The Scientist Creative Services Division
The Scientist Creative Services Division
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Circumventing Cancer Resistance
Source:
www.podbean.com/eau/pb-unjwg-176a9b0
Traditional and new cancer therapies often become stymied due to tumor resistance, but why resistance arises and how to avoid it remain important questions in the cancer research field. To uncover the ways tumors form, adapt, and ultimately resist treatment, scientists investigate how genetic mutations arise and drive cancer cell evolution.
In this month’s episode, Deanna MacNeil from The Scientist spoke with Bishoy Faltas, an associate professor of medicine, and cell and developmental biology, and chief research officer of the Englander Institute for Precision Medicine at Weill Cornell, to explore bladder cancer evolution and treatment resistance.
The Scientist Speaks is a podcast produced by The Scientist’s Creative Services Team. Our podcast is by scientists and for scientists. We bring you the stories behind news-worthy molecular biology research.
มุมมอง: 6

วีดีโอ

Advances in Cell Therapy for Restoring Vision
มุมมอง 152หลายเดือนก่อน
Source: www.podbean.com/eau/pb-pagvr-1742e86 Retinal neurons derived from human stem cells are a promising source of replacement cells for regenerating damaged or diseased retinas. As scientists progress toward translation of cell therapies for restoring vision, they encounter challenges, including how to deliver the cells, ensure that they integrate appropriately with host tissue, and enable p...
Synthetic Screens, Genes, and De Novo Proteins: Training AI Models with More Sequence Diversity to I
มุมมอง 353 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-62aci-16cf9f8 Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutions to some of life’s biggest mysteries. From gene editing to protein engineering, synthesized DNA libraries enable researchers to grasp once unreachable high-throughput screening applications and disman...
Synthetic Screens, Genes, and De Novo Proteins: Multiplexed Gene Fragments Drive De Novo Protein Des
มุมมอง 343 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-wppmh-16c10ec Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutions to some of life’s biggest mysteries. From gene editing to protein engineering, synthesized DNA libraries enable researchers to grasp once unreachable high-throughput screening applications and disman...
Linking Fasting to Health and the Gut Microbiome
มุมมอง 244 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-hyhid-16b639a Gut microbes affect humans in many ways, including altering the gastrointestinal tract’s function and influencing a person’s body weight, and the nutrients that people ingest can affect the microbiome. Researchers now ask how popular weight loss strategies involving calorie restriction change the bugs in our guts and human health overall. In this epi...
Synthetic Screens, Genes, and De Novo Proteins: Engineering Gene Regulation through Creative Experim
มุมมอง 174 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-ew75v-16a687c Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutions to some of life’s biggest mysteries. From gene editing to protein engineering, synthesized DNA libraries enable researchers to grasp once unreachable high-throughput screening applications and disman...
Catch Me If You Can: Sequencing Screens for Rare Disease Genes
มุมมอง 935 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-r29uj-167c260 Rare diseases often remain undiagnosed due to unknown etiologies. In recent years, researchers have made headway in characterizing the molecular causes of rare diseases thanks to progressively powerful sequencing technologies, such as whole genome and exome sequencing. In this episode, Deanna MacNeil from The Scientist spoke with medical geneticist a...
Science Philosophy in a Flash: Demystifying Cell Culture Through Oxygen Analysis
มุมมอง 125 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-masrc-162ae66 With a track record of invention and translating technology into practical solutions, Walker Inman continues to drive innovation in the life sciences field. Inman is currently the cofounder and CEO of Lucid Scientific Inc., a company that develops cellular analysis tools. In this Science Philosophy in a Flash podcast episode brought to you by Lucid S...
Organoids in Space: The Next Frontier
มุมมอง 476 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-74mf7-164fd04 Building miniature brains may sound like a page out of a science fiction novel, but fact is indeed stranger than fiction. Researchers around the world grow brain organoids-3D miniature brains-to better understand brain development, aging, injury, and other disorders, as well as to test new treatment strategies. Some scientists take brain building to ...
Understanding the Effects of Extrachromosomal DNA on Cancer
มุมมอง 777 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-xed3c-1615945 In the 1960s, researchers in England noticed an anomaly when investigating chromosomes from surgically removed human tumors. Distinct from the intact chromosomes visible underneath the microscope were numerous “very small double chromatin bodies,” which are today better known as extrachromosomal DNA. Thanks to modern sequencing and imaging techniques...
Explainable AI for Rational Antibiotic Discovery
มุมมอง 518 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-sidyg-15f3797 Researchers now employ artificial intelligence (AI) models based on deep learning to make functional predictions about big datasets. While the concepts behind these networks are well established, their inner workings are often invisible to the user. The emerging area of explainable AI (xAI) provides model interpretation techniques that empower life s...
