers podcast, hosts Drs. Rahul and Rohit Gosain are joined by esteemed palliative care experts Dr. Janet Abrahm from Dana-Farber Cancer Institute and Dr. Ishwaria Subbiah from Sarah Cannon Research Institute. Together, they delve into the critical topic of palliative care, exploring its evolution from a focus on end-of-life care to an integral part of cancer ...
How to Approach to Ovarian Cancer from Community Oncology Perspective
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DeLLphi-301 - FDA Approval of Tarlatamab in Patients w/ Prev Treated Small Cell Lung Cancer (SCLC)
มุมมอง 3.1K2 หลายเดือนก่อน
DeLLphi-301 - FDA Approval of Tarlatamab in Patients w/ Prev Treated Small Cell Lung Cancer (SCLC)
AEGEAN Study - FDA Approval of Durvalumab in Resectable Non-Small Cell Lung Cancer
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Lung Cancer ESMO 2024 Highlights: Key Studies Discussed LAURA, MARIPOSA, MARIPOSA-2, ADRIATIC
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AGAVE-201 Study - FDA Approval of Axatilimab for Chronic Graft-versus-Host Disease (cGVHD)
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How to Approach to Acute Myeloid Leukemia (AML) from Community Oncology Perspective
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GI Cancer ESMO 2024 Highlights: Key Studies Discussed LEAP-012, KEYNOTE-811, POD1UM-303, NICHE-2
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GI Cancer ESMO 2024 Highlights: Key Studies Discussed LEAP-012, KEYNOTE-811, POD1UM-303, NICHE-2
GU Cancer ESMO 2024 Highlights: Key Studies Discussed NIAGARA, TiNiVO-2, PEACE-3, CONTACT-02
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GU Cancer ESMO 2024 Highlights: Key Studies Discussed NIAGARA, TiNiVO-2, PEACE-3, CONTACT-02
Breast Cancer ESMO 2024 Highlights: Key Studies Discussed NATALEE, KEYNOTE 522, DESTINY-Breast12
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WCLC 2024 Highlights - Exploring Latest Advances in Lung Cancer Treatment
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How to Treat Chronic Myeloid Leukemia (CML) - Dr. Jorge Cortes
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How to Treat Follicular & Mantle Cell Lymphomas - Discussion with Dr. Pallawi Torka
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How to Treat Follicular & Mantle Cell Lymphomas - Discussion with Dr. Pallawi Torka
How to treat Diffuse Large B-Cell Lymphoma (DLBCL) - Dr. Carla Casulo
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How to treat Cutaneous Melanoma (Skin Cancer) - Dr. Allison Betof Warner
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Role of Cardiology in Cancer Treatment: Cardio-Oncology
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Role of Cardiology in Cancer Treatment: Cardio-Oncology
How to Treat Early Stage Non-Small Cell Lung Cancer
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How to Treat Early Stage Non-Small Cell Lung Cancer
How to Treat Metastatic Non-Small Cell Lung Cancer w/o Targeted Mut in Front-line - Dr. Preeshagul
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How to Treat Non-Small Cell Lung Cancer with Actionable Mutations with Dr. Balazs Halmos
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How to Treat Small Cell Lung Cancer using Treatment Algorithm with Dr. Eric Singhi
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How to Treat Small Cell Lung Cancer using Treatment Algorithm with Dr. Eric Singhi
I have Her2+ 3mm removed from left breast no nodes effected have had chemo and am on trzumabab and on anastrozone therapy surgery 6 months ago now they suggested radiation originally no radiation was mentioned they said 98 % clear should I benefit from radiation now
Awesome
💜
Good
This is MY oncologist and I love him dearly. He is the best that ever done it. He provides the most awesome care to me that I could have ever imagined. he is a great listener and he goes above and beyond his duties to ensure that I am receiving the highest quality of care emotionally as well as medically and physically ..I don’t know what my cancer Journey would have been like without him… I totally trust his judgment, suggestions, and professional knowledge and expertise as well as his amazing medical team that works along closely with him. If you’re like me battling lung cancer, this is the doctor you would want to have… keep up the good work DR.REUSS,..keep saving lives and giving hope to the hopeless, you are amazing and gifted by God in my book🙏🏾🙏🏾
Have any of you doctors looked into Dr. Thomas Seyfrieds work on cancer being caused by a meatabolic disorder?
today i got tested and became an oncologist, and this is exactly what i wished i had seen 24 hrs earilier. all other aspects and protocols you talked about served me greatly. keep up such blessed work.
you guys just keep making it better and better! please bring back the images, treating schema and screenshots of the main trials
Thank you for this very informative talk
excellent summation. thanks.
