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Andrew Dalby
United Kingdom
เข้าร่วมเมื่อ 26 ก.ย. 2006
This is a channel about data handling and statistical analysis.
It is called the accidental statistician because I ended up teaching and working in data handling and statistics completely by accident. This is also the title of an article by Sir David Cox about his career in statistics. I am never going to try and emulate him or his ability. I did have the honour of being in the same department for a while, even in his 80s he was still eager to learn more (he wanted to come to my classes on bioinformatics and systems biology). He was an amazing person and one of the genuine greats.
It is called the accidental statistician because I ended up teaching and working in data handling and statistics completely by accident. This is also the title of an article by Sir David Cox about his career in statistics. I am never going to try and emulate him or his ability. I did have the honour of being in the same department for a while, even in his 80s he was still eager to learn more (he wanted to come to my classes on bioinformatics and systems biology). He was an amazing person and one of the genuine greats.
Using BoxShade
This video uses Boxshade (junli.netlify.app/apps/boxshade/) online to create sequence alignment images that can be included in word documents.
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วีดีโอ
Using ConSurf
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This is an example of using ConSurf to look at the sequences differences between the Neuraminidase subtypes based on a structural and also a sequence analysis.
The change in Mann Whitney calculations
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The change in the way Mann-Whitney tests are carried out in SPSS after version 28
Yates Continuity Correction in SPSS
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the Yates continuity correction for the 2x2 table in SPSS
Why do we need statistics
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Showing why statistics matter and why we use them all the time
z tests
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Theory of the z-test: Note we almost always use t-test and this is just for information
Using SPSS with Enzyme Kinetics Data
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Analysing the enzyme kinetics data in SPSS
Using Excel with Enzyme Kinetics Data
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Using Excel to calculate the values for the enzyme kinetics data
Two Way Tables in SPSS Gender and Favourite Colour
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Two Way Tables in SPSS Gender and Favourite Colour
Two Way Tables in Excel Using a Pivot Table
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Two Way Tables in Excel Using a Pivot Table
Thinking about the Potato Osmosis Experiment
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Thinking about the Potato Osmosis Experiment
Summarising the Captopril data with Confidence Intervals in SPSS
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Summarising the Captopril data with Confidence Intervals in SPSS
Summarising Frequencies of Categorical Variables in SPSS
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Summarising Frequencies of Categorical Variables in SPSS
Summarising data correctly with standard errors and confidence intervals
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Summarising data correctly with standard errors and confidence intervals
The site is down now Could you have any suggestions
your video is amazing. Can you please make one explaining how to do this using the new website?
Thank you. I will try to when I get some free time as the changes are quite significant
Hi Andrew, thank you for uploading such a wonderful video.
How did you change the sscale on the x-axis please?
Hey Andrew, Great Videos! I recently came across your videos, and as a doctor pursuing research, they truly are gems! Keep up the good work.
Hi Andrew! I am doing a temporal analysis recently. I followed all the protocol but how can I finally get the mutation rate per site per year?? When I get the 'clock rate' in Tracer, it was far different from those I read in paper, I assumed there is any further calculation? That is really confusing for me because all the material didn't give an exact calculation while on the other hand this parameter was always seen in the related paper...
Dear Zhao, The problem is that BEAST calculates an effective population and mutation rate that cannot easily be separated. That is why the calculated rate will be nothing like the rate you see in the papers. If you have a big population even if you have a low clock rate the number of changes per generation will be relatively large. As the model cannot divide these two terms very easily I am not sure that you can work it out. It might be possible in a Bayesian Skyline analysis but again I think the quantities calculated are relative to one another.
Thanks for you reply! Actually I only run 10 Ecoli samples for now, the average size was about 5.1MB. I tested different models combination with default setting and choose exponential model. In Tracer it gave me a clock rate of 9.7E-2 while the rate I read from others were about 4~7E-7. Do you think I can work out a closer rate? @@accidental-statistician
Hey Andrew, this really helped me for Master Thesis! Do you have anything on how to conduct a meta-regression?