Natural Trip: Endogenous Psychedelics and Human Physiology
มุมมอง 649 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-cp8wq-15c47b6 The field of psychedelics research has exploded in recent years, as scientists dig deeper into the neuroscience and pharmacology of hallucinogens and how their unique properties can be harnessed to understand and treat depression, anxiety, post-traumatic stress disorder, Alzheimer’s disease, dementia, and neurodegenerative diseases. Remarkably, the h...
Epigenetics in a Dish
มุมมอง 7410 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-y9q8h-1594fa7 Every cell within the human body contains the same DNA, but not all cells look and act alike. The key to cellular diversity lies in which genes the cells express or shut down. Cells convey this information to the appropriate machinery through epigenetic modifications. In this episode, Charlene Lancaster from The Scientist spoke with Jonathan Weissman...
Virtual Laboratories for Remote Benchwork and Breakthroughs
มุมมอง 3611 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-m2piw-155e460 Cloud-based systems enable remote science experiments, allowing researchers to accomplish experimental breakthroughs from virtually any location with computer access. Remote labs and cloud-connected instruments are revolutionizing the way researchers approach benchwork, improving scientific discovery and education by enabling accessible and automated...
Science Philosophy in a Flash: Curiosity and Compassion Fuel Rare Disease Research
มุมมอง 2711 หลายเดือนก่อน
Source: www.podbean.com/eau/pb-chxk6-14effbc Lauren Drouin is the director of analytical development and the Genomic Medicine Unit at Alexion AstraZeneca Rare Disease. As a dynamic scientist with unique expertise in current research and industry trends for gene therapies, Drouin is passionate about driving progress within the rare disease field and advancing products from preclinical developmen...
Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering
มุมมอง 31ปีที่แล้ว
Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering
The Art and Science of Synthetic Biology
มุมมอง 58ปีที่แล้ว
The Art and Science of Synthetic Biology
Molecular Diagnostics: An Eye Toward the Future - Real Time Diagnostics: Improving HPV Screening wit
มุมมอง 46ปีที่แล้ว
Molecular Diagnostics: An Eye Toward the Future - Real Time Diagnostics: Improving HPV Screening wit
Smart Gateways into the Lab of the Future
มุมมอง 25ปีที่แล้ว
Smart Gateways into the Lab of the Future
Molecular Diagnostics: An Eye Toward the Future - Considerations for Oncology Biomarker Testing
มุมมอง 52ปีที่แล้ว
Molecular Diagnostics: An Eye Toward the Future - Considerations for Oncology Biomarker Testing
Science Philosophy in a Flash: Starting with Human Cell Systems
มุมมอง 16ปีที่แล้ว
Science Philosophy in a Flash: Starting with Human Cell Systems
Science Summarized: Smart Labs Connect Scientists, Instruments, and Data
มุมมอง 225ปีที่แล้ว
Science Summarized: Smart Labs Connect Scientists, Instruments, and Data
Molecular Diagnostics: An Eye Toward the Future - Modernizing Molecular Diagnostics, from Assay Deve
มุมมอง 40ปีที่แล้ว
Molecular Diagnostics: An Eye Toward the Future - Modernizing Molecular Diagnostics, from Assay Deve
Molecular Diagnostics: An Eye Toward the Future - The Simple Solution of Saliva
มุมมอง 20ปีที่แล้ว
Molecular Diagnostics: An Eye Toward the Future - The Simple Solution of Saliva
Science Philosophy in a Flash: Relevant Models Reflect Real-World Needs
มุมมอง 15ปีที่แล้ว
Science Philosophy in a Flash: Relevant Models Reflect Real-World Needs
Science Philosophy in a Flash: Targeting a Genetic Accident to Treat Disease
มุมมอง 16ปีที่แล้ว
Science Philosophy in a Flash: Targeting a Genetic Accident to Treat Disease
Considerations for a Successful PCR Set Up
มุมมอง 1.3Kปีที่แล้ว
Considerations for a Successful PCR Set Up
Building Bridges for Translational Research - Supporting mRNA Therapeutic Development and Beyond
มุมมอง 31ปีที่แล้ว
Building Bridges for Translational Research - Supporting mRNA Therapeutic Development and Beyond
Science Summarized: Putting Cells in Spatial Context
มุมมอง 206ปีที่แล้ว
Science Summarized: Putting Cells in Spatial Context
Science Summarized: The Mosaic Brain
มุมมอง 636ปีที่แล้ว
Science Summarized: The Mosaic Brain