Nice topic
😊 Breast cancer very interesting Field 😊😊.
Thanks for tips
Another awesome update! Are there any plans to offer CMEs for watching the discussions and probably taking a test afterwards?
Nice
Excellent
She sounded Irish, was she? Is she in America or Ireland?
Perfect👏🏻👏🏻
hi thanks for the clips please add Sarcoma , Metastatic breast cancer and latest of ALL to your upcoming discussions!
Holistic approach please, not cut and burn. Big pharma always? Or perhaps not.
Really thanks for this topic ... hope to see more of net, nec and ALL , rectum , ... thanks
Thank you for this conversation. It will be great if we can discuss topics like cancer related fatigue and pain in general. This helps community oncologists to manage symptoms especially when we don't have access to palliative care service. Thank you
My husband will be getting tarlatamab in about 1 1/2 weeks. Hopefully he will be able to get histotripsy on his liver as well.
hello, where do you live? I wonder how you got the medicine? My 39-year-old brother has small cell lung cancer. liver met. No medicine worked. We are in Turkey and this medicine is not available here yet. We cannot get it ourselves. Does your husband also have small cell lung cancer? How did you manage the process?
@GülşahKandemir-h1l We are in the USA. My husband will be the second person to get tarlatamab in our area. If you are referring to the histotripsy for the liver, it is not a medicine. It is a procedure using ultrasound. We are not sure yet where he would go for that. I pray the best for your brother.
@@windybassham3130 I wish the best for everyone who is looking for a cure. Lung cancer has metastasized to the liver. I hope treatment starts in Turkey as soon as possible. I hope your husband gets his best healthy life.
As always this is pure Gold!
Very helpful. Thank you.
Zulauf Ferry
I am a medical oncologist from Pakistan. I will say ur vidoes are amazing, watching them regularly. Learnt alot especially from the algorithm. Unfortunately Tx are for well developed countries. I would request you to involve Low income countries and ask them real world treatments they give and find the gaps
I am a medical oncologist from Pakistan. I will say ur vidoes are amazing, watching them regularly. Learnt alot especially from the algorithm. Unfortunately Tx are for well developed countries. I would request you to involve Low income countries and ask them real world treatments they give and find the gaps
Lois Shoal
Great work sir
Standard of care? How sad . Treating any and all cancer types using standard of care is like a cop showing up after the shooting is over … Treating radical cell division (cancer ) by trying to kill the cancer with radiation etc. instead of just cutting off what feeds the cancer and just starving it. Cancer feeds on only two foods Glutamine and glucose ( sugar ) thru fermentation …cut the carbs and feed your body on ketones Cancer can’t feed on ketones
Harris Thomas Perez Sandra Williams Frank
This was incredibly helpful and educational. Is there any new data regarding Nivo-AVD in pediatrics that I can look up for AS NSCHL in teens? I know it’s now the frontline for patients over 60 but curious if newer data shows it to be safe for the younger group as this video/research was over a year ago? Thanks for your channel and all you share
Keep it up, this is excellent.
My low risk mugs is now smoldering myeloma
Thank you so much for your great discussion
Thank you for telling the truth,the onco standards are 5 years after treatment is considered a cured case,but then the damaged cardio issues kill the patient,BUT the onco system says,0 NO this patient didnt die from cancer they died from a badly damaged cardiac system So ypu cant blame us oncos,,all while our onco system gained millions $$$$$$,,my elder father was caught by this trap, lucky i was able to stop this greedy process b4 it killed him
Amazing video!!!
Great overview, it would be great to have one final summary slide.
Hi. I’m 43 and I just was diagnosed with invasive lobular breast cancer with triple positive and BRCA1. Tumor size 8mm on MRI, 5mm on ultrasound. Just had a double mastectomy and waiting on pathology still after surgery to confirm size and if it has spread to lymph nodes. Seems rare to be lobular and HER2. Treatment with no spread is planned for 12 weeks of taxol and herceptin for 12 months with tamoxifen after. Any advice? Do you offer consults?
Look at cancer as a metabolic disease. You doctors need to watch dr seyfried
Thank you 🙏🏻
what about a elevated Kappa FLC, plus a high d-dimer (900)?
That was great. Thank you. When are you going to do the NET p and GI treatment with Mark Lewis? He is great. Can´t wait. I listen to you guys almost daily in Spotify
Next standard of care💪
I'm kappa light chain MGUS, but it's just 38.69, ratio 3.06. At what point would a bone marrow biopsy be done? When my ratio reaches 100? I understand the "watch and wait" in MGUS and SMM, but I thought a baseline BMB was standard after MGUS diagnosis via serum.
Thanks! Excellent discussion
Thank you!
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